양수과다증 및 자궁내 태아사망과 동반된 Acardius Amorphous Monster의 1예

오창학(CH Oh),김근(K Kim),이순호(SH Lee),성기천(KC Sung),박영선(YS Park) 대한산부인과학회 1984 Obstetrics & Gynecology Science Vol.27 No.2

최근 본원에서 양수과다를 동반한 acardlius amorphous 1예를 경험하여 문헌고찰과 함께 보고 하는 바입니다. A case of a acardius amorphous monster associated with hydramnios &FDIU was terminated at full six months of gestation in 28 years old, para 1-0-2-1, women. We presen this case with brief review of literature.

Case Report : Co-development of autoimmune hepatitis and Sjogren`s syndrome triggered by the administration of herbal medicines

( Hyo Jeong Oh ),( Young Mi Mok ),( Moon Seong Ba다 ),( Bong Soo Seo ),( Tae Hyeon Kim ),( Keum Ha Choi ),( In Kyeom Hwang ),( Ji Eun Ra ),( Yong Reol Oh ),( Yong Sung Kim ),( Eun Young Cho ),( Haak Ch 대한간학회 2013 Clinical and Molecular Hepatology(대한간학회지) Vol.19 No.3

Autoimmune hepatitis (AIH) has been reported in association with Sjogren`s syndrome (55). Drug-induced AIH has been rarely reported. A rare case of the co-development of AIH and 55 in a 53-year-old woman after the consumption of herbal medicines is described. After admission, the patient complained of dryness in her mouth, and she was subsequently diagnosed with 55, which had not been detected previously. The patient`s bilirubin and aminotransferase levels initially decreased following conservative management; however, they later began to progressively increase. A diagnosis of AIH was made based on the scoring system proposed by the International Autoimmune Hepatitis Group. The patient was administered a combination of prednisolone and azathioprine, and the results of fOllow-up liver-function tests were found to be within the normal range. This is an unusual case of AIH and 55 triggered simultaneously by the administration of herbal medicines. ((Iin Mol HepatoI2013;19:30S-308)

The influence of Ne - Xe gas mixture ratio on vacuum Ultraviolet and infrared line in AC - PDP

Phil-Yong Oh,Il Ryong Cho,Yoon Jung,Ki Duck Park,Jun-Seok Oh,Chung-Gon Ryu,Guang-Sup Cho,Eun-Ha Ch 한국진공학회 2003 한국진공학회 학술발표회초록집 Vol.- No.-

비정질 CoFeSiB 세선 및 FeSiB 리본에서의 Matteucci 효과

오용주(Y.J.OH),김창진(CH.J.KIM),정인섭(I.S.JEONG),양충진(CH.J.YANG) 한국자기학회 1994 한국자기학회 학술연구발표회 논문개요집 Vol.4 No.1

벼 중생 고품질 내병·내풍성 신품종 ‘동보(東寶)’

Jeong-Il Kim,No-Bong Park,Ji-Yoon Lee,Oh-Deog Kwon,Dong-Soo Park,Jae-Ki Chang,Un-Sang Yeo,Byeong-Geun Oh,Jung-Hun Kang,Gihwan Yi,Jong-Hee Lee,Kuk-Hyun Jung,Seong-Hwan Oh,You-Cheon Song,Do-Yeon Kwak,Ch 한국육종학회 2012 한국육종학회지 Vol.44 No.2

‘동보’는 국립식량과학원 영덕출장소에서 1996년 하계에 밥맛이 뛰어나면서 재배 안정성이 높은 벼 품종을 육성할 목적으로 내풍성이면서 각종 병해에 강한 영덕19호를 모본으로 밥맛이 우수한 ‘고시히카리’를 부본으로 인공교배를 실시하고, 1996/1997 동계에 24개체의 F1 식물체를 양성하여 YR 18320의 교배번호를 부여하였다. 1997년 하계포장에 F2 집단 전개 후 선발하여 1998년 하계에 F3 세대 51계통을 육성하고, 이후 F4 ~ F8 세대를 계통육종법으로 전개하여 내도복성이면서 풍해에 강하고 병해에 안정적인 저항성을 나타내는 계통을 선발하여 2006년 생산력검정예비시험, 2007년 생산력 검정본시험을 실시한 후 완전미율이 높고 식미가 우수하면서 재배 안정성이 높은 YR18320-21-1-1-2-2-2을 선발하여 ‘영 덕49호’로 명명하였다. 2008년부터 2010년까지 3년간 지역 적응시험을 실시한 결과 중생종이면서 쌀 품위가 좋고 밥맛이 양호하며 내풍성과 내병성에 양호한 것으로 평가되어 2010년 12월 농작물 직무육성 신품종 선정위원회에서 국가 품종목록으로 등재 할 것을 결정하고 ‘동보’로 명명하여 적응 지역인 동남부해안지, 중부평야 및 남부중산간지에 보급하게 되었다. ‘동보’의 출수기는 보통기 재배에서 평균 8월 13일로 ‘화성벼’보다 1일 늦은 중생종 품종이다. 직립 초형이고 탈립 은 잘되지 않고 이삭추출은 양호 하고 까락이 거의 없다. 수 당립수는 ‘화성벼’보다 약간 많은 편이고 현미천립중은 23.6g으로 ‘화성벼’보다 더 무겁다. 도정특성과 완전미률은 ‘화성벼’보다 약간 좋은 편이고 외관특성이 맑고 투명하며 밥맛은 ‘화성벼’보다 우수하다. 불시출수는 안되는 편이나 수발아는 ‘화성벼’보다 더 잘되고, 위조현상에 강하고 성숙기 엽노화가 느린 편이며 내냉성은 ‘화성벼’와 같은 수준이다. 잎도열병 밭못자리 검정 결과 중도저항성을 보였고 줄무늬잎마름병과 흰잎마름병(K 1 , K 2 , K 3 )에는 강하나 오갈병 및 검은줄오갈병 에 약하고 벼멸구 등 충해에는 감수성이다. ‘동보’의 수량성 은 ’08 ~’10년 3개년간 실시한 지역적응시험 보통기 보비재배 4개소에서 5.71 MT/ha로 ‘화성벼’ 대비 3% 증수되었으며, 이모작재배에서는 4.79 MT/ha ‘남평벼’ 대비 4% 감수되었고, 만식재배에서는 4.75 MT/ha로 ‘남평벼’와 같았다. ‘동보’의 적응지역은 동해안냉조풍지, 중부평야지 및 남부중산간지이다. A new rice variety ‘Dongbo’ is a japonica rice (Oryza sativa L.) with good eating quality, lodging tolerance, and resistance to rice stripe virus (RSV) and blight bacterial disease (BB). It is developed by the rice breeding team of Yeongdeog Substation, National Institute Crop Science, RDA in 2010. This variety derived from a cross between ‘Yeongdeog19’ with good grain quality and wind tolerance and ‘Koshihikari’ with good eating quality conducted in 1996 summer. A promising line, YR18320-21-1-1-2-2-2, selected by pedigree breeding method was designated as the name of ‘Yeongdeog49’ in 2007. After the local adaptability test was carried out at nine locations from 2008 to 2010, ‘Yeongdeog49’ was released as the name of ‘Dongbo’ in 2010. ‘Dongbo’ is short culm length as 71cm and medium-growth duration. This variety is resistant to races, K 1 , K 2 , and K 3 of bacterial blight and stripe virus and moderately resistant to leaf blast disease with durable resistance, and also has tolerance to unfavorable environment such as cold and dried wind. ‘Dongbo’ has translucent and clear milled rice kernel without white core and belly rice, and good eating quality as a result of panel test. The yield potential of ‘Dongbo’ in milled rice is about 5.71 MT/ha at ordinary fertilizer level of local adaptability test. This cultivar would be adaptable to middle plain, mid-west costal area, and south mid-mountainous area.

얇은 자궁내막을 갖은 환자에 있어서 과배란 유도시 에스트라디올 추가요법의 효용성

오기석,조동제,김세광,권혁찬,양현원,장기홍,황경주,유정현,이치형 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.3

1994년 11월 1일부터 1997년 8월 31일까지 본원 불임크리닉에서 체외수정 및 배아이식술을 시술받은 491주기를 대상으로 hCG 투여시에 내막의 두께에 따라 체외수정 및 배아이식술의 결과를 분석하고 얇은 자궁내막을 가진 환자군에서 배아를 바로 이식하지 않고 동결 보존 후 해빙 배아이식술을 시행한 군과 과배란 유도 과정 중 에스트라디올 추가요법을 시행한 군에서 자궁내막의 반응과 그에 따른 임신율을 분석하여 다음과 같은 결론을 얻었다. 배란유도 중 hCG 투여시 자궁내막 두께가 7 mm 미만인 경우 배아를 동결시키고 이후 에스트로젠의 투여기간을 연장한 자궁내막에 이식을 하며 이전 주기 혹은 불임기초검사 중에 배란기 내막 상태가 7 mm 미만인 경우 GnRHa 장기투여법에 estradiol valerate를 추가하는 것이 효과적이라고 사료된다. It is known that adequate endometrial thickness is an important prognostic factor for implantation in natural cycles, in assisted conception cycles employing ovulation induction and ovum recipient cycles using hormone replacement therapy. Recently the thickness of the endometrium has been highly correlated with histological maturation, and in patients with thin endometrium increased dosage and duration of estradiol supplementation has led to increased endometrial maturation thus stressing the importance of endometrial thickness. In this study, the results of estradiol supplementation in patients with abnormally thin endometrium who are undergoing IVF-ET was observed and to evaluate the endometrial response and to compare the pregnancy outcome. From November 1st, 1994 to August 31st, 1997, 491 IVF-ET cycles were studied, which were divided into several groups. The first group was 451 cycles where the endometrial thickness was more than 7mm at the time of hCG injection, the second group was 15 cycles where the endometrial thickness was less than 7mm at the time of hCG injection, the third and fourth group was where the endometrial thickness was less than 7mm from the previous cycle to the time of hCG injection, in which the third group was 12 cycles where embryo transfer was not completed immediately but later after freezing, and in which the fourth group was 13 cycles which received estradiol supplementation during ovulation induction. The endometrial thickness averaged 10.0±0.1 mm in Group 1 and only 5.8±0.1mm in Group 2, but after estradiol supplementation which resulted in longer endometrial exposure to estrogen, 7.9±0.5 days in Group 2, 19.8±0.7 days in Group 3, 16.7±0.9 days in Group 4, showing significant increase[p<0.05]. In Group 3, 11 of 12 cases, and 10 of 13 cases in Group 4 the endometrial thickness improved to more than 7mm, along with the average thickness which increased to 7.1± 0.5 mm and 8.3±0.5 mm, respectively. There was no significant difference with regard to number of embryos transferred, cumulative embryo score, number of embryos of more than Grade II-1 between the groups. The clinical pregnancy rate and ongoing pregnancy 27.7% and 22.3% respectively, but in Group 2 the clinical pregnancy rate was only 6.6%. However, in Group 3 and Group 4 where estradiol supplementation was administered, the clinical pregnancy rates were 25.0% and 38.5% respectively, and the pregancy rates beyond 12 weeks of gestation reached 25.0% and 30.8% respectively. In conclusion, in cases where thin endometrium is observed at the time of hCG injection during IVF-ET it is recommended to freeze the embryo and then conduct the transfer after prolonging the length of estradiol administration, but in cases where the the endometrium is not adequate in the previous cycle or during basic infertility work-up, it is suggested that estradiol supplementation to long protocol GnRHa is effective.

자궁부속기 질환의 치료에 있어서 골반경 수술과 개복수술의 비교연구

오병찬,김종덕,류철희,김관식 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.4

목적: 양성종양의 불필요한 개복수술과 악성종양의 부적절한 골반경수술을 피하고 자궁부속기종양 골반경수술의 비율을 높이기 위함 연구방법: 정해진 개복수술의 지침에 따라 자궁부속기 종괴의 개복 또는 골반경수술을 시행하고 수술방법, 수술시간, 재원기간, 합병증, 개복수술 요인과 개복수술의 적합성 여부에 대한 수술자 의견 등이 분석됨. 결과: 18개월간 자궁부속기 종괴로 개복수술[159명]과 골반경수술[129명]이 시행됨. 개복수술/골반경수술 비율은 전체적으로 55.2%/44.8%, 비종양성 종괴는 44.5%/55.5%, 양성종양은 58.1%/41.9%, 경계성종양 100.0%/0.0%, 악성종양 91.7%/8.3%임. 주요 개복이유로 비종양성 자궁부속기 종괴는 복막염 또는 혈복강을 의심하는 증상 징후와 함게 불안정한 생체활력징후[32.1%]와 중증 골반강내 유착의 강력한 의심이나 확인[24.5%], 양성종양은 세밀한 낭종박피술이 필요한 직경 6cm 이상의 종괴[26.7%]와 중증 골반강내 유착의 강력한 의심이나 확인 [18.6%]임. 난소암 골반경수술은 1례[0.78%]임. 수술자는 개복수술의 28.9%가 골반경수술에 적합했을 것으로 판단함. 결론: 자궁부속기 종양에 있어 골반경수술이 개복수술보다 더 나은 방법이며 유착을 의심하는 환자나 의심스런 종괴에 대해서도 신중한 골반경수술의 재고가 필요하리라 사료됨. 또 한편 골반경수술 적용을 위해 더 주의깊은 수술 전, 수술 중 검사가 이뤄져야 할 것임. Objective: To increase proportion of pelviscopic surgery, and besides, avoid unnecessary laparotomy for benignity and pelviscopic surgery of malignancy in adnexal masses. Methods: Adnexal masses were managed by laparotomy or laparoscopy under the stated guideline. We analyzed data of the surgical procedure, operative time, hospital stay, and complication, guideline applied and the operator`s opinion on the adequacy of each laparotomy. Results: Over an 18-month period, laparotomy [n=159] or pelviscopy [n=129] were performed. Mean operative time and hospital stay in the pelviscopy group were shorter than those in the laparotomy group. The proportion of laparotomy/pelviscopy were 55.2%/44.8% in overall, 44.5%/55.5% in non-neoplastic tumors, 58.1%/41.9% in benign neoplasm, 100.0%/0.0% in borderline tumor and 91.7%/8.3% in malignancy. The main reasons of laparotomies were unstable vital sign with some symptoms and signs of generalized peritonitis or hemoperitoneum[32.1%] and suspected severe pelvic or abdominal adhesion [24.5%] in non-neoplastic tumor. The patients of benign neoplasms had laparotomies chiefly due to elaborate enucleation in the cyst of diameter 6cm for fertility[26.7%] and suspected severe pelvic or abdominal adhesion [18.6%]. Pelviscopic surgery of ovarian cancer was 1 case [0.78%]. Operator was of opinion that the rate of inadequacy in laparotomies was 28.9% in overall. Conclusion: Pelviscopic surgery is superior to laparotomy in the management of adnexal masses and may be considered prudently in patients of pelvic adhesion suspected and in adnexal tumors those can`t confirm as benignancy. In addition to preoperative evaluations, operative findigs and frozen biopsy should be obtained more carefully for pelviscopy of adnexal tumors.

The Attitudes of Nursing Students towards Anatomy Learning in the Dissecting Room

OH Chai,RA Ko,YK Kim,HL Zhao,HT Kim,CH Song,EH Han 대한체질인류학회 2011 대한체질인류학회 학술대회 연제 초록 Vol.54 No.-

고도 정제된 인간의 FSH[highly purified FSH , FSH-HP]를 사용한 단순화된 체외수정 및 배아이식술의 효용성

오기석,권혁찬,장기홍,황경주,김지영,유정현,이치형 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.5

1994년 12월 1일부터 1997년 8월 31일까지 본원 불임크리닉에서 체외수정 및 배아이식을 받은 504주기의 환자를 대상으로 FSH-HP를 사용한 단순화된 과배란유도법과 다른 약제를 사용한 단순화된 과배란유도법 사이의 과배란 유도의 특성, 난자 및 배아의 발달 및 임신 결과를 비교하고자 본 연구를 수행하였다. FSH-HMG 투여법[84 주기], GnRH agonist 단기 투여법[142 주기] 및 장기 투여법[175 주기]과 FSH-HP 투여법[103 주기]을 사용한 단순화된 체외수정 및 과배란유도법을 시행한 결과 FSH-HP를 사용한 과배란유도 방법은 GnRH agonist 장기투여법에 비하여 과배란유도기간[7.6±0.2일 vs 9.0±0.1일] 및 과배란유도제제 투여 총량[26.4±1.1개 vs 34.8±1.2개]은 유의하게 적으면서 조기황체화, 취소율 및 난소 과자극증후군의 발병 빈도는 그다지 높지 않 았다. 자궁내막의 반응 또한 좋았으며 혈중 에스트라디올 농도가 GnRH agonist 장, 단기투여법에 비하여 유의하게 낮았으나[p$lt;0.05] 난자 및 배아의 발달은 정상적으로 이루워졌으며, 통계학적 유의성은 없었으나 오히려 다소 높은 착상율과 낮은 유산율로 높은 지속 임신율을 유지할 수 있었다. 또한 환자 스스로 피하주사 할 수 있어 체외수정 및 배아이식술의 전과정을 최대한 단순화시켜 의료진과 환자 모두에게 효율적이며 편리하게 할 수 있었다. 따라서 FSH-HP를 이용한 단순화된 체외수정 및 과배란 유도 방법은 기존의 과배란 유도법을 대체할 수 있는 좋은 방법으로 사료된다. Objectives : To compare simplified ovulation induction employing FSH-HP with that of simplified ovulation induction employing other pharmacologic agents with regard to ovulation induction characteristics, oocyte and embryo development, and pregnancy outcome. Methods : From December 1, 1994 to August 31, 1997, those cycles who underwent in vitro fertilization and embryo transfer with FSH-HMG [84 cycles], GnRH agonist short protocol [142 cyclse] and long protocol [175 cycles] and FSH-HP [103 cycles], totalling 504 cycles. Results : The duration of ovulation induction with FSH-HP was 7.6±0.2 days, which was significantly shorter than the 9.0±0.1 days when GnRH agonist was used, and the total dose of agents were also significantly less [26.4±1.1 ampules vs 34.8±1.2 ampules]. The incidence of premature luteinization, cycle cancellation rate, and OHSS development was similar between the two groups. In the FSH-HP group good endometrial response was observed. The serum estradiol concentrations were significantly lower than the GnRH agonist short and long protocols [p$lt;0.05], but there was normal oocyte and embryo development. Rather, although there was no statistical significanse, the implantation rate was relatively higher whereas the abortion rate was relatively lower, leading to higher ongoing pregnancy rate overall. Conclusion : Ovulation induction with FSH-HP enables subcutaneous drug administration by the patient herself, therefore simplifying as much as possible the in vitro fertilization and embryo transfer process and affording conveniency for both the patient and the hospital. It is therefore suggested that simplified protocols in IVF-ET with highly purified FSH [FSH-HP] for ovulation induction is an efficient alternative to current standard protocols.

46, X del(X)(p11.2) 1예

오보훈,김창훈 대한산부인과학회 1993 Obstetrics & Gynecology Science Vol.36 No.7

저자들은 최근 경희의료원에서 성적소아증, 원발성 무월경, 성장지연을 동반한 19세 여아에서 46,Xdel(p11.2) Turner 씨증후군 1례를 경험하였기에 간단한 문헌적 고찰과 함께 보고하는 바이다. The term Turner`s syndrome refers to those instances of gonadal dysgenesis associated with somatic anomalies such as sexual infantilism,webbing of the neck, cubitus valgus and others. The anomalies of X chromosome structure include the deletion in the long arm or the short arm of chromosome, ring chromosome and isochromosome. Lack of Xp, and especialluY Xcen-Xp11, may cause full-blown Turner syndrome. How-ever, individual Turner symptoms including gonadal dysgenesis seem to be randomly distri-buted with respect to the dirrerent Xp and Xq deletion, although breakpoints distal to Xq25 do not give rise to any phenotypic anomalies except in a f ew cases of secondary amenorrhea or premature menopasue. One of the main symptoms in the Turner syndrome is ovarian dystenesis, which express itself as primary or secondary amenorrhea. Of the carriers of an Xp- or Xq-chromosome,65% and 93%, respectively, suffer from ovarian dysgenesis, whereas all idic(Xp-)and idic(X-q-) chromosomes cause primary or secondary amenorrhea. All XO women and 88% of the carriers of a terminally deleted Xp are short. However,43% of the Xq- carriers also show short stature. The chief cause of shortness is apparently the lack of the very tip of Xp. The authors hae seen a patient with gonadal dysgenesis and short stature. The patient revealed sexual infantilism, no pubic hairs also, but somatic anomalies such as webbing of the neck and cubitus valgus could not be seen. Cytogenic analysis the 46,X del(X)([p11.2) complement.