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마우스에 있어서 Diethylstilbestrol의 免疫毒性에 미치는 紅蔘 Ethanol 抽出物의 影響
이덕행,안영근 원광대학교 식품약품안전성연구소 1991 食品藥品安全性硏究 Vol.4 No.-
The effect of red ginseng ethanol extract on the inninotoxicity of diethylstilbestrol (DES) was studied in ICR mice. ICR male mice were divided into 5 groups (10mice/group), and red ginseng ethanol extract(50, 100 and 200 ㎎/㎏ body wt., respectively) and DES (1㎎/㎏ boky wt.) were injected intraperitoneally (i.p.) to ECR mice once a day for 2 weeks. Mice wre sentitized and challenged with sheep red blood cells(S-RBC). Immune response were evaluated by humoral immunity, cell-meiated immunity, non-specific immunity, and circulating leukocyte counts. The results of this study were summarized as followings: 1. The DES-treated control group as compared with normal group showed the tendency to decrease body weight rate and relative liver weight, decreased both humoral and cellular immune responses, phagocyte activity, and circulating leudocyte counts, but increased the natural killer (NK) cell activity. 2. Compared with the DES-treated control group, DES plus red ginseng ethanol extract-treated groups significantly decreased the body weight rate(P<0.01). Rclative liver weight was significantly decreased in DES plus RED ginseng ethanol extract (50㎎/㎏)-treated group (P<0.01), but significantly increased in DES plus red ginseng ethanol extract (100㎎/㎏)-treated group (P<0.01). Relative spleen and thymus weights were significantly enhanced in DES plus red ginseng ethanol extract (100㎎/㎏)-treated group(P<0.01), but significantly decreased in DES plus red ginseng ethanol extract (200㎎/㎏)-treated group(P<0.01) 3. Both humoral and cellular immune responses were significantly decreased in DES plus red ginseng ethanol extract-treated groups rather than in the DES-treated control group(P<0.01). Especially, it weakened the decrease in DES plus red ginseng ethanlo extract (100㎎/㎏)-treated group. 4. Phagocyte activity and circulating leudocyte counts were significantly decreased in DES plus red ginseng ethanol extract-treated groups rather than in the DES-treated control group (P<0.01). Especially, it weakened the decrease in DES plus red ginseng ethanol extract (100㎎/㎏)-treated group (P<0.01), but significantly decreased in DES plus red ginseng ethanol extract (50 and 200 ㎎/㎏)-treated groups (P<0.01).
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마우스에 있어서 Diethylstilbestrol의 免疫毒性에 미치는 紅蔘 Ethanol 抽出物의 影響
이덕행,안영근 한국환경독성학회 1991 환경독성보건학회지 Vol.6 No.1
The effect of red ginseng ethanol extract on the immunotoxicity of diethylstilbestrol (DES) was studied in ICR mice. ICR male mice were divided into 5 groups (10 mice/group), and red ginseng ethanol extract (50, 100 and 200 mg/kg body wt., respectively) and DES (1 mg/kg body wt.) were injected intraperitoneally (i.p.) to ICR mice once a day for 2 weeks. Mice were sensitized and challenged with sheep red blood cells (S-RBC). Immune response were evaluated by humoral immunity, cell-mediated immunity, non-specific immunity, and circulating leukocyte counts. The results of this study were summarized as followings: 1. The DES-treated control group as compared with normal group showed the tendency to decrease body weight rate and relative liver weight, decreased both humoral and cellular immune responses, phagocyte activity, and circulating leukocyte counts, but increased the natural killer (NK) cell activity. 2. Compared with the DES-treated control group, DES plus red ginseng ethanol extract-treated groups significantly decreased the body weight rate (P<0.01). Relative liver weight was significantly decreased in DES plus red ginseng ethanol extract (50 mg/kg)-treated group (P<0.01), but significantly increased in DES plus red ginseng ethanol extract (100 mg/kg)-treated group (P<0.01). Relative spleen and thymus weights were significantly enhanced in DES plus red ginseng ethanol extract (100 mg/ kg)-treated group (P<0.01), but significantly decreased in DES plus red ginseng ethanol extract (200 mg/kg)-treated group (P<0.01). 3. Both humoral and cellular immune responses were significantly decreased in DES plus red ginseng ethanol extract-treated groups rather than in the DES-treated control group (11<0.01). Especially, it weakened the decrease in DES plus red ginseng ethanol extract (100 mg/kg)-treated group. 4. Phagocyte activity and circulating leukocyte counts were significantly decreased in DES plus red ginseng ethanol extract-treated groups rather than in the DES-treated control group (P<0.01). Especially, it weakened the decrease in DES plus red ginseng ethanol extract (100 mg/kg)-treated group. NK cell activity was significantly enhanced in DES plus red ginseng ethanol extract (100 mg/kg)-treated group (P<0.01), but significantly decreased in DES plus red ginseng ethanol extract (50 and 200 mg/kg)-treated groups (P<0.01).
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Thermal Analysis of MIRIS Space Observation Camera for Verification of Passive Cooling
이덕행,한원용,문봉곤,박영식,정웅섭,박귀종,이대희,표정현,김일중,mingyukim,toshiomatsumoto 한국우주과학회 2012 Journal of Astronomy and Space Sciences Vol.29 No.3
We conducted thermal analyses and cooling tests of the space observation camera (SOC) of the multi-purpose infrared imaging system (MIRIS) to verify passive cooling. The thermal analyses were conducted with NX 7.0 TMG for two cases of attitude of the MIRIS: for the worst hot case and normal case. Through the thermal analyses of the flight model, it was found that even in the worst case the telescope could be cooled to less than 206°K. This is similar to the results of the passive cooling test (~200.2°K). For the normal attitude case of the analysis, on the other hand, the SOC telescope was cooled to about 160°K in 10 days. Based on the results of these analyses and the test, it was determined that the telescope of the MIRIS SOC could be successfully cooled to below 200°K with passive cooling. The SOC is, therefore, expected to have optimal performance under cooled conditions in orbit.
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이덕행,문봉곤,박영식,이대희,정웅섭,이창희,남욱원,박성준,표정현,차상목,가능현,박장현,선광일,이승우,박종오,이형목,Matsumoto, Toshio,한원용 한국우주과학회 2011 한국우주과학회보 Vol.20 No.1
System(MIRIS)는 한국천문연구원이 개발하고 있는 소형 적외선 우주망원경이다. MIRIS는 적외선 센서의 열잡음을 최소화시키기 위하여 망원경의 온도가 허용범위를 넘지 않도록 설계되었다. 특히 3K의 심우주를 향해 MIRIS의 복사열을 자연 방출하는 Passive cooling은 임무 성공에 영향을 미치는 매우 중요한 과정이다. 이를 검증하고자 NX 7.0(Space Systems Thermal, TMG 탑재)을 사용하여 열 해석을 수행하였다. 각 부품별로 물성과 열광학 특성을 적용하여 전도 및 복사를 통한 열전달 과정을 계산하였고, MIRIS의 궤도 특성을 고려하여 정상상태에서의 망원경 온도를 얻었다. 그 결과 Passive cooling을 통해 MIRIS 망원경이 허용범위 아래로 냉각되는 것을 확인하였다.
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허덕행(Duckhaing Hu),정원창(Wonchang Jeong),임관철(Kwanchul Im) 융복합지식학회 2021 융복합지식학회논문지 Vol.9 No.4
대부분의 중소기업은 생산성 및 제조 경쟁력을 높이기 위해 스마트 설비 도입을 검토하고 있으나, 투자할 여유가 부족하여 스마트공장으로 전환하기가 어려운 상황이다. 하지만 최근 발주업체가 생산현황, 불량률 등의 정보를 요구함에 따라 중소기업은 신뢰성을 확보하기 위해 스마트공장 구축의 필요성을 느끼고 있다. 따라서 본 논문에서는 CNC 설비를 목표로 전력데이터를 이용한 설비 모니터링 시스템을 설계 및 구현하여 중소기업의 스마트공장 구축을 지원하고자 하였다. 개발된 시스템은 IoT센서 디바이스로부터 수집된 설비에 공급된 전력 시계열 데이터를 이용하여 생산 설비의 작동에 필요한 전력의 이상 변화치를 검출하여 향후 전력 이상 변화치와 생산 품목별 품질 요소간의 연관 관계를 밝힐 수 있는 기반을 제공함으로 거의 모든 현장에서 쉽게 측정 가능한 전력 측정으로 생산성 향상시킬 수 있다. Most of the small and medium-sized manufacturing companies are considering the introduction of smart facilities to increase productivity and manufacturing competitiveness, but it is difficult to convert to a smart factory due to insufficient investment. However, as ordering companies recently requested information such as production status and defect rate, SMEs are feeling the need to build a smart factory to secure reliability. Therefore, in this paper, aiming at CNC facilities, we designed and implemented a facility monitoring system using power data to support the establishment of smart factories of small and medium-sized enterprises (SMEs). The developed system uses time series data of power supplied to facilities collected from IoT sensor devices to detect abnormal changes in power required for the operation of production facilities, thereby revealing the relationship between abnormal changes in power and quality factors for each product in the future. By providing a power measurement that can be easily measured in almost any field, productivity can be improved.
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이덕행(Duk Heng Lee),이용주(Yong Joo Lee) 한국생약학회 1979 생약학회지 Vol.10 No.1
A trace amount of nicotine, main constituent in tobacco, contaminated in coffee, was identified by the T.L.C method. The Eastman chromagram plate was used and determined with the linear scanning by transmission method. It was possible to identify nicotine in coffee beverage regardless of types of tobacco. Ten micrograms of nicotine could be determined in a cup of coffee (75㎖), which was acidified with hydrochloric acid.
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