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중풍 임상 연구를 위한 항목 선정 및 정보관리 프로그램 개발
문진석,최선미,조기호,윤유식,Moon, Jin-Seok,Choi, Sun-Mi,Cho, Ki-Ho,Yoon, Yoo-Sik 한국한의학연구원 2005 한국한의학연구원논문집 Vol.11 No.1
In a field of oriental medicine, it is necessary to collect systemically clinical data and integrate. Input data items was decided, then categorized by the modules through discussion of the institute and hospitals. Items are information of patient, history, aspects of occurrence, pattern identification, prescriptions of herbal medicine, the results of biochemical serum examination, blood cell count, urine analysis, CT, MRI, Chest PA, EKG etc. Factors in oriental medicine are Sasang constitution, Stroke-Pattern-Identification(china), differentiation of cold and heat syndrome. This tool was constructed by using Microsoft-Access 2000 and Microsoft Visual Basic 6.0. Furthermore this web-based system could be applied to multi-center clinical investigation.
윤유식,김선형,최선미,문진석,강동근,김영,안영복,이종철,정우진,Yoon, Yoo-Sik,Kim, Sun-Hyoung,Choi, Sun-Mi,Moon, Jin-Seok,Kang, Dong-Kun,Kim, Young,Ahn, Young-Bok,Lee, Jong-Cheol,Jung, Woo-Jin 한국한의학연구원 2003 한국한의학연구원논문집 Vol.9 No.2
The goal of this study is construction and efficacy evaluation of MPC-25 (Magnetic Pain Control-25), a medical device using magnetic stimulation. MPC-25 consists of a main body containing power supply and control module and a bed containing magnetic core and coil. In distinction from electric pain control medical devices, magnetic pain control system is non-contact, so the patients need not take off their clothes to be treated. High amplitude current pulses are applied to a magnetic coil and induce time varying magnetic field generating eddy current in a conductor like human body. Clinical efficacy test was performed in patients suffering from musculoskeletal pain of lumbar, shoulder and joint. Degree of pain before and after treatment for 30 minutes was compared using Visual Analogous Scale. As a result, 14 cases out of 20 showed decreased pain perception, so the rate of efficacy is 70%. Reduction of pain perception was statistically significant (P=0.001 by Wilcoxon Signed Rank Test).
UCP-2, 3 단일염기다형성이 한국인 여성의 체중감량에 미치는 영향
심우진 ( Woo Jin Shim ),문진석 ( Jin Seok Moon ),최선미 ( Sun Mi Choi ),신승우 ( Seung Uoo Shin ),김길수 ( Kil Soo Kim ) 한방비만학회 2006 한방비만학회지 Vol.6 No.2
This study was conducted to investigate the effects of Uncoupling protein (UCP) polymorphisms on weight loss. We analyzed associations between polymorphisms of UCP-2, 3 and changes in percentage of obesity phenotypes (Body mass index and percent body fat) after treatment. Materials and Methods: A total of 207 Korean women (BMI over 25) were recruited from the obesity clinic in Kirin Oriental Medical Hospital (Seoul, Korea). All patients were treated with a very low calorie diet and oriental medical therapy for one month. The effect of UCP polymorphisms on changes in obesity-phenotypes were analyzed. For the genotyping of a single nucleotide polymorphism (SNPs), genomic DNA from each subject was extracted from whole blood and genotyped using the TaqMan Method. Associations between changes in percentage of obesity phenotypes (BMI and percent body fat) and UCP polymorphisms were analyzed using age-adjusted general linear model. Results and Conclusions: In this study, AG, GG type of UCP-2 -866A>G, CC, CT type of UCP-2 +4787C>T, CG, GG type of UCP-3 +2564C>G, AG, GG type of UCP-3 +3106A>G, and TC, CC type of UCP-3 +4589T>C played a role as a resistance gene to weight loss.
Magnetocardiography(MCG)를 이용한 심병증의 진단에 관한 임상연구
송낙근,류연희,문진석,안규석,최선미,Song, Nak-Kun,Ryu, Yeon-Hee,Moon, Jin-Suk,Ahn, Kyoo-Seok,Choi, Sun-Mi 한국한의학연구원 2004 한국한의학연구원논문집 Vol.10 No.2
The aim of this study is to confirm clinical usefulness of MCG data by analyzing korea medical results of heart disease patients. We used the Heart Disease Questionnaire which asks for Qi deficiency-pattern, Blood deficiency-pattern, Yin deficiency-pattern, Yang deficiency-pattern, Qi stasis-pattern, Blood stasis-pattern, Heart heat-pattern, Phlegm-pattern. Magnetocardiography(MCG) is the measurement of magnetic fields emitted by the human heart from small currents by electrically active cells of the heart muscle. Comparing the MCG results and korea medical diagnosis, we showed clinical usefulness of MCG results and korea medical diagnosis.
한방임상사용 의료기기의 실태 조사를 통한 개선방향 제시
문진석,김종열,류연희,송낙근,김혁주,이정림,이재원,최선미,Moon, Jin-Seok,Kim, Jong-Yeol,Ryu, Yeon-Hee,Song, Nak-Kun,Kim, Hyeog-Ju,Lee, Jeong-Rim,Lee, Jae-Won,Choi, Sun-Mi 한국한의학연구원 2005 한국한의학연구원논문집 Vol.11 No.1
We conduct a survey of actual condition of medical devices in korea traditional medicine on 157 oriental medicine doctors and 183 manufacturers. The 61% percent of doctors indicate the trouble in use of medical devices which is applied to korea traditional medicine. The manufacturers replied that devices have a problem with diagnosis(53%) and treatment(36%). To overcome these problems, it is necessary to develop devices based on the study of basic oriental medicine and the reliable clinical research. This study contributes the improvement of quality and the revision of rules on medical devices.
문진석,강병갑,강경원,심우진,신미숙,최선미,Moon, Jin-Seok,Kang, Byung-Kab,Kang, Kyung-Won,Shin, Woo-Jin,Shin, Mi-Sook,Choi, Sun-Mi 한방비만학회 2008 한방비만학회지 Vol.8 No.1
Objectives We have investigated a questionnaire on syndrome differentiation pertaining to obesity. To calculate data from this questionnaire, we can simply sum up the degree of symptoms. However, this does not reflect the difference in contribution of syndrome differentiation. In order to improve the level of precision of this questionnaire, we gather the weight of each symptom from experts and apply them to overweight persons. Method Nine Experts from The Society of Korean Medicine for Obesity Research nominated weights for the symptoms. We created a program based on weight survey results and applied to 1487 overweight persons and 26 oriental medical doctors. The concordance rate between the result obtained from the oriental medical doctors and that obtained using three methods was analyzed. Results 1. The reliability of this questionnaire is very high (Cronbach' ${\alpha}$=0.963). 2. The concordance level between diagnosis by oriental medical doctors and the result of general calculation is 0.347, between diagnosis by oriental medical doctors and the result of weighted calculation by syndrome differentiation is 0.362, between diagnosis by oriental medical doctors and the result of weighted calculation by symptoms is 0.1. Conclusions Weighted calculation by syndrome differentiation is relative more appropriate among three methods studied.
원저 : 한방비만변증 설문지를 바탕으로 증상 척도에 따른 변증진단 비교
강경원 ( Kyung Won Kang ),문진석 ( Jin Seok Moon ),강병갑 ( Byung Gab Kang ),김보영 ( Bo Young Kim ),신미숙 ( Mi Sook Shin ),최선미 ( Sun Mi Choi ) 한방비만학회 2009 한방비만학회지 Vol.9 No.1
The study was to investigate the distribution for the diagnosis of pattern identification based on obesity pattern identification questionnaire and agreement rate between the diagnosis of pattern identification based on obesity pattern identification questionnaire and the clinical diagnosis of pattern identification by medical specialist. The distribution for the diagnosis of pattern identification based on obesity pattern identification questionnaire was shown in order of stagnation of liver Gi, retention of undigested food, deficiency of Yang at scale of 5, 3, 2 score and the diagnosis rate of single pattern identification at scale of 5, 3, 2 score was 89.96%, 79.33%, 54.64%, respectively. the agreement rate between the diagnosis of pattern identification based on obesity pattern identification questionnaire and the clinical diagnosis of pattern identification by medical specialist was 0.1013. Therefore, the complementary management in CRF questionnaires with consultation from experts and the study for score difference of pattern identification will improve the accuracy and agreement rate, which will be helpful for pattern identification of obesity by clinical experts.
원저 : 폐경전 및 갱년기 과체중 한국 성인 여성의 변증 지표 차이에 대한 연구
정원석 ( Won Suk Chung ),황미자 ( Mi Ja Hwang ),이아라 ( A Ra Lee ),문진석 ( Mi Yeon Song ),최선미 ( Jin Seok Moon ),송미연 ( Sun Mi Choi ) 한방비만학회 2008 한방비만학회지 Vol.8 No.2
Objectives The aim of the study was to investigate the difference between pattern identification of premenopausal(n=39) and climacteric(n=40) korean obese and overweight women using Syndrome Differentiation Questionaire. Methods 39 premenopausal obese women(BMI≥25kg/m2) and 40 climacteric overweight and obese women(BMI≥23kg/m2) were recruited from October 2007 to March 2008 in Seoul, Korea. Subjects who had other disease were rejected. Basic anthropometry and body composition were measured. Every subjects were given and filled out the Syndrome Differentiation Questionaire, and we analyzed that using Fisher`s exact test. Results 1. Premenopausal women showed high frequency of food accumulation pattern(43.6%), but in climacteric women, liver qi depression pattern was frequent(57.5%, p=0.021). 2. In weighted Syndrome Differentiation Questionaire score, Premenopausal women showed high frequency of food accumulation pattern(43.6%), but in climacteric women, liver qi depression pattern was frequent(47.5%, p=0.004). 3. There were no correlation between anthropometry and scores of the each patterns. Conclusions In this study, we can find out that the dietary factors play major roles in obesity of premenopausal women and emotional factors in obese climacteric women in the view of oriental pattern identification diagnosis. But it seemed that there lacked of consideration that reflected the degree of obesity in this Syndrome Differentiation Questionaire.