척추 측만증의 보존적 치료에 관한 최신 지견 - PubMed 검색을 위주로 2008년 이후 -

조성우,이승연,Cho, Sung Woo,Lee, Seung Yeon 대한한방소아과학회 2013 대한한방소아과학회지 Vol.27 No.1

Objectives Scoliosis is that spine's arrangement was changed to be curved. Mostly scoliosis was found at childhood and recently rate of scoliosis is increasing. Causes of scoliosis were very various, but the patients are due to idiopathic reasons. Scoliosis was treated by conservative treatment or surgery treatment. If scoliosis is diagnosed early enough, it can be treated with conservative treatment. Methods We are searching PubMed by keywords and found 47 theses complied with requirements. Results Studies of conservative treatment of Scoliosis were active. Conservative treatments are considered before surgery treatment and there was a set guideline of conservative treatment. Also, there were several studies about effectiveness of conservative treatment and quality of life, mental stress. Studies about various kinds of conservative treatment were found as well. There were brief studies about introduction of new brace, effectiveness of several braces, and case studies. Conclusions Conservative treatment is very effective choice before surgery treatment at Scoliosis patient.

사람 혈소판에서 분리한 Transforming Growth Factor - β가 초회 배양된 Mesangial 세포의 복제 및 Collagen 합성에 미치는 영향

조성우,박수길,김금이,이희봉,이재담 ( Sung Woo Cho,Su Kil Park,Geum Yi Kim,Hee Bong Lee,Jae Dam Lee ) 생화학분자생물학회 1992 BMB Reports Vol.25 No.3

The effect of TGF-β on cell replication and collagen synthesis in primarily cultured mesangial cells from rats was studied in vitro. The TGF-β was purified from human platelets by acidic ethanol extraction and gel filtration with FPLC. The effect of TGF-β on the DNA synthesis and the collagen synthesis in mesangial cells depended on both TGF-β concentration and cell density in monolayer culture. Concentrations of TGF-β ranging from 0.1∼15 ng/ml were evaluated for their effects upon DNA synthesis. In confluent cells, when compared to the growth rate in standard medium, TGF-β concentrations in the range 0.1∼15 ng/ml reduced a cell proliferation up to 35%, suggesting inhibition of cell division. The effect of TGF-β on collagen synthesis in mesangial cells was biphasic. In confluent cells, the addition of TGF-β induced a 2-fold increase in the production of collagen when compared with cells grown in standard medium. The maximal effect of TGF-β occurred at 0.5 ng/ml. At higher concentrations there was a decrease in the action of TGF-β with the effects on collagen production. In subconfluent cells, however, TGF-β showed no significant effects on the DNA synthesis and the collagen synthesis at all concentrations. These results support that TGF-β may play an important role as a multifunctional regulator in the pathogenesis of glomerulosclerosis. v

교통사고 환자에 대한 진단 및 치료의 경향성 연구 -국내에서 발표된 학위지 밀 학술논문을 중심으로-

조성우,강연경,장동호,이인선,Cho, Sung-Woo,Kang, Yeon-Kyeong,Chang, Dong-Ho,Lee, In-Seon 척추신경추나의학회 2009 척추신경추나의학회지 Vol.4 No.2

Objectives : The purpose of this study is finding tendencies of diagnosis and treatment of the traffic accidental patients. Methods : We reviewed and analyzed all theses published by Korean research institution. And these theses were classified by year, field of study, reviewed by focusing on diagnosis and evaluation, treatment type. Results : 1. 72 articles were published since 1993. 2. Classified by the major field of study, the korean academy of oriental rehabilitation medicine accounted for 33 papers. 3. 7-Zone-Diagnostic system and Minnesota Multiphasic Personality Inventory were studied mostly. 4. To add pharmacopuncture or chuna treatments are effective. 5. Traffic accidental patients get satisfaction about Oriental medicine therapy but methods of medical treatment are restrictively. Conclusions : Oriental medicine treatment is the effective way to cure traffic accidental sequela, but we need further studies.

한방병원에 입원한 교통사고 환자 34명에 대한 임상적 고찰

조성우,고경훈,남정훈,김봉현,이인선,Cho, Sung-Woo,Go, Kyung-Hoon,Nam, Jung-Hun,Kim, Bong-Hyun,Lee, In-Seon 척추신경추나의학회 2006 척추신경추나의학회지 Vol.1 No.2

Objective: The purpose of this study is finding tendencies admission patients to orient medical hospital due to Traffic Accident. Method: We studied 34 cases who were admitted in Dong-eui University Oriental Hospital from 1st, December, 2003 to the 30st, May, 2005. And we came to some conclusion about clinical tendencies as follows. Results and Conclusions: 1. Women had occupied more than men, And 10 persons in 30th were the most distribution of age. 2. Most patients used western medical hospital as primary hospital and after several days they started to search for orient medical treatments. 3. In the diagnosis through radiological test, cervical spine sprain was most(19 cases, 55.6%). The others were lumbar spine sprain(14 cases, 41.2%), fracture of other bone{4 cases, 11.8%), fracture of spine(3 cases, 8.8%), Intercranial hemorrhage(3 cases, 8.8%). 4. In chief complaint, low back pain was most(19 cases, 55.9%), The others were neck stiffness(17 cases, 50.0%), headache(13 cases, 38.2%), lower limb pain(9 cases, 26.5%). 5. Simple Disease had higher than complex disese at effective rate. 6. Both $43{\sim}60$ days admission and $15{\sim}21$ days admission were the best effective. $8{\sim}14$ days admission was next effective. 7. Early visit made more effective.

롤투롤 스퍼터 시스템을 이용하여 PET 기판위에 성막 시킨 ITO 박막의 특성 연구

조성우,최광혁,배정혁,문종민,정진아,정순욱,박노진,김한기,Cho, Sung-Woo,Choi, Kwang-Hyuk,Bae, Jung-Hyeok,Moon, Jong-Min,Jeong, Jin-A,Jeong, Soon-Wook,Park, No-Jin,Kim, Han-Ki 한국재료학회 2008 한국재료학회지 Vol.18 No.1

The electrical, optical, structural and surface properties of an indium tin oxide (ITO) film grown on a flexible PET substrate using a specially designed roll-to-roll (R2R) sputtering system as a function of the DC power, $Ar/O_2$ flow ratio, and rolling speed is reported. It was observed that both the electrical and optical properties of the ITO film on the PET substrate were critically dependent on the $Ar/O_2$ flow ratio. In addition, x-ray diffraction examination results showed that the structure of the ITO film on the PET substrate was an amorphous structure regardless of the DC power and the $Ar/O_2$ flow ratio due to a low substrate temperature, which was maintained constant by a main cooling drum. Under optimized conditions, ITO film with resistivity of $6.44{\times}10^{-4}{\Omega}-cm$ and transparency of 86% were obtained, even when prepared at room temperature. Furthermore, bending test results exhibited that R2R-grown ITO film had good flexibility which would be applicable to flexible displays and solar cells.

단순 연소법으로 합성한 LiNi_0.5Mn_0.3Co_0.2O₂ 양극 활물질의 구조 분석 및 전기화학적 특성 연구

조성우,주정훈,류성현,류광선,Cho, Sung-Woo,Ju, Jeong-Hun,Ryu, Seong-Hyeon,Ryu, Kawng-Sun 한국전기화학회 2010 한국전기화학회지 Vol.13 No.4

$LiNi_{0.5}Mn_{0.3}Co_{0.2}O_2$의 리튬이온 이차전지 양극 물질로의 특성을 연구하기 위해서 단순 연소합성법을 이용하여 합성했다. 합성된 물질의 구조적 특징을 분석하기 위하여 X-선 회절분석(XRD)과 주사전자현미경 (FE-SEM)을 측정하였다. X-선 회절분석을 통하여 합성된 $LiNi_{0.5}Mn_{0.3}Co_{0.2}O_2$시료가 육방정계 층상구조가 형성된 것을 확인하였다. FE-SEM을 통해 측정한 결과 $LiNi_{0.5}Mn_{0.3}Co_{0.2}O_2$ 입자는 일정한 형태를 가지지 않았으며 크기는 대략 100~300 nm의 크기임을 확인할 수 있었다. 그리고 전기화학적 특성을 측정하기 위하여 충 방전 용량 측정과 CV(Cyclic Voltammetry)를 측정하였다. 2.8 V에서 4.3 V까지 충 방전 용량을 측정한 결과 ~162 mAh/g의 초기 방전 용량을 가졌다. $LiNi_{0.5}Mn_{0.3}Co_{0.2}O_2$ active material was prepared by simple-combustion method and investigated as the cathode material for li-ion battery. The structural characterization was analyzed by X-ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM), respectively. The XRD patterns of $LiNi_{0.5}Mn_{0.3}Co_{0.2}O_2$ sample was indicated a phase of layered hexagonal structure. The size of particles has not uniform diameters ranging from 100 to 300 nm. The electrochemical performance of the $LiNi_{0.5}Mn_{0.3}Co_{0.2}O_2$ was measured by Cyclic Voltammetry and galvanostatics. The $LiNi_{0.5}Mn_{0.3}Co_{0.2}O_2$ shows the discharge capacity of ~162 mAh/g in the range of 2.8 to 4.3 V at the first cycle.

Effects of Human Platelet Transforming Growth Factor-$\beta$ on Replication and Collagen Synthesis in Primarily Cultured Mesangial Cell

조성우,박수길,김금이,이희봉,이재담,Cho, Sung-Woo,Park, Su-Kil,Kim, Geum-Yi,Lee, Hee-Bong,Lee, Jae-Dam 생화학분자생물학회 1992 한국생화학회지 Vol.25 No.3

쥐의 mesangial 세포를 초회 배양하여 Transforming Growth Factor-$\beta$(TGF-$\beta$)가 세포의 복제 및 collagen 합성에 미치는 영향을 조사하였다. TGF-$\beta$는 사람 혈소판에서 산성 에탄올 침전법 및 FPLC를 이용한 젤 크로마토그래피의 방법으로 정제되었다. TGF-$\beta$가 mesangial 세포를 복제 및 collagen 합성에 미치는 영향은 TGF-$\beta$ 농도와 세포의 밀도에 따라 달라졌다. Confluent 세포의 경우 0.1~15 ng/ml의 농도에서 TGF-$\beta$는 mesangial 세포의 복제를 35%까지 감소시켰다. Collagen 합성은 0.5 ng/ml의 TGF-$\beta$ 농도에서는 2배로 증가되었으나 그 이상의 농도에서는 감소하기 시작하는 두 가지의 조절 양상을 보였다. 그러나 subconfluent 세포의 경우에는 세포의 복제 빛 collagen 합성 모두에 TGF-$\beta$는 아무런 효과를 나타내지 못하였다. 본 연구결과는 TGF-$\beta$가 glomerulosclerosis에 있어서 중요한 역할을 하리라는 가능성을 제시해주고 있다. The effect of TGF-$\beta$ on cell replication and collagen synthesis in primarily cultured mesangial cells from rats was studied in vitro. The TGF-$\beta$ was purified from human platelets by acidic ethanol extraction and gel filtration with FPLC. The effect of TGF-$\beta$ on the DNA synthesis and the collagen synthesis in mesangial cells depended on both TGF-$\beta$ concentration and cell density in monolayer culture. Concentrations of TGF-$\beta$ ranging from 0.1~15 ng/ml were evaluated for their effects upon DNA synthesis. In confluent cells, when compared to the growth rate in standard medium, TGF-$\beta$ concentrations in the range 0.1~15 ng/ml reduced a cell proliferation up to 35%, suggesting inhibition of cell division. The effect of TGF-$\beta$ on collagen synthesis in mesangial cells was biphasic. In confluent cells, the addition of TGF-$\beta$ induced a 2-fold increase in the production of collagen when compared with cells grown in standard medium. The maximal effect of TGF-$\beta$ occurred at 0.5 ng/ml. At higher concentrations there was a decrease in the action of TGF-$\beta$ with the effects on collagen production. In subconfluent cells, however, TGF-$\beta$ showed no significant effects on the DNA synthesis and the collagen synthesis at all concentrations. These results support that TGF-$\beta$ may play an important role as a multifunctional regulator in the pathogenesis of glomerulosclerosis.

Diglycidyl ether of bisphenol A-Methylene dianiline-Succinonitrile계의 역학적 성질

조성우,심미자,김상욱,Cho, Sung-Woo,Shim, Mi-Ja,Kim, Sang-Wook 한국재료학회 1992 한국재료학회지 Vol.2 No.3

Succinonitrile을 첨가한 새로운 에폭시 수지, diglycidyl ether of bisphenol A(DGEBA)/4, 4'-methylene dianiline(MDA)/succinonitrile(SN)계의 역학적 성질을 충격 저항실험과 응력 변형실험을 통하여 곁화반응 특성과 반응기구를 근거로 하여 고찰하였다. DGEBA/MDA계에 각각 다른 succinonitrile의 함량을 포함하는 계를 $80^{\circ}C$에서 1.5시간 동안 경화시킨 후 완전히 경화를 이루기 위하여 $150^{\circ}C$에서 1시간 동안 경화시킨 후 시험한 결과 Succinonitrile의 함량이 증가함에 따라 본 계의 충격강도는 점차적으로 증가하였으나 인장강도는 감소하였다. 그리고 Young률은 거의 일정하게 나타났으며, 신도는 succinonitrile의 함량이 10phr에서 최대값을 보였다. 본 실험으고부터 얻은 결과는 succinonitrile이 첨가됨으로써 주 사슬간의 결합길이가 연장되었기 때문임을 알았고, 적당량의 succinonitrile을 첨가함으로 에폭시 수지의 유연성이 개선됨을 알 수 있었다. The new epoxy resin, diglycidyl ether of bisphenol A(DGEBA)/4, 4'-methylene dianiline (MDA)/succinonitrile system, containing the reactive additive succionitrile was investigated through the impact test and the stress-strain test on the basis of the behavior of cure reaction and the cure mechanism. The new epoxy resin system, having the different succinonitrile contents, were cured at $80^{\circ}C$for 1.5 hour and then in order to cure completely at $150^{\circ}C$ for 1 hour. It was shown that as the succinonitrile content increased, impact strength was gradually increased, tensile strength was decreased, almost constantly Young's modulus was sustained and elongation was increased until the succinonitrile content was increased to 10phr, and then decreased. From the experimental results, it can be concluded that the chemical bonding length between the main chains was extended by adding the reactive additive succinonitrile. It was also found that the flexibility of epoxy resin was improved by adding the succinonitrile.

PubMed를 통한 소아질환에 대한 추나 치료 연구의 최신 동향

조성우,Cho, Sung-Woo 대한한방소아과학회 2010 대한한방소아과학회지 Vol.24 No.2

Objectives We aimed reviewing studies related to the treatment of children by Chiropractic treatment. Methods We referred to PubMed by using searching keywords of chiropractic and the terms of pediatrics, such as child, children, juvenile, pediatric, infant. Twenty four papers were found. Results 1. We found twenty four papers about pediatric and chiropractic. 2. Chiropractic was used in various pediatric diseases and was shown to be effective. 3. There were several views on safety and effectiveness of pediatric chiropractic. Conclusions Applying of pediatric chiropractic was broad, and it was effectively cure for pediatric diseases.

EnergyPlus를 이용한 수평형의 지열 히트펌프와 어스튜브를 조합한 시스템의 성능 검토

조성우,Cho, Sung-Woo 한국지열에너지학회 2017 한국지열에너지학회논문집 Vol.13 No.2

This study is performed to performance of the combined system the GSHP (Ground Source Heat Pump) system with the Earth tube system using EnergyPlus program. The Earth tube system using fan is characteristics as supply lower (higher) air temperature than outdoor air temperature in cooling and heating seasons, the GSHP system is characteristics as small indoor air temperature variation range. As the results of Earth tube + GSHP system simulation, GSHP power can be reduced than the GSHP single operation as 17.3% in cooling seasons and 32.5% in heating seasons, the GSHP design capacity can be replaced more small size.