http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Steer-By-Wire 시스템의 Fault-Tolerant 기술 개발
김재석,이운성 국민대학교 생산기술연구소 2004 공학기술논문집 Vol.27 No.-
The Steer-By-Wire (SBW) system replaces complex mechanical linkages of the current steering system with electric motors, sensors, and electronic control units. However, the SBW system should guarantee its safety before commercialization, and therefore, a reliable and robust fault-tolerant technology has to be implemented. This paper presents fault-tolerant control strategy for a reliable and safe SBW system and proposes a fault-tolerant SBW control system integrating SBW control algorithms, fault-detection algorithms, and reconfiguration algorithms. Based on careful analysis on propagation effects of sensor faults, a reliable fault-tolerant control strategy has been developed. The fault-tolerant controller consists of a fault detection part that monitors and defects faults in the steering wheel and road wheel sensors, and a reconfiguration part that switches to normal sensor signal based on fault detection information. It has been demonstrated that the proposed algorithm detects sensor faults accurately and enables reliable steering control under various dynamic fault situations.
모형을 이용한 밀폐형 육계사의 환기 제어를 위한 유체 흐름 분석
유정상 ( Jung-sang Yoo ),이찬미 ( Chanmi Lee ),김재석 ( Jaesuk Kim ),박동혁 ( Donghyeok Park ),양도이 ( Doee Yang ),이중용 ( Joong Yong Rhee ) 한국농업기계학회 2020 한국농업기계학회 학술발표논문집 Vol.25 No.2
조류인플루엔자, 전염병을 방지하기 위해 무창형 밀폐형 계사가 늘어남에 따라 실내 환기 제어가 어느 때 보다 중요하게 여겨지고 있다. 이산화탄소 농도는 병아리 시절의 폐사율과 성장률에 영향을 미칠 뿐만 아니라 실내 작업자의 건강에도 해로운 영향을 미친다. 본 연구에서는 환기 입출구 위치에 따른 환기 효율성 비교와 CFD 시뮬레이션을 통한 실내 모형에서의 공기 흐름을 분석하기 위한 기초 기술을 개발하고자 한다. 실험을 위해 실제 밀폐 계사의 1:20의 축소 모형을 만들어 아두이노 우노(Arduino-UNO), 팬모터(SZH-GNP513, 5,000RPM) 그리고 이산화탄소 센서(Sensirion, SCD-30)를 사용하여 6,000ppm 이후의 팬모터 위치 변화와 1,500ppm, 3,000ppm에서의 릴레이 제어를 통한 환기 속도를 비교하였으며 이에 따른 유체 흐름을 분석하였다. 실험 결과 팬모터의 바람 출구가 아래에 있는 경우가 위에 있는 경우보다 약 117% 환기가 더 빨랐으며 3,000ppm 이하 1,500ppm 이상의 환기에서는 약 121% 환기가 빠른 것으로 나타났다. 유체 흐름 분석에서는 두 실험 모두에서 환기가 균등하게 되지 않은 것을 확인할 수 있었다. 이러한 결과는 실제 계사에서 육계와 작업자에게 쾌적한 이산화탄소 비율을 유지하기 위한 향후 밀폐형 계사 환기 연구에 활용이 될 수 있을 것이다.
Development of the Computerized Mathematics Test in Korean Children and Adolescents
Lee, Eun Kyung,Jung, Jaesuk,Kang, Sung Hee,Park, Eun Hee,Choi, InWook,Park, Soowon,Yoo, Hanik K. Korean Academy of Child and Adolescent Psychiatry 2017 소아청소년정신의학 Vol.26 No.1
Objectives: This study was conducted in order to develop a computerized test to measure the level of mathematic achievement and related cognitive functions in children and adolescents in South Korea. Methods: The computerized Comprehensive Learning Test-Mathematic (CLT-M) consists of the whole number computation test, enumeration of dot group test, number line estimation test, numeral comparing test (magnitude/distance), rapid automatized naming test, digit span test, and working memory test. To obtain the necessary data and to investigate the reliability and validity of this test, 399 children and adolescents from kindergarten to middle school were recruited. Results: The internal consistency reliability of the CLT-M was high (Cronbach's alpha=0.76). Four factors explained 66.4% of the cumulative variances. In addition, the data for all of the CLT-M subtests were obtained. Conclusion: The computerized CLT-M can be used as a reliable and valid tool to evaluate the level of mathematical achievement and associated cognitive functions in Korean children and adolescents. This test can also be helpful to detect mathematical learning disabilities, including specific learning disorder with impairment in mathematics, in Korea.
Development of the Computerized Mathematics Test in Korean Children and Adolescents
Eun Kyung Lee,Jaesuk Jung,Sung Hee Kang,Eun Hee Park,InWook Choi,Soowon Park,Hanik K. Yoo 대한소아청소년정신의학회 2017 소아청소년정신의학 Vol.28 No.3
Objectives: This study was conducted in order to develop a computerized test to measure the level of mathematic achievement and related cognitive functions in children and adolescents in South Korea. Methods: The computerized Comprehensive Learning Test-Mathematic (CLT-M) consists of the whole number computation test, enumeration of dot group test, number line estimation test, numeral comparing test (magnitude/distance), rapid automatized naming test, digit span test, and working memory test. To obtain the necessary data and to investigate the reliability and validity of this test, 399 children and adolescents from kindergarten to middle school were recruited. Results: The internal consistency reliability of the CLT-M was high (Cronbach’s alpha=0.76). Four factors explained 66.4% of the cumulative variances. In addition, the data for all of the CLT-M subtests were obtained. Conclusion: The computerized CLT-M can be used as a reliable and valid tool to evaluate the level of mathematical achievement and associated cognitive functions in Korean children and adolescents. This test can also be helpful to detect mathematical learning disabilities, including specific learning disorder with impairment in mathematics, in Korea.
( Sun Mi Gu ),( Sung Yeon Kim ),( Santosh Lamichhane ),( Jin Tae Hong ),( Jaesuk Yun ) 한국응용약물학회 2019 Biomolecules & Therapeutics(구 응용약물학회지) Vol.27 No.4
Limonene is a cyclic terpene found in citrus essential oils and inhibits methamphetamine- induced locomotor activity. Drug dependence is a severe neuropsychiatric condition that depends in part on changes in neurotransmission and neuroadaptation, induced by exposure to recreational drugs such as morphine and methamphetamine. In this study, we investigated the effects of limonene on the psychological dependence induced by drug abuse. The development of sensitization, dopamine receptor supersensitivity, and conditioned place preferences in rats was measured following administration of limonene (10 or 20 mg/kg) and methamphetamine (1 mg/kg) for 4 days. Limonene inhibits methamphetamine- induced sensitization to locomotor activity. Expression of dopamine receptor supersensitivity induced by apomorphine, a dopamine receptor agonist, was significantly reduced in limonenepretreated rats. However, there was no significant difference in methamphetamine-induced conditioned place preferences between the limonene and control groups. These results suggest that limonene may ameliorate drug addiction-related behaviors by regulating postsynaptic dopamine receptor supersensitivity.
국내 아동 및 청소년 난독증 진단을 위한 종합학습능력평가도구-읽기의 표준화 연구
유한익(Hanik K. Yoo),정재석(Jaesuk Jung),이은경(Eun Kyung Lee),강성희(Sung Hee Kang),박은희(Eun Hee Park),최인욱(InWook Choi) 대한소아청소년정신의학회 2016 소아청소년정신의학 Vol.27 No.2
Objectives: The aim of this study was to develop the computerized Comprehensive Learning Test-Reading (CLT-R) to evaluate the cognitive processes and achievements related to their basic reading ability and identify dyslexia in children and adolescents in South Korea. We also obtained the normative data and evaluated the reliability and validity of the test. Methods: We developed the CLT-R, including the word attack/nonword decoding, paragraph reading, sound blending, nonword repetition, rapid automatized naming, letter-sound matching, visual attention, orthography awareness, and digit span tests, for the purpose of diagnosing dyslexia. We investigated the reliability and validity of the tests and gathered the normative data from 399 subjects (male 48.9%), aged 5-14 years, from the last grade in kindergarten to middle school, dwelling in Seoul and Gyeonggi Province, South Korea. Results: No statistical differences were observed between the means of the tests and retests of the CAT. The mean of the correlation coefficient of the test-retest scores was 0.85. According to the construct validity test calculated by principal constant analysis using the oblique rotation method, 4 factors explained 70.0% of the cumulative variances. In addition, the normative data were obtained for all of the CLT-R subtests. Conclusion: The computerized CLT-R can be used as a reliable and valid tool to evaluate the reading achievement and reading related cognitive process in Korean children and adolescents in schools, clinics, and research institutes.
Significance of chitinase-3-like protein 1 in the pathogenesis of inflammatory diseases and cancer
Yu Ji Eun,Yeo In Jun,Han Sang-Bae,Yun Jaesuk,Yun Jaesuk,Yong Yoon Ji,Lim Young-soo,Kim Tae Hun,Son Dong Ju,Hong Jin Tae 생화학분자생물학회 2024 Experimental and molecular medicine Vol.56 No.-
Chitinase-3-like protein 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation, macrophage polarization, apoptosis, and carcinogenesis. The expression of CHI3L1 is strongly upregulated by various inflammatory and immunological diseases, including several cancers, Alzheimer’s disease, and atherosclerosis. Several studies have shown that CHI3L1 can be considered as a marker of disease diagnosis, prognosis, disease activity, and severity. In addition, the proinflammatory action of CHI3L1 may be mediated via responses to various proinflammatory cytokines, including tumor necrosis factor-α, interleukin-1β, interleukin-6, and interferon-γ. Therefore, CHI3L1 may contribute to a vast array of inflammatory diseases. However, its pathophysiological and pharmacological roles in the development of inflammatory diseases remain unclear. In this article, we review recent findings regarding the roles of CHI3L1 in the development of inflammatory diseases and suggest therapeutic approaches that target CHI3L1.
In Jun Yeo,Ji Eun Yu,Sung-Hyun Kim,Dae Hwan Kim,Miran Jo,Dong Ju Son,Jaesuk Yun,Sang-Bae Han,Jin Tae Hong 대한약학회 2024 Archives of Pharmacal Research Vol.47 No.4
The relationship between schizophrenia (SCZ) and cancer development remains controversial. Based on the disease-geneassociation platform, it has been revealed that tumor necrosis factor receptor (TNFR) could be an important mediatory factorin both cancer and SCZ development. TNF-α also increases the expression of brain-derived neurotrophic factor (BDNF)and tropomyosin receptor kinase B (TrkB) in the development of SCZ and tumor, but the role of TNFR in mediating theassociation between the two diseases remains unclear. We studied the vital roles of TNFR2 in the progression of tumor andSCZ-like behavior using A549 lung cancer cell xenografted TNFR2 knockout mice. TNFR2 knockout mice showed signifi -cantly decreased tumor size and weight as well as schizophrenia-like behaviors compared to wild-type mice. Consistent withthe reduced tumor growth and SCZ-like behaviors, the levels of TrkB and BDNF expression were signifi cantly decreased inthe lung tumor tissues and pre-frontal cortex of TNFR2 knockout mice. However, intravenous injection of BDNF (160 μg/kg) to TNFR2 knockout mice for 4 weeks increased tumor growth and SCZ-like behaviors as well as TrkB expression. Inin vitro study, signifi cantly decreased cell growth and expression of TrkB and BDNF by siTNFR2 transfection were found inA549 lung cancer cells. However, the addition of BDNF (100 ng/ml) into TNFR2 siRNA transfected A549 lung cancer cellsrecovered cell growth and the expression of TrkB. These results suggest that TNFR2 could be an important factor in mediatingthe comorbidity between lung tumor growth and SCZ development through increased TrkB-dependent BDNF levels.