소아에서의 광절열두조충 감염 1례

이진수,김백남,손영모,이종원,임경일,Lee, Jin Soo,Kim, Baek Nam,Sohn, Young Mo,Lee, Jong Won,Im, Kyung-Il 대한소아감염학회 2001 Pediatric Infection and Vaccine Vol.8 No.1

기생충 감염이 거의 없는 최근, 저자들은 5세 여아에서 소아에서는 드문 광절열두조충 감염을 경험하였기에 문헌 고찰과 함께 보고하는 바이며, 생선회의 소비가 급증하고 쉽게 사먹을 수 있는 시장의 형성으로 환자의 증가가 예상되어 전국민적인 보건교육과 함께 비특이적 소화기 증상을 가진 환아에 대한 소아과 의사들의 자세한 문진과 의심이 요구된다고 본다. We experienced one rare case of Diphyllobothrium latum infection in childhood. It was proved by collection of worm after praziquantel treatment. Human diphyllobothriasis is chiefly caused through eating raw or unproperly cooked fish such as trout or salmon. This case was a 5-year old girl residing in Seoul, from whom a kind of pseudophyllidean tapeworm was detected in the feces. She would often eat sushi(raw fish) and had abdominal pain, but not revealed any sign of anemia. Obtained chain of worm segments that sized $0.25{\times}1.25cm$ was compatible with D. latum. Including the present 31 cases, total number of human D. latum infections proven by worms in Korea becomes 32 cases, and total number of child D. latum infections proven by worms in Korea becomes 4 cases.

Polyhydroxyamide/MWNT 나노복합체의 제조와 특성분석

이진수,지민호,이민호,백두현,Lee, Jin-Soo,Jee, Min-Ho,Lee, Min-Ho,Baik, Doo-Hyun 한국섬유공학회 2010 한국섬유공학회지 Vol.47 No.1

Polyhydroxyamide(PHA), a precursor polymer of polybenzoxazole(PBO), was synthesized by low temperature polymerization of 3,3'-dihydroxybenzidine(DHB) and isophthaloyl chloride(IPC) in N,N-dimethylacetamide (DMAc) medium. MWNT dispersions were prepared by ultrasonication of pristine MWNT(p-MWNT) and acid-modified MWNT(a-MWNT) in DMAc. PHA/a-MWNT and PHA/p-MWNT nanocomposite films were prepared by casting of mixed solution. The tensile properties of PHA/a-MWNT nanocomposite films were enhanced compared with those of pure PHA. DSC and TGA analyses revealed that the PHA/a-MWNT nanocomposites cyclized at lower temperature and showed better thermal stability compared to the pure PHA film.

항암화학요법과의 순차적, 그리고 병행적 요법으로서의 aRVS 투여로 장기 생존과 좋은 삶의 질을 유지한 전이성 비소세포폐암 증례보고

이진수,박형준,채진,김경석,정현식,이상헌,최원철,전성하,Lee, Jin-Soo,Park, Hyeong-Jun,Chae, Jean,Kim, Kyung-Suk,Jung, Hyun-Sik,Lee, Sang-Hun,Choi, Won-Choel,Cheon, Seong-Ha 대한한방내과학회 2011 大韓韓方內科學會誌 Vol.32 No.1

This report documents a case in which the administration of an herbal product, an extract of the lacquer tree, Rhus verniciflua Stokes, as sequential and concurrent treatment with chemotherapy was associated with a long term survival and good quality of life in a patient with metastatic non-small cell lung cancer(NSCLC). A 51-year-old Korean female was referred to the $M{\cdot}{\mu}$ Integrative Cancer Center, East-West Neo Medical centrer, Kyung Hee University for stage IV, metastatic NSCLC. She was treated with aRVS alone for 19 months and then received 1st line paclitaxel/carboplatin combined with aRVS, 2nd line gefitinib, and 3rd line pemetrexed. The number of cycles of pemetrexed administered was seventeen. aRVS was restarted as the 13th pemetrexed was administered. Pemetrexed with aRVS is currently ongoing. This patient has been alive for 41 months, and has been keeping a good performance status so far. We suggest aRVS as sequential and concurrent treatment with chemotherapy is an effective alternative treatment strategy.

고양이의 간기능 평가

이진수,Lee, Jin-Su 대한수의사회 2009 대한수의사회지 Vol.45 No.3

갑상선 딜레마

이진수,Lee, Jin-Su 대한수의사회 2008 대한수의사회지 Vol.44 No.5

보은지역 흑색셰일 분포지역에서의 암석-토양-식물계내 잠재적 독성원소들의 분산과 이동

이진수,전효택,김경웅,Lee, Jin-Soo,Chon, Hyo-Taek,Kim, Kyoung-Woong 대한자원환경지질학회 1997 자원환경지질 Vol.30 No.6

This study had three purposes: (1) to investigate the enrichment levels and dispersion patterns of potentially toxic elements in the rock-soil-plant system; (2) to evaluate the uptake ratios of heavy metals from soils into plants and (3) to assess the chemical speciation of heavy metals in soils. Rock, surface soil and plant samples were collected in the Boeun area underlain by black shales of the Okchon Zone. These samples were analyzed for multi-elements using INAA, ICP-AES and AAS. The maximum abundance of U in black shales is 16 mg/kg and radioactivity counts up to 300 cpm. In particular, Mo, V, Ba, Cd, Pb and U are enriched in black shales. Most of soils derived from black shales show high concentrations of U, As, Mo, Ba, Cu, Cd, Pb, Zn and mean concentrations of As and Mo in soils (20 mg/kg of As and 6.6 mg/kg of Mo) are higher than the permissible level suggested by Kloke (1979). Enrichment index values of soils are calculated and higher than 1.0 in the black shale area with the highest value of 6.4. Mean concentration of Cd in plants is higher than those of Cu, Pb and Zn. The concentration of Cd in plant species decreases in the order of Chinese cabbage > red pepper > soybean=sesame > rice stalk > com > rice grain. The biological absorption coefficients (BAC) in plants are in the order of Cd > Zn=Cu > Pb, which suggests that Cd is more bioavailable to plants than Cu, Pb and Zn. From the results of sequential extraction analysis of soils, relatively high proportion of Cu, Pb and Zn are present as residual fractions whereas that of Cd as non-residual fractions. Cadmuim occurs predominantly as exchangeable/water-acid soluble phase in soils, and Cd is more mobile and bioavailable than Cu, Pb and Zn.

초음파 유속측정 기술을 적용한 휴대용 초음파 유속계

이진수,Lee, Jin-Su 한국수자원학회 2016 물과 미래(한국수자원학회지) Vol.49 No.12

오염된 토양, 지하수 및 쌀의 인체노출에 따른 비소의 위해성 평가

이진수,전효택,Lee Jin-Soo,Chon Hyo-Taek 대한자원환경지질학회 2005 자원환경지질 Vol.38 No.5

본 연구에서는 폐금속광산 지역에서의 비소가 인체에 미치는 위해영향을 정량적으로 평가하기 위하여 동일, 옥동, 동정, 도곡 및 화천광산 주변 지역에서 광미, 토양, 농작물 및 지하수를 채취하여 화학분석을 실시하였다. 이들 폐금속광산 주변에 폐기된 광미내 비소 함량은 매우 높게 나타났으며, 이러한 광미가 바람이나 강우에 의해 광미댐 하부에 있는 농경지나 하천으로 유입되어 주변 환경을 오염시킬 가능성이 크므로 이들 토양, 농작물, 자연수 시료들에 대한 화학분석자료를 바탕으로 인체위해성평가 모델링을 실시하였다. 폐금속광산 지역에서의 인체노출경로는 농사활동을 통한 토양의 섭취, 지하수(식수)의 섭취, 쌀의 섭취, 농사활동에 의한 토양의 피부접촉, 목욕에 의한 지하수의 피부접촉 등 5가지로 파악할 수 있었다. 각 노출경로별 비발암성위해도 평가 결과, 모든 광산에서 지하수를 식수로 섭취하는 노출경로와 쌀의 섭취를 통해 비소의 독성위해도가 가장 높은 것으로 나타났다. 특히, 동일광산과 옥동광산에서는 HI지수가 7.0 이상으로, 화천광산의 경우는 5.0 이상으로 매우 높게 나타나 이들 지역 주민들의 비소의 독성위해성이 높았다. 비소에 대한 발암위해도 평가 결과, 동일광산, 옥동광산 및 화천광산 지역의 쌀 섭취의 노출경로를 통한 비소에 의해 암이 발생할 확률은 만명중의 5명에서 8명 정도로 높게 나타났다. 지하수를 식수로 섭취하는 경우, 비소의 발암위해도도 이들 광산지역에서 만명중의 1명보다 높게 나타났다. 이는 미국 EPA에서 제시한 초과발암위해도보다도 크므로 이들 지역 주민들이 비소에 의해 오염된 농작물(쌀)이나 지하수를 식수로 지속적으로 장기간 섭취하게 된다면 비소가 건강에 미치는 위해영향이 크다고 판단된다.warfarin 용량 조절에 유용할 것으로 생각된다.대한 치료 순응도가 높아졌다. 후 동율동 전환율이나 좌심방 수축능 회복에 좋은 결과를 보여주었다 그러나 향후 대상환자들에 대한 중장기적인 추적 관찰이 필요하리라 생각한다.pm1.6$일째에 관상동맥조영술을 시행하여 모든 도관의 개존율$(100\%=57/57)$을 확인하였다 수술 전 중재 술을 시행한 1개소에서는 중재술 부위의 재협착소견이 보여 수술 후 조영술시 재풍선확장술로 치료하였다. 수술 후 추적관찰(평균 $25\pm26$개월)동안 1예에서 심부전으로 사망하였다. 생존한 환자 24예에서 술 후 평균 $9.6\pm3$개월째에 관상동맥조영술을 시행하였고 이식도관이 string 징후를 보인 1예를 제외하고 모두 개존(56/57)되어 있었으며, 약물용출형 스탠트를 시행하기 이전의 12예의 중재술 중 2예에서 $50\%$ 이상의 스텐트 협착이 있었으나 흉통의 재발은 없었다. 결론: 하이브리드 관상동맥 우회 술은 수술위험도를 낮추기 위하여 최소절개 관상동맥우회술과 병합하여 시도될 수 있을 뿐 아니라, 선택적 환자들에서는 정중 흉골절개 관상동맥우회술과 병합하여 수술관련 유병률을 낮추고 심근의 완전 재관류화를 도모할 수 있었다.호도에서 가장 적절한 방법으로 사료된다.비위생 점수가 유의적으로 높은 점수를 나타내었다. 조리종사자의 위생지식 점수와 위생관리 수행수준의 상관관계를 조사한 결과, 위생지식의 기기설비위생은 위생관리 수행수준의 합계(p<0.01)에서 유의적인 상관관계(p<0.01)를 나타내었으며, 위생지식의 식중독 및 미생물은 위생관리 수행수준의 개인위생( Environmental survey from some abandoned metal mine areas was undertaken on to assess the risk of adverse health effects on human exposure to arsenic influenced by past Au-Ag mining activities. Elevated levels of As were found in tailings from the studied mine areas. This high concentration may have a impact on soils and waters around the tailing piles. In order to perform the human risk assessment, chemical analysis data of soils, rice grains and waters fur As have been used. The HQ values fer As via the rice grain and groundwater consumption were significantly higher compared with other exposure pathways in all metal mine areas. However, there were minimal soil and water dermal contact risks. The resulting Hl values of As from the Dongil, Okdong and Hwacheon mine areas were higher than 5.0, and their toxic risk due to drinking water and rice grain was strong in these mine areas. The cancer risk of being exposed to As by the rice grain route from the Dongil, Okdong and Hwacheon mine areas was $5.2\times10^{-4},\;6.0\times10^{-4}\;and\;8.1\times10^{-4}$, respectively. The As cancer risk via the exposure pathway of drinking water from these mine areas exceeded the acceptable risk of 1 in 10,000 fer regulatory purposes. Thus, the daily intakes of groundwater and rice grain by the local residents from the Dongil, Okdong and Hwacheon mine areas can pose a potential health threat if exposed by long-term arsenic exposure.

학술자료 II - 고양이의 레트로바이러스(하)

이진수,Lee, Jin-Su 대한수의사회 2009 대한수의사회지 Vol.45 No.9

충주지역 흑색셰일 분포지역에서의 잠재적 독성원소들의 분산과 부화

이진수,전효택,김경웅,Lee, Jin-Soo,Chon, Hyo-Taek,Kim, Kyoung-Woong 대한자원환경지질학회 1996 자원환경지질 Vol.29 No.4

This study had three purposes: (1) to investigate dispersion and enrichment level of potentially toxic elements; (2) to identify uranium-bearing minerals in black shales; and (3) to assess the chemical speciation of heavy metals in soils and sediments. Rock, surface soil and stream sediment samples were collected in the Chungjoo area covered with black shales in Korea. These samples were analyzed for multi-elements using INAA and ICP-AES. The maximum abundance of U in black shales is 56 ppm and radioactivity counts up to 240CPM. Molybdenum, V, Ba, Cu, and Pb are enriched in black shales and most of soils show high concentrations of U, Mo, Ba, Cu, Pb and Zn. Concentrations of potentially toxic elements decrease in the order of mountain soil > farmland soil > paddy soil. Enrichment index of soils and sediments are calculated and higher than 1.0 in the black shale area with the highest value of 6.1. In order to identify U-bearing minerals, electron probe micro analysis was applied, and uraninite and brannerite in black shale were found. Uraninite grains are closely associated with monazite or pyrite with the size of $2{\mu}m$ to $10{\mu}m$ in diameter whereas brannerite occurs as $50{\mu}m$ euhedral grains. With the results of sequential extraction scheme, residual fractions of Cu, Pb and Zn in soils are mainly derived from weathering of black shale but Cu, Pb and Zn in sediments are present as non-residual fractions. Lead is predominantly present as oxidizable phase in soils whereas Zn is in exchageable/water-acid soluble phase in sediments.