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건강기능식품의 기능성을 중심으로 한 오메가-3 지방산 함유유지의혈행개선 효과에 대한 체계적 고찰
정세원,김지연,백주은,김주희,곽진숙,권오란,Jeong, Sewon,Kim, Ji Yeon,Paek, Ju Eun,Kim, Joohee,Kwak, Jin Sook,Kwon, Oran 한국영양학회 2013 Journal of Nutrition and Health Vol.46 No.3
Omega-3 polyunsaturated fatty acids are essential fatty acids because humans cannot synthesize them de novo and must obtain them in their diet. Fish and fish oil are rich sources of omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Significant evidence of the beneficial role of dietary intake of omega-3 fatty acids in blood flow has been reported and putative mechanisms for improvement of blood flow include anti-thrombotic effects, lowered blood pressure, improved endothelial function, and anti-atherogenic effects. Edible oils containing omega-3 fatty acids were registered as functional ingredients in the Korea Health Functional Food Code. Although omega-3 fatty acids have been evaluated by the Korea Food and Drug Administration (KFDA) based on scientific evidence, periodic re-evaluation may be needed because emerging data related to omega-3 fatty acids have accumulated. Therefore, in this study, we re-evaluated scientific evidence for the effect of omega-3 fatty acids as a functional ingredient in health functional food on improvement of blood flow. A comprehensive literature search was conducted for collection of relevant human studies using the Medline and Cochrane, KISS, and IBIDS databases for the years 1955-2012. Search keywords were used by combination of terms related to omega-3 fatty acids and blood flow. The search was limited to human studies published in Korean, English, and Japanese. Using the KFDA's evidence based evaluation system for scientific evaluation of health claims, 112 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting a relation between omega-3 fatty acids and blood flow. Among 112 studies, significant effects on improvement of blood flow were reported in 84 studies and the daily intake amount was ranged from 0.1 to 15 g. According to this methodology of systematic review, we concluded that there was possible evidence to support a relation between omega-3 fatty acid intake and blood flow. However, because inconsistent results have recently been reported, future studies should be monitored.
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정세한(Sae-han, Jeong),권재현(Jay Hyoun, Kwon),김정욱(Junguk, Kim) 한국측량학회 2019 한국측량학회 학술대회자료집 Vol.2019 No.4
서남해안은 해안선이 복잡한 리아스식 해안의 특성을 갖고 있으며, 간사지가 넓게 발달되어 있다. 수심은 선박의 항행 안전을 위한 중요한 요소이다. 간사지의 수심을 측량하는 여러 방법 중 항공사진을 이용하는 방법은 소규모 지역에는 경제성이 떨어지고, 위성영상을 이용하는 방법은 최신성이 떨어지고, 에코사운드를 이용하는 방법은 선박이 접근하기 어려워 정밀한 측량이 어렵다. 본 연구는 무인항공기를 이용한 간사지 수심측량의 적용성을 확인하기 위해 기존 수심 측량방법으로 어려웠던 간사지 및 저수심 지역을 무인항공기를 이용하여 측량하고, 싱글빔을 사용한 기존 성과와 비교하여 정확도를 검증하였다. 본 연구에선는 간사지가 넓게 발달한 전라남도 해남군 서흥리 일원에 고정익 무인항공기에 2,400만 화소의 카메라를 탑재하여 110~150m에서 중복율 60~80%를 주었고, GCP 간격은 500m, 검사점은 한 도엽에 3점을 설치하였고, 지상기준점의 위치는 Network-RTK를 사용하여 결정하였다. 촬영된 사진은 각 장마다 촬영정보를 입력하여 자동영상 정합하였고, GCP와 검사점을 매칭하여 1m×1m 간격의 DSM을 생성하여 정사영상을 제작하였다. 정합된 정사영상의 지상기준점 RMSE는 X=0.0105m, Y=0.0091m, Z=0.0103m 임을 확인할 수 있었다. 연구대상지의 중첩부를 무인항공기를 이용한 수심성과와 싱글 빔을 이용한 수심성과를 비교한 결과 평균 0 ~ 0.1m의 수심오차를 확인 할 수 있었고, 이는 수로측량 특 등급 수심별 허용오차 기준을 만족 하는 것이다. 이를 통해 무인항공기를 이용해 접근이 어려운 간사지 구간에 수심측량한 성과의 적용성 여부를 확인할 수 있었다. 또한 무인항공기를 이용한 정사영상과 수심에 조석값을 보정함으로써 해안선을 작도할 수 있었으며, 이를 기존 해안선과 비교하여 해안선의 변화여부도 확인할 수 있었다.
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정세연,황재웅,김석민,정재한,최창민,정우상,문상관,조기호,김영석,선종주,Chung, Sae-Yun,Hwang, Jae-Woong,Kim, Seok-Min,Jung, Jae-Han,Choi, Chang-Min,Jung, Woo-Sang,Moon, Sang-Kwan,Cho, Ki-Ho,Kim, Young-Suk,Sun, Jong-Joo 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.2
Objectives : In this study we investigated BDI(Beck Depression Inventory) improvement of poststroke depression Patients who took the acupuncture with aromatherapy, in order to examine its capacity as a new treatment and to establish a primary data for further studies of developments of diverse Practical acupunctures. Methods : Physicians applied the acupuncture with aromatherapy every day for two weeks. We had evaluated baseline characteristics and BDI of all Patients, and revaluated BDI and examined the side effects two weeks later. The qualified Patients were classified into two groups, depression group (more than 10 points and 10 in BDI) and non-depression group (less than 10 points in BDI) according to the baseline BDI. Results : The study was completed with 27stroke patients. The acupuncture with aroma therapy was applied in 18 post-stroke depression patients and 9 non-depression patients for 2 weeks. And the result showed that the BDI scores in the depression group decreased to $16.5{\pm}11.1$ after the treatment (compared to $24.4{\pm}11.5$ before the treatment). so proved the significant effect on post-stroke depression of the acupuncture. On the other hand. the scores in the non-depression group increased to $9.2{\pm}9.5$ (compared to $3.3{\pm}3.0$). Conclusions : The acupuncture with aromatherapy applied on post-stroke depression patients showed the effect of BDI improvement. Further researches are needed to evaluate the distinct functional mechanism of acupuncture with aromatherapy, and to estimate its effectiveness by well-designed randomized controlled trial.
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간동맥 화학색전술 후 간암 환자의 통증관리와 통증 영향요인
정세나(Jung, Se Na),선제인(Seon, Je In),김광성(Kim, Kwang Sung) 대한종양간호학회 2017 Asian Oncology Nursing Vol.17 No.2
Purpose: The purpose of this study was to identify the factors of pain and pain management after transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC). Methods: Participants were 99 inpatients with HCC who underwent TACE at C University in Seoul from May to October 2016. The instruments used in this study were the Numerical Rating Scale (NRS), the Pain Management Index (PMI), and the modified Patient Outcome Questionnaire (American Pain Society). The data were analyzed using SPSS 24.0, specifically descriptive statistics, t-test, ANOVA, and multiple regression. Results: The percentage of patients who experienced pain after TACE was 66.7%. The mean pain score immediately after TACE was 4.43±2.36 and the highest score on average was 6.58±2.32. The pain score was highest at 5.24±5.67 hours after TACE. Significant factors influencing pain after TACE were the extent of embolization and the ECOG (Eastern Cooperative Oncology Group) score, which explained 26% of the variance in pain. PMI scores revealed that 33.3% of the participants were inadequately treated for pain. Conclusion: In order to properly manage pain after TACE, medical staff need accurate understanding of pain and to administer the appropriate dosage of analgesics. The development of pain management protocol for patients who have undergone TACE would help achieve these goals.
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