다시마 분말을 첨가한 김부각의 품질 특성

최현미 ( Hyeon Mee Choi ),심창환 ( Chang Hwan Sim ),신태선 ( Tai Sun Shin ),빙동주 ( Dong Joo Bing ),전순실 ( Soon Sil Chun ) 한국식품영양학회 2011 韓國食品營養學會誌 Vol.24 No.3

In this study, certain quality characteristics of kimbugak samples prepared with 2 different puffing methods, microwave oven and frying, and containing different levels of sea tangle powder(0, 2, 4, and 6%), were examined according to mineral content, moisture content, color values, photographic images, hardness and sensory evaluations. The mineral contents of Porphyra yezoensis were: K, 2,612.400 ㎎; Ca, 116.970 ㎎; Na, 486.099 ㎎; Mg, 297.800 ㎎; Fe, 9.636 ㎎; Mn, 1.614 ㎎; and Cu, 0.973 ㎎. And those of the sea tangle powder were: K, 5,115.000 ㎎; Na, 1,848.931 ㎎; Ca, 763.030 ㎎; Mg, 525.700 ㎎; Fe, 15.125 ㎎; Zn, 4.639 ㎎; and Mn, 0.146 ㎎. Moisture content was not significantly different among the samples of kimbugak puffed by the microwave oven and frying. For the color of the kimbugak made with the microwave oven or frying, L values decreased as the level of sea tangle powder increased. Color a and b values were lowest in the control group. The color values(L, a, and b) of the kimbugak puffed by frying were higher than those made using the microwave oven. The hardness of the kimbugak samples puffed using the microwave oven were not significantly different according to levels of sea tangle powder, and in the kimbugak puffed by frying, the lowest hardness was in the sample with 6% sea tangle. In sensory evaluations, color and crispness were not significantly different among the samples. The flavor scores of the 4% and 6% samples puffed by frying were higher than those of the kimbugak samples puffed using the microwave oven. The overall acceptability of the kimbugak puffed by frying and containing 6% sea tangle powder was the highest. In conclusion, 4 and 6% sea tangle powder would be considered optimum amounts for kimbugak puffed by frying.

Evidence for the Association of Ce11u1ar Iron Loss in Nitric Oxide-induced Apoptosis of HL-60 Cells: Involvement of p38 Kinase, c-Jun N-terminal Kinase, Cytochrome C Release, and Caspases Pathways

Choi, Suck-Chei,Kim, Beom-Su,Yoon, Kwon-Ha,Song, Moon-Young,Oh, Hyun-Mee,Han, Weon-Cheol,Kim, Tae-Hyeon,Kim, Eun-Cheol,Jun, Chang Duk The Korean Society for Integrative Biology 2002 Korean journal of biological sciences Vol.6 No.2

Nitric oxide has high affinity for iron, and thus it can cause intracellular iron loss. We tested the idea that intracellular iron can be the primary target of NO toxicity by comparing the signaling mechanisms involved in cell death caused by iron depletion and that caused by NO. Treatment of HL-60 cells with a NO donor, S-nitroso-N-acetyl-DL-penicillamine (SNAP), decreased the intracellular iron level rapidly as that observed with the iron chelator deferoxamine (DFO). Iron chelators such as DFO and mimosine could induce death of human leukemic HL-60 cells by a mechanism requiring activation of p38 kinase, c-Jun N-terminal kinase, caspase-3 and caspase-8. DFO and SNAP also caused release of cytochrome c from mitochondria. Inhibition of p38 kinase by a selective inhibitor, SB203580, abolished the NO and DFO-induced cell death, release of cytochrome c, and activation of caspase-3 and caspase-8, thus indicating that p38 kinase lies upstream in the cell death processes. In a parallel situation, the cells that are sensitive to NO showed similar sensitivity to DFO. Moreover, simultaneous addition of ferric citrate, an iron-containing compound, inhibited the SNAP and DFO-induced activation of caspases and also blocked the NO-mediated cell cycle arrest at $G_1$ phase. Collectively, our data implicate that the NO-induced cell death of tumor cells including HL-60 cells is mediated by depletion of iron and further suggest that activation of p38 kinase lies upstream of cytochrome c release and caspase activation involved in this apoptotic process.

Prenatal diagnosis by direct DNA analysis in facioscapulohumeral muscular dystrophy (FSHD) families

Choi, Soo-Kyung,Lee, Je-Hyeon,Kim, Bong-Yoon,Kim, Hyung-Goo,Cho, Eun-Hee,Ryu, Hyun-Mee,Kim, Young-Joe Korean Society of Medical Genetics 1998 대한의학유전학회지 Vol.2 No.1

Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disorder which has been clinically shown to cause progressive weakness and result in atrophy of the facial muscles, shoulder girdle and upper arm muscles. The responsible gene for the FSHD has been located on chromosome 4q35-qter. The probes p13E-11 and pFR-1 detect DNA rearrangements associated with FSHD as under 28 kb DNA fragment in genomic southern analysis digested with EcoRI and the fragment contains 3.3 kb Kpn I tandem repeats. In this study, 4 fetuses with a family history of FSHD were analysed by genomic southern hybridization analysis with probes to determine whether they carried the deleted region. Of the 4 fetuses, three of them had mothers who were FSHD patients and the other one had a father affected with FSHD. After 10-11 weeks of gestation, we performed chorionic villi sampling and extracted DNA from uncultured and cultured tissue cells for the direct DNA analysis. The result of the southern analysis showed two fetuses having received about 15-18 kb of deleted genes from the father and the mother respectively, and found to be FSHD patients. The other two fetuses were shown to have two normal alleles from the parents and found to be normal. Two pregnancies which were determined to be normal were carried to term delivering two healthy babies.

Molocular Imaging and Nanomedicine(Biotechnology) : Liver-targeting property and siRNA delivery efficacy of recombinant human apolipoprotein A-I

( Hyeon Lee ),( Soo In Kim ),( Duck Hyang Shin ),( Tae Hyun Choi ),( Jong Chang Lee ),( Gi Jeong Cheon ),( Mee Hyein Kim ) 생화학분자생물학회 2008 생화학분자생물학회 춘계학술발표논문집 Vol.2008 No.-

광주·부산 일부 지역의 영·유아 부모의 영·유아 전용 화장품 사용 습관 연구

김현경 ( Hyeon-gyeong Kim ),최미옥 ( Mee-ok Choi ) 한국미용학회 2017 한국미용학회지 Vol.23 No.5

To prevent the corruption of cosmetics, personal-hygiene, awareness of cleanliness, and proper usage are important. Therefore, this study was conducted for infant’s parents living in Busan and Gwangju, for purpose of studying the usage habits about infant-cosmetics. Questionnaires conducted online, self-registering from March-15th to April-20th, 2017, and 459 copies used for final analysis. Survey items consisted of general characteristics, children-skin condition and infant-cosmetic’s usage habits. Results were as follows: First, in habit of washing hands before using cosmetics, related with age, child age, expert-counseling, parents answered significantly children-skin cleanliness affect their skin condition. Second, in clean habit of cleaning product containers, it was found over 50% parents clean and manage product containers, and if their children has atopic, sensitive-skin, or had expert consultation were answered significantly. Third, in habits about take some cosmetics out of containers using by tools, parents, office-workers, when child are girls, monthly income of less than 2million-won were related. Among factors affecting children's skin condition, some parents answered eating habits, nutritional status and skin cleanliness were influenced. Fourth, about closeness to using cosmetics after using, Busan and who earn over 2million-won in monthly were significantly showed. Therefore, it can be know importance of education through professional counseling, and it is expected many opportunities for infant parents should be given through various education on importance of using cosmetics correctly.

CSR 활동의 진정성이 기업태도에 미치는 영향에 관한 연구

이미영(Mee Young Lee),최현철(Hyeon Cheol Choi) 한국언론학회 2012 한국언론학보 Vol.56 No.1

Hot Water Extract of Leather Carp (Cyprinus carpio nudus) Improves Exercise Performance in Mice

Gong-Hyeon Lee,Dicky Harwanto,Sun-Mee Park,Jae-Suk Choi,Mi-Ryung Kim,Yong-Ki Hong 한국식품영양과학회 2015 Preventive Nutrition and Food Science Vol.20 No.4

The hot water extract of leather carp (Cyprinus carpio nudus) has been used as a nourishing tonic soup and as an aid for recovery from physical fatigue. In this study, we investigated the effect of leather carp extract on exercise performance in mice. Swimming endurance and forelimb grip strength were assessed following oral administration of the extract (once per day for 7 days) at a dose of 0.5 mg/10 L/g body weight. After 7 days, mice given the leather carp extract had significantly greater swimming endurance [105±18 s (P<0.05); 52% longer than day 0] and forelimb grip strength [1.18±0.05 Newton (P<0.01); 17% greater than day 0]. The extract increased muscle mass, but had little effect on body weight. Following the swimming exercise, blood glucose, glutathione peroxidase, and superoxide dismutase levels in extract-fed mice were significantly higher (145%, 131%, and 106%, respectively) than in the saline control group. Blood levels of high-density lipoprotein cholesterol were also significantly increased (128%) in mice given the extract compared to the controls. These results suggest that leather carp extract can improve physical exercise performance and prevent oxidative stress caused by exhaustive workouts.

영·유아 부모들의 자녀 화장품 구매태도 -광주·부산 지역을 중심으로-

김현경 ( Hyeon-gyeong Kim ),최미옥 ( Mee-ok Choi ) 한국미용학회 2018 한국미용학회지 Vol.24 No.2

With changes in social trends and increase in people’s investments in their child, infant & toddler cosmetics market has rapidly grown. For continuous development, it is important to set up differentiated marketing strategies. To examine infant & toddler parents’ cosmetics purchase attitude for their child, therefore, a survey was conducted against infant & toddler parents living in Busan and Gwangju. Online service using URL, a self-directed administered questionnaire survey was carried out from March 15 to April 20, 2017. A total of 459 copies were used for final analysis. Frequency analysis was performed to analyze general characteristics while chi-square analysis was conducted to examine infant & toddler cosmetics purchase attitude, using SPSS v. 21.0. The results follows: First, in terms of ‘purchase channel’, ‘Online’ was highest. Regarding ‘source’, ‘TV’ and ‘the Internet’ was highest. When asked how much money per month they usually spend for their child’s cosmetics, mostly answered ‘KRW 10,000-30,000.’ Second, regarding ‘the use of special offer period’ by general characteristics, the respondents mostly purchased cosmetics using the special offer. In terms of purchase age of cosmetics, 20- 30’s answered ‘3-6 months’ while 40’s answered ‘6 month and 12 months’ the best. Regarding ‘purchase preferences for high-price cosmetics for their child’, high-price products were preferred as the percentage of mother, vocation and average monthly income increased. Therefore, it is expected consumers will be more interested in purchasing if actively using marketing services such as Internet marketing and consumer discounting services. In addition to such, quality assurance measures should be prepared for those products that can not directly be confirmed online.

Comparison between leather carp extract and octacosanol on muscle and blood factors

Gong-Hyeon Lee,Dicky Harwanto,Sun-Mee Park,Jae-Suk Choi,Mi-Ryung Kim,Yong-Ki Hong 한국수산과학회 양식분과 2015 한국수산과학회 양식분과 학술대회 Vol.2015 No.10

놀이치료 과정에서 나타난 불안장애 아동의 놀이주제 및 치료진보 분석

최진현 ( Choi Jin-hyeon ),유미숙 ( Yoo Mee-sook ) 한국놀이치료학회 2018 한국놀이치료학회지(놀이치료연구) Vol.21 No.2

본 연구는 불안장애를 가진 만 7세 여아의 아동중심놀이치료 과정에서 나타난 놀이주제 특성과 치료진보에 대해 분석하는 데 목적이 있다. 놀이주제 분석 결과, 전체 회기에서 가장 두드러지게 표현된 놀이는 ‘관계’와 ‘불안/걱정’, ‘힘/통제’의 주제로 나타났다. 아동은 초기 단계에서 ‘관계’, ‘불안/걱정’, ‘슬픔/상실’, ‘의존’의 주제를 통해 라포 관계를 형성하였다. 중기 단계에서 아동은 ‘힘/통제’의 주제에서 ‘양육’과 ‘안전’, ‘보호’의 주제로 나아가며 점차 정서적 안정감과 안전기지를 형성하였다. 이후 놀이주제는 ‘혼돈/불안정’에서 ‘힘/통제’, ‘숙달’, ‘재생’의 주제로 변화되었다. 후기 단계에서는 ‘자기만족’과 ‘회복성’, ‘통합’의 주제가 주로 표현되었다. 다음으로 아동의 주증상의 변화를 검증하기 위해 치료진보 분석을 실시하였다. 가장 두드러진 치료 진보가 나타난 영역은 정서 영역의 ‘긍정적 감정’과 동기 영역의 ‘숙련놀이’, ‘좌절 견디기’, ‘놀이가 어려울 때도 계속 시도함’, 행동 영역의 ‘제한에 적절히 반응함’으로 나타났다. 본 연구는 불안장애 아동의 놀이 치료 과정을 다각적인 측면에서 분석하고 놀이주제의 특성을 밝혔다는 점에서 의의가 있다. 또한 아동의 성장과 치유가 어떤 역동적 과정을 거치며 나타나는지 진보 추이를 확인하고 치료성과를 검증하였다. The purpose of this study was to investigate play themes and the therapy progress of a 7-year-old girl with anxiety disorder in child-centered play therapy. Anxiety and Power/Control themes were observed intensively and repetitively. The themes in the initial phase comprised Relationships, Anxiety, Grief/Loss, and Dependency. The themes in the middle phase were changed gradually from Power/Control to Nurturing, Safety/Security and Protection. Self/sufficiency, Resiliency and Integration themes were mainly shown in the final phase. When the results of the progress of the play therapy was evaluated, there was significantly growth in the areas of Positive affect, Mastery play, Frustration tolerance, Keeps trying, and Responds to limits. The significances of this research lies in the fact that it can help to verify the characteristics of play themes and the dynamic therapy progress of anxiety disorder.