자료원별 암사망 통계치의 비교 분석

최소영,Choi, So-Young 한국생명보험의학회 2006 保險醫學會誌 Vol.25 No.-

연구배경 : 우리나라에서 암발생 및 암사망이 지속적으로 증가하면서 암관리에 대한 국가적인 관리가 시행되고 있으나, 이에 필수적인 암사망통계 자료 및 연구는 미흡한 실정이다. 따라서 자료원별로 암사망통계를 조사하고 비교 분석하고자 한다. 연구방법 : 1997년부터 2002넌까지 통계청의 사망원인통계연보, 보험개발원의 생명보험 사망원인통계자료를 수집하고 연령별, 성별, 암종류별로 비교 분석하였다. 연구결과 : 전체 암종류별 사망분율은 통계청 자료에서는 폐암이 가장 높았고 보험개발원 자료에서는 간암이 가장 높은 분포를 나타냈다. 남자의 경우 통계청과 보험개발원의 암종류별 사망분율은 모두 간암이 가장 높은 분포를 위암, 폐암 순이었다. 여자의 경우 두 자료원 모두 위암의 사망분물이 가장 높았으나, 통계청 자료에서는 간암, 유방암 순이었고, 보험개발원 자료에서는 유방암, 간암 순이었다. 결론 : 본 연구를 통해 사망자료원에 따라 암사망통계의 내용과 결과가 차이가 있으며, 이는 자료원의 목적과 성격에 차이가 있기 때문인 것으로 생각된다. 따라서, 이를 해석하고 이용하는데 자료원에 따라 충분한 검토와 주의가 요망된다.

국내 시범 생산 CFRP rod를 적용한 보 부재의 휨-전단 특성

최소영,김일순,최명성,양은익,Choi, So-Yoeng,Kim, Il-Sun,Choi, Myoung-Sung,Yang, Eun-Ik 한국구조물진단유지관리공학회 2022 한국구조물진단유지관리공학회 논문집 Vol.26 No.5

Replacement of FRP rod as steel reinforcement has been attracted significantly to prevent the degradation of the concrete structure due to corrosion. So, the technology development to extend the structure's service life by improving FRP properties has been proceeded worldwide. Accordingly, it is necessary to develop Korea's CFRP rod and CFRP grid, including the manufacturing techniques to improve the properties of high-strength and high-stiffness. Moreover, the research should be conducted to evaluate the structural behavior of the beams using the CFRP rod or grid. This study investigates the flexural and shear behavior of reinforced concrete beam using demonstrated CFRP rod as reinforcement according to the reinforcement ratio and shear span to depth ratio. From the results, when the reinforcement ratio is out of a specific range, it is seemed that the effect on performance improvement of the beam using CFRP rod is cancelled or not significant. Meanwhile, when the CFRP rod was used as reinforcement, the possibility of shear failure occurred, even steel stirrups were installed in the beam with CFRP rod as tensile reinforcement according to the Korean Design Standard. Therefore, when the CFRP rod is used as tensile reinforcement in a beam, it should be prepared that a specific limitation of reinforcement ratio and an investigation against shear failure. Also, the ductility of the beam using the CFRP rod is determined by the deformation energy evaluation method. So, the ductility should be investigated by applying the deformation energy evaluation method that reflects the structural behavior of the beam.

강원도 지역 가임기 여성의 분만서비스 접근성 분석

최소영,이광수,Choi, Soyoung,Lee, Kwang-Soo 한국보건행정학회 2017 보건행정학회지 Vol.27 No.3

Background: This study purposed to analyze the spatial accessibility of women in childbearing age to the healthcare organizations (HCOs) providing delivery services in Gangwon-do. Methods: Network analysis was applied to assess the spatial accessibility based on the travel time and road travel distance. Travel time and travel distance were measured between the location of HCOs and the centroid of the smallest administrative areas, eup, myeon, and dong in Gangwon-do. Korean Transport Database Center provided road network GIS (Geographic Information System) Database in 2015 and it was used to build the network dataset. Two types of network analysis, service area analysis and origin-destination (OD)-cost matrix analysis, applied to the created network dataset. Service area analysis defined all-accessible areas that are within a specified time, and OD-cost matrix analysis measured the least-cost paths from the HCOs to the centroids. The visualization of the number of the HCOs and the number of women in childbearing age on the Ganwon-do map and network analysis were performed with ArcGIS ver. 10.0 (ESRI, Redlands, CA, USA). Results: Twenty HCOs were providing delivery services in Gangwon-do in 2016. Over 50% of the women in childbearing age were aged more than 35 years. Service area analysis found that 89.56% of Gangwon-do area took less than 60 minutes to reach any types of HCOs. For tertiary hospitals, about 74.37% of Gangwon-do area took more than 60 minutes. Except Wonju-si and Hoengseong-gun, other regions took more than 60 minutes to reach the tertiary hospital. Especially, Goseong-gun, Donghae-si, Samcheok-si, Sokcho-si, Yanggu-gun, Cheorwon-gun, and Taebaek-si took more than 100 minutes to the tertiary hospital. Conclusion: This study provided that the accessibility toward the tertiary hospital was limited and it may cause problems in high-risk delivery patients such as over 35 years. Health policy makers will need to handle the obstetric accessibility issues in Gangwon-do.

월간 <디자인> 잡지 구독 서비스의 사용자 경험 연구

최소영,김승인,Choi, So-Yeong,Kim, Seung-In 한국디지털정책학회 2021 디지털융복합연구 Vol.19 No.8

본 연구는 디자인을 공부하는 학생 사용자, 혹은 디자이너로 일하고 있는 사용자를 중심으로 월간 <디자인> 잡지 구독 서비스의 사용자 경험에 관한 연구이다. 잡지 산업의 매출액은 2012년 이후 지속적으로 감소하고 있으며, 국내에서 발행되는 일부 잡지는 폐간 혹은 영구 휴간 절차를 밟았다. 이 연구는 잡지 매출액의 가장 큰 부분을 차지하는 잡지 판매 수입을 증대하기 위해 월간 <디자인>을 중점으로 잡지 구독 서비스의 사용자 경험을 측정하였다. 이를 위해 구독자와 비구독자 대상으로 설문조사 및 심층 인터뷰를 실시하여 개선사항을 제안하였다. 이 연구는 사용자 경험에 초점을 두었으며, 향후 잡지 구독 서비스 연구에 참고자료로 활용할 것으로 기대한다. This study researched the user experience of the monthly <DESIGN> magazine subscription service, focusing on design students and designers. The revenue of magazine industry has been declined since 2012 and some magazines stop publishing or cease to publish. That is why this studied the user experience of magazine subscription services of monthly <DESIGN> to increase magazine sales revenue, the largest portion of whole revenue. A survey and in-depth interviews with subscribers and non-subscribers was conducted to suggest improvements for the monthly <DESIGN>. Since this study focused on user experience of magazine subscription, it could be a future reference for studying magazine subscription service.

언더라이팅시 흔하게 접하는 심전도 소견과 위험 평가

최소영,Choi, So-Young 한국생명보험의학회 2007 保險醫學會誌 Vol.26 No.-

ECG is included in certain medical examinations of insurance application, ECG has low specificity and sensitivity. So ECG is not usually used to diagnose specific diseases. But, ECG is not invasive and costs low. So ECG is usually used in underwriting. Actually in underwriting we meet various ECG patterns and diagnosises. Understanding of various ECG patterns is different between insurance medicine and clinical medicine. So We have to learn various ECG patterns and effects on mortality and morbidity. First considerations of ECG readings are age, sex, blood pressure, family history, smoking historyalcohol history and hyperlipidemia. These are predictors for possibility of disease. Also it is important to review recording ECG with proper skill. In this review I consider several ECG diagnosises that we meet frequently, which is, LVH, RVH, ST abnormalities, LBBS, RBBB, A-B blocks, several kinds of arrhythmia. We have to consider long term mortalities and morbidities of specific ECG patterns although applicants have no symptom and sign. And then we have to make underwriting manual according to specific ECG diagnosises and patterns and underwrite precisely ECG patterns according to insurance products. Nowadays coronary heart disease and other heart diseases are increasing in Korea. So we have to learn various ECG patterns and research mortalities and morbidities of abnormal ECG patterns. Also we have to apply to more broad, precise underwriting skills about ECG patterns and diagnosises.

자궁경부암 방사선치료 시 직장가스 용적 변화에 따른 선량 비교 평가 - Phantom Study

최소영,김태원,김민수,송흥권,윤인하,백금문,Choi, So Young,Kim, Tae Won,Kim, Min Su,Song, Heung Kwon,Yoon, In Ha,Back, Geum Mun 대한방사선치료학회 2021 대한방사선치료학회지 Vol.33 No.-

목 적: 본 연구에서는 자궁경부암 방사선치료 시 전산화치료계획에 없던 직장 내 가스 용적 변화에 따른 선량변화를 비교 평가하고자 한다. 대상 및 방법: 인체모형 팬텀(Anderson Research Laboratories Inc, RANDO^TM phantom, USA)의 전산화 단층촬영 영상에 전산화치료계획시스템(Eclipse^TM Treatment Planning System, Varian, Palo Alto, version 15.6, USA)으로 9개의 필드를 이용한 정적 세기조절방사선치료계획(Static Intensity Modulated Radiation Therapy, S-IMRT)과 Full arc로 두 방향의 체적변조회전방사선치료계획(Volumetric Modulated Arc Therapy, VMAT)을 수립하였다. 임의의 가스 변수는 0.5 cm 단위로 2.0 cm까지 변화를 주어 계획표적체적(Planning Target Volume, PTV)에 포함될 수 있도록 하였다. 표적에 대한 처방선량지수(Conformity Index, CI), 선량균질지수(Homogeneity Index, HI), PTV D_max를 구하였고, 손상위험장기(Organ At Risk, OAR)에 대한 최소선량(Minimum Dose, D_min)과 평균선량((Mean Dose, D_mean), 최대선량(Maximum Dose, D_max)을 계산하여 비교하였다. T-검정을 실시하여 p-value를 구했으며 유의수준은 0.05로 설정하였다. 결 과: S-IMRT와 VMAT의 HI 결정계수(R²)는 0.9423, 0.8223으로 상관관계가 비교적 명확하였고, PTV D_max 결과 임의의 가스 용적이 커질수록 최대 2.8%까지 증가하는 것으로 나타났다. OAR의 경우 두 전산화치료계획 모두 방광에서 유의한 차이가 없었고, 직장의 경우 +1.0 cm 이상의 가스 용적에서 두 전산화치료계획 모두 D_mean 700 cGy 이상의 유의한 선량 차이가 나타났다. 방광의 D_mean을 제외한 모든 값에서 p-value 0.05 이하로 통계적인 유의한 차이를 확인하였다. 결 론: 기준 전산화치료계획에 없던 가스 발생 시 가스 용적 크기가 커질수록 PTV의 선량 변화와 직장에 전달되는 선량이 증가하였다. 방사선치료 진행 시 직장 가스의 용적이 클 경우 발생 할 수 있는 선량 전달 오류를 최소화하기 위한 노력이 반드시 필요한 것으로 판단되었다. 향후 가스 용적의 다양한 크기와 위치를 변수로 설정하여 추가적인 연구가 진행되어진다면 유익한 평가가 이루어 질 수 있을 것으로 사료된다. Purpose: The purpose of this study is to compare and evaluate the dose change according to the gas volume variations in the rectum, which was not included in the treatment plan during radiation therapy for cervical cancer. Materials and methods: Static Intensity Modulated Radiation Therapy (S-IMRT) using a 9-field and Volumetric Modulated Arc Therapy (VMAT) using 2 full-arcs were established with treatment planning system on Computed Tomography images of a human phantom. Random gas parameters were included in the Planning Target Volume(PTV) with a maximum change of 2.0 cm in increments of 0.5 cm. Then, the Conformity Index (CI), Homogeneity Index (HI) and PTV D_max for the target volume were calculated, and the minimum dose (D_min), mean dose (D_mean) and Maximum Dose (D_max) were calculated and compared for OAR(organs at risk). For statistical analysis, T-test was performed to obtain a p-value, where the significance level was set to 0.05. Result: The HI coefficients of determination(R²) of S-IMRT and VMAT were 0.9423 and 0.8223, respectively, indicating a relatively clear correlation, and PTV D_max was found to increase up to 2.8% as the volume of a given gas parameter increased. In case of OAR evaluation, the dose in the bladder did not change with gas volume while a significant dose difference of more than D_mean 700 cGy was confirmed in rectum using both treatment plans at gas volumes of 1.0 cm or more. In all values except for D_mean of bladder, p-value was less than 0.05, confirming a statistically significant difference. Conclusion: In the case of gas generation not considered in the reference treatment plan, as the amount of gas increased, the dose difference at PTV and the dose delivered to the rectum increased. Therefore, during radiation therapy, it is necessary to make efforts to minimize the dose transmission error caused by a large amount of gas volumes in the rectum. Further studies will be necessary to evaluate dose transmission by not only varying the gas volume but also where the gas was located in the treatment field.

증례점검 사례를 통한 다양한 언더라이팅 접근 방향 모색

최소영,Choi, So-Yung 한국생명보험의학회 2008 保險醫學會誌 Vol.27 No.1

I have taught various case audit underwriting methods to underwriters for many years. Underwriting requires specialized medical knowledge and experience of comprehensive individual risk analysis. Decisions in individualized underwriting depend on the insurance company's management philosophy and vision, marketing strategies, culture, product line etc. They also depend on the information acquired through proposal forms, inspection reports, laboratory results and disclosures. Underwriters match this acquired information to each insurance product, search appropriate medical resources, assess the probabilities of future claims, and decide what, if any, further medical information should be gathered. Sources include doctors' reports, medical records, biopsies, blood and urine tests, CT, MRI, Holter monitoring, sonography etc. Insurance medical directors help and teach underwriters to analyze individual medical risks and make effective.

집중호우 사상을 고려한 Huff의 4분위법 개선방안

최소영,주경원,신홍준,허준행,Choi, Soyung,Joo, Kyungwon,Shin, Hongjoon,Heo, Jun-Haeng 한국수자원학회 2014 한국수자원학회논문집 Vol.47 No.11

수공구조물을 설계함에 있어 설계우량주상도를 결정하기 위해 설계강우량을 시간분포시키는 방법은 매우 중요하다. 우리나라에서 널리 쓰이는 Huff 방법의 경우 MOCT(2000), MOLTMA (2011)에서 적용성을 높여왔으나, 기존 Huff (1967) 방법과 똑같은 기각기준으로 강우총량 1 inch (25.4mm)를 제시하고 있다. 따라서 본 연구에서는 Huff 방법 적용시 자료 기각기준을 집중호우기준에 따라 극치사상만을 분석하는 시간분포방법을 제안하였고, 이를 실제유역에 적용시켜 강우-유출모형을 통한 검증을 실시하였으며 목적함수 비교를 통해 실제유역의 적용성을 확인하였다. 그 결과 첨두유출량의 과소산정 문제를 보완하여 실제 첨두유출량에 더 가까운 유출수문곡선을 제시함으로써 수공구조물 설계의 안정성을 높일 수 있을 것으로 판단된다. When designing hydraulic structures, the chosen method of time distribution in a hyetograph is highly significant. There are several methods used for measuring time distribution. In the case of Huff (1967), which is widely used in Korea, the Ministry of Construction and Transportation (MOCT, 2000), and the Ministry of Land, Transport and Maritime Affairs (MOLTMA, 2011) have long been increasing their use of this method. The MOLTMA uses the conventional Huff method's measurement of 1 inch (25.4 mm) as the threshold. Many researchers have pointed out that this method often leads to underestimation, because of the excessive flatness. Therefore, for this study, a new time distribution method was developed to analyze only extreme rainfall events-those over the standard of severe rainstorms (that is, more than 30 mm per hour or 80 mm per day)-and that was verified using a rainfall-runoff model and applying it to a real basin.

멜라닌 세포에서 홍차 열수추출물의 멜라닌 합성 저해능과 작용기전

최소영,김영철,장병수,Choi, So-Young,Kim, Young-Chul,Chang, Byung-Soo 한국현미경학회 2011 Applied microscopy Vol.41 No.3

홍차 열수추출물의 멜라닌 합성 저해능과 작용기전을 알아보기 위해 in vitro 실험으로 항산화능을 확인한 후, melan-a 세포를 사용하여 멜라닌 합성 저해능, tyrosinase 활성 저해능 및 발현저해능 등에 대한 실험을 실시하여 다음과 같은 결과를 얻었다.(1) 항산화능 실험에서 홍차 열수추출물의 총 폴리페놀 및 플라보노이드 함량은 각각 102, 87 mg/g으로 양성대조군인 알부틴(25, 11 mg/g)보다 높았고, 전자공여능 역시 800 ${\mu}g$/mL에서 82%로 알부틴(48%)보다 높았다. (2) Melan-a 세포 실험에서 홍차 열수추출물은 수지상돌기의 발달과 멜라닌 생합성을 효과적으로 저해하였고, 멜라닌 합성 저해능과 tyrosinase 활성 저해능이 알부틴보다 유의하게 (p<0.001) 높았다. (3) Tyrosinase 단백질 발현 저해능 실험에서 알부틴은 발현에 유의한 영향을 미치지 않은 반면, 홍차 열수추출물은 발현을 유의하게 (p<0.001) 저해하였다. (4) 유전자 발현 저해능 실험에서 알부틴과 홍차 열수추출물 모두 tyrosinase, TRP-1과 TRP-2의 mRNA 발현에 영향을 미치지 않았다. 본 연구를 통하여, 홍차 열수추출물은 우수한 항산화능과 함께 멜라닌 합성 저해능을 확인하였으며, 이는 tyrosinase의 생합성을 저해시키기 보다는 tyrosinase 단백질 발현량을 줄이고 tyrosinase 활성을 감소시킴으로써 멜라닌 합성을 저해시키는 것으로 사료된다. To evaluate the whitening effect of Camellia sinensis water extract (CSWE), CSWE was treated to melan-a cells. Total polyphenol contents and flavonoid contents of CSWE were 102 mg/g and 87 mg/g, respectively. The electron-donating ability of CSWE revealed a dose-dependent response, showing the excellent ability of 82% at 800 ${\mu}g$/mL, and which was higher than the arbutin (48%). The CSWE significantly (p<0.001) suppressed the melanin synthesis and the development of melanocyte dendrites was inhibited in a dose-dependent manner. The CSWE significantly (p<0.001) inhibited both intra-cellular and cell-extracted tyrosinase activities. And inhibitory efficacies of CSWE on both melanin synthesis and tyrosinase activity were significantly (p<0.001) higher than the arbutin. The tyrosinase protein expression was not influenced by arbutin treatment. However, CSWE treatment significantly (p<0.001) reduced it. Both arbutin and CSWE treatment did not influence on mRNA expressions of tyrosinase, tyrosinase-related protein-1 and tyrosinase related protein-2.

라텍스와 광물질 첨가제가 레미콘LMC (Remicon Latex Modified Concrete) 내구성에 미치는 영향

최소영,최윤석,허형석,양은익,Choi, So Yeong,Choi, Yoon Suk,Heo, Hyeong Seok,Yang, Eun Ik 대한토목학회 2014 대한토목학회논문집 Vol.34 No.6

라텍스 첨가는 콘크리트의 압축 및 휨거동, 부착강도, 염화물 저항성 및 동결융해 저항성의 향상을 유도할 수 있는 것으로 알려져 있다. 이러한 이유로, 기존 포장 콘크리트 보다 LMC에 관한 많은 연구가 진행되고 있다. 그러나 소음이나 공사비용등을 비롯한 문제점 때문에 LMC의 성능을 향상시키기 위한 새로운 방법들이 시도되고 있으며, 최근, LMC의 문제점을 해결하고자 레미콘 LMC가 개발되었다. 본 연구에서는 레미콘 LMC의 내구성을 라텍스와 광물질 첨가제의 혼입 비율에 따라 비교하였다. 실험결과, 레미콘LMC는 압축강도, 휨강도, 부착강도가 한국 도로공사 전문 시방서 기준을 만족하였으며, 레미콘LMC의 내구성은 우수한 것으로 나타났다. 또한, 레미콘LMC에 라텍스를 8% 이상 혼입해야 기존 LMC와 동등 이상의 내구성을 확보하는 것으로 나타났다. It is well known that latex modification can lead to enhancement compressive and flexural performance, tensile bond strength, chloride penetration resistance and freezing-thawing resistance for concrete. For these, many studies for LMC pavement have been widely conducted more than those for conventional pavement concrete. However, due to several problems such as noise and construction cost, new approaches for LMC have been executed to improve the performance of LMC. Recently, Remicon LMC was developed in order to solve the problems of LMC. In this study, the durability of Remcion LMC was compared with latex and mineral additive mixing ratio. From the results, when latex and mineral additive were mixed in Remicon LMC, compressive, flexural and bond strength were satisfied with Korea Highway Construction Guide Specification. And, it showed that the qualitative effect of latex and mineral additive mixing ratio on the durability of Remicon LMC was investigated experimentally. Also, the latex mixed in Remicon LMC must be at least 8%, in order to ensure the durability equivalent or higher than conventional LMC.