Logistics Research beyond 2000 : Theory, Method and Relevance

Cimen KARATAS-CETIN,Gul DENKTAS-SAKAR 한국해운물류학회 2013 The Asian journal of shipping and Logistics Vol.29 No.2

Logistics is a fertile field for scientific research constituting the application of various theories borrowed from the more established disciplines. There is an increasing need for the evaluation of the theory use in order to constitute a solid base for future development of the field. This paper seeks to elucidate the patterns of evolving logistics research since 2000 through the investigation of different theories and research methods employed. This study attempts to highlight the tension between the theories and the research methods employed in logistics discipline. It contributes to the current literature by providing an up-to-date outlook of the logistics research.

Effect of Hempseed (Cannabis sativa sp.) Inclusion to the Diet on Performance, Carcass and Antioxidative Activity in Japanese Quail (Coturnix coturnix japonica)

Konca, Yusuf,Cimen, Behzat,Yalcin, Hasan,Kaliber, Mahmut,Beyzi, Selma Buyukkilic Korean Society for Food Science of Animal Resource 2014 한국축산식품학회지 Vol.34 No.2

This study was conducted to determine the effects of hempseed (H) on performance, carcass traits, and antioxidant activity in Japanese quail (Coturnix coturnix japonica). A total of 192 quail with seven-days old were divided into four experimental groups with four replicates. The treatments were; i) Control diet (C, no hempseed); ii) 5% hempseed in diet (H5); iii) 10% hempseed in diet (H10); and iv) 20% hempseed in diet (H20). The body weight (BW) and feed intake (FI) of quail was determined at 7, 21 and 42 d of age. At 42 d of age four quail were slaughtered and the carcass and internal organ traits were determined. Malondialdehyde (MDA), catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), nitric oxide (NO) and total protein were determined in the blood serum end of the experiment. The BW of the groups were not significant at 7 and 21 d, however in the 20% hempseed group BW decreased at 42 d (p<0.05). The FI and feed conversion ratio were not significant among the treatment groups. The carcass, liver, intestine and heart weight and their percentage to carcass were significantly differ in treatment groups (p<0.05). The serum MDA and NO decreased in hempseed addition (p <0.001). The serum SOD, CAT and GSH-Px were increased by hempseed supplementation (p<0.001). In conclusion, hempseed supplementation to quail diets may not improve quail performance traits but increase antioxidant activity in blood.

Port Sustainability and Stakeholder Management in Supply Chains: A Framework on Resource Dependence Theory

Gul DENKTAS-SAKAR,Cimen KARATAS-CETIN 한국해운물류학회 2012 The Asian journal of shipping and Logistics Vol.28 No.3

Although sustainability is a topical concern in ports and the supply chain literature, the main focus of the academic research has been on the environmental dimension of sustainability rather than the social and economic dimensions. Since ports are indispensable nodes of supply chains involving many strategic stakeholders and activities interacting with each other,investigating the contribution of stakeholder relations on ports sustainability has emerged as a major concern. The main aim of this study is to provide a conceptual framework integrating the organizational relationships between supply chain and port stakeholders based on the theoretical background concerning the strategic management and the socially responsible marketing. This study attempts to identify the inuence of supply chain stakeholders on sustainability of ports by considering the propositions of interdependencies,power imbalances, and strategic options within resource dependence theory. While this paper can be regarded as a review of port sustainability literature,the uniqueness lies on the consideration of the concept from the basis of resource dependence theory. Conceptual framework of this study suggests that ports should adopt strategies as insertion, integration and dominance for the management of interdependencies through the adoption of strategic tools to enhance effective stakeholder relations management and port sustainability.

Effect of Hempseed (Cannabis sativa sp.) Inclusion to the Diet on Performance, Carcass and Antioxidative Activity in Japanese Quail (Coturnix coturnix japonica)

Yusuf Konca,Behzat Cimen,Hasan Yalcin,Mahmut Kaliber,Selma Buyukkilic Beyzi 한국축산식품학회 2014 한국축산식품학회지 Vol.34 No.2

This study was conducted to determine the effects of hempseed (H) on performance, carcass traits, and antioxidant activity in Japanese quail (Coturnix coturnix japonica). A total of 192 quail with seven-days old were divided into four experimental groups with four replicates. The treatments were; i) Control diet (C, no hempseed); ii) 5% hempseed in diet (H5); iii) 10% hempseed in diet (H10); and iv) 20% hempseed in diet (H20). The body weight (BW) and feed intake (FI) of quail wasdetermined at 7, 21 and 42 d of age. At 42 d of age four quail were slaughtered and the carcass and internal organ traits weredetermined. Malondialdehyde (MDA), catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), nit-ric oxide (NO) and total protein were determined in the blood serum end of the experiment. The BW of the groups were notsignificant at 7 and 21 d, however in the 20% hempseed group BW decreased at 42 d (p<0.05). The FI and feed conversionratio were not significant among the treatment groups. The carcass, liver, intestine and heart weight and their percentage tocarcass were significantly differ in treatment groups (p<0.05). The serum MDA and NO decreased in hempseed addition (p<0.001). The serum SOD, CAT and GSH-Px were increased by hempseed supplementation (p<0.001). In conclusion, hemp-seed supplementation to quail diets may not improve quail performance traits but increase antioxidant activity in blood.

Depressive Temperament in Relatives of Patients with Schizophrenia Is Associated with Suicidality in Patients with Schizophrenia

Esra Yazici,Zerrin Cimen,Ipen Ilknur Unlu Akyollu,Ahmet Bulent Yazici,Betul Aslan Turkmen,Atila Erol 대한정신약물학회 2018 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.16 No.3

Objective: Suicide is a major cause of death in patients with schizophrenia; thus, predicting and preventing suicide in patients with schizophrenia is examined in various studies. Affective temperaments which are accepted as precursors of mood disorders may be an important factor in predicting suicidality. This study investigated the relationship between affective temperaments of relatives of schizophrenia patients and suicidal thoughts and other clinical correlates of patients with schizophrenia. Methods: Patients with schizophrenia and their first degree relatives are included to the study. All of the participants were evaluated with Structured Clinical Interview for DSM-IV axis I disorders and relatives with active psychiatric diagnosis were excluded. Positive and Negative Symptom Scale, Clinical Global Impression Scale, Turkish version of cognitive assessment interview were administered congruently to the patients. Relatives of the patients were evaluated with Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Auto-questionnaire. Results: Depressive temperament scores of relatives of schizophrenic patients who had suicidal thoughts were higher than the scores of the relatives of the patients who did not have suicidal thoughts. Depressive temperament also predicted number of suicide attempts in regression analysis. Number of suicide attempts was also related with number of hospitalization and functionality of the patient. Conclusion: Suicidality in schizophrenia is related with relatives’ affective temperaments and patients’ own positive symptom scores. The relationship between suicidal thoughts and depressive temperament is high lightened in this study

Supervisory Controller Design to Enforce Reversibility and Liveness in Colored Petri Nets

Aybin Aybar,Mustafa Cimen 대한전기학회 2007 International Journal of Control, Automation, and Vol.5 No.4

Colored Petri net model which is a model of discrete event systems is considered in this work. A supervisory controller which enforces reversibility and liveness simultaneously is presented. Furthermore, the algorithms, written by pseudo-code, are presented for the supervisory controller design. A program is developed to implement these algorithms.

Effect of etoricoxib on experimental oxidative testicular ischemia–reperfusion damage in rats induced with torsion– detorsion

Turgut Yapanoglu,Fatih Ozkaya,Ali Haydar Yilmaz,Renad Mammadov,Ferda Keskin Cimen,Erkan Hirik,Durdu Altuner 대한약리학회 2017 The Korean Journal of Physiology & Pharmacology Vol.21 No.5

Etoricoxib features antioxidant and anti-inflammatory properties concomitantly, suggesting that it may be beneficial in testicular ischemia reperfusion (I/R) damage. Our aim is to investigate the effects of etoricoxib on testicular I/R damage induced with torsion-detorsion (TD). The etoricoxib + torsion-detorsion (ETD) groups of animals were given etoricoxib in 50 and 100 mg/kg of body weight (ETD- 50 and ETD-100), while the testes torsion-detorsion (TTD) and sham operation rat group (SOG) animals were given single oral doses of distilled water as a solvent. TTD, ETD-50 and ETD-100 groups were subjected to 720o degrees torsion for four hours, and detorsion for four hours. The SOG group was not subjected to this procedure. Biochemical, gene expression and histopathological analyses were carried out on the testicular tissues. The levels of malondialdehyde (MDA), myeloperoxidase (MPO), interleukin-1 beta (IL-1β) and tumor necrosis factor alpha (TNF-α) were significantly higher, and the levels of total glutathione (tGSH) and glutathione reductase (GSHRd) were significantly lower in the TTD group, compared to the ETD-50, ETD-100 and SOG groups. Etoricoxib at a dose of 100 mg/kg better prevented I/R damage than the 50 mg/kg dose. Etoricoxib may be useful in clinical practice in the reduction of I/ R damage on testes caused by torsion-detorsion.

Effect of Hippophae rhamnoides Extract on Oxidative Oropharyngeal Mucosal Damage Induced in Rats Using Methotrexate

Ertugrul Erhan,Suat Terzi,Metin Celiker,Oguzhan Yarali,Murat Cankaya,Ferda Keskin Cimen,Ismail Malkoc,Bahadir Suleyman 대한이비인후과학회 2017 Clinical and Experimental Otorhinolaryngology Vol.10 No.2

Objectives. The objective of this study is to investigate and evaluate the effect of Hippophae rhamnoides extract (HRE) on oropharyngeal mucositis induced in rats with methotrexate (MTX) through biochemical, gene expression, and histopathological examinations. Methods. Experimental animals were divided into a healthy group (HG), a HRE+MTX (HREM) group, HRE group (HREG), and a control group that received MTX (MTXG). The HREM and HREG groups of rats was administered 50 mg/kg HRE, while the MTXG and HG groups were given an equal volume distilled water with gavage. Then, the HREM and MTXG rat groups were given oral MTX at a dose of 5 mg/kg 1 hour after HRE and distilled water was administered. This procedure was repeated for 1 month. At the end of this period, all of the animals were sacrificed with a high dose of anesthesia. Then, the amounts of malondialdehyde (MDA) and total glutathione (tGSH) were determined in the removed oropharyngeal tissues. Interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) gene expressions were measured, and all the tissues were studied histopathologically. Results. The amount of MDA was significantly increased in the MTXG group compared to the HREM, HREG, and HG groups (P<0.001). MTX significantly decreased the amount of tGSH in the MTXG group compared to the HREM, HREG, and HG groups (P<0.001). In this study, there were no visible ulcers in the animal group in which the levels of MDA, IL-1β, and TNF-α were high and the level of tGSH was low. However, histopathologic examination revealed mucin pools in wide areas due to ruptured oropharynx glands, and proliferated, dilated, and congested blood vessels and dilated ductal structures in some areas. Conclusion. HRE protected oropharyngeal oxidative damage induced by MTX. As an inexpensive and natural product, HRE has important advantages in the prevention of oropharyngeal damage induced by MTX.

Effect of etoricoxib on experimental oxidative testicular ischemia-reperfusion damage in rats induced with torsion-detorsion

Yapanoglu, Turgut,Ozkaya, Fatih,Yilmaz, Ali Haydar,Mammadov, Renad,Cimen, Ferda Keskin,Hirik, Erkan,Altuner, Durdu The Korean Society of Pharmacology 2017 The Korean Journal of Physiology & Pharmacology Vol.21 No.5

Etoricoxib features antioxidant and anti-inflammatory properties concomitantly, suggesting that it may be beneficial in testicular ischemia reperfusion (I/R) damage. Our aim is to investigate the effects of etoricoxib on testicular I/R damage induced with torsion-detorsion (TD). The etoricoxib + torsion-detorsion (ETD) groups of animals were given etoricoxib in 50 and 100 mg/kg of body weight (ETD-50 and ETD-100), while the testes torsion-detorsion (TTD) and sham operation rat group (SOG) animals were given single oral doses of distilled water as a solvent. TTD, ETD-50 and ETD-100 groups were subjected to $720^{\circ}$ degrees torsion for four hours, and detorsion for four hours. The SOG group was not subjected to this procedure. Biochemical, gene expression and histopathological analyses were carried out on the testicular tissues. The levels of malondialdehyde (MDA), myeloperoxidase (MPO), interleukin-1 beta ($IL-1{\beta}$) and tumor necrosis factor alpha ($TNF-{\alpha}$) were significantly higher, and the levels of total glutathione (tGSH) and glutathione reductase (GSHRd) were significantly lower in the TTD group, compared to the ETD-50, ETD-100 and SOG groups. Etoricoxib at a dose of 100 mg/kg better prevented I/R damage than the 50 mg/kg dose. Etoricoxib may be useful in clinical practice in the reduction of I/R damage on testes caused by torsion-detorsion.

Effect of lutein on methotrexate-induced oxidative lung damage in rats: a biochemical and histopathological assessment

Renad Mammadov,Bahadir Suleyman,Selcuk Akturan,Ferda Keskin Cimen,Nezahat Kurt,Zeynep Suleyman,İsmail Malkoc 대한내과학회 2019 The Korean Journal of Internal Medicine Vol.34 No.6

Background/Aims: This study aimed to investigate the effect of lutein on methotrexate (MTX)-induced pulmonary toxicity in rats biochemically and histopathologically. Methods: The rats in the MTX + lutein (MTXL, n = 6) group were given 1 mg/kg of lutein orally. A 0.9% NaCl solution was administered orally to the MTX (n = 6) group and the healthy group (HG, n = 6). One hour later, a single 20 mg/kg dose of MTX was injected intraperitoneally in the MTXL and MTX. Lutein or 0.9% NaCl solution was administered once a day for 5 days. At the end of this period, malondialdehyde (MDA), myeloperoxidase (MPO), total glutathione (tGSH), interleukin 1 beta (IL-1β), and tumor necrosis factor alpha (TNF-α) were measured in the lung tissues from the animals euthanized with 50 mg/kg thiopental sodium anesthesia. Subsequently, histopathological examinations were performed. Results: The levels of MDA, MPO, IL-1β, and TNF-α in the lung tissue of the MTX were significantly higher than those of the MTXL and HG groups (p < 0.0001), and the amount of tGSH was lower. The histopathological findings in the MTX group, in which the oxidants and cytokines were higher, were more severe. Conclusions: Lutein prevented the MTX-induced oxidative lung damage biochemically and histopathologically. This result indicates that lutein may be useful in the treatment of MTX-induced lung damage.