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      • KCI등재
      • KCI우수등재

        흰쥐에 사염화탄소 투여가 혈청 Acid Phosphatase활성에 미치는 영향

        윤종국,신중규,차상은 한국환경보건학회 1991 한국환경보건학회지 Vol.17 No.2

        To clarify a cause of increased serum level of acid phosphatase in CCl$_{4}$-treated rats, the acid phosphatase activity of liver was compared with that serum. Concomitantly, the serum and liver acid phosphatase activity of CCl$_{4}$-treated rats were compared with that of CCl$_{4}$-treated rats pretreated with prednisolone or actinomycin D. In CCl$_{4}$-treated rats, the activity of serum acid phosphatase was significiantly increased whereas that of liver acid phosphatase was rather slightly decreased. the pretreatment of prednisolone led to the decreased activity of serum and liver acid phosphatase in CCl$_{4}$-treated rats. But the pretreatment of actinomycin D rather increased the activity of liver and serum enzyme. In conclusion, it is likely the increased activity of serum acid phosphatase is based on the excess leaking of acid phosphatase into blood by the increased membrane permeability of both liver cell and lysosome in it.

      • KCI등재

        철강용접자의 크롬 및 망간 노출평가와 산업위생관리 대책에 관한 연구

        윤종국,이영세,박종안,이송권,채종홍,김억수 한국산업위생학회 2000 한국산업보건학회지 Vol.10 No.1

        Results of environmental monitoring for 35 steel industry welders exposed to manganese and chromium fume were evaluated. Efficiency of respiratory protectors, welding face shields and local exhaust ventilation were also evaluated to establish more efficient preventive measures that can protect welders from occupational disease as related to welding fume. The results are as follows; 1. Total fume from CO₂ arc welding with mild steel occurred 1.5 to 2.2 times more than that from shielded meta arc welding. Chromium and nickel fume from welding with stainless steel occurred 27 to 59 times and 18 to 30 times, respectively, than those with mild steel. 2. Proportions of water-soluble chromium(VI) and insoluble chromium(VI) Compare to total chromium occurring from CC₂ arc welding with stainless steel were 10.5% and 8.7%, respectively, while those with mild steel were 57.1 to 63.2% and 31.6 to 38.1%, respectively. 3. The efficiencies of 4 types of respiratory protectors to reduce welding fume exposure were evaluated as 54.4 to 64.4%. 4. The reducing effect of head type welding face shield was 67.6%, and that of hand type welding face shield was 58.5%. The highest reducing effect was shown in air supply welding face shield as 99.2%, although it is not convenient to wear. 5. When welding face shield and respiratory protectors were worn together, the reducing efficiency increased to 79.0 to 87.5%. 6. When local exhaust ventilation was installed in workplace, the reducing efficiencies varied from 31.5 to 73.1% according to the types of welding.

      • 코울리지 시에 나타난 분리와 재창조의 시적 과정

        윤종국 서강영문학회 1990 서강영문학 Vol.2 No.-

        이 논문의 목적은 분리와 재 창조의 형태로 발생하는 상상력으로 상이한 반대요소를 결합시키는 코울리지의 시적 과정을 연구하는 것이다. 코울리지의 시중 「한 밤중에 내린 서리」("Frost at Midnight"),「낙담:송가」("Dejection: an Ode")와 「크리스타벨」("Christabel") 세편에 나타난 시적 과정을 추적해 보고자 한다. 코울리지의 분리 및 재 창조의 시적 과정은 그의 유명한 평론집인 『바이오그라피아 리테라리아』에 잘 정의되어 있다. 상상력의 통합하는 힘을 지각되는 요소를 분해함으로써 인지의 기본 행동을 반복하는 것이며 동 요소들을 “재 창조”하는 것을 목적으로 하며 “상반된 요소를 재 결합”하는 형태로 나타난다.

      • SCOPUSKCI등재

        흰쥐에 toluene 투여가 백혈구 xanthine oxidase 및 superoxide dismutase 활성에 미치는 영향

        윤종국,이혜자,최미애 한국독성학회 1995 Toxicological Research Vol.11 No.2

        This study was designed to observe the effect of tohiene pretreatment on leukocyte variation in whole blood and the oxygen free radical generating, scavenging enzyme activities in neutrophil of bacteria infected rats. Toluene was administered 7 times intraperitoneally at levels of 9.45 mM/kg body weight to the rats and then infected with S. aureus $2\times10^7$ cfu/ml. The toluene treated-rats showed the significantly decreased numbers of lymphocyte and monocytes, but the similiar numbers of neutrophils with the control. Furthermore the increased neutrophils in blood of bacteria infected rats were reduced by the toluene pretreatment. Concomitantly the increased activities of xanthine oxidase and superoxide dismutase in neutrophil of bacteria infected rats were also decreased by the toluene pretreatment. On the other hand, injection of benzaldehyde to rats also led to similiar results in the count of leukocytes, xanthine oxidase and superoxide dismutase activities of neutrophil with those of toluene treated rats. These data suggest that toluene and its intermediate metabolite, benzaldehyde influence on the phagocytosis and defence mechanism of neutrophil.

      • SCOPUSKCI등재

        유기 금속 화학 증착법에 의한 $(Ba_{1-x},\;Sr_x)TiO_3$ 박막의 제조 및 전기적 특성

        윤종국,윤순길,Yun, Jong-Guk,Yun, Sun-Gil 한국재료학회 1995 한국재료학회지 Vol.5 No.7

        저압 유기금속 화학 증탁법에 의하여 Pt/Ti/SiO$_2$/Si 기판위에 (Ba$_{1-x}$ , Sr$_{x}$)TiO/$_3$박막이 제조 되었다. 제조된 BST 박막의 결정화도는 증착온도가 증가함에 따라 (100)방향으로 우선 성장하였다. 90$0^{\circ}C$에서 증착한 BST 박막은 100kHz의 주파수에서 유전상수가 365, 유전손실이 0.052를 나타내었다. 인가전계에 따라 축전용량의 변화가 작은 상유전 특성을 보였으며 0.2MV/cm인가 전계에서 축적 전하 밀도(charge storage density)는 60fC/$\mu\textrm{m}$$^2$을, 0.15MV/cm인가 전계 영역에서 누설 전류밀도(leakage current density)는 20nA/$\textrm{cm}^2$을 나타냈다.냈다. (Ba$_{1-x}$ , Sr$_{x}$)TiO/$_3$thin films on Pt/Ti/SiO$_2$/Si substrates were prepared by LP MOCVD(Low Pressure Metal-Organic Chemical Vapor Deposition). The crystalinity of BST deposit had a (100) preferred orientation with increasing deposition temperature due to surface diffusion. BST films deposited at 90$0^{\circ}C$ showed a dielectric constant of 365 and a dissipation factor of 0.052 at a frequency of 100kHz. The chance of capacitance of the films with applied voltage was small, showing paraelectric properties. BST film deposited at 90$0^{\circ}C$ had a charge storage density of 60 fc/${\mu}{\textrm}{m}$$^2$at a field of 0.2MV/cm and the leakage current density of 20 nA/$\textrm{cm}^2$ at a field of 0.15 MV/cm.cm.

      • KCI등재

        On the Geometry of Charged Rotating Black Holes

        윤종국 한국수학사학회 2022 Journal for history of mathematics Vol.35 No.2

        In this paper, we review some aspects of geometry for charged rotating black holes which are formed from the gravitational collapse of a massive spinning star with electric charge. We also introduce the computation of entropy for black holes from loop quantum gravity which is a quantum theory of gravity based on Einstein's theory of general relativity.

      • SCOPUSKCI등재

        흰쥐에 있어서 주정중독이 Toluene 대사에 미치는 영향

        윤종국,윤선동,신중규 한국독성학회 1996 Toxicological Research Vol.12 No.2

        To evaluate an effect of ethanol pretreatment on the toluene metabolism, toluene (50% in olive oil) was given three times at 0.2 ml/100g body weight at the interval of one day to the rats fed with 5% ethanol during two months. The ethanol pretreated rats were not identified particular liver injury by the histopathologic findings. In case of toluene treatment, the ethanol pretreatment to the rats led to more increased concentration of urinary hippuric acid than those treated with only toluene. The ethanol pretreatment to the rats led to the increased activities of hepatic aniline hydroxylase and these enzyme activities were higher both in toluene treated and those pretreated with ethanol, but no differences were found in two groups. Ethanol pretreated rats showed the more increased activities of benzylalcohol dehydrogenase than control group. Moreover, the ethanol pretreatment to the toluene treated rats led to significantly more increased activities of benzylalcohol dehydrogenase compared with those treated with toluene only. Furthermore, the alcohol pretreatment to the toluene treated rats also led to somewhat higher activities of benzaldehyde dehydrogenase than those treated with toluene. In conclusion, these results indicate that the chronic pretreatment of ethanol at not so much liver damage as normal may rather activate the toluene metabolism.

      • Mouse小腸 Xanthine Oxidase의 性質

        尹鍾國 啓明大學校 生活科學硏究所 1979 科學論集 Vol.5 No.-

        mouse小腸을 酵素材料로 하여 xanthine oxidase의 성질을 관찰하여 다음과 같은 몇가지 結果을 얻었다. 小腸에 存在하는 xanthine oxidase는 dehydrogenase형은 測定할 수 없었다. 部分精製한 本酵素의 活性은 pH 8.0부근에서 가장 높았다. Xanthine을 基質로 하였을 때 本酵素의 ??은 ??M이었다. Allopurinol은 本酵素에 對하여 경쟁적인 抑制를 보였으며 ??値는 ??M이었다. Only a few reports have been appeared on the comparatively higher activity of xanthine oxidase in mouse small intestine than that in other tissues. For the reason, the properties of xanthine oxidase in mouse small intestine was studied in order to more clarify the nature of the enzyme. The results are as follows; 1. The activity of xanthine oxidase in mouse small intestine revealed the enzyme to be type O but not type D. 2. The optimal pH was near to 8.0 for xanthine oxidase in partially purified mouse small intestine. 3. The ?? value for xanthine for xanthine oxidase activity with xanthine as a substrate was calculated to be ??M. 4. Allopurinol did act as a competitive inhibitor on the xanthine oxidase activity with xanthine as a substrate, and the ?? value was calculated to be ??M.

      • KCI등재후보

        로렌츠변환의 선형성에 대한 고찰

        윤종국 제주대학교 교육과학연구소 2018 교육과학연구 Vol.20 No.2

        In 1905, Einstein has derived the Lorentz transformation which is the coordinate change between different inertial frames using the two postulates, that is, relativity principle and the invariance of speed of light. This transformation has completely changed the notion of space and time of Newton and has been proved by the accurate experiments. Einstein assumed that this important transformation, which contains the essential features of special relativity, should be linear from the homogeneity of space and time. But many arguments about the logical implication of this assumption has followed. Many disputes and attempts like this have an important meaning in view of the completeness of the proof and some pedagogical reasons and they help us make a deeper understanding of the mathematical structure of special relativity. In this paper, using the two postulates we provide a new method of derivation of the linearity of the Lorentz transformation without assuming the continuity or differentiability and prove the Lorentz transformation. 1905년에 아인슈타인은 특수상대성이론을 발표하여 상대성의 원리와 광속도 불변의 원리라는 2가지 핵심가설을 바탕으로 서로 다른 두 관성계 사이의 시공간 좌표변환식인 로렌츠 변환식을 유도하였다. 이 로렌츠 변환식은 기존의 뉴턴역학의 시간과 공간의 개념을 완전히 바꾸어 놓았으며 정밀한 실험을 통해 실제로 확인되어왔다. 이처럼 특수상대성이론의 핵심적인 내용을 담고 있는 중요한 변환식이라 할 수 있는 로렌츠 변환식을 유도하는 과정에서 아인슈타인은 공간과 시간의 균질성을 근거로 이 변환식이 선형변환임을 가정하였다. 그러나 이러한 가정의 논리적 필연성에 대해 보다 엄밀한 정당화를 요구하는 많은 논의가 뒤따랐다. 증명의 엄밀성을 위해서 뿐만이 아니라 교육학적 측면에서도 중요한 의미를 갖는 이와 같은 다양한 논의와 시도는 우리로 하여금 로렌츠 변환식과 특수상대성이론의 수학적 구조에 대한 보다 깊은 이해를 할 수 있도록 도와주고 있다. 본 논문에서는 로렌츠변환식의 연속성이나 미분가능성의 가정 없이 위 두 가설만을 전제로 한 간단하고 기본적인 방법으로 이 변환의 선형성을 유도하는 과정을 새롭게 제시하고 이를 통해 로렌츠 변환을 다시 유도해 보고자 한다.

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