원발성 자궁내막 편평상피암 1 예

한상원,홍순원,정동원,홍민,김남식,양석우 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.9

Primary endometrial squamous cell carcinoma is extremely rare, with only 64 cases repo- rted in the literature. In 1928 Fluhmann proposed three criteria for differentiating primary from secondary endometrial squamous cell carcinoma:(1) no coexisting endometrial adenocarcinoma (2) no connection between the endometrial tumor and the squamous epithelium of the cervix, and (3) no squamous cell carcinoma of the cervix present. Several authors have modified these criteria in their case presentations. Kay accepts the presence of an in situ cervical carcinoma, if there is no connection between cervical carcinoma in situ and the endometrial tumors. We have experienced a case of simultaneous carcinoma in situ of the cervix and endomet- rial squamous cell careinoma. This case was treated with chemotherapy(cisplatin, 5-fluoruracil) and external radiation following extended hysterectomy and bilateral salpingooophorectomy We report this case with a review of the concerned literatures.

불완전 고환성 여성화 증후군 1 예

홍석우(SW Hong),허의종(EJ Hur),박형무(HM Park),김우균(WK Kim),배도환(DH Pai) 대한산부인과학회 1987 Obstetrics & Gynecology Science Vol.30 No.12

본 중앙대학교 의과대학 산부인과학교실에서는 임상증상 및 내분비학적 검사로 진단된 불완전 고환성 여성화 증후군 1예를 경험 하였기에 간단한 문헌고찰과 함께 이를 보고하는 바이다. Incomplete testicular feminization syndrome is an ill-defined designation used to lescribe a heterogenous group of patients with an atypical form of testicular feminization. As in complete testicular feminization syndrome, the karyotype is XY, bilateral testes and other male internal genitalia are present, and mullerian derivatives are absent; however, unlike individuals with the complete testicular feminization syndrome, the external genitalia are ambiguous rather than that of female and some degree of virilization such as clitorial hypertrophy, partial labioscrotal fusion and hirsutism occurs at puberty. Complete and incomplete testicular feminization syndrome have been shown to be a disorder of androgen receptor function or genomic expression perse. More than 200 cases, complete and incomplete type, have been reported in the world. In our country, four cases of complete type have been reported up to present. We first report a case of incomplete testicular feminization syndrome with the brief review of literatures.

지장아를 동반한 쌍태임신 1 례

홍석우(SW Hong),이미영(MY Lee),문진수(JS Moon),배도환(DH Pai) 대한산부인과학회 1987 Obstetrics & Gynecology Science Vol.30 No.2

본 중앙대학교 의과대학 산부인과학교실에서는 임신 32주에 전전치태반으로 응급제왕절개술을 실시한 임산부에서 제 2아가 지장아였던 쌍태임신 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다 Fetus papyraceus is a rare and interesting condition occuring in multiple gestation We present a case of the fetus papyraceus in twin pregnancy with review of literatures

서울시내 5개종합병원의 임산부의 인구학적 산과학적 배경

홍성봉(SB Hong),김승욱(SW Kim),곽현모(HM Kwak),권순욱(SW Kwon),이재현(JH Lee),이원기(WK Lee),박인서(IS Park) 대한산부인과학회 1978 Obstetrics & Gynecology Science Vol.21 No.4

* This investigation received financial support from the World Health Organization. * 본 논문의 요지는 1977년 10월 7일 제 40차 대한산부인과학회 학술대회에서 발표하였음. 1)고려대학교 의과대학, 2)국립서울대학교 의과대학, 3)연세대학교 의과대학, 4)5)6)경희대학교 의과대학, 7)국립의료원 Changes in the value system among Korean along with the remarkable socioeconomic development during the last three decades ever since the out-break of Korean conflicts in 1950 have ushered in nationwide movement toward family limitation. Its consequence is obviously being reflected on the reproductive patterns of Korean couples. This paper is to clarify the recent changes in reproductive pattern in terms of demographic and obstetric backgrounds of Korean wives who attended five antenatal clinics of four university hospitals and one government hospital. Primary purpose of the study was intended to investigate possible effect of induced abortion on the outcome of subsequent pregnancies. The study was carried out by interviewing the pregnant women during pregnancy and after its termination in prospective fashion. The period of contack encompassed from February, 1975 to May, 1977. Each individual was contacted twice in pregnancy and after childbirth respectively. The results obtained from the first interview of 5,843 women at antenatal clinics are as follows: 1) Women attending antenatal clinics comprises of 19 years or less for 0.2%, 20-24 years for 20.1%, 25-29 years for 57.9%, 30-34 years for 18.5%, and 35-39 years for 2.9%. Thus, women in 20s represents 78.0% of all samples. Of these primigravidae is 36.5%, while multiparae 54.3% of the total. In comparison of women 10 years earlier in Seoul, the proportion of pregnant women in 30s were 37% instead of 22.8% of the present level which is mirroring the earlier limitation of family size by much shortened reproductive activities. 2) As to educational attainments of pregnant women, the proportion of wives completed middle or high school and college are 51.8% and 43.1% respectively, whereas the comparable educational levels among wives in Seoul are 45% and 5%. Therefore, the samples appear to be representative of women in much higher socioeconomic strata of Seoulite. 3) All women have experienced 1.5 pregnancies on average in their past, while among those ever experi

방광내 전기자극 시 나타나는 방광의 구심성 신경의 변화

홍창희,김영식,김장환,노지연,고혜경,김찬수,한상원 大韓泌尿器科學會 2003 Korean Journal of Urology Vol.44 No.5

척수절단 흰쥐에서 방광 내 전기자극치료 후 방광 구심성신경 신경펩티드의 변화

홍창희,김영식,김장환,노지연,고혜경,김찬수,한상원 大韓泌尿器科學會 2003 Korean Journal of Urology Vol.44 No.4

인간 난자의 체외수정 및 배아의 자궁내 이식 후 임신된 환자에서 혈중 β-hCG 측정에 의한 임신 결과 예측에 관한 연구

한상원,한혁동,이영진,박기환,홍민,오준환 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.10

체외수정 및 배아의 자궁내이식 후 임신 성공률은 약제의 종류 및 센타에 따라서 다양하지만 그렇게 높은 편은 아니다. 더구나 이들 임신이 모두 만삭까지 유지되어 출산하는 것은 결코 아니며, 일시적인 임신이나 자연유산 심지어 자궁외 임신으로도 임신지속에 실패할 수 있다. 또 여러 개의 배아를 자궁내에 이식하므로 다태아 임신의 가능성도 높다. 그러므로 장차 임신이 정상적으로 유지될 수 있는가에 대한 예후를 임신 초기에 추정하는 것은 큰 도움이 될 수 있을 것이다. 연세대학교 원주의과대학 원주기독병원 산부인과 불임클리닉에서 체외수정시술을 시행하여 임신된 환자 중 임신 결과가 확인된 165명을 대상으로 배아 이식 후 16 일째 혈중 β-hCG를 측정하여 각각의 임신 결과와 비교 분석하여 다음과 같은 결과를 얻었다. 1. 165예의 임신된 환자 중 다태임신은 40명(24.2%)이 었고, 임신지속 실패는 62명(37.6%)이었다. 2. 다태임신은 배아 이식 후 16일째 혈중 β-hCG의 평균값이 3820.15±2712.21 IU/ml으로 가장 높은 평균값을 보였으며 단태임신에 비교하여 유의하게 높았다(p value <0.05). 3. 임상전기 유산은 혈중 β-hCG의 평균값이 242.43± 234.69 IU/ml로 가장 낮은 평균값을 보였으며 단태임신에 비교하여 유의하게 낮았다(p value<0.05). 4. 임상적 유산은 배아 이식 후 16일째 혈중 β-hCG의 평균값은 1098.50±638.43 IU/ml으로 단태임신의 혈중 β-hCG의 평균값이 1444.02±908.03 IU/ml 비하여 약간 낮은 평균값을 보였으나 통계학적인 유의한 차이가 없었다(p value>0.05). 5. 자궁외임신은 혈중 β-hCG의 평균값이 681.20± 906.16 IU/ml으로 단태임신에 비해 약간 낮은 평균값을 보였으나 본 연구에서는 5명으로 사례가 작아 단태임신과의 유의한 비교는 불가능 하였다. 6. 배아 이식 후 16일째 혈중 β-hCG 분포에 따른 임신 유형별 환자 수를 비교하면 혈중 β-hCG값 20∼500 IU/ml에 46명의 환자 중 임신이 유지된 환자는 5명(11%) 이며 34명이 임상전기 유산(74%)으로 가장 많았고, 혈중 β-hCG값 501∼2000 IU/ml에 80명의 환자 중 임신이 유지된 환자는 62명(78%)이며 47명이 단태임신(59%)으로 가장 많았고, 혈중 β-hCG값 2001 IU/ml 이상에 39명의 환자 중 임신이 유지된 환자는 36명(92%)이며 25명이 다태임신(63%)으로 가장 많았다. 본 연구 결과 배아 이식 후 16일째 혈중 β-hCG 측정 에 의한 감별 진단은 임상전기 유산 및 다태임신의 진단 시 유용한 지표로 사용될 수 있을 것으로 사료된다. Serum level of β-subunit of human chorionic gonadotropin (β-hCG) at the post-ET day 16 was studied to evaluate its predictability of pregnancy outcome in 165 patients in vitro fertilization and embryo transfer (IVF-ET), which included 63 singleton pregnancies, 40 multiple pregnancies, 37 preclinical abortions, 20 clinical abortions and 5 ectopic pregnancies. In comparison to normal singleton pregnancies, multiple pregnancies showed significantly higher serum β-hCG level and preclinical abortions showed significantly lower serum β-hCG level, but Clinical abortions and ectopic pregnancies didn`t showed statistical significance level of serum β-hCG. In conclusion, determination of serum β-hCG level at post-ET day 16 is a useful tool for the prediction of preclinical abortions and multiple pregnancies.

경골 고평부 골절에서 단순 방사선 사진과 자기 공명 영상 사진에서 고평부 함몰 정도의 비교

서승우,임홍철,허창룡,문우남,박동,홍명표 대한골절학회 2002 대한골절학회지 Vol.15 No.2

First report of leaf spot on kiwifruit caused by <i>Phoma</i> sp. in Korea

Kwon, Y,Hong, SW,Kwack, Y-B,Kwak, Y-S Informa UK (TaylorFrancis) 2016 New Zealand journal of crop and horticultural scie Vol.44 No.3

<P>Small, dark brown leaf spots consistent with symptoms caused by Phoma sp. were observed on kiwifruit (Actinidia deliciosa cv. Hayward) at an orchard in Sacheon, South Korea. The causal agent was isolated from the spots and identified by morphological and molecular characteristics by sequencing the internal transcribed spacer region. To establish Koch's postulates, the pathogen was inoculated on to leaves in a pathogenicity test and reisolated from the developed lesions. Phoma sp. has been reported as a causal agent of kiwifruit leaf spot disease in New Zealand and Italy. However, this is the first report of leaf spot disease caused by Phoma sp. in Korea.</P>

임산부의 임신중 생활실태에 관한 관찰 ( IV )

홍성봉(SB Hong),박인서(IS Park),김승욱(SW Kim),곽현모(HM Kwak),박재현(JH Bark) 대한산부인과학회 1980 Obstetrics & Gynecology Science Vol.23 No.1

이미 보고한 바 서울시내 5개 의료기관을 순방한 5,000여명의 임부의 임신기간중의 일상 신체활동양상과 임신중의 직업관계, 약물복용 및 흡연실태 등을 조사한 바를 보고한 바이다. This paper is produced grom the data by interviewing exoectant mothers at 5 medical institutes in Seoul during the period of 20 months between February, 1975 and September, 1976, aiming primarily to elucidate possible association between induced abortion and the outcome of the subsequent pregnancies. Women attending antenatal clinics were interviewed twice before deliverisd and twice afterward. At the first contact 5,843 women were interviewed and 5,024 at the second between 24 and 32 weeks of their gestation periods. This paper is mostlt focussed on behaviors during their pregnancies and main results are summarized as following: 1.As shown in Table 1, 42.3 percent of women sit mostly, 47.5 percent half sit and half walk. the remainder, 10.2 percent mostly sit and walk in pregnancy. The proportion of women sitting mostly from extended family surpasses those from nuclear familt by 7.3 percent, which is probably due to the heavier household works among the former. Women sitting mostly are more often among those in twin pregnancies than singleton whereas those walking or standing mostly show more frequent occurrence of hypertension and edema, probably associated with their lower socio-economic backgrounds. The similarity is found with puerperal complication. 2.At the first interview about one-fourth of women is found to be gainfully em- ployed wgicgis reduced to one-sixth at the second interview. As illustrated in Table 2, collge graduate continues to wof=rk in 22.6 percent, middle or high school level 9.8 percent and primary scheel level 17.5 percent respectively. During the pregnancy, about 5 percent of women is enhahed in either heavy work or handling dust or chemicals, and appears to result in complications and malformations of their newborn more often than others.(see Table 3) 3.During the preganacy 27.4 percent of women experiences either surgical opera= tion, roentgen examination, inoculation or ultrasonic proxedure without an appreciable difference in outcome of preganacy and morbidity of the neqborns. 4.Women during pergnancy take medication for the therapeutic reasons in two -fifths. Multipara tends to take medicine less often compared to primigravida or women with experience of induced abortion in the past(See Table 4). 5.In Korea, smoker among expectant mothers is negligible(0.6%).