바나듐 - 비스무스계 촉매상에서 부탄 및 부텐의 선택산화반응 연구

정지훈,허성기,홍석인 ( Ji Hoon Jung,Sung Ki Huh,Suk In Hong ) 한국화학공학회 1995 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.33 No.3

The effect of reducing agents and bismuth as a additives used in preparing the VPO catalysts were investigated through selective oxidation of butane and butene to malefic anhydride. Bismuth added catalyst(VPBiO) increased the formation of malefic anhydride in butene oxidation, but it decreased the selectivity of malefic anhydride in butane oxidation. UV-DRS analysis showed that the charge transfer energy of VPBiO catalysts were higher than VPO catalysts, and it resulted in increasing the selectivity of malefic anhydride in butene oxidation. XRD study showed that the portion of R-VOPO₄ structure and the ratio of [020] face of (VO)₂P₂O_7 structure were increased with adding bismuth, and it was related to the selectivity of malefic anhydride. Also the mean valence of vanadium was increased with increasing the portion of β-VOPO₄ phase.

『동의보감사전』 편찬을 위한 표제어 추출에 관한 연구 - 코퍼스 분석방법을 바탕으로 -

정지훈,김도훈,김동율,Jung, Ji-Hun,Kim, Do-Hoon,Kim, Dong-Ryul 한국의사학회 2016 한국의사학회지 Vol.29 No.1

This article attempts to extract headwords for complication of "Donguibogam Dictionary" with Corpus-based Analysis. The computerized original text of Donguibogam is changed into a text file by a program 'EM Editor'. Chinese characters of high frequency of exposure among Chinese characters of Donguibogam are extracted by a Corpus-based analytical program 'AntConc'. Two-syllable, three-syllable, four-syllable, and five-syllable words including each Chinese characters of high frequency are extracted through n-cluster, one of functions of AntConc. Lastly, The output that is meaningful as a word is sorted. As a result, words that often appear in Donguibogam can be sorted in this article, and the names of books, medical herbs, disease symptoms, and prescriptions often appear especially. This way to extract headwords by this Corpus-based Analysis can suggest better headwords list for "Donguibogam Dictionary" in the future.

흰쥐의 염증반응에 대한 CW-501027과 CW-501029의 억제효과

정지훈,심재호,양성준,민영실,송현주,우재광,김용성,조영래,손의동,Jung, Ji-Hoon,Sim, Jae-Ho,Yang, Sung-Jun,Min, Young-Sil,Song, Hyun-Ju,Woo, Jae-Gwang,Kim, Yong-Sung,Cho, Young-Rae,Sohn, Uy-Dong 대한약학회 2004 약학회지 Vol.48 No.6

The use of nonsteroidal anti-inflammatory drugs (NSAIDs) is limited by their ability to induce gastrointestinal injury. It has been shown that nitric oxide (NO), similar to pro staglandins (PGs), appears to play an important role in gastric mucosal defence. We hypothesized that NSAIDs contained NO group would be less acutely toxic to the gastric mucosa, but would not interfere with their ability to suppress inflammatory process in rats. We have compared the ulcerogenic and anti-inflammatory effect of CW-501029 (NO-NSAIDs), CW-501027 (NSAIDs) and indomethacin. Both did not change mean blood pressure and heart rates, indicating that they had no side effect on cardiovascular system. We found that CW-501029 increased nitrite/nitrate levels without changing of blood pressure and heart rates. We suggest that it may help gastric mucosal blood flow, the which helps reducing the discomfort in astrointestinal system. Carrageenan-induced PGE2 increase was reduced in a similar tendency when compared CW-501027 or CW-501027 with control in back exudate of rats, but CW-501029 less reduced PGE2 than CW-502027 or indomethacin in gastric tissues. CW-501027 or CW-501029 reduced platelet aggregation. From these results we suggest that CW-501029 may improve the side effect by reduction of short-term gastric injury and less inhibition of PGs synthesis.

뇌졸중 환자의 양하지 교차밀기 근력 검사와 균형의 상관 관계 연구

정지훈,김중휘,Jung, Ji-Hoon,Kim, Joong-Hwi 대한물리치료학회 2013 대한물리치료학회지 Vol.25 No.4

Purpose: This study was to find a correlation between the bilateral reciprocal leg press test and a the balance in chronic stroke patients. Methods: Eighteen patients performed an isokinetic leg press test consisting of a bilateral reciprocal and unilateral mode. Following the isokinetic leg press testing, subjects performed the balance test: Berg Balance Scale (BBS), Timed Up & Go (TUG) test, and stability limit. Pearson product moment correlation coefficients were used to determine the correlation between the mean score of the isokinetic leg press test, balance test in both affected and non-affected side. Results: This study indicated a significant correlation between the bilateral reciprocal leg press test and stability limit. There were significant correlation between non-affected side bilateral leg press(NBL) and BBS (r=0.501), affected side bilateral leg press (ABL) and non-affected side stability limit(NS) (r=0.614), ABL and total stability limit (TS) (r=0.493), NBL and affected side stability limit(AS) (r=0.480), NBL and NS (r=0.560), NBL and TS (r=0.563), among the patients. Conclusion: Measurement of the lower extremity strength using the bilateral reciprocal leg press test can be used as an evaluating tool of the balance test.

마약성 진통제 사용과 Cortisol 및 DHEAS와의 관계

정지훈,최윤선,김선미,이준영,김은혜,김정은,김이연,박희진,윤동진,Jung, Ji Hoon,Choi, Youn Seon,Kim, Seon Mee,Lee, June Young,Kim, Eun Hye,Kim, Jung Eun,Kim, E Yeon,Park, Hee Jin,Yoon, Dong Jin 한국호스피스완화의료학회 2015 한국호스피스.완화의료학회지 Vol.18 No.2

목 적: 치료 불가능한 암환자에서는 암으로 인한 전신적 쇠약 이외에 피로와 에너지 상실, 무력감, 식욕부진 및 통증 등이 공통적으로 나타나는 주요 증상으로 알려져 있으며 이러한 증상은 부신 기능 부전이 있을 때 나타나는 증상과 유사한 점이 많다. 또한 말기암환자의 통증은 중등도 이상이기 때문에 대부분 마약성 진통제로 조절하고 있는 경우가 많다. 본 연구에서는 마약성 진통제와 부신 기능 부전에 대한 관계를 알아보고자 한다. 방법: 2013년 11월부터 2014년 6월까지 7개월 동안, 만 18세 이상의 말기암환자 55명을 대상으로 혈장 cortisol, DHEAS 등을 측정하였다. 또한 환자의 마약성 진통제의 사용 기간 및 용량도 함께 조사하였고 마약성 진통제의 사용 기간 및 용량과 부신 기능을 대표할 수 있는 혈장 cortisol, DHEAS의 농도를 각각 비교하였다. 결과: Cortisol의 평균값은 $20.24{\mu}g/dL$, DHEAS의 평균값은 $44.41{\mu}g/dL$였으며, 상관 분석 결과 DHEAS와 마약성 진통제의 사용 기간 및 용량과의 관계는 통계적으로 유의한 수준의 관련성이 없었고, Cortisol의 경우 마약성 진통제의 사용 기간과는 유의한 관련성이 없었으나, 진통제의 사용 용량이 많을수록 Cortisol의 수치가 유의하게(P-value 0.0322) 상승되었다. 결론: 마약성 진통제의 사용 기간 및 용량에 따른 부신 기능의 저하는 통계적으로 유의한 연관성을 보이지 않았으나 진통제를 사용하고 있는 말기암환자들의 부신 기능을 대표할 수 있는 지표인 DHEAS 값은 대부분 정상 이하로 낮아져 있는 모습을 보였다. Purpose: Fatigue, energy loss, feeling of helplessness, poor appetite, pain besides general weakness are major symptoms presented to terminally ill cancer patients. These symptoms are similar to those that appeared with adrenal insufficiency. Also, for terminally ill cancer patients who are hospitalized for palliative care, opioid agents are prescribed to control moderate to severe pain. We studied the relationship of opioid agents and adrenal insufficiency. Methods: From November 2013 through June 2014, we monitored the serum level of cortisol and dehydroepiandrosterone sulfate (DHEAS, serum) in 55 cancer patients who were over 18 years old and were treated at a hospice center. We also checked the treatment period and dosage of opioid agents. Results: The DHEAS level, treatment period and dosage of opioid agents did not have significant correlation. Correlation between the serum cortisol level and the opioid agent treatment period was not significant either, but the serum cortisol level was positively correlated with the dosage of opioid agents (P value 0.0322). Conclusion: This study did not identify a novel link between treatment period, dosage of opioid agents and adrenal insufficiency. But, the DHEAS level was mostly below the normal level in patients who were treated with opioid agents.

마약성 진통제 사용과 부신기능부전

정지훈,최윤선,김정은,김이연,Jung, Ji Hoon,Choi, Youn Seon,Kim, Jung Eun,Kim, E Yeon 한국호스피스완화의료학회 2014 한국호스피스.완화의료학회지 Vol.17 No.3

치료 불가능한 암환자들은 전신적 쇠약 이외에 피로와 에너지 상실, 무력감, 식욕부진 및 통증 등이 주요 증상으로 알려져 있으며, 이러한 증상들은 부신기능부전으로 인한 증상들과 매우 유사한 양상을 보인다. 부신기능부전으로 인한 증상들은 가벼운 증상부터 생명을 위협하는 증상까지 다양하게 나타날 수 있으며, 이러한 부신기능부전은 다양한 원인에 의해 나타난다. 완화의료병동에 입원 중인 말기암환자들 중 중등도 이상의 통증을 호소하는 환자들은 마약성 진통제를 사용하여 통증 조절을 받고 있는데, 이러한 마약성 진통제의 사용은 부신기능에 영향을 주는 것으로 알려져 있다. 동물 및 비암성 통증을 호소하는 환자 대상으로 여러 연구들이 시행되었으며 대부분의 연구에서 마약성 진통제로 인해 부신기능의 저하가 나타났음을 보여주었다. 그러나 아직 암환자를 대상으로 한 마약성 진통제로 인한 부신기능의 저하에 대한 연구 결과는 드물다. 마약성 진통제로 통증 조절을 받고 있는 완화의료병동에 입원한 말기암환자들의 부신기능을 측정함으로써 마약성 진통제의 종류, 사용기간 및 용량과 부신기능의 관계를 파악하고 이에 따른 대증치료 및 호르몬 보충 요법은 환자들의 예후 및 삶의 질 향상에 도움을 줄 수 있을 것으로 기대된다. The major symptoms of terminally ill cancer patients are fatigue, loss of energy, feeling of helplessness, poor appetite and pain as well as general weakness, which are very similar to symptoms of adrenal insufficiency. Adrenal insufficiency-induced symptoms widely vary from mild symptoms to life-threatening conditions and may be resulted from variable medical causes. For terminally ill cancer patients who are hospitalized for palliative care, opioid agents are prescribed to control moderate to severe pain. The use of acute or chronic opioid agents is believed to negatively affect adrenal gland function. In most studies of opioid effects (preclinical/clinical with animal subjects or and patients suffering non-malignant pain, adrenal insufficiency and hormonal abnormalities were observed as side effects. However, opioid-induced adrenal insufficiency has been rarely reported in studies with patients with malignant cancer pain. Relationship between the type, treatment period, dosage of opioid agents and hormonal abnormalities can be examined by measuring the functional level of the adrenal glands. We hope to improve patient's quality of life by indicating hormone substitution to treat symptoms of adrenal insufficiency.

TPD 및 TPR 에 의한 바나듐 - 몰리브덴 - 인 혼합산화물 촉매의 반응특성에 관한 연구

정지훈,천진우,홍석인 ( Ji Hoon Jung,Jin Woo Chun,Suk In Hong ) 한국화학공학회 1991 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.29 No.2

Oxidation reactions of methylcyclopentane(MCP) and cyclopentadiene(CPD) on the V-Mo-P mixed oxide catalyst were investigated with the composition of Mo and P. The conversion of MCP and CPD and the selectivity of MA were also examined at various reaction temperatures. Studies of activation points on the catalyst surfaces were performed through the temperature programmed desorption. In the oxidation of CPD, the highest value of MA selectivity was observed by using the V-Mo-P mixed catalyst(V : Mo : P=1 : 1.34 : 0.11). The conversion of MCP and CPD resulted in decreasing with increasing composition ratio of molybdenum and phosphorous in the V-Mo-P mixed oxide catalyst. The selectivity of MA in the oxidation of CPD resulted in increasing with increasing composition ratio of molybdenum and phosphorous in the catalyst. However, the selectivity of MA in the oxidation of MCP was decreased with increasing molybdenum and phosphorous composition ratio. In the temperature programmed reaction(TPR) spectrum, four desorption peaks were observed and the number of the observed peaks were same as the number of reaction products. It was founded the main product of those oxidation reactions, MA and PA, were produced at different activation point of the catalyst.

보안저장장치 취약성 분석

정지훈(Ji-Hoon Jung),김석현(Suk-Hyun Kim),김민수(Min-Su Kim),노봉남(Bong-Nam Noh) 한국정보과학회 2009 한국정보과학회 학술발표논문집 Vol.36 No.2D

국가 또는 회사의 기밀정보나 개인의 정보를 보호하기 위하여 보안저장장치가 많이 사용되고 있다 . 보안저장장치의 역할은 신뢰된 사용자만이 데이터에 접근할 수 있고, 만약 분실 되었을 경우 제 3자가 데이터에 접근하는 것을 원천 봉쇄하는 것이다. 하지만 시중에 유통되고 있는 보안저장징치 제품 중 일부에는 데이터가 유출될 수 있는 취약점이 존재한다. 이러한 취약점은 제품의 신뢰성에 치명적인 영향을 주며 제3자가 제품을 통해서 보호되어야 할 정보를 빼낼 수 있다. 본 논문에서는 시중에 유통중인 몇 가지 제품의 취약성을 조사 분석 하였다. 그 결과 접근통제 우회, 암호화된 데이터의 복호화와 같은 취약점을 발견하였다.

배터리 임피던스 추정기반 멀티스텝 알고리즘 적용 급속 충전 시스템 설계

정지훈(Ji-hoon Jung),김봉철(Bong-chul Kim),방성록(Sung-rok Bang),김기영(Ki-young Kim) 대한전기학회 2015 정보 및 제어 심포지엄 논문집 Vol.2015 No.10

요양보호사의 노인에 대한 태도가 서비스 질에 미치는 영향

정지훈(Ji hoon Jung) 사회복지정책실천회 2016 사회복지정책과 실천 Vol.2 No.2

본 연구의 목적은 노인요양시설에서 돌봄서비스를 제공하는 요양보호사가 가지는 노인에 대한 태도가 서비스 질에 미치는 영향을 공감능력이 조절하는지 검증하기 위한 것이다. 연구를 위하여 부산광역시에 소재한 노인요양시설 15개소의 요양보호사 181명을 대상으로 자료를 수집하였다. 자료 분석방법으로는 기술통계, 상관관계분석, 다중회귀분석이 사용되었다. 연구결과를 요약하면, 요양보호사의 노인에 대한 태도가 서비스 질에 미치는 영향이 공감능력에 따라 달라지는 것으로 나타났다. 구체적으로 노인에 대한 태도(β=31, p<.001)와 공감능력(β=.49, p<.001)이 높을수록 서비스 질이 높은 것으로 분석되었다. 또한, 공감능력이 떨어질수록 노인에 대한 태도가 서비스 질에 더 영향을 미치는 것으로 나타나(β=-.13, p<.05) 공감능력의 조절효과를 확인할 수 있었다. The purpose of this study is to see whether attitudes towards the elderly with caregivers to provide care services in long-term care facilities give what effect the quality of service, and attitude and quality of services for the elderly In the relationship, it is to verify whether represents empathy capacity effect of this adjustment in caregivers. For this reason, it is conducted a questionnaire survey of caregivers 181 people of long-term care facilities 15 facilities in Busan, in the data analysis methods, descriptive statistics, correlation analysis, multiple regression analysis was used. To summarize the results of the study, attitude to geriatric care protection mechanic influence on the quality of service has been found to be dependent on the sympathetic capabilities. Specifically, the attitude towards the elderly (β = 31, p <.001) and empathy capability (β = .49, p <.001) higher, it has been analyzed that there is a high quality of service. In addition, the more empathy ability is reduced, attitudes toward the elderly are shown to affect the quality of service (β = -.13, p<.05) confirmed the moderating effects of empathy ability. In this study, in the existing policy approach for enhancing the quality of caregivers protection services, it is significant in that it was examined for empathy ability as a more specific method. Also, it is possible to check the moderating effect of empathy capacity in relation to the quality of the attitude and services for geriatric caregivers, it can be enhanced empathy capacity in a realistic method that can improve the quality of service It provided the theoretical support for the service provided. Future studies, it is necessary to try to study the relationship between empathy capacity and quality of service including caregivers in long-term care facilities and other various areas, it is possible to influence the quality of service there is a need to study for various personal and environmental factors.