국내 한방병원의 알레르기 비염 환자 현황에 대한 탐색적 연구 - 3개 대학한방병원의 전자의무기록 자료를 중심으로

장보형,최인화,김규석,김희택,김경준,김민희,박정수,고성규,Jang, Bo-Hyoung,Choi, In-Hwa,Kim, Kyu-Seok,Kim, Hee-Taek,Kim, Kyung-Jun,Kim, Min-Hee,Park, Jeong-Su,Ko, Seoung-Gyu 대한한방안이비인후피부과학회 2014 한방안이비인후피부과학회지 Vol.27 No.1

Objective : To study current status on characteristics of allergic rhinitis patients by using the electronic medical record (EMR) data and to explore the feasibility of clinical studies using the EMR data in three different Korean medical hospitals. Methods : We studied allergic rhinitis patients who visited the department of ophthalmology, otolaryngology and dermatology in the three different Korean hospitals from January 1, 2012 to December 31, 2012. We retrospectively collected medical history and characteristics of study subjects using data of EMR. Results : In hospital A, we were able to collect data of 18 years of age or older. In hospital C, we could only collect data after July 1, 2012. Therefore, each hospital's data had different settings in measuring them. Men and women were accounted for similar percentage, and teens were the highest in the age group. J30.4, unspecified allergic rhinitis, was the highest in diagnosis of the allergic rhinitis. Most of the patients have received acupuncture treatments. Moreover, 74.6 percent of the total patients were prescribed with Chinese medicine. Conclusions : Based on this exploratory study, further studies were needed on clinical studies using data of systematic EMR.

내시경 검사를 시행한 소화불량 환자 100례에 대한 사상의학적 분포 연구

장보형,노임선,김은곤,권혁성,권오섭,이정희,Jang, Bo-Hyoung,Ro, Im-Sun,Kim, Eun-Gon,Kweon, Hyug-Sung,Kweon, O-Seob,Lee, Jung-Hee 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.4

Objective : The purpose of this study is to determine a distribution of sasang constitution among dyspepsia patients, and to weigh their symptoms score. Methods : We surveyed symptoms of dyspepsia and QSCCII in one hundred dyspepsia patients who had undergone upper gastrointestinal endoscopy. Results : In distribution of sasang constitution in total dyspepsia patients group and distribution according to the result of endoscopy, ratio and symptoms score of So-Eum-tn were higher than the others. However the differences were not statistically significant. According to symptoms score by age, symptoms score of Tae-Eum-In in patients above 35 years old group was higher than the others. In patients group under 35 years old, symptoms score of So- Yang-In is higher than the others. However in neither group was this statistically significant.

초등학교 어린이의 허약상태 및 성장부진에 대(對)한 보고(報告)

장보형,권미원,왕향란,Jang, Bo-Hyoung,Kwon, Mi-Won,Wang, Hyang-Lan 대한한방소아과학회 2005 대한한방소아과학회지 Vol.19 No.2

Objective : As the meaning of collective medical examination, the purpose of this study is to investigate distribution of weak children by measurement according to the five group of weakness (Lung, Heart, Pancreas, Liver, Kidney), and the relationship between the five group of weakness and the Growth failure on primary school children. Methods : This study is composed of 1078 children who attend A primary school in ${\bigcirc}{\bigcirc}$ city. They are divided into 6 groups by grade and for the purpose of effective comparison, The five weak symptoms are studied to determine the association with growth stature among children and we standardize the weak children's height into percent according to age. Results: When each weak children controled grade, sex, body-weight, existence or nonexistence of personal history, physical exercise so on, relatively group of weakness for kidney is statistically less then opposite group and the rest of the people statistically have no significant difference. Conclusions: From the above result, it is suggested that the statistical relationship between the weakness for kidney and growth(p<0.001). It looks forward to have contributed to collective medical examination and children's health care by oriental medical treatment.

통증완화를 위해 비파엽 찜질을 병행한 암환자 6례에 대한 증례보고

이정희,장보형,권혁성,권오섭,Lee Jung-Hee,Jang Bo-Hyoung,Kweon Hyug-Sung,Kweon O-Seob 대한한방내과학회 2003 大韓韓方內科學會誌 Vol.24 No.4

Objective: The purpose of this study is to see whether pain in cancer patients is decreased by Eriobotryae Folium Fomentation. Methods: We examined the change in pain among six cancer patients, prescribing Eriobotryae Folium Fomentation. As for evaluating methods, we used the case history of pain, the direct evaluation of pain, the indirect evaluation of pain. The direct evaluation of pain is subdivided by the language expression, the non-language expression, and Visual analog scale(VAS). The indirect evaluation of pain is subdivided by the condition of walking, mood and the condition of sleep. Results: After two weeks, any remarkable pain decrease is not observed in both of the direct evaluation and indirect evaluation.

요통 처방을 통하여 본 한약제제 효능 개정의 필요성

장수빈,고호연,장보형,송윤경,신용철,고성규,Jang, Soobin,Go, Ho-Yeon,Jang, Bo-Hyoung,Song, Yun-Kyung,Shin, Yong-Cheol,Ko, Seong-Gyu 대한예방한의학회 2015 대한예방한의학회지 Vol.19 No.1

Objective : There are many documents that explain efficacy of herbal medicine products (HMP), however, explanations on efficacy are not consistent with the clinical use. The objective of this study is to identify the differences between herbal medicines used in clinics and Korean Medicine literatures. The disease was restricted in low back pain (LBP). Method : In order to investigate HMP for the treatment of LBP, we selected five Korean medical documents as reference and searched for key words related to LBP. Five databases were Information on Herbal prescription published by Ministry of Food and Drug Safety, 56 Herbal Medicines covered with Health Insurance, Guideline for prescribing herbal medicines announced by Ministry Health & Welfare, Explanation on Herbal Medicines published by Korean Pharmaceutical Association, website of Korea Pharmaceutical Information Center (http://www.health.kr/). The keywords were 'low back pain', 'lumbar', 'pain', 'myalgia', 'neuralgia', 'arthralgia', 'arthroneuralgia', and 'sciatica'. We also utilized the result of retrospective cross-sectional study in five university hospitals to investigate HMP used in practice for LBP. Results : From five databases, the number of searched HMP was 25, 12, 40, 12 and 38 respectively and 83 remained after removing duplications. There were 43 kinds of HMP used in clinical practice and only 20 (46.51 %) were included in one or more databases. Conclusion : This study suggests the necessity for reorganizing efficacy of herbal medicine. Standardizing explanation on herbal medicine should reflect the clinical conditions in further study.

암 환자 대상 한의약 임상시험에서 변증 활용에 대한 분석

전천후,박선주,장보형,신용철,고성규,Cheon, Chunhoo,Park, Sunju,Jang, Bo-Hyoung,Shin, Yongcheol,Ko, Seong-Gyu 대한예방한의학회 2015 대한예방한의학회지 Vol.19 No.1

Objective : The aim of this study is to investigate the features of clinical trial which used symptom differentiation on cancer patients Method : Electronic databases including Ovid-Medline, Ovid-EMBASE, and Cochrane library were searched. Search terms incorporating the concepts of cancer, herbal medicine, clinical trial were used. Articles described using symptom differentiation in methods were selected. Results : Twelve studies used symptom differentiation for prescribing herbal medicine to cancer patients. A total of 36 symptom differentiation were used. The kind of the herbal medicines was varied as much as the kind of symptom differentiation. Conclusion : Most of herbal medicines used for cancer patients focused on quality of life or adverse events rather than tumor size. Symptom differentiation and herbal medicine used in selected studies were too diverse to categorize. To use standardized symptom differentiation, symptom differentiation instrument should be developed and reliability test and validity test are needed.

자운고의 한의사 처방 현황에 대한 웹기반 설문조사

강민서,김민희,장보형,최인화,Kang, Min-Seo,Kim, Min-Hee,Jang, Bo-Hyoung,Choi, In Hwa 대한한방안이비인후피부과학회 2018 한방안이비인후피부과학회지 Vol.31 No.2

Objectives : The purpose of this survey is to examine Korean medical doctor's prescription status of Jaungo. Methods : The questionnaire was distributed via e-mail to Korean medical doctors who were registered in the association of Korean medicine from December 26th 2017 to February 5th 2018. We screened out respondents who didn't meet screening criteria. Results : Total 325 respondents completed answers, and the computerized data were analyzed. 74.7% of respondents were provided Jaungo from outside (extramural herbal dispensaries, pharmaceutical company). Almost all of the respondents (98.2%) were prescribing Jaungo in the form of ointment, and the cream container was the most commonly used container. In chief Indications of Jaungo were skin dryness (83.1%), pruritus (67.7%), burns (64.0%), and atopic dermatitis (60.9%). More than 60% of the respondents were prescribing Jaungo without additional herbs or additives. Most of patients were educated to apply Jaungo thinly to the affected area once or twice a day or frequently. Reason for dissatisfaction about Jaungo of patient were due to staining clothes (59.1%), offensive smell (44.0%), and poor texture (26.5%). Conclusions : Jaungo is a topical herbal agent frequently used in the Korean medicine. This is the first survey figure out current status of topical herbal agent in Korean medical doctors. The result of this study would contribute to progressing treatment method using topical herbal agent.

성요한초제제 임상시험 고찰을 통한 한약기원 항우울제 임상시험 방법론 연구

정희,이지형,장보형,고성규,Jung, Hee,Lee, Ji-Hyung,Jang, Bo-Hyoung,Ko, Seong-Gyu 대한한방내과학회 2007 大韓韓方內科學會誌 Vol.28 No.2

Objectives : This study was undertaken to learn what should be considered in a good clinical trial investigating a herbal medicine as an antidepressant. Methods : Five well-designed clinical trials published from 2000 to 2006 investigating SJWE in depressive disorder were selected. The trials were reviewed and compared in terms of methodology such as trial design, patient selection, efficacy & safety evaluation, and so on. On the basis of this review of the trials and the regulations and guidelines of KFDA, we suggest some points to be considered for a good clinical trial of a herb for depression. Results : Although every trial had its own unique design, procedure, objectives and so on, all trials used randomizing and double blinding methods. If there is no ethical problem, a placebo-controlled design should be considered in a herbal antidepressant clinical trial for depression. Conclusions : Some points to be considered in an optimal & good clinical trial for an antidepressive herbal medicine were suggested as follows: 1) randomizing and double blinding manner is essential, 2) if there is no ethical problem, placebo control design should be considered, 3) the trial period should be 6 weeks, 4) out-patients will be recruited as subjects, 5) investigators will be well-trained psychiatrists or medical doctors, 6) the number of subjects should be calculated by statistical methods, 7) subjects should be diagnosed by DSM-IV criteria, 8) subjects who have current risk of committing suicide should be excluded, etc.

해외논문고찰을 통한 천식 및 기침${\cdot}$가래 치료제의 유효성 평가지표 개발연구

오미현,이지형,장보형,정승기,선승호,고호연,전찬용,박종형,고성규,Oh, Mi-Hyune,Lee, Ji-Hyung,Jang, Bo-Hyoung,Jung, Sung-Ki,Sun, Seung-Ho,Ko, Ho-Yeon,Jun, Chan-Yong,Park, Jong-Hyeong,Ko, Seong-Gyu 대한한방내과학회 2007 大韓韓方內科學會誌 Vol.28 No.3

Objectives : The purpose of this study was to develop outcome indicators in clinical trials of herbal drugs effective for asthma. cough and sputum. To accomplish the objective, this study collected outcome indicators developed and used according to conventional medical concepts. Methods : Our research group reviewed SCI papers concerned with developing outcome indicators to evaluate amelioration of asthma, cough and sputum. We also reviewed clinical trials of herbal drugs effective for them. Results : To evaluate asthma, objective as well as subjective methods were chosen according to the purpose of each trial. Objective methods were PEF, FEVl, serum IgE, peripheral eosinophil counts, and so on. Subjective methods were symptom scores, symptom diaries, quality of life measures, etc. To evaluate cough and sputum, objective and subjective methods were also chosen. Objective methods were tussigenic challenges, sputum induction and computerized methodology, and subjective methods were similar to the methodology evaluating asthmatic symptoms. Conclusions : It is desirable for a clinical trial evaluating herbal drugs for asthma, cough and sputum to use objective and subjective outcome indicators together. However, biological outcome indicators, a kind of objective methods, can not be chosen as the purpose of trial. Valid and reliable subjective outcome indicators are needed to develop good clinical trials of herbal drugs effective for asthma, cough and sputum.

요골신경마비(撓骨神經痲痺) 치험(治驗) 1례(例)

이광호,김태우,장보형,권오섭,류충렬,조명래,문경숙,Lee, Kwang-Ho,Kim, Tae-Woo,Jang, Bo-Hyoung,Kweon, O-Seop,Ryu, Chung-Ryeul,Cho, Myung-Rae,Mun, Kyung-Suk 대한약침학회 2004 Journal of pharmacopuncture Vol.7 No.3

Objective : The purpose of this study is to report the patient with radial nerve palsy, who improved by oriental medical treatment. Methods : The patient was managed by Cathami Flos aqua-acupuncture, Dong-Qi acupuncture treatment, Comman acupuncture treatment and Herbal medicine. We took pictures of patient's wrist and checked the power of muscles. And we checked the numbness of thumb that was patient's subjective sensation. Results : After 2 weeks-treatment, the movement and power of wrist was restored to nearly normal range, also the numbness of thumb was removed. Combined oriental medical treatment can treat radial nerve palsy earlier than the other methods. Conclusions : The results suggest that combination of Cathami Flos aqua-acupuncture, Dong-Qi acupuncture treatment, Comman acupuncture treatment and Herbal medicine is good method for treatments of radial nerve palsy. But further studies are required to concretely prove the effectiveness of this method for treating radial nerve palsy.