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김지현,정부윤,이용주,최환석 대한가정의학회 2019 Korean Journal of Family Practice Vol.9 No.1
Background: Bioelectrical impedance analysis (BIA) can be used to estimate body composition. To achieve the best results, the manufacturer’s guidelines advise that individuals should restrict intake of food or caffeine, avoid vigorous exercise for 4 hours, and drink 2–4 glasses of water 2 hours before testing. We evaluated the appropriacy of drinking 2–4 glasses of water 2 hours before the BIA, as the validity of this indication has not been specifically demonstrated, by comparing intracellular water (ICW), extracellular water (ECW), total body water (TBW) in the fasting state, and after 1 and 2 hours of ingesting 500 mL of water. Methods: Twenty-nine healthy adult men (n=10) and women (n=19) were recruited for the study. In the fasting state, the InBody 720 analyzer was used as multi-frequency (MF)-BIA and the output was recorded to determine the exact weight. Subsequently, Medinex BIA 450 analyzer was used as single-frequency (SF)-BIA, and the output was recorded. After drinking 500 mL of water 1 or 2 hours before assessment, the BIA tests were repeated as indicated above, and the ICW, ECW, TBW were compared by repeated measures ANOVA. Results: SF-BIA measurements showed that compared to fasting state, the ICW decreased by approximately 0.56 L after 1 hour of drinking (P=0.001). The ECW was increased by about 0.62 L, 1 hour after drinking water compared to the fasting state (P=0.002). There were no significant differences between the results of BIA testing at 1 and 2 hours of fluid intake. The MF-BIA measurements indicated that testing after fasting, or 1 or 2 hours after fluid intake, did not result in significantly different ICW and ECW values. TBW showed no significant differences in the fasting state, or after 1 or 2 hours of fluid intake for both SF and MF. Conclusion: Several studies have shown that bioelectrical impedance should be measured in the fasting state. But not the food intake, drinking 500 mL of water may be permitted when measuring MF-BIA. However, for SF-BIA measurements, fluid intake resulted in an increase in the ECW level and a decrease in ICW. 연구배경: Bioelectrical impedance analysis (BIA)는 체성분 분석방법으로 단주파수 방식과 다주파수 방식이 있다. 공통적으로 BIA는 측정 전 최상의 결과를 얻기 위하여 테스트 받기 전 24시간 내 알코올섭취금지, 4시간이내운동, 카페인, 음식섭취 금지, 2시간전에 2–4컵의 물 섭취할 것과 같은 지침 사항을 준수할 것을 권고한다. 본 연구에서는 지침 사항 중 2시간 전 2–4컵의 물 섭취에 대해 공복 상태, 수분섭취 1시간 후, 2시간 후의 extracellular water (ECW), intracellularwater (ICW), total body water (TBW) 수치를 비교하여 그 적절성에 대해 평가하고자 한다. 방법: 성인남녀 29명(남 10명, 여 19명)을 대상으로 간단히 성별, 나이, 체중, 신장, 병력, 월경기간 유무, 카페인, 알코올 섭취 유무, 운동,최소 4시간 동안 공복 상태인지 확인한 뒤, 동의서를 받고 공복 4시간 상태(9:30 AM)에 InBody 720 (multi-frequency [MF]-BIA)을 먼저측정하여 정확한 체중값을 얻은 뒤 이어서 Medinex BIA 450 (singlefrequency [SF]-BIA)을 측정하여 출력값을 얻었다. 물 500 mL를 섭취하고 1시간 후(10:30 AM), 2시간 후(11:30 AM) 같은 과정을 반복하였고 얻어진 출력값 중 ICW, ECW, TBW를 repeated measures ANOVA로 비교 분석하였다. 결과: ICW 같은 경우 SF의 경우 공복 상태에 비해 1시간 후에 0.56 L감소한 것으로 나타났고(P=0.001), 1시간 후와 2시간 후의 유의한 차이는 없었다. MF는 공복 상태, 1시간 후, 2시간 후의 ICW에 유의한차이는 없었다. ECW는 SF의 경우 공복 상태에 비해 1시간 후에 0.62L 증가한 것으로 나타났고(P=0.002), 1시간 후와 2시간 후의 유의한차이는 없었다. MF는 공복 상태, 1시간 후, 2시간 후의 ECW는 유의한 차이는 없었다. TBW는 SF, MF 모두 공복 상태, 1시간 후, 2시간 후에 유의한 차이가 없었다결론: 여러 연구에서 BI는 공복에 측정되어야만 한다고 증명하였다. 하지만, 음식의 섭취가 아닌 물은 500 mL 정도는 MF-BIA 측정 시 마셔도 무방한 것으로 판단되고, SF-BIA는 수분섭취에 ICW, ECW 수치에 있어서 좀더 민감한 반응을 보이는 것으로 드러났다
토양 공극수 내 Cu의 존재형태가 terrestrial biotic ligand model을 이용한 보리의 급성독성 예측에 미치는 영향
안진성,정부윤,이병준,남경필,An, Jinsung,Jeong, Buyun,Lee, Byungjun,Nam, Kyoungphile 한국지하수토양환경학회 2017 지하수토양환경 Vol.22 No.5
In this study, the predictive toxicity of barley Hordeum vulgare was estimated using a modified terrestrial biotic ligand model (TBLM) to account for the toxic effects of $CuOH^+$ and $CuCO_3(aq)$ generated at pH 7 or higher, and this was compared to that from the original TBLM. At pH values higher than 7, the difference in $EA_{50}\{Cu^{2+}\}$ (half maximal effective activity of $Cu^{2+}$) between the two models increased with increasing pH. As Mg concentration increased from 8.24 to 148 mg/L in the pH range of 5.5 to 8.5, the difference in $EA_{50}\{Cu^{2+}\}$ increased, and it reached its maximum at pH 8. The difference in $EC_{50}[Cu]_T$ (half maximal effective concentration of Cu) between the two models increased as dissolved organic carbon (DOC) concentration increased when pH was above 7. Thus, for soils with alkaline pH, the toxic effect of $CuOH^+$ and $CuCO_3(aq)$ are greater at higher salt and DOC concentrations. The acceptable Cu concentration in soil porewater can be estimated by the modified TBLM through deterministic method at pH levels higher than 7, while combination of TBLM and species sensitivity distribution through the probabilistic method could be utilized at pH levels lower than 7.
유류오염부지 시범적용을 통한 실외공기 오염물질흡입 노출경로에 대한 부지특이적 노출량 산정 방안에 대한 고찰
김상현,정현용,정부윤,노회정,김현구,남경필 한국지하수토양환경학회 2020 지하수토양환경 Vol.25 No.3
Exposure assessment methodology for outdoor air inhalation pathways (i.e., inhalation of volatile compounds and fugitivedust in outdoor air) was investigated. Default values of several parameters currently used in Korea (e.g., Q/C; inversevalue of concentration per unit flux, and frs; soil fraction in PM10) may not be suitable and lack site-specificity, as theyhave been adopted from the risk assessment guidance of the United States or the Netherlands. Such limitation can beaddressed to a certain degree by incorporating the volatilization factor (VF) and the particulate emission factor (PEF) withBox model. This approach was applied to an exposure assessment of a site contaminated with petroleum hydrocarbons inKorea. The result indicated that the suggested methodology led to more accurate site-specific exposure assessment foroutdoor inhalation pathways. Further work to establish methodology to determine site-specific Q/C values in Korea needsto be done to secure the reliability of the exposure assessment for outdoor air inhalation pathways.
오범조,이영구,정부윤,이경태,하철원 대한스포츠의학회 2019 대한스포츠의학회지 Vol.37 No.1
As interest in sports rapidly grows in Korea, fostering of elite athletes and preservation of the athletic ability no longer became the task of advanced countries only. In that aspect, health of athletes and their associated coaches, athlete trainers, team members such as team doctors, and even their families is certainly a matter of concern. Especially when it comes to the inoculation of infectious disease prevention, it needs to be considered as one of the most economical and effective ways to promote health in sports people as well as elite athletes. The purpose of this article is to go over the specific circumstances of the athletes and related literatures on vaccination. In addition, we provide recommendations on the vaccination of athletes regarding the actual situation of sports in Korea.