한방병원에 내원한 암환자 52명에 대한 NK cell Activity 특성 분석

이가영,김민지,정진용,유주영,조정효,손창규,이남헌,Lee, Ga-young,Kim, Min-ji,Joung, Jin-yong,Ryu, Ju-young,Cho, Jung-hyo,Son, Chang-gue,Lee, Nam-hun 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.4

Objectives: This study was aimed to analyze the correlation of clinical characteristics of cancer patients treated with Korean Medicine and their natural killer cell activity (NKA). Methods: The medical records of 52 cancer patients who conducted NKA test at Cheonan Korean Medicine Hospital of Daejeon University from March 2016 to May 2018 were reviewed. NKA was determined at Seegene Medical institute using NK Vue Gold(R) kit, evaluating activated $IFN-{\gamma}$ by enzyme immunoassay after incubation of whole blood. Careful investigations were conducted by categorizing the patients by their sex, origin, stage, ECOG scale, and conventional treatment type. We used data from the medical records and statistical analysis using SPSS 25.0 V. Results: The average NKA of all patients was $623.1{\pm}722.0pg/mL$. The NKA value was higher for females than for males. No correlation was evident between age and NKA, but patients aged over 70 years had the lowest NKA average result. Stage III and IV patients showed clearly lower NKA values when compared to stage I and II patients. NKA and ECOG scale values showed no evident relationship. Conclusions: This study presented the characteristics of NKA in cancer patients treated with Korean medicine. The NKA result differed by gender and stage. Based on these findings, further study is needed regarding the clinical meaning of NKA.

간찰 부위에서 발생한 전신형 고리 육아종 1예

허규 ( Gyoo Huh ),이현주 ( Heun-joo Lee ),최영준 ( Young-jun Choi ),김원석 ( Won-serk Kim ),이가영 ( Ga-young Lee ) 대한피부과학회 2021 大韓皮膚科學會誌 Vol.59 No.10

Granuloma annulare (GA) is a common non-infectious granulomatous disease. Generalized GA is the second most common variant of GA. It is often associated with recalcitrant disease progression despite treatment. The lesion of generalized GA typically presents widespread papules that coalesce to form annular plaques over the whole body. We report a case of a patient with disseminated papules and coalescing annular plaques, primarily involving the intertriginous area and mimicking tinea corporis or cruris. Histopathological findings confirmed the lesion as GA. This case underscored the unusual clinical presentation of generalized GA. A case of GA localized to the intertriginous area has rarely been reported. Given the recalcitrant nature of the disease, dermatologists should consider generalized GA as a differential diagnosis in patients with an annular lesion involving the intertriginous area. Thus, we report this as an atypical case of generalized GA localized to the intertriginous area. (Korean J Dermatol 2021;59(10):797∼800)

시니어 정보 사용성을 고려한 헬스케어 어플리케이션 UI Kit 디자인

이가영(Ga Young Lee),안성희(Sunghee Ahn) 한국HCI학회 2021 한국HCI학회 학술대회 Vol.2021 No.1

2020 년 기준 대한민국의 65 세 이상 노인 인구는 전체 인구의 15.7%로 고령사회로 진입하였으며 2030 년에는 25%, 2040 년에는 39.9%로 증가하여 초고령사회로 진입할 전망이다.[1] 그러나 환경적인 요인으로 디지털 사회로 급속한 진입은 디지털 기기에 익숙하지 않은 노인층을 디지털 소외층으로 밀어내는 문제를 안고 있다. 선행연구로 진행한 헬스케어 서비스 플로어차트에 기반하여 시니어의 인지 · 사회적 특성과 한계를 고려한 어플리케이션의 UX 디자인 프로세스 중 UI Kit 를 기획하였다. 일반 어플리케이션의 UX 디자인보다 서비스 경험 가운데 시각을 포함한 인지적인 문제가 크게 작용하는 바, 시니어를 위한 서비스의 사용자 경험에 대해 중점적으로 연구하였다.

천연물,유기합성 : 산수유 씨의 최종당화산물 생성저해활성 성분

이가영 ( Ga Young Lee ),장대식 ( Dae Sik Jang ),이윤미 ( Yun Mi Lee ),김영숙 ( Young Sook Kim ),김진숙 ( Jin Sook Kim ) 한국응용생명화학회 2008 Applied Biological Chemistry (Appl Biol Chem) Vol.51 No.4

사이버모델하우스 인터랙티브 디자인 실용성에 관한 연구

이가영 ( Lee Ga-young ),박윤성 ( Park Yoonsung ) 경기대학교 산업디자인연구소 2009 조형논총 Vol.6 No.-

VR(Vitual Reality) has a purpose on give an unusual environment experience as a real and could classify as information design. Recently, inspire of the Cyber Model House has been built from its facilities; unrestricted time, area, and expenses to construct companies and customers. As in all the model houses previously provide information of be being built house to customers. By the Cyber Model House, controlling the final shape of the buildings and options interactive, customers could have the substance of information what they want, maximize satisfaction and also could understand the descriptions easily. Such as VR system would adapted to not only the Cyber Model House but also the other industries parts and a e-commercial transaction bring up to basic model. It is hard to choose the primary process for the Cyber Model House which is in developing step. However, we could expect the trends from response of customers and various competition processes. Therefore, development process of Cyber Model House would depend on efficient information communication and experience process. In this research, extents analyzing general idea and tendency of information design, comprehend practical use and problems of the Cyber Model House, and to present advanced direction of the Cyber Model House interactive design.

대만해협과 심리전 ― 냉전시기 대만과 중국의 삐라를 중심으로 ―

이가영(Lee, Ga Young) 동북아시아문화학회 2021 동북아시아문화학회 국제학술대회 발표자료집 Vol.2021 No.10

This study analyzes the psychological warfare between China and Taiwan, focusing on the pira sprayed across the Taiwan Strait during the Cold War. As is well known, the second Taiwan Strait Crisis, which occurred under the banner of Taiwan"s "Reclam China" and China"s "Liberate Taiwan," is a artillery battle that fired large-scale shells at its opponents, and a psychological war in which various forms of acceleration broadcasts, propaganda broadcasts, and propaganda leaflets were distributed. The two sides carry out an omnidirectional psychological war to promote their ideology and ideas and induce the opponent"s loss and surrender of war. Among them, psychological warfare using propaganda leaflets has been recognized as a very effective psychological warfare method in that it could be exposed to many enemies. In addition, it was frequently used because it has excellent accessibility as a non-institutional medium that can deliver information to ordinary people who cannot access institutional media such as newspapers, magazines, radio, and broadcasting. The purpose of this article is largely divided into two. First, we look at various psychological warfare methods operated by China and Taiwan, and analyze psychological warfare using Pira among them. In particular, it analyzes the association of messages and images contained in beepers produced and distributed by China and Taiwan, and examines the mutual perception underlying them. Second, by deriving the prototypicity of the beepers of both sides and tracking the production purpose and operation logic of the beepers, we would like to understand the negative strategy and Propaganda Campaign of China and Taiwan.

심볼디자인의 상징적 의미화에 관한 시사점 고찰-역사적 사건에 의한 연상작용을 발생시키는 이미지를 중심으로-

이가영 ( Ga Young Lee ),문철 ( Chul Moon ) 한국기초조형학회 2014 기초조형학연구 Vol.15 No.6

상징적 심볼은 개인적 차원을 넘어 사회집단 안에서 큰 영향력을 지니게 된다. 이러한 영향력은 조직에 대한 자긍심, 애국심, 신뢰감과 같이 집단을 단결시키거나 어떤 브랜드에 대한 긍정적 이미지를 축척시키는 기능이 있다. 그러나 어떤 경우 상징적 심볼의 특정 이미지가 사람들에게 과거의 부정적인 경험을 연상시켜 전혀 의도하지 않았던 부정적인 반응을 일으키는 경우가 생기기도 한다. 예능프로그램에서 ‘욱일기’이미지 연상 의상 등을 통해 나타나고 있는 것이 대표적 사례이다. 본 연구에서는 이러한 현상의 특성과 원인을 유사사례를 통해 분석하였다. 심볼은 사용되는 시대의 요구에 따라 새로운 의미화 과정을 거쳐 본래 원형의 의미에서 많은 변화가 있을 수 있음 알수 있었다. 또한 강하게 인식되어진 이미지는 주변의 여러 디자인에서 조형적으로 유사하지 않더라도 연상작용을 불러 일으킬 만큼 사람들의 의식에 강하게 자리잡고 있었다. 이에 본 연구에서는 이미지가 각인된 심볼이라 할지라도 시대적으로 새로운 의미가 요구된다면, 문화적, 정서적으로 충분히 수용할 수 있는 의미화 과정이 필요하다고 보았다. 이를 위해 2차 세계대전의 전범기라는 논란이 되는 욱일기에 사용된 조형적 요소들을 가지고 있으나 의미화 과정을 통해 욱일기의 이미지 논란으로부터 비교적 거리가 있었던 심볼들을 예로 들어 재의미화와 설득의 과정을 살펴보았다. 그리고 눈으로 보여지는 조형성이 유사하더라도 역사적 인식을 고려하고 목적을 분명히 설정한다면 심볼의 새로운 의미화가 가능함을 알 수 있었다. 이러한 과정은 향후 디자인의 창의적 발전과 풍부한 의미를 부여하는데 큰 도움이 될 것으로 여겨진다 Emblematic Symbol has great influence with the social group, people, nations. The influence provides people with pride, patriotic spirit and formation of trust for national solidarity, oraccumulates the positive image of certain company brand. On the other hand, some image in the symbol brings up the image of negative experience which generates the negative emotion nothing to do with intention of producer. Recently, the similar cases have been shown in the entertainment media, where some entertainer costume brings up the image of ‘rising sun flag’ of militaristic nation. In this study, these cases were analyzed in the semiologic signification point of view. we found that there would be a lot of modifications from the original meanings by proper signifying process. Through this, when an image strongly recognized by events oreducations, it always exists in the human memory, which makes people remind the image on any circumstances with not similar image. So this study focused that If some symbol contains the image of negative meaning by historical events, it is suggested that signifying process would be necessary for creative design under the condition of cultural, emotional and historical capacity. For this, some images which are far from arousing a controversy by similarity of ‘risingsun’ were mentioned and analyzed based on the point of signifying process. Even the visual formativeness appears to be similar, new signification of symbol is possible once historialcognition is considered and objective is clarified. Through this, it is expected that creative development and affluent imagination show multiplier effect in our life.

Patch test

이가영 ( Ga-young Lee ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

l Patch testing-recommended cases 1) Etiological diagnosis of allergic contact dermatitis (ACD) and allergic contact dermatitis syndrome (ACDS) : Algorithmic approach of problems is an efficient way to reach a good evaluation in terms of diagnosis and managements of ACD. Patch testing has a key role in this algorithmic approach. 2) Differential diagnosis of ACD versus irritant contact dermatitis (ICD) 3) Eczematous conditions considered endogeneous (eg. atopic dermatitis, nummular dermatitis, seborrheic dermatitis, asteatotic dermatitis, stasis dermatitis, eczematous lesions around leg ulcers, pompholyx, lichenification, and hyperkeratotic eczema on palm and sole). : Its results permit further avoidance of contact allergens in the management of eczematous conditions. l Patch test procedure 1) The allergens are mixed with a non-allergic material (petrolatum, alcohol, water) to a suitable concentration. 2) They are then placed in direct contact with the skin within Finn Chamber^{^®}. - The substances incorporated in a semisolid base are applied directly into the chamber. - For liquid, a filter-paper disk is placed in the chamber and saturated with the liquid. 3) Finn Chambers should be applied to the back starting with the lower part and pressing the chambers from below to let the air escape. - Preferred site is upper back. False-negative reaction can be obtained when testing on the lower back or volar forearms. 4) Patches should be left under occlusion for 48 hours. l Allergens in patch test 1) Screening patch test series include standard series, cosmetic series, fragrance series, rubber series, dental series and T.R.U.E test^® etc. T.R.U.E test^® is a commercially available patch-test screening tool with US Food and Drug Administration (FDA) approval. 2) The T.R.U.E. test^® allergens were incorporated into a hydrophilic gel that is dried into a thin film. When applied to skin, this film becomes hydrated by skin moisture and the allergen is released. 3) As is series - Patients` own cosmetics (lotion, cream, and makeup foundation) can be tested without dilution - Patients` cleansing agents (soap, shampoo, etc.) should be diluted with water into appropriate concentration. 5) The open or provocative use test is administered before closed patch testing, if no safe concentration for closed patch testing is known. 6) No unidentified chemical should be tested, and no chemical from an occupational source should be tested without due diligence and attention to appropriate testing concentration for dilution. l Patch test reading 1) Traditionally, patch-test reading is carried out twice: the day of patch-test removal 48 hours application, and 96 hours after epicutaneous exposure. - If allergies to metals, topical antibiotics (neomycin), and PPD are strongly suspected, additional readings at 5-7 days may be needed. 2) Interpretation - Positive results in both reading times mean `contact allergen` 3) Criterion for patch test results l Patch test with medication 1) Topical steroid should be avoided for at least a week prior to testing, and systemic steroid should not be used at least a month prior to testing. 2) Patient who need systemic steroid for other comorbilities should take prednisone under 20mg per day. Repeating patch testing after treatment discontinuation can be useful when in doubt. 3) Antihistamines such as diphenhydramine are permissible prior to and during testing. But, in most clinics, antihistamine treatment is discontinued during testing. 4) A recent study has concluded that patch test reactions can be elicited in patients taking azathioprine, cyclosporine, infliximab, etanercept, MTX, mycophenolate mofetil and tacrolimus. However, it remains unclear what effect these immunosuppessive drugs may have on suppressing allergic patch test reaction

시니어 디지털 리터러시를 반영한 천식 관리 앱 서비스 분석

이가영(Ga Young Lee),최해진(Hae Jin Choi),신광수(Kwang Soo Shin),안성희(Sunghee Ahn) 한국디자인학회 2020 한국디자인학회 학술발표대회 논문집 Vol.2020 No.6

작금의 사회적 환경은 디지털 디바이스를 통한 온라인 소통채널의 활용이 급격히 확산되는 추세와 인터넷 서비스의 진화로 개인화에 대한 니즈에 힘입어 우리의 생활 속에서 여러 건강과 관련된 서비스들을 온라인화 시키는데 일조하고 있다. 의료 서비스에 있어서도 원격진료에 대한 필요성이 더욱 대두되고 있는데. 특히 만성적인 질환들의 경우는 일상 속에서 꾸준한 관리를 요하기 때문에 케어 매니지먼트 앱으로서의 의료서비스의 확장성을 보여 준다. 의료나 건강관리 등에 관한 앱은 그동안 꾸준히 확산되어 왔으나 시니어 연령대를 대상으로 한 앱의 개발에 관련된 연구는 아직 많지 않다. 본 연구는 이러한 시대적 니즈를 반영하여 시니어들을 대상으로 한 만성질환인 천식과 호흡기 앱(App)을 개발하고자 하는 목적을 가지고 이를 위한 기초연구로서 기존의 국내외적으로 출시된 앱의 사용성 분석과 전문가 인터뷰 등을 통해 필수적인(기본적인) 서비스 항목을 추출하는 과정을 UX(User experience) 디자인 리서치 연구 방법론을 통해 진행 하였다. 최종 결과로는 천식 케어 앱을 위한 서비스 항목 등을 추출하였고 이를 기반으로 앱 플러어차트를 설계하였다. 또한 전문가 인터뷰를 통해 수정보완 하였다.

공공디자인의 국제개발협력을 위한 발전방안 연구 -KOICA의 도시개발 협력 사례를 중심으로-

이가영 ( Lee Ga Young ) 한국기초조형학회 2018 기초조형학연구 Vol.19 No.2

본 연구에서는 국제개발협력에 있어서 국제기구에서 정한 SDGs의 목표인 건강하고 질 좋은 삶과 안정적으로 유지되는 도시와 커뮤니티에 기여할 수 있는 분야로서 공공 디자인을 정하였다. 그 이유는 공공 디자인이 적용되는 모든 영역이 언어, 국가, 민족, 종교 및 습관 등의 차이에 관계없이 누구나 쉽고 편안하게 모든 생활과 산업 분야에서 접근성이 용이한 특성이 있으므로 이를 국제 개발협력의 관점에서 바라보면 수원국 지역공동체의 공공질서, 치안, 위생과 관련하여 삶의 질을 높이는 데 충분히 기여할 수 있을 것으로 판단되기 때문이다. 기존 연구결과에 따르면 도시의 공공성에 기여하는 디자인은 삶의 질을 개선하는 데 큰 역할을 하고 있는 것으로 나타나고 있으며 개발도상국에도 마찬가지로 삶의 질을 개선하는데 중요한 역할을 할 수 있을 것으로 여겨지므로 개도국의 관점에서 필요한 공공디자인 요소가 무엇인지 분석해 보았다. 이를 위해 국제개발협력 사례를 바탕으로 우리나라의 공적원조에 있어서 디자인 분야는 어떻게 반영이 되고 추진되었는지를 분석하였고, 좀 더 범위를 넓혀서 공공디자인과 연관된 영역으로 볼 수 있는 도시개발, 도로교통 개선 등과 관련된 개발협력 사업 추진 시 공공디자인에 대해 어떠한 요소가 고려되었는지 살펴보았다. 이를 바탕으로 향후 공공 분야의 개선과 관련된 국제개발협력 추진 시 고려해야 할 사항을 요소별로 도출하여 향후 공공디자인의 발전방향을 제시하였다. In this study, public design was defined as a field that can contribute to the healthy and high quality life and stable cities and communities that are the goal of SDGs defined by international organizations in international development cooperation. The reason for this is that all areas where public design is applied are easily accessible to all living and industrial sectors regardless of differences in language, country, ethnicity, religion and customs. It is believed that this will contribute to improving the quality of life in relation to public order, security, and hygiene of local communities in the country. According to the results of previous research, design contributing to the publicness of the city has been shown to play a major role in improving the quality of life, and it is thought that developing countries can also play an important role in improving the quality of life. I analyzed what public design elements are needed. For this, we analyzed how the design field was reflected and promoted in Korea's public aid, and it is related to the urban development and road traffic improvement We looked at what elements were considered for public design when developing cooperation projects. Based on this, the factors to be considered in the promotion of international development cooperation related to the improvement of the public sector will be elucidated.