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황준서,김정훈,정호경,허장원,김성준,유영석.Joon Seo Hwang. M.D... Jeong Hun Kim. M.D... Ho Kyung Choung. M.D... Jang Won Heo. M.D... Seong-Joon Kim. M.D... Young Suk Yu. M.D.. 대한안과학회 2007 대한안과학회지 Vol.48 No.9
Purpose: To study the clinical characteristics and visual prognosis of Leber’s congenital amaurosis in Korea. Methods: Children who were diagnosed with Leber`s congenital amaurosis at Seoul Natioanl University Children`s Hospital between 1992 and 2004, were included in this study. The medical records pertaining to the clinical characteristics and visual outcomes of the patients were retrospectively reviewed. Results: The mean age of the patients at presentation and during the subsequent follow-up period was 15.5 and 62.7 months, respectively. The principal symptoms included lack of fixation (69.0%) and nystagmus (23.8%). At first observation, nystagmus was found in 40 patients, and the appearance of the fundi were variable, including `normal` (23.8%), pigmentary degeneration (54.8%), vascular attenuation (35.7%) and macular coloboma (19.0%). At the age of three to five years, 44.4% of patients had hyperopia greater than +5D. At the time of last follow-up, the visual acuities of the patients who were examined after the age of four were `hand motion` in 68.7%, ≥20/400 in 9.4%. No patient had visual acuity better than 20/200. Eight (25%) patients could read with glasses or low-vision aids. Conclusions: The visual prognosis of patients with Leber’s congenital amaurosis was poor in most cases, but a majority of our patients displayed a stable clinical course. Progression was rare, and one fourth of the patients were able to read with appropriate aides. In conclusion, regular follow-up care to assess visual function is necessary for optimal outcomes.
이종주,김정훈,정호경,허장원,김성준,유영석,Jong Joo Lee,Jeong Hun Kim,Ho-Kyung Choung,Jang Won Heo,Seong-Joon Kim,Young Suk Yu 대한안과학회 2007 대한안과학회지 Vol.48 No.7
Purpose: To evaluate long-term changes in visual acuity, fundus findings and complications in X-linked juvenile retinoschisis. Methods: A retrospective chart review was conducted on 48 patients diagnosed with X-linked juvenile retinoschisis and followed for a minimum of 12 months. Results: Forty-eight males (mean age 5.7 years) were followed for a mean of 6.3 years. The mean visual acuities were 0.14 at the initial and most recent examinations without significant change (p=0.67). Macular abnormalities were seen in all eyes. Macular lesions varied as follows: decreased foveal reflex (12.5%), typical foveal schisis (77.1%), atrophic change (5.2%), and macula-involving peripheral schisis (5.2%). When patients had different macular findings, the mean visual acuities were significantly different among groups (p≤0.005), except those between the atrophic change group and the macula-involving peripheral schisis group. Peripheral schisis was detected in 66% of patients. The fundus findings were stationary during the follow-up period except in complicated cases with vitreous hemorrhage (15.6%). Conclusions: X-linked juvenile retinoschisis causes bilateral visual acuity loss, affecting maculae. In uncomplicated cases, changes in visual acuity and fundus findings were not significant during the follow-up period.
망막모세포종에서 항암화학요법과 경동공온열치료의 병용치료
양희경,김정훈,정호경,김성준,유영석.Hee Kyung Yang. M.D.. Jeong Hun Kim. M.D... Ho Kyung Choung. M.D... Seong Joon Kim. M.D... Young Suk Yu. M.D.. 대한안과학회 2008 대한안과학회지 Vol.49 No.10
Purpose: To evaluate the results of transpupillary thermotherapy combined with chemotherapy for the treatment of retinoblastoma. Methods: Retinoblastoma patients treated with chemotherapy and transpupillary thermotherapy from November, 2004 to October, 2007 were retrospectively reviewed. Local tumor control was assessed in terms of regression or recurrence, at 1 month after chemotherapy and each session of thermotherapy, as well as the final follow-up period. Result: Fifty-nine tumors were treated in 15 eyes of 11 children. Age at diagnosis was 7.4±6.9 months. Mean tumor diameter at the time of diagnosis was 2.2±2.1 disc diameters (DD) and mean tumor diameter at the time of initial thermotherapy was 1.8±1.7DD. Mean number of thermotherapy sessions for each tumor was 1.3±0.5. Total tumor regression was obtained for 96.6% of tumors after a mean follow-up of 22.3±10.7 months. The initial tumor size before thermotherapy was significantly smaller in the group of tumors showing total regression after the first session of thermotherapy. The time required for total regression after initial thermotherapy was related to the initial tumor size before thermotherapy. Conclusions: Transpupillary thermotherapy combined with chemotherapy is an effective modality for treating retinoblastoma, and the initial tumor diameter before treatment is a strong predictive factor of successful treatment response. J Korean Ophthalmol Soc 2008;49(10):1619-1628
한국인 시신경염 환자의 임상 양상 및 고용량 스테로이드 치료 효과
차동민,김성준,김정훈,정호경,유영석,Dong Min Cha,Seong Joon Kim,Jeong Hun Kim,Ho Kyung Choung,Young Suk Yu 대한안과학회 2011 대한안과학회지 Vol.52 No.9
Purpose: To investigate the clinical manifestation and response to high-dose steroid therapy in Korean optic neuritis patients. Methods: We retrospectively reviewed the medical records of 13 patients diagnosed with optic neuritis who were treated with high-dose steroid and who were followed-up for more than three months in Seoul National University Hospital between January 2005 and December 2008. Results: Pain on extraocular movement (EOM) and disc swelling were observed in 61% (8/13) patients diagnosed with optic neuritis. Visual acuity (VA) improved to more than 20/40 in 77% (10/13) of patients after high-dose steroid therapy. The patients who resolved within one month recovered VA a mean of 18 days after onset. The recovery period had nothing to do with the initial time of high-dose steroid therapy. Conclusions: Pain on EOM was less frequently observed and disc swelling was more frequent in Korean patients than have been reported in Caucacian patients. The recovery period of optic neuritis was not influenced by the initial time of high-dose steroid therapy. J Korean Ophthalmol Soc 2011;52(9):1083-1088
초음속 터번 익렬 앞전 형상 및 노즐-익렬 간격에 따른 유동 특성에 대한 실험적 연구
조종재,김귀순,김진한,정은환,정호경,Cho Jong-Jae,Kim Kui-Soon,Kim Jin-Han,Jeong Eun-Hwan,Jeong Ho-Kyung 한국추진공학회 2005 한국추진공학회지 Vol.9 No.4
본 연구에서는 초음속 충동형 터빈의 유동특성을 알아보기 위해 소형 초음속 풍동을 설계하였으며 Single pass Schlieren system을 이용하여 유동을 가시화하였다. 실험은 2차원 초음속 노즐과 익렬을 조합하여 블레이드 앞전 형상과 노즐-익렬 간극에 따라 실시하였다. 실험을 통해 충격파를 포함한 복잡한 유동 형태와 노즐-익렬, 충격파-경계층 상호작용 등을 관찰할 수 있었다. In this paper, a small supersonic wind tunnel is designed and built to study the flow characteristics of a supersonic impulse turbine cascade. The flow is visualized by means of a single pass Schlieren system. The supersonic cascade with 2-dimensional supersonic nozzle was tested for various blade leading edge shapes and gaps between the nozzle and cascade. Highly complicated flow patterns including shocks, nozzle-cascade interaction and shock boundary layer interactions are observed.
한상범,김성준,김정훈,정호경-,유영석,Sang Beom Han,Seong Joon Kim,Jeong Hun Kim,Ho Kyung Choung-,Young Suk Yu 대한안과학회 2007 대한안과학회지 Vol.48 No.7
Purpose: To obtain useful information for counseling patients with Usher syndrome by analyzing the characteristics of its ophthalmologic manifestations. Method: The records of eight patients were reviewed for visual acuity, refractive error, Goldmann perimetry, electroretinogram, and other abnormalities. Results: The best corrected visual acuity was 20/30 or better, bilaterally in six patients. All patients showed retinal findings characteristic of of retinitis pigmentosa. All seven patients who received Goldmann perimetry showed visual field defect. Furthermore, electroretinograms taken from seven patients were all extinguished. Six patients had myopic astigmatism, with one showing high myopia. Two patients showed exotropia. No correlation was found between the severity of the ophthalmologic problems and the level of the hearing loss or vestibular dysfunction. Conclusions: Visual acuity was relatively preserved in most patients. Usher syndrome can be accompanied by strabismus, myopia, and even high myopia.