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      • KCI등재후보

        The Prevalence of Os Acromiale in Korean Patients Visiting Shoulder Clinic

        Jayant Kumar,박원하,Seung-Ho Kim,이현일,유재철 대한정형외과학회 2013 Clinics in Orthopedic Surgery Vol.5 No.3

        Background: The prevalence of os acromiale has been documented to be between 1% and 15% and is known to be clinically associated with subacromial impingement or rotator cuff tear. However, the prevalence of os acromiale in Korea has not yet been determined. The purpose of this study is to evaluate the prevalence of os acromiale in Korean patients who visited shoulder clinics and to investigate the correlations with rotator cuff tear. Methods: We retrospectively reviewed the X-rays of patients visiting a shoulder clinic at a tertiary hospital in Korea from January 2011 to January 2012 to determine the frequency of os acromiale. X-ray findings were confirmed with magnetic resonance imaging (MRI) for patients who had these images available. MRI was also used to assess the status of the rotator cuff. The correlation between the presence of os acromiale either with gender, hand dominance or rotator cuff tear was analyzed statistically. Results: A total of 2,946 shoulders from 1,568 patients were analyzed with X-rays. Thirteen cases out of 1,568 patients had an os acromiale; and there were five and eight cases of pre-acromiale and meso-acromiale, respectively. Thus, the prevalence of os acromiale in this study population was found to be 0.7 (7 cases per 1,000 patients). Bilaterality was found in two cases. Os acromiale was not more frequent according to gender (five males versus eight females, p = 0.525) and hand dominance was not associated with frequency of os acromiale (seven dominant arms versus six non-dominant arms, p = 0.631). A sub-analysis of shoulders with available MRIs (1,074 shoulders) revealed that there were two rotator cuff tears (40%) out of five cases of os acromiale, whereas 607 rotator cuff tears were observed (57%) among 1069 cases without os acromiale. This difference was not statistically significant (p = 0.656). Conclusions: The identified prevalence of os acromiale in Korean patients who visited shoulder clinics is 0.7%, which is much lower as compared with the prevalence of general population from other ethnic groups. No correlation was observed between rotator cuff tears and os acromiale in this study population.

      • Presentation and Outcomes of Gastric Cancer at a University Teaching Hospital in Nepal

        Sah, Jayant Kumar,Singh, Yogendra P,Ghimire, Bikal Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.13

        Background: Gastric cancer is the most common gastrointestinal cancer and a leading cause of cancer mortality in Nepal. Survival of gastric cancer patients depends on the stage at which diagnosis is made. The aim of this study was to analyze the presentation and outcomes of gastric cancer patients treated at a tertiary care hospital in Nepal. Materials and Methods: A retrospective analysis of 140 consecutive histologically proven gastric adenocarcinoma cases managed at the Department of Surgery, Tribhuvan University Teaching Hospital, Kathmandu, Nepal for the period of January 2009 to December 2013 was carried out. Results: One hundred forty out of the total 186 patients with histologically proven gastric adenocarcinoma, were admitted for surgery. The mean age was $59.6{\pm}12.4yrs$ (range 29 to 78 yrs) and the male: female ratio was 2:1. Sixty three (45%) patients featured Tibeto-Burman descent though this ethnic group accounts for only 18% of the Nepalese population. Two-thirds or more patients presented with abdominal pain, anorexia, weight loss and/or vomiting. In 86 (61.5%) of the patients the tumor was located in the lower $3^{rd}$ of the stomach and in only 15% of the patients the tumor was located at the upper $3^{rd}$. Early gastric cancer was diagnosed postoperatively in only 4%. In 54%, the disease was locally advanced and metastatic lesions were found in 14% of the patients. Subtotal (73) or total (11) curative gastrectomies (D1, D1+ or D2) were performed in 84 (60%) patients with average lymph node retrieval of $16.6{\pm}8.2$. Palliative gastrectomies or procedures were performed in 23% of the patients and no intervention (open & close/biopsy) was employed in 15% of the patients. Perioperative morbidity was seen in 10% and mortality in 4%. Three, four and five year survival rates up to the recent follow-up were 17.9%, 11.9% and 8.3%, respectively. Conclusions: Gastric cancer in Nepal is usually diagnosed at an advanced stage and has a poor prognosis. Thus, early detection is the key to improve the survival of gastric cancer patients.

      • KCI등재

        Comparative Efficacy of Tamsulosin Versus Tamsulosin With Tadalafil in Combination With Prednisolone for the Medical Expulsive Therapy of Lower Ureteric Stones: A Randomized Trial

        Santosh Kumar,Kumar Jayant,Swati Agrawal,Shrawan Kumar Singh 대한비뇨의학회 2014 Investigative and Clinical Urology Vol.55 No.3

        Purpose: To compare the safety and efficacy of tamsulosin and tamsulosin with thephosphodiesterase-5 inhibitor tadalafil in combination with prednisolone as medicalexpulsive therapies for lower ureteric stones. Materials and Methods: Between July 2011 and December 2012, 62 adult patients presentingwith distal ureteric stones sized 5 to 10 mm were randomized equally to treatmentwith tamsulosin (group A) or tamsulosin with tadalafil (group B). Therapy wasgiven for a maximum of 6 weeks. In addition, patients in groups A and B were given5-mg prednisolone once daily (maximum 1 week). The stone expulsion rate, time tostone expulsion, analgesic use, number of hospital visits for pain, follow-up and endoscopictreatment, and adverse effects of the drugs were noted. Statistical analyses weredone by using Student t-test and chi-square test. Results: There was a higher expulsion rate (83.9% in group B and 74.2% in group A)and a lower time to expulsion in both treatment groups than in historical controls usedin earlier studies. However, these results were not statistically significant (p=0.349,p=0.074, respectively). Statistically significant differences were noted in hospitalizationfor colic and analgesic requirement, which were less in group B than in groupA. There were no serious adverse events. Another important finding was improvementin erectile function in group B. Conclusions: Medical expulsive therapy for distal ureteric stones using tamsulosin andtadalafil with prednisolone is safe and efficacious. Also, the prescription of tadalafilin cases of erectile dysfunction with the development of lower ureteric stones may provideadditional advantages.

      • KCI등재

        Role of Chromium Content on the Microstructure and Mechanical Properties of Lanthana Based Ferritic ODS Steels

        Ashwani Kumar,Bhagyaraj Jayabalan,Chetan Singh,Jayant Jain,Subrata Mukherjee,Krishanu Biswas,Sudhanshu S. Singh 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.4

        In the current study, lanthana (La2O3) based oxide dispersion strengthened (ODS) ferritic steels (Fe–xCr–1Ti–1W–0.5L2O3,x = 14, 18, 22, and 26, in wt%) have been fabricated by mechanical alloying and spark plasma sintering. The role of chromium(Cr) content and maximum sintering temperature (1050 and 1100 °C) on the density, microstructure and mechanical propertiesof the ODS steels have been studied. TEM analysis of the alloy revealed the presence of nano-sized (2–8 nm) complexoxide particles, i.e., La–Ti–Cr–O. Mechanical properties were estimated in terms of micro-hardness, nano-hardness, Young’smodulus and compressive strength. The highest micro-hardness (988 ± 11.3 HV) and compressive strength (2322 ± 49 MPa)were exhibited by the alloy having 26 wt% Cr, sintered at 1100 °C. The contribution of dispersion strengthening towards thestrength was calculated to be the highest (~ 72%). Overall, increasing the Cr content improved both the room temperaturecompressive strength as well as the compressive fracture strain.

      • SCOPUSKCI등재

        Clinical Presentation and Management of Eyes with Globe Perforation during Peribulbar and Retrobulbar Anesthesia: A Retrospective Case Series

        Naresh Babu,Jayant Kumar,Piyush Kohli,Ashish Ahuja,Prerana Shah,Kim Ramasamy 대한안과학회 2022 Korean Journal of Ophthalmology Vol.36 No.1

        Purpose: To evaluate the clinical presentation, management, and outcome of eyes with an inadvertent globe perforationduring peribulbar or retrobulbar block. Methods: This retrospective study evaluated the eyes which had an accidental globe perforation during local ocular anesthesiafrom 2012 to 2020. The patients were divided into three groups: group 1, Clear media with no rhegmatogenous retinaldetachment (RRD); group 2, significant vitreous hemorrhage (VH) precluding the retinal view without RRD; and group 3, RRDwith/without VH. Results: Twenty-five patients were included in the study. The mean axial length (AL) was 24.7 ± 2.7 mm (range, 20.9–31.2mm). The most common presenting feature was VH (n = 14). The treatment included retinal laser barrage (n = 7) and vitrectomy(n = 17). Retinal breaks were identified in all the eyes (total breaks = 37). The mean presenting best-corrected visual acuityin groups 1, 2, and 3 were logarithm of the minimum angle of resolution 0.79 ± 0.73, 1.82 ± 0.78, and 2.13 ± 0.59 respectively. All the treated patients had an attached retina at the last follow-up. The mean final best-corrected visual acuity for eachgroup was logarithm of the minimum angle of resolution 0.59 ± 0.79, 0.48 ± 0.26, and 1.25 ± 0.64, respectively (p = 0.006). The development of RRD was associated with a larger AL (p = 0.015); while the development of significant VH associated withthe superior location of the perforation (p = 0.015), late recognition of the perforation (p = 0.004), and multiple perforations (p= 0.015). Conclusions: Early recognition and intervention in eyes with an inadvertent perforation can lead to a good outcome. Eyeswith a longer AL, superior, and multiple perforations are at higher risk of developing complications like RRD and VH. Complicationslike RRD, macular injury, and vascular occlusion are risk factors for poor prognosis.

      • KCI등재

        Black Carbon Concentration during Spring Season at High Altitude Urban Center in Eastern Himalayan Region of India

        Khushboo Sharma,Rakesh Kumar Ranjan,Sargam Lohar,Jayant Sharma,Rajeev Rajak,Aparna Gupta,Amit Prakash,Alok Kumar Pandey 한국대기환경학회 2022 Asian Journal of Atmospheric Environment (AJAE) Vol.16 No.1

        This study analyzed the BC associated with PM1 and the contribution of biomass burning to the BC using a portable seven-channel Dual spot Aethalometer in and around Gangtok, the capital city of Sikkim, India, during April 2021. Additionally, CO2 and meteorological parameters (Temperature, Pressure, and Relative Humidity) was measured. The minimum concentration of BC was found in rural areas where the contribution of biomass burning to the BC is highest. The observed spatial variability of BC over Gangtok Municipal Corporation (GMC) area is minimal. Five days back-trajectory analysis was done using the Hybrid Single Particle Lagrangian Integrated Trajectory (HYSPLIT) model to understand the regional influences of air masses at Gangtok. The air mass of the studied region is under influence of trans-regional transport from Indo-Gangetic Plains affecting the BC concentration over the studied region. The black carbon presence in the ambient air near the glacier heights in the Eastern Himalayan region may significantly cause localized warming, thereby enhancing glacier melts. The results have significant bearing for the policy-makers to take corrective steps in addressing the issue of rising BC concentration in high altitude regions. A further detailed study is needed to examine the effect of BC on radiative forcing and its large-scale effect on the East Asian summer monsoon using regional climate models.

      • KCI등재

        An Unusual Case of Delirium after Restarting Clozapine

        Sourav Khanra,Rati Ranjan Sethy,Sanjay Kumar Munda,Christoday Raja Jayant Khess 대한정신약물학회 2016 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.14 No.1

        Clozapine is a gold standard medication and drug of choice in refractory schizophrenia. Among many of its fatal side effects, delirium is less reported and inconsistently recognized by clinicians. We here present a case of delirium which emerged during retreatment with clozapine in a patient of paranoid schizophrenia. A patient diagnosed with paranoid schizophrenia, was restarted on clozapine after he left medications and became symptomatic. He was delirious on 22nd day after clozapine was restarted. Clozapine was stopped and the patient was managed with standard treatment for delirium. After one week interval, clozapine was restarted. Delirium was not noted till 6 weeks of his hospital stay. Clozapine induced central anticholinergic toxicity or clozapine induced seizure might cause delirium in index case. Limited literature exist delirium with clozapine. Clinicians must have high index of suspicion to detect delirium during clozapine therapy. More researches should focus to explore the association between delirium and clozapine.

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