원문 : 좌업 시간과 알코올 섭취가 30대 남자 사무직 근로자의 혈압과 혈관탄성에 미치는 영향

조봉오 ( Bong Oh Cho ),이인녕 ( In Yeong Lee ),정균근 ( Gyun Geun Jeong ),장창현 ( Chang Hyun Jang ) 한국운동생리학회(구 한국운동과학회) 2014 운동과학 Vol.23 No.3

조봉오, 이인녕, 정균근, 장창현. 좌업 시간과 알코올 섭취가 30대 남자 사무직 근로자의 혈압과 혈관탄성에 미치는 영향. 운동과학, 제23권 3호, 241-248, 2014. 본 연구의 목적은 일과 중 대부분을 좌업근무 형태로 업무를 수행하고, 스트레스로 인해 음주가 잦고, 운동이 부족한 30대 남자 사무직 음주자 15명을 대상으로 좌업 시간과 알코올 섭취가 혈압과 혈관탄성에 미치는 영향을 분석하여 사무직 근로자에게 건강관리에 필요한 정보를 제공하는데 있다. S대학 운동 생리학 실험실에서 사전 인적 사항과 설문을 작성하고, 신장, 체중, 채혈, 혈압, 혈관탄성, BMI를 측정하였다. 알코올 섭취 횟수, 섭취량, 좌업 시간, 그리고 음주 섭취 전과 후 및 시간대별 (10분, 40분, 60분) 혈압과 혈관탄성의 변화를 측정 분석한 결과를 요약하면 다음과 같다. 1) 평균 좌업시간이 9.87시간, 음주횟수 및 음주량은 월 평균 9.13회와 12.47잔 이였다. 2) 알코올 섭취횟수 및 섭취량에 따른 BMI, TC, LDL-C, HDL-C, 혈압과 혈관탄성 비교에서 알코올 섭취횟수에서 좌상지 혈관탄성은 통계적으로 유의한 차이를 나타냈다(p<.05). 3) 알코올 섭취 전, 후 비교 분석 결과 우상지와 좌상지의 혈관탄성에서 통계적으로 유의한 차이가 나타났다(p<.05). 4) 알코올 섭취 후 시간대별 우상지 혈관탄성은 통계적으로 유의한 차이를 나타냈다(p<.05). 이상의 결과를 종합해 볼 때, 좌업 시간이 혈압과 혈관탄성에 미치는 영향은 통계적으로 유의하게 나타나지 않았고, 알코올 섭취는 혈관탄성에 통계적으로 유의한 차이를 나타냄을 알 수 있었다. 따라서 이는 직장생활의 스트레스를 음주로 해소하는 경향이 있음을 보여주며 건강에 부정적인 영향을 주고 있음을 알 수 있었다. 또한, 신체가 음주에 적응되어 실험 시 섭취한 적은 양(1/2병)은 1회 12.47잔에 비해 혈압과 혈관탄성에 큰 영향을 미치지 못한 것으로 사료된다. Cho, Bong-Oh, Lee, In-Yeong, Jeong, Gyun-Geun, Jang, Chang-Hyun. Effects of Sedentary Occupation Time and Alcohol Intake on Blood Pressure and Vascular Compliance in 30s Male White-Collar Workers. Exercise Science, 23(3): 241-248. 2014. The purpose of this study was to examine effects of duration of sedentary office work and alcohol intake on blood pressure and vascular compliance in male subjects who were office workers aged between 30 to 39 and frequently drink alcoholic beverages to cope with their stress without exercising for health. The study was to provide health-related information necessary for white-collar workers. We collected data of demographic information, height, weight, blood sample, blood pressure, vascular compliance, and BMI from 15 subjects in S University`s Exercise Physiology Laboratory, and analyzed the frequency and amount of alcohol intake, duration of sedentary work, and changes in blood pressure and vascular compliance at diffident time points (10, 40, and 60 minutes post drinking) from baseline. I t was found that the average time of sedentary work was 9.87 hours, drinking 9.13 times a month on average, 12.47 glasses of alcohol beverages per drink. In comparison of BMI, TC, LDL-C, HDL-C, blood pressure and vascular compliance upon the frequency and amount of alcohol intake, the upper left limb`s vascular compliance had a statistically significant difference (p<.05). In the result of the comparative analysis of pre-and post-drinking, vascular compliance was significantly different in the upper right and left limbs (p<.05). Vascular compliance in the upper right limb after drinking significantly changed (p<.05). As a result, the duration of sedentary work had no statistically significant difference in blood pressure and vascular compliance. T he vascular compliance after drinking h ad a statistically significant difference. This suggested that the result was an index that shows the trend of the office workers releasing their work stress by drinking alcoholic beverages, and that drinking had negative impacts on them. In addition, a small amount of intake (a half bottle) at the test time, after the body was adjusted to drinking, compared with 12.47 glasses per intake, had no great impacts on blood pressure and vascular compliance.

육상 멀리뛰기경기 결승진출 선수들의 기록 분석

오봉석,윤신중 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

The present study was carried out to find the attempt that exhibits the Lest record during long jump competition. The subjects of this study were 72(male=40, female=32.) long jump athletes who passed elimination in national track and field events, These subjects practiced six long jump during their competition Therefore, total trials of long jump were 432. Arid these records were recognized as official records by Korea Amateur Athletic Federation. The results were as follows; First, total Repeated ANOVAs revealed that there was no significant trial difference, but separate Repeated ANOVAs revealed that there was significant trial difference in gender records. Second, there was significant trial difference in male records, and post-hoc revealed that the record of 5 trial was the highest. Third, there was no significant trial difference in female records. From these results, I suggest that it is important for long jump athletes and their coaches involved in competition to be familiar with the variety of mechanism which can be leaded fatigue, and that it is desirable to exhibit the Lest competition record during elimination period.

回轉굽힘을 받는 複合組織網의 疲勞强度와 破壞擧動에 관한 硏究

吳世旭,金奉均 東亞大學校 1982 東亞論叢 Vol.19 No.1

The quality and reliability of various steel materials used in industrial machinery have become a great importance as industry developes. For this reason a study on dual phase steel have been performed by the reporter with great interest. The annealed steel and MEF steel. FEM steel of dual phase specimens were prepared on hollowed specimen. A rotated bending fatigue test was performed on these specimens. The relationship between fatigue crack propagation status, velocity and stress intensity factor was investigated during the test. The results of the test are as follows. 1. The fatigue limits of MEF and FEM showed 34% and 26% increases respectively compared to the annealed specimen. 2. The fatigue-life of MEF and FEM showed 15.6 and 10.5 times increase respectively over the annealed specimen. For initial crack occurance, MEF and FEM showed 40 and 15 times, increase over the annealed specimen. 3. The relationship between propagative speed of fatigue-crack and stress intensity factor is formulated as shown below : Annealed : ?? FEM : ?? MEF : ?? 4. The crack occurance in a ferrite particle of dual phase steel propagated thru the thinnist border of the martensite second phase for MEF specimen, and propagated alongside the border of the martensite second phase for FEM.

群産灣의 海洋基礎 調査

吳錫欣,吉奉燮 圓光大學校 1984 論文集 Vol.18 No.2

To investigate the oceanographic condition, samples were taken from five stations(St. 1-St, 5. in Gun San bay on alternate month from June, 1983 to April, 1984. Four items for physico-chemical analysis and four items for biological analysis were carried out. 1. Water temperature : Annual average variation of temperature at all sampling sites ranged from 2 ℃ to 29℃. The highest average value of temperature was 16.7℃ at the high water of station 5 and the lowest average value was 15.3℃ at the high water of station 3. 2. pH : The variation of pH value at the station 4 and the station 5 were relatively higher than those in the station 1-3. the highest value on high water pH 8.33 on October, 1983 and the lowest value was pH 7.35 at low water on February, 1984. 3. Dissolved oxygens : The dissolved oxygen content of the high water and the low water were relatively low at all stations during the entire period of investigation. The average values of dissolved oxygen at the high water varied between 4.71mg/ℓ and 7.88mg/ℓ. The lowest dissolved oxygen content with 4.71mg/ℓ was form at the high water on February, 1984 and the highest dissolved oxygen content with 8.41 mg/ℓ was formed at the low water on February, 1984. 4. Biological oxygen demand : The maximum concentration of biological oxygen demand(BDD) was 12.5 mg/ℓ at high water in July, 1983 and the minimum was 0mg/ℓ at the high water in February, 1984. 5. Phytoplankton : The species of phytoplankton which was appeared in all sampling stations were 36 genera, 78 species including 3 variaties. 6. General bacteria : The population densities of total general bacteria were very highly value from 2.12×10³ cells/㎖ to ?? cells/㎖. 7. Coliform group : The monthly population densities by coliform on the 5 stations were most hihghly value from 1.47×10⁴ cells/㎖(high water) to 2.95×10⁴ cells/㎖(low water) at August, 1983.

당뇨병 Goto-Kakizaki 랫트에서 호모시스테인의 대사조절

오정민,여수정,김봉희,김상겸 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

Elevation of homocysteine levels is a risk factor for cardiovascular diseases and liver diseases. It has been reported that both streptozotocin-induced type I diabetic rats and obese type II diabetic rats have plasma total homocysteine lower than each control rats. We determined the effects of lean type II diabetes on homocysteine levels using type 2 diabetic Goto-Kakizaki rats. The concentrations of serum glucose were increased to ∼two-fold of control levels and the total cholesterol levels were also increased in GK rats. Hepatic aspartate, histidine, threonine, alanine and methionine levels were significantly increased in GK rats. Plasma aspartate and glutamate levels were elevated, but threonine and arginine levels were decreased in GK rats. Plasma total homocysteine levels were not changed in GK rats, but hepatic total homocysteine levels were increased to ∼-three-fold of control levels. These results suggest that hepatic metabolism of sulfur-amino acid may be altered in diabetic condition.

농촌지역 초등학교 유휴시설의 활용방안에 관한 연구 : 해남군 초등학교를 중심으로 Focused on the Elementary School in Hae-Nam

오재섭,이봉수,박향용,유창균,조용준 朝鮮大學校 建設技術硏究所 1998 建設技術硏究 Vol.18 No.2

Recently, number of elementary school students in the rural area have decreased due to move of population to the diminishment of birth population, the generation of idle facilities and even the trend of abolition of school presented problems. This paper was a study of the use plans and generation pattern of idle facilities in present school. And the targeted schools of this study were elementary schools located at Hae-Nam Province in Chun-Nam. The results are as follows : 1) While the number of the elementary school is continuosuly decreased up to now since 1980, the number of branch schools and closed schools is increasing and while general class is decreased continuously, multiple classes are increasing and so the utilization of idle facilities will be continued. 2) The utilization of idle facilities is most frequent in the use of school curriculm(67%), followed by the use of club activities and welfare facilities, but the use by residents is minimum. In the problems in using idle facilities, the lack of finance is most(68%), followed by the lack of illustrative data and technical problems and in the effects of using idle facilities, extra curriculum activities are best and followed by the use of local community and school curriculum. 3) In the most required facilities in using idle facilities, gymnasium and service area are highest and followed by laboratory, learning data room and library and in the common facilities with local residents, swimming pool is most frequent and followed by library.

장거리달리기 생활체육 동호인의 10㎞ 달리기 구간기록과 체중의 관계에 대한 사례연구

오봉석,조영제 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.6

This case study was carried out to elucidate whether body weight was affected by long distance run and to explore the relation body weight with the 10㎞ section records and to provide the prevention method of overweight and obesity and the elevation method of 10㎞ record to a lot of people interested in long distance run. The subject was thirty-nine years old male who has been taking part in 10㎞ run (1time/week) regularly for 6 months. And the section records of 10㎞ run were measured on 4㎞, 7㎞, 10㎞. The results were as followed: First, the body weight was significantly decreased after 10㎞ run, and the mean reduction extent was 1.02㎏. After six-month 10㎞ run(1time/week) the body weight was decreased about 3.39㎏(p<.001). Second, the relation of body weight with 10㎞ section records was significant(p<.01). Third, after six-month 10㎞ run(1time/week) the section records of 10㎞ were significantly shortened 1 minute 40 seconds in 4km, 2 minutes 10 seconds in 7㎞, 4 minutes 20 seconds in 10㎞(p<.001). Fourth, after 3 months of 10㎞ run(1time/week) the section record change modes of 10㎞ were continual. In summery, body weight was significantly reduced by 10㎞ run and has significant effect on the section records of 10㎞ run. And the accommodation period to 10㎞ run was about 3 months, so a person who interested in long distance run should put the first 3 months of long distance run to practical usage as an accommodation period and during this period he must more concentrate on running long distance than on shortening record.

마우스에서 회양목 추출물의 단회투여독성시험

오정민,조재훈,김봉희,김상겸 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

The single dose toxicity of Buxus microphylla var. koreana Nakai was evaluated in ICR mice. Twenty five mice of each sex were randomly assigned to five groups of 5 mice each and were administered singly by gavage at dose of 0, 222, 667, 2,000 and 5,000 mg/kg body weight. After single administration, signs of toxicity were observed every hour for the first 6 hours and every day for 14 days. At the end of 14-day observation period, all animals were sacrificed for gross postmortem examinations. Neither significant toxic signs nor death was observed during the observation period. In addition, no pathological changes were noticed in macroscopic examination at necropsy. These results indicate that the single oral administration of Buxus microphylla var. koreana Nakai did not cause any toxic effect at the dose of 5,000 mg/kg body weight for both sexes and LD_(50) of Buxus microphylla var. koreana Nakai is greater than 5,000 mg/kg body weight.

Protein kinase A 억제제인 KT5720이 글루카곤 매개성 항산화 효소의 발현감소에 미치는 영향

오수진,조재훈,박창식,김상겸,김봉희 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

We reported previously that glucagon decreased alpha- and pi-class glutathione S-transferases (GSTs) and microsomal epoxide hydrolase (mEH) protein levels in primary cultured rat hepatocytes. The present study examines the effects of protein kinase A (PKA) inhibitor, KT5720, on the glucagon-mediated decrease in expression of GSTs and mEH. To assess cell viability, lactate dehydrogenase release and MTT activity were examined in hepatocytes treated KT5720. Cell viability was significantly decreased in a concentration-dependent manner after incubation with KT5720 at the concentrations of I μM or above for 24 h, which was inhibited by the cytochrome P450 inhibitor SKF-525A. In contrast, another PKA inhibitor H89 (up to 25μM) was not toxic to hepatocytes. The glucagon-mediated decrease in expression of alpha- and pi-class GSTs and mEH was completely inhibited by 25μM H89 and attenuated by O.1μM KT5720. This study demonstrates that KT5720 may cause cytotoxicity in rat hepatocytes through cytochrome P450-dependent bioactivation. The present study implicates PKA in mediating the inhibitory effect of glucagon on expression of alpha- and piclass GSTs and mEH.

Cu^2+-quinolone 복합체 존재하 DNA의 DNase Ⅰ에 대한 가수분해 반응성 증가

吳鳳京,徐正仁,柳聲元,高東成 충남대학교부설 생명공학연구소 1991 생물공학연구지 Vol.1 No.-

특히, 그람음성 세균에 대한 활성을 가지며 Escherichia coli, Proteus 및 Klebsiella류의 감염에 의한 요도염(urinary tract infections)의 임상학적 치료에 유효함이 증명된1-5 합성 항균제인 nalidixic acid(lethy1-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid)를 비롯한 quinolones 항균제의 개발연구가6 국내외 공히 활발하게 진해되고 있음에도 불구하고 그 작용 메커니즘이 제대로 밝혀지지 못하고있는 실정이다. 이들은 DNA합성을 방해 하므로써 향균 기능을 갖는다고 알려져 있으나 그 표적물(target)이 무엇인가에 대하여는 불분명하다. 이들 quinolones는 생리적 pH에서 음이온으로 존재하므로 정전기적 반발로 인하여 다음이온성(polyanionic)인 DNA와의 직접적 상호작용 가능성이 배제되어 왔으며 일반적인 견해는 DNA gyrase subunit A가 nalidixic acid의 특이한 target인 것으로 알려져 있다.