Stability of phenolic acids and the effect on weed control activity

Jiayu Li,Qi Zhang,Wenwen Hu,Xiaoyan Yang,Haibin He 한국응용생명화학회 2015 Applied Biological Chemistry (Appl Biol Chem) Vol.58 No.6

Phenolic acid is a very important class of allelochemicals with allelopathic weed control activity. In this study, three benzoic acid derivatives (syringic, 4-hydroxybenzoic, and vanillic acids), three cinnamic acid derivatives (cinnamic, 4-hydroxycinnamic, and ferulic acids) were tested, and high-performance liquid chromatography was used to conduct a dynamic analysis on the changes in the concentration of phenolic acids in a bioassay based on the initial concentration and test time. The results showed that the concentration of individual phenolic acids and a solution of mixed phenolic acids decreased to a certain extent irrespective of environment, i.e., bioassay (4–7 days) or a ricegrowing environment, and a significant decrease in concentration was measured after 48 h. Based on the above results, the laboratory bioassay was conducted using a fresh solution of phenolic acids every 48 h. The results showed that the instability of phenolic acid could affect its weed control activity, and this effect was more significant for high concentrations of phenolic acids. On the other hand, changing the solution did not have a significant impact on the weed control activity of phenolic acids in the natural environment (pH 6.50), in which allelopathic rice release phenolic acids. These results reveal the instability of phenolic acids could significantly reduce the inhibition rate on the growth index for receptor plants in an indoor bioassay.

贸易预期与国家间冲突:中越经济-安全联动研究

( Hu Jiayu ),( Chung Youngjune ) 대한정치학회 2022 大韓政治學會報 Vol.30 No.4

Does economic interdependence reduce the possibility of inter-state conflict? The economic-security nexus question has long been an enduring topic in the study of international politics. This article analyzes the economic-security interaction in China- Vietnam relations since their establishment of a comprehensive strategic cooperative partnership in 2008. Despite their deepening trade relations, the two countries have encountered frequent security conflicts, particularly in the South China Sea. To explain the causes of this phenomenon, the authors use the “trade expectation theory” to analyze the impact of economic interdependence for China-Vietnam conflicts. The study finds that Vietnam’s trade expectations with China is affected by relative gains, nationalism, and third-party intervention of great powers, which in turn, leads to the occurrence of frequent low-intensity conflicts. Next, the increase in Vietnam’s trade deficits vis-a-vis China led to the former’s alignment with the United States to decrease its vulnerability. Last, Vietnam’s potentially high economic costs of severing economic cooperation with China prevented low-intensity conflicts from escalating into high-intensity armed conflicts.

An autonomous radiation source detection policy based on deep reinforcement learning with generalized ability in unknown environments

Hu Hao,Wang Jiayue,Chen Ai,Liu Yang 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.1

Autonomous radiation source detection has long been studied for radiation emergencies. Compared to conventional data-driven or path planning methods, deep reinforcement learning shows a strong capacity in source detection while still lacking the generalized ability to the geometry in unknown environments. In this work, the detection task is decomposed into two subtasks: exploration and localization. A hierarchical control policy (HC) is proposed to perform the subtasks at different stages. The low-level controller learns how to execute the individual subtasks by deep reinforcement learning, and the highlevel controller determines which subtasks should be executed at the current stage. In experimental tests under different geometrical conditions, HC achieves the best performance among the autonomous decision policies. The robustness and generalized ability of the hierarchy have been demonstrated

Influencer Attachment and Consumer Response to Product Links in Native Video Ads: An Empirical Study on Bilibili's Platform

Hu, Jiayu,Chen, Mingyuan,유승철 한국인터넷방송통신학회 2024 International journal of advanced smart convergenc Vol.13 No.1

This study explores an innovative advertising technique on Bilibili, where product links are embedded as bullet comments visible only to mobile app users. The research involved 140 participants, divided equally between followers and non-followers of a popular influencer, ‘Gourmet WanggangR.’ These groups were further split, with half viewing a video containing the product link on the app and the other half via PC. The study revealed that influencer attachment significantly increased viewer immersion (transportation) and positively influenced attitudes towards the content, which in turn elevated purchase intentions. Importantly, the influencer’s followers showed a stronger attachment and more favorable attitudes towards the content, alongside a heightened likelihood to purchase the advertised product. The presence of the product link further accentuated these effects among the influencer’s followers. Conversely, in the absence of the link, the correlation between influencer attachment and content attitude was less pronounced. These findings highlight the effectiveness of embedding product links in video content as a marketing strategy, particularly when targeting an influencer’s followers through mobile platforms.

Stability of phenolic acids and the effect on weed control activity

Li, Jiayu,Zhang, Qi,Hu, Wenwen,Yang, Xiaoyan,He, Haibin 한국응용생명화학회 2015 Applied Biological Chemistry (Appl Biol Chem) Vol.58 No.6

Phenolic acid is a very important class of allelochemicals with allelopathic weed control activity. In this study, three benzoic acid derivatives (syringic, 4-hydroxybenzoic, and vanillic acids), three cinnamic acid derivatives (cinnamic, 4-hydroxycinnamic, and ferulic acids) were tested, and high-performance liquid chromatography was used to conduct a dynamic analysis on the changes in the concentration of phenolic acids in a bioassay based on the initial concentration and test time. The results showed that the concentration of individual phenolic acids and a solution of mixed phenolic acids decreased to a certain extent irrespective of environment, i.e., bioassay (4-7 days) or a ricegrowing environment, and a significant decrease in concentration was measured after 48 h. Based on the above results, the laboratory bioassay was conducted using a fresh solution of phenolic acids every 48 h. The results showed that the instability of phenolic acid could affect its weed control activity, and this effect was more significant for high concentrations of phenolic acids. On the other hand, changing the solution did not have a significant impact on the weed control activity of phenolic acids in the natural environment (pH 6.50), in which allelopathic rice release phenolic acids. These results reveal the instability of phenolic acids could significantly reduce the inhibition rate on the growth index for receptor plants in an indoor bioassay.

Emoji advertising in social media and its effects on consumer behavior: Assessing purchase intentions and brand metaphorical warmth

Chen, Mingyuan,Hu, Jiayu,유승철 한국인터넷방송통신학회 2024 International journal of advanced smart convergenc Vol.13 No.1

In digital marketing, the strategic use of emojis in social media advertising, particularly on the Xiaohongshu app, significantly influences consumer acceptance and purchase behavior. This study examines the impact of emoji-laden advertisements and the role of brand metaphorical warmth on consumer perceptions. Employing a tailored questionnaire, the research explores how emojis affect brand advertisement reception, filling a gap in empirical research on emoji advertising effectiveness. Findings indicate that emojis, when used judiciously, enhance consumer acceptance and contribute to a positive brand perception. However, excessive use may undermine trust. Brand metaphorical warmth emerges as a crucial factor, suggesting that emojis can effectively convey warmth, fostering a deeper emotional connection with consumers. These insights offer practical implications for refining social media marketing strategies, advocating for a balanced approach to emoji usage in advertisements to optimize engagement and influence consumer behavior.

Setosphapyrone C and D accelerate macrophages cholesterol effl ux by promoting LXRa/ABCA1 pathway

Ting Li,Jiayu Yin,Yubin Ji,Ping Lin,Yanjie Li,Zixun Yang,Shumei Hu,Jin Wang,Baihui Zhang,Saloni Koshti,Junfeng Wang,Chenfeng Ji,Shoudong Guo 대한약학회 2020 Archives of Pharmacal Research Vol.43 No.8

LXRα agonists have attracted signifi cant attentiondue to their potential biological activities on promotingcholesterol effl ux. This study was designed to investigatewhether setosphapyrone C and D have potential lipid-loweringcapacity and the underlying mechanisms in vitro. Ourdata showed that setosphapyrone C and D had weak cytotoxicitycompared to the liver X receptor α (LXRα) agonistT0901317. In RAW 264.7 macrophages, setosphapyroneC and D signifi cantly enhanced [ 3 H]-cholesterol effl ux by~ 21.3% and 32.4%, respectively; furthermore, setosphapyroneC and D enhanced the protein levels of ATP-bindingcassette transporter (ABC) A1 and LXRα by 58% and 69%,and 60% and 70% (8 μM), respectively; however, they had noeff ect on the protein levels of ABCG1 and scavenger receptorB type 1; additionally, they had minor eff ect on the mRNAexpression of lipogenic genes. Of note, setosphapyrone C and D signifi cantly enhanced LXRα/ABCA1pathway inmice primary macrophages. In BRL cells, setosphapyroneC and D signifi cantly improved the protein levels of ABCA1and ABCG1; setosphapyrone D signifi cantly enhanced theprotein expression of low-density lipoprotein. Collectively,setosphapyrone C and D with weak cytotoxicity exhibitedeff ective lipid-lowering eff ect via enhancing LXRα/ABCpathways. Setosphapyrones possess potential applicationfor the treatment of hyperlipidemic diseases.

Associations among Genetic Variants and Intracranial Aneurysm in a Chinese Population

Bingyang Li,Chongyu Hu,Junyu Liu,Xin Liao,Jiayu Xun,Manqian Xiao,Junxia Yan 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.7

Purpose: Genome-wide association studies (GWAS) have revealed that common variants on or near EDNRA, HDAC9, SOX17,RP1, CDKN2B-AS1, and RBBP8 genes are associated with intracranial aneurysm (IA) in European or Japanese populations. However,due to population heterogeneity, whether these loci are associated with IA pathogenesis in Chinese individuals is still unknown. The purpose of this study was to investigate associations among GWAS-identified loci and risk of IA in a Chinese population. Materials and Methods: A total of 765 individuals (including 230 IA patients and 535 controls) were involved in this study. Twelvesingle nucleotide polymorphisms (SNPs) of candidate loci were genotyped using the Sequenom MassARRAY platform. Associationswere analyzed using univariate or multivariate logistic regression analysis. Results: SNPs in CDKN2B-AS1 (especially rs10757272) showed significant associations with IA in dominant and additive models[odds ratio (OR), 2.99 and 1.43; 95% confidence interval (CI), 1.44–6.24 and 1.10–1.86, respectively]. A SNP near HDAC9 (rs10230207)was associated with IA in the dominant model (OR, 1.42; 95% CI, 1.01–1.99). One SNP near RP1 (rs1072737) showed a protectiveeffect on IA in the dominant model (OR, 0.66; 95% CI, 0.46–0.95), while another SNP in RP1 (rs9298506) showed a risk effect onIA in a recessive model (OR, 3.82; 95% CI, 1.84–7.91). No associations were observed among common variants near EDNRA,SOX17, or RBBP8 and IA. Conclusion: These data partially confirmed earlier results and showed that variants in CDKN2B-AS1, RP1, and HDAC9 could begenetic susceptibility factors for IA in a Chinese population.

From Fragmented Development to Three-Dimensional and Coordinated Development - Research on Renewal Strategies of Existing Underground Commercial Space in Harbin

Xue, Minghui,Su, Yiming,Hu, Jiayu Council on Tall Building and Urban Habitat Korea 2021 International journal of high-rise buildings Vol.10 No.1

In Harbin, a network of underground commercial spaces has been developed to occupy spaces that were originally created as civil defense shelters. With the gradual extension of the local metro rail system, the existing underground commercial space is no longer an isolated regional development, but a space that represents "three-dimensional city" and coordinated development taking place in many Chinese cities. Based on the analysis of the unique development process taken in underground space of Harbin, this paper summarizes three characteristics of its early model of "fragmented development" of underground space. By conducting a comprehensive field research and survey, the researchers analyzed 472 questionnaires related to the development trend, and proposed multi-level synergistic elements for the renewal and development of underground commercial space. The paper concludes by discussing the trend of "three-dimensional and collaborative development," suitable for the development needs of the new era, and the corresponding development strategies for the renewal of underground space.

Accelerated Time-of-Flight Magnetic Resonance Angiography with Sparse Undersampling and Iterative Reconstruction for the Evaluation of Intracranial Arteries

Hehan Tang,Na Hu,Yuan Yuan,Chunchao Xia,Xiumin Liu,Panli Zuo,Aurelien F. Stalder,Michaela Schmidt,Xiaoyue Zhou,Bin Song,Jiayu Sun 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.2

Objective: To compare the image quality of three-dimensional time-of-flight (TOF) magnetic resonance angiography (MRA) with sparse undersampling and iterative reconstruction (sparse TOF) with that of conventional TOF MRA. Materials and Methods: This study included 56 patients who had undergone sparse TOF MRA for intracranial artery evaluation on a 3T MR scanner. Conventional TOF MRA scans were also acquired from 29 patients with matched acquisition times and another 27 patients with matched scanning parameters. The image quality was scored using a five-point scale based on the delineation of arterial vessel segments, artifacts, overall vessel visualization, and overall image quality by two radiologists independently, and the data were analyzed using the non-parametric Wilcoxon signed-rank test. Contrast ratios (CRs) of vessels were compared using the paired t test. Interobserver agreement was calculated using the kappa test. Results: Compared with conventional TOF at the same spatial resolution, sparse TOF with an acceleration factor of 3.5 could reduce acquisition time by 40% and showed comparable image quality. In addition, when compared with conventional TOF with the same acquisition time, sparse TOF with an acceleration factor of 5 could also achieve higher spatial resolution, better delineation of vessel segments, fewer artifacts, higher image quality, and a higher CR (p < 0.05). Good-to-excellent interobserver agreement (к: 0.65–1.00) was obtained between the two radiologists. Conclusion: Compared with conventional TOF, sparse TOF can achieve equivalent image quality in a reduced duration. Furthermore, using the same acquisition time, sparse TOF could improve the delineation of vessels and decrease image artifacts.