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2P-213 전기방사법을 이용한 코어쉘 구조(PCL@Chitosan/Gelatin) 나노섬유 제조 및 특성 평가
한상영,홍상은,윤국로 한국공업화학회 2017 한국공업화학회 연구논문 초록집 Vol.2017 No.1
세포 성장의 지지체 역할을 하는 스케폴드(Scaffold)는 생체의 세포외기질(Extracellular matrix)과 유사하고, 세포친화력이 우수해야 한다. 본 연구에서는 전기방사법을 이용하여 세포외기질과 유사한 구조를 가지는 코어쉘 구조 나노섬유 시트를 제작하였다. 코어는 생분해성이며, 기계적 강도를 증가시키는 PCL(Polycaprolactone)을 사용하였다. 쉘은 생체적합성 및 세포친화력을 높이고자 키토산과 젤라틴을 혼합하여 사용하였다. 나노섬유의 코어쉘 구조는 광학현미경(Optical Microscope), 주사전자현미경(Scanning Electron Microscope), 투과전자현미경(Transmission Electron Microscope)을 통해 확인하였고, 물리·화학적 특성은 적외선분광기(Fourier Transform Infrared Spectroscopy), 인장력(Tensile Strength), 접촉각(Contact Angle), 열 중량 분석(Thermogravimetric analysis)으로 평가하였다. 제작한 코어쉘 구조(PCL@Chitosan/Gelatin) 나노섬유의 생체적합성, 기계·구조적 특성은 조직공학용 스케폴드에 응용할 수 있을 것으로 기대된다.
Effects of Implementation and Application of Realistic Digital Contents
한상영 한국인터넷방송통신학회 2019 Journal of Advanced Smart Convergence Vol.8 No.1
This study aims to explore the understanding of and the interest in realistic digital contents and examine their effectiveness, by implementing and applying VR around the science subject in middle schools. It organized each group of two for cooperative activities, in order to implement VR for 52 middle school students located at Y-county, who understood study contents and agreed to participate in the study. Then, it implemented and applied realistic digital contents regarding a change in the science geosphere and many kinds of forces, by extracting and designing them. As they implemented and applied VR around contents interest in science subject. VR assisted lessons made statistically significant differences in understanding and effectiveness of realistic digital contents. It will provide basic data used to cultivate future talents who can prepare for a change in the educational paradigms along with the fourth industrial revolution and adapt to the future knowledge-based society.
한상영,김재희 사단법인 미래융합기술연구학회 2022 아시아태평양융합연구교류논문지 Vol.8 No.8
This is a descriptive study to better understand the degree of nursing organizational culture, physical exhaustion, and nurses' quality of life, as well as the influence of nursing organizational culture on physical fatigue and quality of life. The questionnaire was carried out from November 1 to November 25, 2021, using a descriptive research approach. The study included 170 nurses who worked at a university hospital in W, Gangwon-do. Data were analyzed using t-test, ANOVA, Pearson correlation coefficient, and multiple regression with the SPSS/WIN 25.0 program. According to the findings of this study, nurses' quality of life showed a positive association with nursing organizational culture, whereas physical weariness showed a negative correlation. The sub-factor of nursing organizational culture that affects the physical fatigue and quality of life of nurses is hierarchical-oriented culture, which showed 67% explanatory power for physical fatigue, and acted as a variable that influenced 49% of the quality of life. Therefore, it is a need for a plan to improve the quality of care services that can improve the quality of life through mutual respect and organizational culture formation by all nurses through positive and developmental awareness of nursing managers.
한상영,최인성 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2
Single-cell nanoencapsulation (SCNE) demands cytocompatible materials and processes, to ensure the maintenance of cell viability, and prefers facile post-functionalization of the cytoprotective shells. This work proposes a hydrogen bonding-based layer-by-layer (LbL) self-assembly of eggshell membrane hydrolysate (ESMH) and tannic acid (TA) as a cytocompatible, and post-functionalizable, strategy applied to SCNE. As a proof-of-demonstration, individual Saccharomyces cerevisiae cells have been encapsulated, by the LbL multilayers of ESMH and TA, in an astonishingly cytocompatible manner (viability after SCNE: >99%). In addition to the cytoprotection capability, the ESMH/TA shell proves functionalizable, for example, including the bioinspired silicification for formation of organic/inorganic double-layered shells.