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이승우,이상학,여동승,이숙영,김석찬,김관형,문화식,송정섭,박성학,정은선,Lee, Seung-Woo,Lee, Sang-Haak,Yeo, Dong-Seung,Lee, Sook-Young,Lee, Seok-Chan,Kim, Kwan-Hyoung,Moon, Hwa-Sik,Song, Jeong-Sup,Park, Sung-Hak,Jung, Eun-Sun 대한결핵및호흡기학회 2002 Tuberculosis and Respiratory Diseases Vol.53 No.6
Amiodarone 폐독성은 약제 복용력이 있는 환자에서 새로운 증상과 X-선의 변화가 있을 때 의심하여야 하며 울혈성 심부전이나 폐감염증, 폐색전증, 악성종양 등과 감별하는 것이 중요하다. 진단은 임상적, 방사선학적, 조직학적 소견을 종합하여 내릴 수 있으며 대부분의 경우에는 약제 중단을 통해서 폐독성의 호전을 기대할 수 있으나 일부에서는 호흡부전으로 진행하거나 기존의 심부정맥의 재발 등으로 인하여 사망하는 경우도 있다. 저자들은 심부정맥으로 amiodarone을 사용하던 환자에서 치명적인 폐독성이 발생한 4예를 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다. The lungs are frequently the site of adverse drug reactions because of their higher oxygen concentration, the distinctive properties of the pulmonary circulation, and the close proximity of the alveolar epithelium to the blood. Amiodarone, an iodinated benzofuran derivative, is an effective antiarrhythmic drug commonly used for refractory tachyarrhythmia. However, it has a wide range of adverse effects, the most serious of which is lung disease. Most patients present with the insidious onset of dyspnea and a nonproductive cough, and generally recover after withdrawing the drug. We recently experienced four fatal cases of amiodarone pulmonary toxicity. Therefore, we discuss these unusual drug-induced pulmonary toxicity cases with a review of the relevant literature.
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이승우,고홍섭,이상구,Lee, Sung-Woo,Kho, Hong-Seop,Lee, Sang-Goo 대한안면통증구강내과학회 1999 Journal of Oral Medicine and Pain Vol.24 No.2
Aucubin, the natural product, which is isolated from Aucuba japonica, has a variety of pharmacological effects such as liver-protective function, inhibition of liver RNA and protein biosynthesis, hypotensive activity and antimicrobial effect, etc. This study was performed to investigate the effects of iridoid compounds on wound healing. The author prepared 0.1% aucubin solution and 0.1% aucubin ointment as an active form, aucubigenin to which aucubin was converted by ${\beta}$-glucosidase. Artificial surgical wound was made on either 1cm lateral side of the dorsal midline along the axis of spine of Sprague-Dawley rats under sterile technique. Application of 0.1% aucubin solution or 0.1% aucubin ointment to surgical wound was done daily. Light microscopic examination was performed on the postsurgical 3 days, 5 days, and 9 days. The 0.1% aucubin solution group epithelialized earlier than the control group and the fibrosis of granulation tissue of both aucubin groups were more prominent than the control group. Collectively, this study suggests the possibility of aucubin as a topical agent. Further research should be performed on the mechanism of aucubin on wound healing and proper formulation for effective topical agents.
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컴퓨터 발전 초기과정에 영향을 준 수학자들에 관한 고찰
이승우,Lee, Seung-Woo 한국수학사학회 2014 Journal for history of mathematics Vol.27 No.4
Computer is a modern day invention integrated with mathematics, engineering, and logics. The purpose of this study is to examine mathematicians' roles and influences on the invention, establishment, and developments of computers, particularly in the areas of hardware and software, and to emphasize the importance of mathematics on the computer sciences. To implement these purposes, this study firstly examines the mathematicians based on the period. Secondly from the mathematicians' roles in the development of programming, the correlation between mathematics and computers has been investigated. Finally, mathematicians who gave influence on establishing the current development of computer science are highlighted.
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탄산화 및 저온 결정화를 통한 나트륨 농축수로부터 나트륨 화합물 합성
이승우,채수천,방준환,Lee, Seung-Woo,Chae, Soochun,Bang, Jun-Hwan 한국자원리싸이클링학회 2020 資源 리싸이클링 Vol.29 No.4
Carbonation (step I) and cryo-crystallization (crystallization at low temperature) (step II) were performed to synthesize Na compounds from sodium concentrated solution. In the step 1, the solubility and pH of carbon dioxide (95 wt.%) affecting carbonation could be changed by the variation of reaction temperature. The step II was performed at 2 ℃ after carbonation. The injection of carbon dioxide was carried out twice for the stable production and the saturated solubility of carbonate ions in solution. Firstly, we tried to inject CO<sub>2</sub> for controlling the solubility of CO<sub>2</sub> by changing the reaction temperature from 35 ℃ to 10 ℃, and the second injection was aimed at 10 ℃ for inducing nucleation of Na compound through carbonation after NaCl solution addition. In the cryo-crystallization step, the crystal growth of Na compounds could be induced by slowing the carbonation rate through reaction temperature change from 10 ℃ to 2 ℃. In this study, the effect on NaOH concentration was examined and the purity of Na compound was increased when 2M NaOH was used. In addition, the synthesized Na compounds were mostly rod-shaped and consisted of sodium carbonate or sodium carbonate with monohydrate.
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이승우,Lee, Seung-Woo 한국데이터정보과학회 2012 한국데이터정보과학회지 Vol.23 No.3
본 연구에서는 S/W와 H/W 전공자들의 취업률 향상을 목적으로, 첫째, S/W와 H/W 전공자들이 선호하지 않는 전공분야에 취업 관심도를 높이고 학습자의 역량을 발전시켜 다양한 전공분야로 취업을 도모하기 위한 교육사례를 제시하였고, 둘째, 향후 S/W와 H/W 분야에서 학과차원의 특수성과 실정을 반영한 취업률 향상 추진 방안에 관하여 제안하였다. 이를 위하여 S/W와 H/W의 학과별 4학년 40명씩을 대상으로 비선호 전공분야에서 도구로서 활용하는 확률/통계 교육내용의 이해도를 설문조사를 통하여 파악하였고, 취업률 제고를 위하여 취업선호도 사전설문조사, 확률/통계를 연계한 전공수업, 취업선호도 사후설문조사 총 3단계를 거쳐 취업인식이 변화됨을 살펴보았다. 또한 이 전공수업은 학습자의 학업성취도에 미치는 효과에 대해 다중회귀분석을 실시하여 검증하였다. The purpose of this study is to increase the employment rate of graduates in the fields of the S/W and H/W. In order to seek employment in various major fields of the S/W and H/W, firstly, this paper proposes the educational case study that increases the concern about employment and develops learner's ability in the unfavorable major fields. Secondly, this paper presents the future driving improvement for the employment rate on the basis of the department's special characteristics and the actual circumstances in the fields of the S/W and H/W. This paper conducts the surveys of each 40 seniors majoring in S/W and H/W respectively in order to measure the understanding of probability/statistics which has been used as tools in the unfavorable major fields. With the purpose of increasement on the employment rate, the paper is designed to have 3 steps, that is, a preliminary questionnaire for employment preference, major courses connecting probability/statistics and a post-questionnaire for employment preference, which eventually investigates the changes of the perception on employment. This paper is verified by the multiple regression analysis to approve the effect on improving learner's academic achievement.
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이승우,김영걸,이충화,변재경,Lee, Sung Woo,Kim, Young Kul,Lee, Choong Hwa,Byun, Jae Kyoung 한국산림과학회 2001 한국산림과학회지 Vol.90 No.4
산퇴적물에 대한 산림토양의 산성화 민감도를 평가하기 위하여 4개 지역 소나무림을 대상으로 토양내 추출성 황산이온 함량과 황산이온 흡착능을 정량하였다. 유기물층의 수용성 황산이온 함량은 강화와 홍천에 비해 울산과 남산에서 현저히 높아 황산화물의 지역적 유입특성을 반영하였다. 그러나 광물질 토양내 추출성 황산이온 함량은 황산화물의 유입량과 토양 흡착능의 상호작용으로 울산, 강화, 남산 및 홍천 순으로 높게 나타났다. 대기오염 우려지역인 남산, 강화 및 울산의 황산이온 특정흡착률(총 추출성에 때한 불용성의 비율)은 각각 16.6%, 56.8% 및 37.4%로써 산퇴적물에 대한 토양산성화의 상대적 민감도는 남산에서 가장 높았다. 황산이온 흡착등온식($RE=mX_i-b$)의 추가유입량($X_i$)과 흡착량(RE)간의 정의 상관성은 광물질 토양에서만 유의적으로(p<0.05) 나타났다. 흡착등온식의 회귀계수(m)로 나타낸 토심 30cm까지의 황산이온 흡착능은 남산, 강화, 울산 및 홍천에서 각각 0.16, 0.24, 0.25 및 $0.32mmol_c\;kg^{-1}$으로 이에 근거한 지역별 토양산성화 민감도는 남산에서 가장 높았다. 황산이온 영점흡착량(null-point adsorption)은 남산, 강화, 울산 및 홍천에서 각각 3.81, 2.17, 4.96 및 $0.65mmol_c\;kg^{-1}$으로 홍천을 제외한 나머지 지역은 현실적인 황산이온 퇴적량을 훨씬 초과하는 추정치이었다. The extractable sulfate content and sulfate adsorption capacity in soils of four Pinus densiflora stands were measured to assess the soil acidification sensitivity to acid deposition. The soluble sulfate content in organic horizon which reflects the previous deposition of sulfur oxides was much higher for Namsan and Ulsan than Kanghwa and Hongcheon. In mineral soils, however, the extractable sulfate content was the greatest for Ulsan followed by Kanghwa, Namsan and Hongcheon due to the interactive effect of previous deposition and soil adsorption of sulfate. Adsorption rates of specifically adsorbed sulfate(proportion of insoluble sulfate to total extractable sulfate) for Namsan, Kanghwa and Ulsan affected by acid deposition were 16.6%, 56.8% and 37.4%, respectively, so that the soil in Namsan had the highest acidification sensitivity to acid deposition. For sulfate adsorption isotherm($RE=mX_i-b$), the significantly positive correlations between added sulfate($X_i$) and adsorbed sulfate(RE) were found only in mineral soil(p<0.05) over all regions. The regression coefficient(m) that means soil sulfate adsorption capacity by 0-30cm depth was 0.16, 0.24, 0.25 and 0.32 in $mmol_c\;kg^{-1}$ for Namsan, Kanghwa, Ulsan and Hongcheon, respectively, indicating that soil acidification sensitivity is the highest for Namsan. The added sulfate($X_i$) that could make the adsorbed sulfate(RE) null was 3.81, 2.17, 4.96 and 0.65 in $mmol_c\;kg^{-1}$ for Namsan, Kanghwa, Ulsan and Hongcheon, respectively and the values of former three regions considerably exceeded the realistic sulfate deposition.
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이승우,Lee, Seung-Woo 대한한방내과학회 1991 大韓韓方內科學會誌 Vol.12 No.1
The following results were obtained according to these fact which is considered peviodically and bibliographically ; 1. The cause of bleeding of cough was Oegampunghan(外感風寒), Pyosaoesok(表邪外束), Chohwasangpye(燥火傷肺) in external cause, Eumhuhwadong(陰虛火動), Sinhu(腎虛), Hyulhu(血虛), Damhwajukyul(痰火積熱), Pyesuyul(肺受熱) ect. in internal cause. 2. The symptoms of bleeding of cough because of external cause was similar to generally cold symptom, because of internal cause were similar to Yeumhuhwadong(陰虛火動) and generanl Huyul(虛熱) symptom. 3. The treatment of external were Mahwangtang, Soshihotang, Sabaeksan ect. internal were Samultang, Yookmijihwangtang, Jaeumganghwatang, Gesosan ect.
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