크랙幅이 壓縮破壞强度에 미치는 影響

文秉秀,黃秀喆,吳範錫,趙鎭境 충북대학교 산업과학기술연구소 2002 산업과학기술연구 논문집 Vol.16 No.1

Under the compressive loads, tensile stress fields are possibly induced according to the boundary condition of compressed body. At the crack tip, the possibility of occurance of tensile stress fields are strong even under the compressive loads. In this paper, the fracturing behavior of brittle materials containing crack are investigated and the compressive strength affected by crack clearance are inspected theoretically and experimentally. Upon the theoretical and experimental results, it is found that compressive strength is decreased as the crack clearance is increased.

Phospholipase A₂활성억제와 관련한 시호 물추출액 및 시호 약침액의 항염증효능에 관한 연구

문진영,남경수,임종국 동국대학교 경주대학 1997 東國論集 Vol.16 No.2

농도별 시호 약침액과 시호 물 추출액을 대상으로 phospholipase A_2(PLA_2)에 대한 시호의 영향을 알아보기 위하여, 1-stearoyl-2-[1-^14C]arachidonyl-sn-glycerophosphocholine을 기질로 하여 Ⅰ형 PLA_2(porcine pancreas) 및 Ⅱ형 PLA_2(Crotalus atrox)의 활성에 대한 효과를 측정하여 다음과 같은 결과를 얻었다. 1) PLA_2 효소의 활성발현에 최적 배양시간이 어떠한지를 알아보기위해 pH 7.0에서 37℃에서 반응시간을 0분에서 180분간의 범위까지 기질의 농도를 20n㏖로 하여 porcine pancreas 및 Crotalus atrox 유래의 PLA_2를 대상으로 활성의 변화를 관찰한 결과, 반응시간이 길어질수록 두 효소의 활성이 점차로 증가하였다. 2) Porcine pancreas 유래의 Ⅰ형 PLA_2의 활성에 미치는 시호의 영향을 관찰한 결과, 시호 약침액은 최고 92%, 시호 물 추출액에서는 최고 94%의 PLA_2 활성 저해효과를 보였으며, 희석배수가 증가할수록 활성 저해효과는 감소하였다. 3) Crotalus atrox 유래의 Ⅱ형 PLA_2의 활성에 미치는 시호의 영향을 관찰한 결과, 시호 약침액은 최고 60%, 시호 물 추출액에서는 최고 55%의 PLA_2 활성 저해효과를 보였다. 또한 시호 약침액 및 물 추출액의 원액에서 4배 희석액까지는 40% 이상의 억제효능을 보인 반면, 8배 이상의 희석액부터는 활성 억제효능이 급격히 감소하였다. 이러한 결과로 미루어 볼 때 시호 약침액 및 시호 물 추출액은 모두 PLA_2에 대한 강한 억제활성이 있음을 알 수 있었다. 또한 PLA_2 효소의 유형별로 볼 때, 시호는 Ⅱ형 PLA_2에 대해서 보다 Ⅰ형 PLA_2에 대한 억제효능이 훨씬 강함을 알 수 있었다. 그리고 시호 약침액과 시호 물 추출액을 비교해보면 Ⅰ형 PLA_2에 대해서는 시호 물 추출액이, Ⅱ형 PLA_2에 대해서는 시호 약침액이 상대적으로 다소 강한 억제효능이 있음을 알 수 있었다. 본 연구의 결과에서 시호는 그 효능적 측면에서 항 염증제, 특히 PLA_2 저해제로 개발될 수 있는 가능성이 제시된다. Phospholipase A_2(PLA_2) is a key enzyme that catalyze the hydrolysis of the ester at the sn-2 position of cell membrane phospholipid to produce a lysophospholipid and arachidonic acid. Lysophospholipid is the precursor of platelet-activating factor(PAF). And arachidonic acid is the substrate for cyclooxygenase and lipoxygenase in the arachidonic acid cascade generating various eiconanoids such as prostaglandins, leukotrienes and thromboxanes. Thus, PLA_2 plays an important role in the pathogenesis of inflammation. Recently, compounds that inhibit PLA_2 activity have been received considerable attention as potential therapeutic agents in the treatment of inflammation. Bupleury radix has been used as a natural drug for fever, inflammation and liver disease in traditional medicine. This study was performed in order to investigate the inhibitory effects of Bupleury radix aqueous extract(BRAE) and aqua-acupuncture solution(BRAA) on activities of two different types of PLA_2. BRAE showed about 94% inactivation of group Ⅰ PLA_2 from porcine pancreas, and 55% inactivation of group Ⅱ PLA_2 from Crotalus atrox ultimately. And BRAA exhibited about 92% inactivation of group Ⅰ PLA_2, and 60% inactivation of group Ⅱ PLA_2. On the basis of these results, it is suggested that Bupleury radix might play a anti-inflammatory role by a mechanism that probably involves inactivation of PLA_2.

釜山地方의 年降水量 및 月降水量의 Anomaly level에 關한 硏究

文勝義,水縝 부산대학교 과학교육연구소 1979 교사교육연구 Vol.6 No.2

The annual and monthly precipitations in Pusan area for 1904-1974 were classified into five anomaly, levels and were analyzed statistically to know the frequency distribution and its characteristcs of each anomaly level. The results of this study are as follows: 1) The maximum frequency of anomaly levels occurs on LN-level and a level is not denoted higher or lower than S-lvel or GA-level in the annual precipitation. 2) In the monthly precipitations, there are no EA-levels in January, March, June, July, September, December and no MEA-levels except in January, February, June, and October.

다중 채널 동축 케이블의 초고주파 측정용 보드 설계

문수덕,김진규,황희용 강원대학교 산업기술연구소 2007 産業技術硏究 Vol.27 No.A

In High-Speed DSP systems, crosstalk between transmission lines of multi-channel can degrade the performance of equipment operations, This paper presents a microwave board to measure multi-channel coaxial cable assembly. The designed board has good performances from DC to 3 GHz, which have improved characteristic impedance, reduced crosstalk by using via fence, and low transmission loss. Using the designed board, we can measure characteristics of DUT(Device Under Test) such as return loss, insertion loss, crosstalk, phase delay, and characteristic impedance. The measured results are used to improve performances of a produced coaxial cable assembly.

柴胡가 free radical에 의한 脂質過酸化物 生成에 미치는 效果

문진영,최미정,남경수,임종국 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

Antioxidant effects of aqueous Siho extract on lipid peroxidation were determined by TBA value and also by lipid peroxidation value during the autoxidation of Iinoleic acid. Siho extracts exhibited markedly antioxidant aCtivity, which inhibited 99% of linoleic acid peroxidation. And Siho extracts showed 42% scavenging effect on α,α-dlphenyl-β-pjcrylhydrazyl radical, also exhibited a 60-94% inhibitory effect on superoxide generation. Siho extracts dose-dependently protected the cell death induced by tert-butyl hydroperoxide (t-BHP) and significantly increased cell viability In the normal rat liver cell(Ac2F) . These results suggested that Siho might play a protective role in lipid peroxidation by free radicals. Key Words: lipid peroxidation ; Siho extracts; scavenging effect

密陽 얼음골의 夏季結氷 現象에 關한 硏究

文勝義,黃水鎭 釜山大學校 師範大學 1977 교사교육연구 Vol.4 No.2

There are f reezing phenonena in summer at so called "Ice-valley" in the south-eastern part of the Korean peninsula. The purpose of this paper is to examine the causes of this ice-forming phenomena which can be explained by following causes. (1) As the valley is very deep and is toward the North, the insolations to the "Ice-valley" are very little through the year. Therefore, the under ground (15m from the surface) temperatures maintain about 6°C in summer. (2) The upper capillary zone is considered as a adiabatic situation because this zone is insulated from the solar radiation by the Talus having very large boulders(50-20G<* in dia.) (3) As the defferences of saturated vapor pressure between upper capillary zone and outside of the Talus are very high, the evaporization will be occur on the upper capillary zone. (4) Consequently, water is frozen by the loss of evaporization heat due to the evaporation at the upper capillary zone.

兄山강 流域의 汚染負荷量豫測에 관한 연구

文秋淵,朴鎭植,金秀生 동아대학교 환경문제연구소 1995 硏究報告 Vol.18 No.2

This study has performed to investigate and evaluate the amount of pollutants and the status of water quality of the Hyung-San River and prediction water pollution loads. In the field survey('94.11-'95.3), mean concentrations of BOD were found 0.78-4.90ppm, respectively, which were exceeding the second grade at inflow point of Sindang stream The predicted BOD pollution loads of Hyung-San river in 1996, 2001, 2006, 2011 were 13,068.3 kg/day, 13,003.1 kg/day, 9,355.6 kg/day, 9,506.6 kg/day.

비병원성 야생효모로부터 알칼리성 단백질분해효소 생산

문정수, 박경서, 공유리, 김수진, 이종수 배재대학교 자연과학연구소 2022 自然科學論文集 Vol.33 No.1

Cellulase 생산 야생효모의 선별 및 세포외 Cellulase 생산

문정수, 박경서, 김혜원, 김수진, 이종수 배재대학교 자연과학연구소 2016 自然科學論文集 Vol.33 No.1

제주도 양식넙치, Paralichthys olivaceus의 스쿠티카충병 발생 동향

진창남,이창훈,오상필,정용욱,송춘복,이제희,허문수 한국어병학회 2003 한국어병학회지 Vol.16 No.2

The research was carried out to know the occurrence trend of scuticociliatosis and mortality of fingerlings in flounder. The diseased fish were collected from on-land rearing farms and hatcheries of flounder in Jeju Island form January 1991 to December 2001. Occurrence of scuticociliatosis was about 10% of total occurred diseases for 1991 to 1996, but increased to 34.5% in 2001. Although monthly occurrence of seuticociliatosis was not related to season from 1999 to 2001, the highest occurrence was revealed in July and August. Mixed infections of bacteria including Vibrio sp., Edwardsiella tarda, Streptococcus sp., and Flexibacter sp., with seuticociliates were observed. Among the bacteria, Vibrio sp., was the highest frequency(40.1%), and the lowest one(10.1%) was Streptococcus sp., Mortality of fingerlings by seuticociliates was different sharply according to size of fish. Mortality of infected fingerlings below 7㎝ of total length was 53.8%, while that of normal fingerling above 7㎝ of total length was 13.2%. When fish were grown above 25㎝, mass mortality by seuticociliates infection was decreased markedly.