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차윤엽 ( Yun Yeop Cha ),고연석 ( Youn Seok Ko ),이정한 ( Jung Han Lee ),정원석 ( Won Suk Chung ),신병철 ( Byung Cheul Shin ),전찬용 ( Chan Yong Jeon ),고호연 ( Ho Yeon Go ),선승호 ( Seong Ho Sun ),장보형 ( Bo Hyoung Jang ),송윤경 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.2
Objectives : The purpose of this study is to explore the trends of Korean medical study on stress in the industrial worker. Methods : We received numbers of the studies about stress in the industrial worker from 6 Korean web databases, using key words such as ‘Industry AND Stress’, ‘Oriental medicine AND Stress’, ‘Worker AND Stress’, ‘Workplace AND Stress’. We received 12 research papers and they were analyzed and the journals, the authors, the contents of 3 classification of those research papers. Results : Among them, we had 6 reviews of Dept. of preventive medicine and Dept. of third medicine, college of Korean Medicine, Won-kwang University, and the rest of them were 6 reviews. We had 4 reviews of Korean Journal of Oriental Preventive Medical Society, 2 reviews of the Journal of Traditional Korean Medicine, 2 reviews of Journal of Oriental Neuropsychiatry and so on. According to the contents of reviews, we had 7 reviews of correlation of industrial worker and stress, 4 reviews of cause on the industrial worker’s stress and 1 case report. Conclusions : We reviewed the trends of Korean medical study on stress in the industrial worker. The stress in the industrial workers were related with the type of occupation, social psychology, drinking, smoking, the satisfaction of job, the harmony of organization.And we knew that the musculoskeletal pain was related to the industrial worker’s stress. In the future, abundant case studies, follow-up trials and RCTs should be done about the industrial worker’s stress.
Determinants of Basal Collaterals in Moyamoya Disease: Clinical and Genetic Factors
Chung, Jong-Won,Kim, Suk Jae,Bang, Oh Young,Kim, Kun Ha,Ki, Chang-Seok,Jeon, Pyeong,Yeon, Je Young,Kim, Jong-Soo,Hong, Seung Chyul,Shin, Hyung Jin S.Karger 2016 European neurology Vol.75 No.3
<P>Background/Aims: To enable the diagnosis of moyamoya disease (MMD), detection of distal internal carotid artery stenosis and hazy network of basal collaterals (BCs) are required. This study aimed at evaluating the factors that could determine the degree of BCs in patients with angiographically confirmed MMD. Methods: We analyzed 146 consecutive patients with MMD (age 26.2 +/- 19.6, range 1-75). The degree of BCs (%) was measured based on conventional angiography. Factors associated with the degree of BCs, including clinico-radiological and genetic factors (p.Arg4810Lys variant), were analyzed. Results:The degree of BCs varied among MMD patients and significantly decreased with an increase in the age of diagnosis of MMD (coefficient -1.55; p < 0.001). Although the degree of BC development depends on the MMD stage (Suzuki stage), it is less prominent in adult-onset (>18 years) MMD compared to childhood MMD. The presence of p.Arg4810Lys variant, types of MMD (bilateral vs. uni-lateral) and stroke (ischemic, hemorrhagic, or asymptomatic), shrinkage (outer diameter) of intracranial vessels, external carotid collateral status, and cortical neovascularization were not associated with the degree of BCs. Conclusion: Although prominent BCs are required for diagnosis of MMD, BCs are decreased with aging, suggesting that angiogenic capacity is altered in adult onset MMD compared to childhood MMD. (C) 2016 S. Karger AG, Basel</P>
( Suk Hyeon Jeong ),( Su Young Kim ),( Hyun Lee ),( Jun Soo Ham ),( Keum Bit Hwang ),( Subin Hwang ),( Sun Hye Shin ),( Myung Jin Chung ),( Seung Heon Lee ),( Sung Jae Shin ),( Won Jung Koh ) 대한결핵 및 호흡기학회 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4
This is a report of the first South Korean case of a lung disease caused by Mycobacterium simiae. The patient was a previously healthy 52-year-old female. All serial isolates were identified as M. simiae by multi-locus sequencing analysis, based on hsp65, rpoB, 16S-23S rRNA internal transcribed spacer, and 16S rRNA fragments. A chest radiography revealed deterioration, and the follow-up sputum cultures were persistently positive, despite combination antibiotic treatment, including azithromycin, ethambutol, and rifampin. To the best of our knowledge, this is the first confirmed case of a lung disease caused by M. simiae in South Korea.
Relationship between Helicobacter Pylori Infection and Gastroduodenal Diseases
Chung, In Sik,Chae, Hiun Suk,Yang, Jin Mo,Choi, Myung Kyu,Chung, Kyu Won,Sun, Hee Sik,Kim, Boo Sung CATHOLIC MEDICAL CENTER 1992 Bulletin of the Clinical Research Institute Vol.20 No.1
To investigate the relationship between Helicobacter pylori infection and gastroduodenal diseases, we examined the presence of H pylori in 1,100 endoscopic biopsy specimens from esophaguss, gastric mucosa and duodenal bulb with silver stain and examined also the grades of inflammation histologically in patients with gastroduodenal diseases. H pylori was detected on the gastric mucosa in 64.0% of patients with chronic gastritis, 79.3% of erosive gastritis, 58.5% of gastric ulcer, 86.5% of duodenal ulcer, 87.9% of combined ulcer (gastric and duodenal), 24.4% of gastric cancer, and 63.5% of endoscopically normal subjects. H pylori was found on duodenal bulb in 13.6% of all cases studied, 36.4% of patients with duodenal ulcer, 7.4% of erosive gastritis. The mucosa of duodenal bulb in these patients had gastric metaplasia. There was no H pylori in the epithelium of esophagus except for one case of Barrett’s esophagus. H pylori was not found in the area of intestinal metaplasia, at lesions of adenoma, or intestinal type gastric cancer. H pylori was observed more frequently in fundal mucosa (68.7%) than in antral mucosa (59.1%) in Korea. It was also shown that H pylori was more frequently found in antrum in young patients and in fundus in aged patients. Grades of inflammation were closely correlated with the grades of H pylori infection in the gastric mucosa. Severity of inflammation in fundic mucosa was milder than that of antral mucosa with same grade of H pylori infection. In conclusion, existence of H pylori is limited on gastric type mucosa and thought to be related with pathogenesis of chronic active gastritis and duodenal ulcer formation. In addition, H pylroi is more frequently found on fundic mucosa than on antral mucosa among Koreans. No H pylori is detected at the lesion of adenoma, nor at the lesion of intestinal type of gastric cancer.
A New Garden Pea Cultivar "Daehyup 2" with Large Seed Size and High Sugar Contents
Won Young Han,In Youl Baek,Sang Ouk Shin,Hyun Tae Kim,Jong Min Ko,Nam Suk Kang,Ki Won Oh,Chan Sik Jung,Doo Chull Shin,Sung Taek Kang,Myung Gun Chung,Keum Yong Park,Duck Yong Suh 한국육종학회 2007 한국육종학회지 Vol.39 No.3
A new garden pea cultivar, Daehyup 2, was developed at the Yeongnam Agricultural Research Institute (YARI) in 2006. It was selected from the cross between Olwandu and Sachulwandu in 1996. The preliminary, advanced, and regional yield trials for evaluation and selection of this cultivar were carried out from 2003 to 2006. It has white flower, yellow cotyledon, absent or very weakly curved pod shape and yellow seed color. It was resistant to virus and powdery mildew disease. The 100 green seed weight of Daehyup 2 was 65.5 g, which was 8.9 g heavier than check cultivar. The sucrose and total sugar contents of fresh pod of Daehyup 2 were 11.1% and 12.5%, respectively, which were 3.2% and 4.3% higher than those of Sachulwandu. The fresh pod yield of Daehyup 2 was similar to that of Sachulwandu with 12.16 ton per hectare in the regional yield trials carried out in three locations of Korea from 2005 to 2006.
( Won Jai Jung ),( Byung Hoon Park ),( Kyung Soo Chung ),( Song Yee Kim ),( Eun Young Kim ),( Ji Ye Jung ),( Young Ae Kang ),( Young Sam Kim ),( Se Kyu Kim ),( Joon Chang ),( Moo Suk Park ) 대한결핵 및 호흡기학회 2013 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.116 No.-
Background: Plasma glucagon in sepsis has scarcely studied. We tried to identify whether glucagon levels were associated with disease severity and mortality in patients with severe sepsis or septic shock. Methods: We evaluated patients with severe sepsis or septic shock admitted to ICU of the university-affiliated hospital in Korea. Plasma levels of glucagon were measured in a total 112 patients (57 survivors and 55 non-survivors) with severe sepsis or septic shock. Results: Compared with the survivors, patients who died in 28 days had significantly higher levels of glucagon on day 0 (admission day), 1, 3, and 7. Glucagon levels were correlated with severity scores (SOFA and APACHE-II). Multivariate analysis identified glucagon levels, presence of septic shock as independent predictors of the overall 28-day mortality rate. Receiver operating characteristic analysis showed that the area under curve of glucagon levels to predict 28-day survival was 0.63 (95% CI=0.52-0.73; P=0.021) as similar as APACHE II. Conclusions: Glucagon levels are related to poor prognosis in patients with severe sepsis.Background: Plasma glucagon in sepsis has scarcely studied. We tried to identify whether glucagon levels were associated with disease severity and mortality in patients with severe sepsis or septic shock. Methods: We evaluated patients with severe sepsis or septic shock admitted to ICU of the university-affiliated hospital in Korea. Plasma levels of glucagon were measured in a total 112 patients (57 survivors and 55 non-survivors) with severe sepsis or septic shock. Results: Compared with the survivors, patients who died in 28 days had significantly higher levels of glucagon on day 0 (admission day), 1, 3, and 7. Glucagon levels were correlated with severity scores (SOFA and APACHE-II). Multivariate analysis identified glucagon levels, presence of septic shock as independent predictors of the overall 28-day mortality rate. Receiver operating characteristic analysis showed that the area under curve of glucagon levels to predict 28-day survival was 0.63 (95% CI=0.52-0.73; P=0.021) as similar as APACHE II. Conclusions: Glucagon levels are related to poor prognosis in patients with severe sepsis.Background: Plasma glucagon in sepsis has scarcely studied. We tried to identify whether glucagon levels were associated with disease severity and mortality in patients with severe sepsis or septic shock. Methods: We evaluated patients with severe sepsis or septic shock admitted to ICU of the university-affiliated hospital in Korea. Plasma levels of glucagon were measured in a total 112 patients (57 survivors and 55 non-survivors) with severe sepsis or septic shock. Results: Compared with the survivors, patients who died in 28 days had significantly higher levels of glucagon on day 0 (admission day), 1, 3, and 7. Glucagon levels were correlated with severity scores (SOFA and APACHE-II). Multivariate analysis identified glucagon levels, presence of septic shock as independent predictors of the overall 28-day mortality rate. Receiver operating characteristic analysis showed that the area under curve of glucagon levels to predict 28-day survival was 0.63 (95% CI=0.52-0.73; P=0.021) as similar as APACHE II. Conclusions: Glucagon levels are related to poor prognosis in patients with severe sepsis.
Chung, Hak-Jae,Kim, Bong-Ki,Kim, Jong-Mu,Lee, Hyun-Gi,Han, Joo-Hee,Kim, Nam-Hyung,Park, Jin-Ki,Seong, Hwan-Hoo,Yang, Boh-Suk,Chang, Won-Kyong,Ko, Yeoung-Gyu The Korean Society of Animal Reproduction 2006 Reproductive & developmental biology Vol.30 No.4
Transforming growth $factor-{\beta}\;(TGF-{\beta})$ has been shown to have a positive effect on in vitro fertilization (IVF) and has been reported to stimulate meiosis at follicular level in variety of species. The study was designed to determine the expression patterns of $TGF-{\beta}1,\;TGF-{\beta}$ receptors type I, II and Smads gene in bovine oocytes and embryos. $TGF-{\beta}1$ and their receptors were observed in the unfertilized oocytes. $TGF-{\beta}1$ and type II receptor were not expressed at the blastocyst stage, however, only type I receptor was exclusively observed at the same stage. The blastocyst stage, in particular, showed high levels of mRNA expression patterns containing a $TGF-{\beta}1$ type I receptor. The mRNA expression pattern of Smad 2 at all stages of embryonic development was similar in all respect with $TGF-{\beta}1$ type I receptor. On the contrary, Smad 3 and 4 were expressed with high and low level mRNA at the blastocyst stage. In conclusion. it is suggested that $TGF-{\beta}1$ signaling may be regarded as an important entity during the preimplantation embryo development.