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가족적으로 발생한 쿠싱증후군 : 색소침착성 다결절성 부신피질 이형성증 3 예
정성광,김신우,서인수,장세국,박윤규,김법완,손윤경,김보완,서예경,김정국,하승우,곽정식 대한내과학회 1995 대한내과학회지 Vol.49 No.2
Pigmented multinodular adrenocortical dysplasia is a rare cause of Cushing's syndrome in infants, children and young adults. The disease is characterized by an ACTH independent adrenocortical hyperfunction without autonomously functioning adrenocortical neoplasm. Clinical symptoms are features of Cushing's syndrome and spotty facial pigmentation (lentigines and blue nevi). The biochemical findings include: 1) no suppression of urinary corticosteroid excretion after administration of dexamethasone. 2) no response to metyrapone or ACTH administraion; and 3) undetectable, low, or normal plasma levels of ACTH. Adrenal glands are normal or slightly enlarged and may or may not have discernible nodules on computed tomography scans. Bilateral total adrenalectomy cures the Cushing's syndrome. The familial occurrence, especially when to be found in combination with extra adrenal disorders, was considered indicative of 'Carney's complex'. Recently we experienced 3 cases of Cushing's syndrome due to pigmented multinodular adrenocortical dysplasia in one family, so we report the cases with a review of literatures.
Kim, Min Kyu,Kim, A-Young,Woo, Jae Young,Lim, Jong Choo,Jeon, Bup Ju,Lee, Joong Kee Elsevier 2016 JOURNAL OF ALLOYS AND COMPOUNDS Vol.680 No.-
<P><B>Abstract</B></P> <P>Surface modification of SnO<SUB>2</SUB>:F particles which obtained from a large-scale electron cyclotron resonance-metal organic chemical vapor deposition system was carried out by two consecutive processes: electroless plating processing and annealing. First, Ni film on the SnO<SUB>2</SUB>:F and Ni nanoclusters were observed after Ni electroless plating; the film on the SnO<SUB>2</SUB>:F was then converted to Ni<SUB>3</SUB>Sn<SUB>2</SUB> after annealing at 800 °C under an argon atmosphere. A Ni<SUB>3</SUB>Sn<SUB>2</SUB> bimetallic structure formed instead of NiO during the annealing process because of the presence of carbon impurities in SnO<SUB>2</SUB>:F. The surface-modified Ni<SUB>3</SUB>Sn<SUB>2</SUB>-covered SnO<SUB>2</SUB>:F with Ni nanoclusters (SnO<SUB>2</SUB>:F@Ni<SUB>3</SUB>Sn<SUB>2</SUB>/Ni-nc) was employed as an anode material for lithium-ion batteries. The inactive Ni in Ni<SUB>3</SUB>Sn<SUB>2</SUB> acts as a buffer matrix against the Sn active material during the charge-discharge reactions, enhancing the electrochemical performance. The Ni nanoclusters in SnO<SUB>2</SUB>:F@Ni<SUB>3</SUB>Sn<SUB>2</SUB>/Ni-nc perform dual functions: they not only improve the conductivity as the contacting media, but also increase the initial columbic efficiency by the decomposition of Li<SUB>2</SUB>O—an electrochemically irreversible material. An outstanding reversible capacity of 600.69 mA h g<SUP>−1</SUP> and a coulombic efficiency of 99.23% for SnO<SUB>2</SUB>:F@Ni<SUB>3</SUB>Sn<SUB>2</SUB>/Ni-nc were observed at the 350<SUP>th</SUP> cycle under 200 mA g<SUP>−1</SUP> in the our experimental range.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Employment of SnO<SUB>2</SUB>:F/Ni<SUB>3</SUB>Sn<SUB>2</SUB>/Ni nanoclusters composite as anode material for LIBs. </LI> <LI> Electroless plating and annealing were used for preparation of SnO<SUB>2</SUB>:F/Ni<SUB>3</SUB>Sn<SUB>2</SUB>/Ni-nc. </LI> <LI> Electrochemical stability was attributed to the Ni<SUB>3</SUB>Sn<SUB>2</SUB> intermetallic structure. </LI> <LI> Ni nanoclusters enhance coulombic efficiency and improve conductivity as well. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>The Ni<SUB>3</SUB>Sn<SUB>2</SUB> coated SnO<SUB>2</SUB>:F with Ni nanoclusters (SnO<SUB>2</SUB>:F@Ni<SUB>3</SUB>Sn<SUB>2</SUB>/Ni-nc) was successfully prepared by sequence process, such as simple electroless plating and annealing. The novel SnO<SUB>2</SUB>:F@Ni<SUB>3</SUB>Sn<SUB>2</SUB>/Ni-nc exhibited more excellent electrochemical performances. The excellent electrochemical performance of SnO<SUB>2</SUB>:F@Ni<SUB>3</SUB>Sn<SUB>2</SUB>/Ni-nc can be attributed to a synergy effect of stability of Ni-Sn intermetallic structure and the presence of Ni nanoclusters.</P> <P>[DISPLAY OMISSION]</P>
Inverse Estimation of Surface Temperature in Nanoscale Using the Artificial Neural Network
Bup Sung Jung(정법성),Sun Kyung Kim(김선경),Woo Il Lee(이우일) 대한기계학회 2005 대한기계학회 춘추학술대회 Vol.2005 No.5
The inverse heat conduction problem (IHCP) is a problem of estimating boundary condition from temperature measurement at one or more interior points. In this work, an inverse heat conduction problem for nanoscale structure is studied. The conduction phenomenon is modeled using the Boltzmann transport equation. Phonon-mediated heat conduction in one-dimension is considered. One boundary is exposed to an unknown temperature and the other boundary, where temperature observation takes place, is subject to a known boundary condition. The artificial neural network with back-propagation algorithm is applied to inverse estimation of the unknown temperature. Sample results are presented and discuss.
김성아,이종우,김법완,신용철 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.2
This is the first report on an occupational bladder cancer in Korea. The case is 41 years old man who worked as a dyer for 17 years at two dyeing factories, which handled nylon and polyester fabrics in Taegu. He was exposed to many kinds of dyes during weighing, mixing, dissolving and dyeing processes. Among many kinds of acid, disperse and direct dyes that he has been exposed to, several dyes have confirmed to contain benzidine-based dyes, one was o-tolidine-based dye, and one was o-dianisidine-based dye. He visited a hospital due to the gross hematuria and urinary frequency in June, 1998, and he had radical cystectomy with ileal conduit diversion. He had smoked a half-pack of cigarette for 20 years. The main risk factor of bladder cancer is smoking, however, he was relatively a light smoker than usual Korean men. He was exposed to the definite occupational carcinogen even though the level was relatively lower than that of dye manufacturers. His age was younger than the prevalence age of bladder cancer caused by smoking. These evidences support that the dyer's bladder cancer could be related to the occupational exposure to benzidine-based dyes.