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이주호,우홍균,김학재,김동완,이세훈,김태민,김영환,허대석 대한암학회 2012 Cancer Research and Treatment Vol.44 No.4
Purpose The current study was conducted in order to evaluate the clinical outcome of radical radiotherapy (RT) with or without chemotherapy for elderly patients with stage III non-small cell lung cancer (NSCLC). Materials and Methods Between 1990 and 2010, 125 patients, aged 70 years or more, received radical RT with or without chemotherapy for treatment of stage III NSCLC. We reviewed the patients’prognostic factors, including comorbidities. Comorbidity status was evaluated using a simplified comorbidity score (SCS). Of the patients reviewed, 82 received radical RT alone,whereas the other 43 patients underwent chemoradiotherapy (CRT). A platinum-based chemotherapy regimen was most commonly used (42/43). Results The two-year overall-survival (OS) and progression-free survival (PFS) rates were 32.2%and 21.8%, respectively. SCS was the independent prognostic factor for OS. In the frail elderly subgroup with a SCS of ≥10, CRT demonstrated a significant difference in PFS, but not in OS. In contrast, OS and PFS following CRT were significantly superior to RT in the fit elderly subgroup with a SCS of <10. The incidence of severe pulmonary toxicities in the frail elderly subgroup was significantly higher than that in the fit elderly subgroup. Conclusion Multiple comorbidities evaluated according to the SCS are related to poor OS in elderly patients with stage III NSCLC. CRT improved clinical outcome when compared to RT in the fit elderly subgroup, however, the gain from this treatment was negated in the frail elderly subgroup with multiple comorbidities. Therefore, evaluation of comorbidity is necessary in order to determine whether chemotherapy should be combined with RT in elderly patients with stage III NSCLC.
음악줄넘기 운동이 아동 신체활동의 즐거움 및 자아실현에 미치는 영향
이주호,민현주 한국무용학회 2008 한국무용학회지 Vol.8 No.1
본 연구의 목적은 음악줄넘기 운동이 아동 신체활동의 즐거움 및 자아실현에 어떤 영향을 미치는지 실험적으로 검증하는데 그 목적을 두었다. 본 연구의 대상은 정선군에 소재하고 있는 음악줄넘기를 참여한 초등학교 5개 학교의 학생 200명과 음악줄넘기를 참여하지 않고 정규체육수업을 실시한 초등학교 5개 학교의 학생 200명을 대상으로 하였으며, 총 400명을 주 1회씩 11주간 음악줄넘기를 실시하였다. 본 연구에 사용한 통계분석은 인구사회학적 특성에 따른 즐거움 및 자아실현의 차이를 검증하기 위하여 일원변량분석(one-way ANOVA)를 실시하였고 참여수준과 즐거움 및 자아실현의 관계를 검증하기 위하여 공변량분석(ANCOVA)을 실시하였다. 첫째, 음악줄넘기는 인구사회학적 특성과 즐거움 및 자아실현을 보면 즐거움은 성에서 남학생이 긍정적인 영향을 미쳤고, 학년에서는 5학년이 긍정적인 영향을 미쳤다. 자아실현은 성에서 여학생이 긍정적인 영향을 미쳤고, 학년에서는 6학년이 긍정적인 영향을 미쳤다. 둘째, 음악줄넘기는 참여수준과 즐거움 및 자아실현의 관계에서 보면 즐거움에서 참여가 긍정적인 영향을 미쳤으며 자아실현에서도 참여가 긍정적인 영향을 미쳤다. The purpose of this study is to experimentally verify what kind of effect rope jumping with music has on pleasure and self-realization of children's physical activities. The subjects of the study were 200 students from 5 elementary schools in Jeongseon-gun who participated in rope jumping with music in the past and 200 more students from 5 elementary schools who participated in normal physical training classes instead of rope jumping with music. The total of 400 students performed rope jumping once a week for 11 weeks. As to the statistical analysis used in this study, one-way ANOVA was performed in order to verify the differences in pleasure and self-realization depending on the characteristics of sociology of population and ANCOVA was performed to examine the relation of the level of participation with pleasure and self-realization. First, in the differences in pleasure and self-realization depending on the characteristics of sociology of population, rope jumping with music had more positive effect on the pleasure of male students and of the students of 5th grade and on the self-realization of female students and of the students of 6th grade. Second, in the relation of the level of participation with pleasure and self-realization, participation in rope jumping with music had positive effect on both pleasure and self-realization. Through this study, we came to know that rope jumping with music has a positive effect on pleasure and self-realization of children's physical activities.