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지구자(枳?子) 산청목(山靑木) 배합(配合)이 D-galactosamine 유발 백서의 간손상에 미치는 영향(影響)
이선아,문구,Lee, Seon-A,Moon, Goo 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.1
Objectives : This study was carried out to investigate the hepatoprotective effects of mixture with Hovenia dulcis Thunb (HDT) and Acer tegmentosum Maxim(ATM) on D-galactosamine-induced liver failure in rats. Methods : The animals were divided into 4 groups: control, with liver failure and no treatment; H1A1, with liver failure and oral treatment with HDT 1 and ATM 1; H1A2, with liver failure and oral treatment with HDT 1 and ATM 2; H1A4, with liver failure and oral treatment with HDT 1 and ATM 4. The animals were treated for 3 weeks and then examinations of change of body weight, aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma glutamyl transpeptidase ($\gamma$-GTP), total cholesterol, triglyceride, total bilirubin, superoxide dismutase (SOD), catalase, histopathologic change, and complete blood count (CBC) were performed. Results : All experimental groups had significantly decreased AST in serum and markedly increased activity of SOD as compared with the control group. H1A1, and H1A4 significantly decreased ALT in serum and H1A4 at 2 weeks was significantly higher on the change of body weight as compared with the control group. In histopathologic change of liver tissue by light microscopy, all experimental groups showed recovery effects of liver cells which were damaged by D-galactosamine. Conclusions : Based upon these results, it could be assumed that a mixture of HDT and ATM has hepatoprotective and antioxidative effects on D-galactosamine-induced liver failure. Therefore, a mixture of HDT and ATM might be utilized as a protective agent in therapy for liver diseases.
부분 무치악 임플랜트 보철 수복시 자연치와의 비고정성 연결형태에 따른 3차원 유한요소법적 연구
이선아,정재헌,Lee, Seon-A,Chung, Chae-Heon 대한치과보철학회 1996 대한치과보철학회지 Vol.34 No.1
In this study, we designed the finite element models of mandible with varying their connecting types between the prosthesis on implant fixture and 2nd premolar, which were free-standing case(Mf), precision attachment case(Mp), semiprecision attachment case(Ms) and telescopic case(Mt). The basic model of the designed finite element models, which contained a canine and the 1st & 2nd premolar, was implanted in the edentulous site of the 1st & 2nd molar by two implant fixtures. We applied the load in all models by two ways. A vertical load of 200N was applied at each central fossa of 2nd premolar and 1st implant. A tilting load of 20N with inclination of $45^{\circ}$ to lingual side was applied to buccal cusp tips of each 2nd premolar and 1st implant. And then we analyzed three-dimensional finite element models, making a comparative study of principal stress and displacement in four cases respectively. Three-dimensional finite element analysis was performed for the stress distribution and the displacement using commercial software(IDEAS program) for SUN-SPARC workstation. The results were as follows : 1 Under vertical load or tilting load, maximum displacement appeared at the 2nd premolar. Semiprecision case showed the largest maximum displacement, and maximum displacement reduced in the order of precision attachment, free-standing and telescopic case. 2. Under vertical load. the pattern of displacement of the 1st implant appeared mesio-inclined because of the 2nd implant splinted together. But displacement pattern of the 2nd premolar varied according to their connection type with prosthesis. The 2nd premolar showed a little mesio-inclined vertical displacement in case of free-standing and disto-inclined vertical displacement due to attachment in case of precision and semiprecision attachment. In telescopic case, the largest mesio-inclined vertical displacement has been shown, so, the 1st premolar leaned mesial side. 3. Under tilting load, The pattern of displacement was similar in all four cases which appeared displaced to lingual side. But, the maximum displacement of 2nd premolar appeared larger than that of the first implant. Therefore, there was large discrepancy in displacement between natural tooth and implant during tilting load. 4. Under vertical load, the maximum compressive stress appeared at the 1st implant's neck. Semiprecision attachment case showed the largest maximum compressive stress, and the maximum compressive stress reduced in the order of precision attachment, telescopic and free-standing case. 5 Under vertical load, the maximum tensile stress appeared at the 2nd implant's distal neck. Semiprecision attachment case showed the largest maximum tensile stress, and the maximum tensile stress reduced in the order of precision attachment, telescopic and free-standing case. 6. Under vertical load or tilting load, principal stress appeared little between natural tooth & implant in free-standing case, but large principal stress was distributed at upper crown and distal contact site of the 2nd premolar in telescopic case. Principal stress appeared large at keyway & around keyway of distal contact site of the 2nd premolar in precision and semiprecision attachment case, appearing more broad and homogeneous in precision attachment case than in semiprecision attachment case.
한(韓).중(中) 양국(兩國)의 전통사회(傳統社會)에 있어서의 의원(醫員)의 사회적(社會的) 지위(地位)
이선아,Lee, Seon-A Korean Institute of Oriental Medicine 2003 한국한의학연구원논문집 Vol.9 No.2
這篇文章是關丁韓中兩國傳統社會襄醫員的社會地位的論文. 在這篇文章通過韓中兩國社會的區別点來析韓中兩國傳統社會醫員的地位. 結論就是韓國傳統社會比中國傳統社會還閉鎖, 而韓國傳統社會醫員的社會的地位比中國還底一些.
대학교 학생식당의 실내소음 실태 및 원인 분석 사례연구
최윤정,이선아,김혜경,Choi, Yoon-Jung,Lee, Seon-A,Kim, Hye-Kyeong 한국주거학회 2007 한국주거학회 논문집 Vol.18 No.5
This is a case study for improving the sound environmental quality of cafeteria in university campus. The purpose of the study is to find out the present condition of physical level, type, and cause of indoor noise of cafeteria in university campus by comparison with a restaurant near campus. Research methods were field survey and questionnaire survey. Field survey was consisted of measurement on equivalent and instant noise level and observation on noise type. Respondents of questionnaire survey were 60 students using subject cafeteria or restaurant. Surveys were carried out in the 8th and in the 14th of December 2005. The results are as follows. 1) Indoor noise levels of the cafeteria were measured as $67.2{\sim}76.6$ (average 73.3) dB(A)Leq5min and $60.3{\sim}90.5$ (average 71.2) dB (A), exceeded the indoor noise recommended value of ASHRAE (American Society of Heating, Refrigerating and Air Conditioning Engineers). But noise levels of the restaurant were $61.6{\sim}70.4$ (average 66.9) dB(A)Leq5min and $59.8{\sim}70.6$ (average 64.9) dB(A). 2) The users's responses on major noise type in the cafeteria were 'noise by handling equipment and tableware', 'noise by moving chairs', and 'talcing noise', but 'taking noise' and 'background music' in the restaurant. 3) It was found that indoor noise level of the cafeteria was caused by sound reflection of finishing materials, noise diffusion by open type kitchen, and dragging noise of movable furniture.
이선아(Lee Seon-a),김범석(Kim Beom Seok),이혜인(Lee Hye in),박원형(Won hyung Park) 한국정보통신학회 2021 한국정보통신학회 종합학술대회 논문집 Vol.25 No.2
제로 트러스트 보안을 바탕으로 기존 기업보안시스템의 한계를 강화하는 방안을 제시한다. 4차 산업혁명 시대가 도래하면서 보안의 패러다임도 바뀌고 있다. 클라우드 컴퓨팅과 COVID-19로 인해 원격 근무가 활발해지면서 변화된 IT 환경에서 발생하는 보안 문제에 대한 이슈가 제고된다. 동시에 공격기법들도 지능화되고 고도화되는 현 상황에서 기업에서는 제로 트러스트 보안을 활용해 현재의 보안 시스템을 더 강화해야 한다. 제로 트러스트 보안은 모든 것을 의심하고 신뢰하지 않는다는 핵심 개념을 토대로 모든 데이터 통신을 감시하고, 접근 요청자에 대한 엄격한 인증과 최소한으로 접근 권한을 허용함으로써 보안성을 높인다. 따라서, 본 논문에서는 기존 보안 시스템을 강화하는 제로 트러스트 보안 솔루션을 소개하고, 기업에서 도입해야 하는 방향성과 타당성을 제시한다. It proposes a plan to strengthen the limitations of existing corporate security systems based on Zero-Trust. With the advent of the era of the Fourth Industrial Revolution, the paradigm of security is also changing. As remote work becomes more active due to cloud computing and COVID-19, security issues arising from the changed IT environment are raised. At the same time, in the current situation where attack techniques are becoming intelligent and advanced, companies should further strengthen their current security systems by utilizing zero trust security. Zero-trust security increases security by monitoring all data communications based on the concept of doubting and trusting everything, and allowing strict authentication and minimal access to access requestors. Therefore, this paper introduces a zero trust security solution that strengthens the existing security system and presents the direction and validity that companies should introduce.