벤처기업 경영자 특성이 경영성과에 미치는 영향에 관한 연구;대덕연구개발특구를 중심으로

윤보현,박준병,Yoon, Bo-Hyun,Park, Joon-Byoung 한국벤처창업학회 2007 벤처창업연구 Vol.2 No.3

Current researches have been proceed on CEO's Characteristics of venture business because the CEO has considered as one of the important factors for the success of venture business. But prior research on the performance of venture business has produced inconsistently in terms of CEO's characteristics. The purpose of this study is to develop a comprehensive model for the relation between the performance and a type of CEO's characteristics by a growth process of venture business, which is the main subject of analysis in venture business. Also, this study analyzes various CEO's characteristics and the effects for performance of venture business which are in the Daedeok valley. To achieve the purpose of this research, an empirical study by using research model and hypotheses including the general characteristics of venture business and CEO's demographic characteristics has been presented as a research method for relation analysis. The principal findings of the research and its significance are summarized as follows: First, it was found that there is a significant different in the performance of CEO's behavioral characteristics by the scale, type and growing step of organization for venture business. Second, it was found that there is not a significant between an academic career, management experience, foundation experience for business and related working experience of venture CEO and the performance, but there os a partially significant difference in CEO's behavioral characteristics. Third, it was found that there is a partially significant difference between CEO's behavioral characteristics of venture business and the performance by the general characteristics of organization for venture business and demographic characteristics. In conclusion, in spite of the insufficient research for venture business in Daedeok, the implications of theses findings and contributions made by this research is to confirm the characteristics factor of CEO for venture business and general characteristics of organization for venture business by multidisciplinary side. In addition, the findings provide the basis for the analyzing of managerial strong point and weak point referred to supporting system for venture business. Finally, the findings of this study suggest that the results should be a useful data for groping a solution for upbringing plans in terms of a long-term point of view.

정상성인에서 ALDH-I의 변이가 알콜의 정신운동성 수행과 주관적 평가에 미치는 영향

윤보현,윤진상,Yoon, Bo Hyun,Yoon, Jin Sang 대한생물정신의학회 1996 생물정신의학 Vol.3 No.2

The purpose of this study was to evaluate the effects of alcohol on the psychomotor performance and subjective assessment in healthy Korean adults with acetaldehyde dehydrogenase I(ALDH-I) isozyme variance. A total of 20 male subjects, half with active ALDH-I and the other half with inactive ALDH-I, were selected through both a self-reporting questionnaire examining alcohol sensitivity and the Higuchi's ethanol patch test detecting ALDH-I deficiency. In a doule-blind, placebo-controlled cross-over design, each subject consumed four doses of alcohol(0.25, 0.5, 0.75, 1.0g/kg) and placebo on five separate occasions at weekly intervals, Treatment order was fully balanced using a $5{\times}5$ Latin square, Psychomotor performance tests[coritical flicker fusion threshold(CFF) and choice reaction time(CRT)] and self-estimate questionnaires were conducted at baseline and at time points of 20, 40, 60, 90, 120, 150, 180 minutes after consuming the test drug for 20 minutes, Blood alcohol concentrations(BACs) using breath analyzer were measured at baseline and at time points of 10, 20, 30, 40, 50, 60, 75, 90, 105, 120, 150, 180 minutes after drinking, The BACs and the mean changes in the psychomotor performances and subjective assessments from pre-alcohol baseline, were compared between the two groups. The findings were summarized as follows : 1) BACs were tended to be higher in the inactive group than the active in all of the four alcohol doses. However significant group differences were only after the 0.5g/kg dose of alcohol. 2) The inactive group showed significant impairment in CFFT at most time points alter 0.75 and 1.0g/kg doses of alcohol. 3) In CRT, total reaction time(TRT) significantly prolonged in the inactive group than the active group at 20 minutes after 0.25 and 1.0g/kg doses of alcohol and at 40, 60, 90 minutes alter 0.75g/kg dose of alcohol. In the inactive group, recognition time component significantly increased at 20, 60, 90 minutes after 1.0g/kg dose of alcohol, while movement time component significantly increased at 40, 60 minutes after 0.75g/kg dose of alcohol. 4) Subjective evaluation of the effect of alcohol revealed that physical and mental conditions as well as a self-estimate of the effects of alcohol on performance were significantly worse in the inactive group than the active at some time points alter all of the lour alcohol doses, wihch were more pronounced after 0.75 and 1.0g/kg doses of alcohol. 5) Most of the group differences mentioned above, still remained statistically significant after BAC was entered as a covariate, These findings demonstrated that the alcohol sensitivity is higher in individuals with inactive ALDH-I than those with active ALDH-I both on the subjective assessments and the objective psychomotor performances. Furthermore, these results suggest thai the alcohol sensitivity may be determined by acetaldehyde concentration rather than BAC per se. In future studies, after more accurate genotyping for ALDH-I, the relationships between BAC, acetaldehyde concentration and alcohol sensitivities should be clearly defined. ALDH-I 활성군과 비활성군에서 음주후 정신운동성 수행 및 주관적 평가에 미치는 영향을 비교하였다. 사교적 음주에 상응하는 4종류의 알콜(0.25, 0.5, 0.75, 1.0g/kg)을 투여한 결과 비활성군이 활성군에 비해 보다 부정적인 평가를 하였다. 이는 특히 고용량의 알콜(0.75 및 1.0g/kg)을 투여시 분명하였다. 이러한 결과는 비활성군이 활성군에 비해 알콜에 대한 민감성이 주관적인 판단과 객관적인 수행에서 모두 더 높다는 사실을 반영한다.

호흡음주측정에서 Alco-Sensor Ⅳ와 Lion Alcolmeter SD-400P의 비교

윤보현(Bo-Hyun Yoon),정명섭(Myung-Sub Jung),표경식(Kyung-Sik Pyo),임채식(Chae-Sig Lim),이병회(Byung-Hoi Lee),박용현(Yong-Hyun Park) 한국중독정신의학회 1999 중독정신의학 Vol.3 No.1

Objectives:The aim of this study was to evaluate the interreliabilities and reproducibilities of two breathanalyzers which commonly used in clinical settings, research fields, and legal purposes including roadside testing. Methods:Thirty-four healthy male volunteers were examined through 30, 60, 90, 120, 150 and 180 minutes after 20 minutes’ intake of one of the two doses of alcohol (0.5 and 0.75 g/kg of body weight) on separate occasions. Two kinds of breathanalyzers [Alco- Sensor Ⅳ (Intoximeters, Inc., USA;Alco-Sensor) and Lion Alcolmeter SD-400P (Lion Laboratories plc, UK;SD-400P)] were used to measure the breath alcohol concentrations (BrAC). Duplicate breath samples at each time point were used to determine the repeatabilities of the breathanalyzers. Results:Mean values of two breathanalyzers at each time point were not statistically different. Although there were not significant, the values obtained from SD-400P were tended to slightly higher than those of Alco-Sensor. Inter-reliabilities of Alco-Sensor and SD-400P at 0.5 and 0.75 g/kg of body weight were very high[r=0.972 (p〈.001);r= 0.938 (p〈.001), respectively]. Test-retest reliabilities of Alco-Sensor and SD- 400P were also very high[r=0.976 (p〈.001); r=0.984 (p〈.001), respectively]. Conclusion:The two breathanalyzers can be used as highly reliable instruments in all kinds of fields including roadside testing. Although further studies concerning the accuracy and precision of the breath-alcohol measurements in Koreans should be done, it suggests that these instruments may be easily and safely used as evidential breath testing.

정상 성인에서 ALDH2 유전형에 따른 알코올 민감성, 음주행태 및 알코올 효과에 대한 기대의 비교

윤보현(Bo-Hyun Yoon),윤진상(Jin-Sang Yoon),최태석(Tae-Suk Choi),송제헌(Je-Heon Song) 한국중독정신의학회 1999 중독정신의학 Vol.3 No.2

To investigate the interrelations of ALDH2 genotype (biological factor) and alcohol expectancy (psychosocial factor) as the predictors of alcohol use and alcohol-related problems, we compared the alcohol sensitivity, alcohol habits and alcohol expectancy in normal adults with ALDH2 variations. A total of 20 healthy male subjects (the half with ALDH2*1/*1, the other with ALDH2*1/*2) was selected through screening tests and genotyping by amplification created restriction site. The questionnaires for alcohol sensitivity, drinking history and habits, and the modified version of Alcohol Expectancy Questionnaire (AEQ) were administered to the subjects. Data were compared between two groups of ALDH2 genotype. ALDH2*1/*2 subjects reported more negative physiological responses than ALDH2*1/*1 subjects. ALDH2*1/*1 subjects had more frequent histories of alcohol-induced blackouts and consumed more alcohol in terms of frequency and quantity than ALDH2 *1/*2 subjects. ALDH2*1/*1 group showed significantly high scores on negative expectancy, socializing expectancy and tension reduction expectancy scales among 5 subsets of AEQ. This study suggests that the ALDH2 genotype not only clearly affect the alcohol-induced biological responses, but also have the effects on psychosocial dimensions that are related with alcohol use and abuse.

각종 과배란유도방법에 따른 난포액내의 Prolactin농도의 동태 및 체외수정의 성공과의 관련성에 관한 연구

윤보현(BH Yoon),장윤석(YS Chang) 대한산부인과학회 1987 Obstetrics & Gynecology Science Vol.30 No.12

1985년 4월부터 12월까지 서울대학교 부속병원 산부인과 시험관애기 프로그램에 등록이 되어 시술을 받은 환자 26명으로부터 성숙된 배란직전의 난자가 채취된 48개의 난포액을 대상으로 본 연구를 시행하였다. A군 5명은 clomiphene citrate로, B군 5명은 clomiphene citrate와 hMG를 병용하여, C군 7명은 hMG로, D군 9명은 FSH와 hMG를 병용하여 과배란유도를 시행하였다. 채취된 난포액의 PRL의 농도를 측정하여 각각의 과배란유도 방법에 따른 농도의 차이를 확인하고, 체외수정을 시도하여 난포액내의 PRL의 농도와 체외수정 및 임신의 성공과의 관련성을 비교하여 다음과 같은 결과를 얻었다. 1. Clomiphene citrate를 사용한 A군 및 B군의 난포액내의 PRL농도는 각각 20.4±7.7ng/ml, 24.7±3.6ng/ml로 clomiphene citrate를 사용하지 않은 C군 및 D군의 44.2±6.3ng/ml, 41.9±3.4ng/ml에 비하여 통계적으로 유의하게 낮은 농도를 보였다. 그러나 A군과 B군사이, C군과 D군사이에는 유의한 농도차리를 확인할 수 없었다. 2. Clomphene군(A군 및 B군), Non-clomiphene군(C군 및 D군) 모두에게 체외수정이 확인된 난자가 채취된 난포액의 PRL농도가 체외수정에 실패한 경우와 비교하여 유의한 차이가 없었다. 3. 임신된 환자는 Non-clomiphene군에만 4명이 있었다. Non-clomiphene군에서 수정이 되어 배아이식 후에 임신이 성립된 환자의 난포액의 PRL 농도가 임신이 되지 않은 경우와 비교하여 유의한 차이가 없었다. Prolactin(PRL) has pronounced effects on ovarian physiology in vivo. Women with hyperprolactinemia have amenorrhea and infertility with poor follicular growth. Our recent study has shown that clomiphene citrate appears to have an inhibitory effect on the rise of PRL in response to increasing serum estradiol levels during hyperstimulated menstrual cycle. Ovarian hyperstimulation was carried out in 33 women with clomphene citrate(n=5), clomiphene citrate/hMG(n=5), hMG(n=7) and FSH/hMG(n=9), and follicular aspiration was performed 36h after hCG administration. PRL concentrations in follicular fluid(FF) of 48 follicles from which preovulatory oocytes were obtained were correlated with the various hyperstimulation methods, the success of fertilization in vitro and pregnancy after embryo transfer. PRL concentrations in FF from patients hyperstimulated by clomiphene citrate(20.4±7.7ng/ml), clomiphene citrate/hMG(24.7± 3.6ng/ml) were significantly lower than those by hMG(44.2±6.3ng/ml), FSH/hMG(41.9± 3.4ng/ml)(P<0.05). There was no correlation between FF concentrations of PRL and successful fertilization of human ova in vitro, and the success of pregnancy after embryo transfer. In conclusion, FF PRL concentration was decreased when clomiphene was used as hyperstimulation agent. And it seemed that FF PRL concentration did not play a pivotal role in the success of in vitro fertilization and pregnancy after embryo transfer.

만삭전 조기양막파수 산모에서 양수내 백혈구수 측정의 진단 및 예후적 가치

윤보현(Bo Hyun Yoon),김미하(Mi Ha Kim) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.1

Objective : The aim of this study was 1) to determine the diagnostic performance of amniotic fluid white blood cell (WBC) count for the antenatal detection of intrauterine infection and 2) to identify the value in prediction of preterm birth and significant neonatal morbidity in patients with preterm premature rupture of membranes. Methods : Transabdominal amniocentesis was done in 255 singleton pregnancies with preterm premature rupture of membranes before 36 weeks of gestational age. Amniotic fluid was cultured for aerobic and anaerobic bacteria and mycoplasmas. Receiver-operator characteristic curve, survival analysis and logistic regression were used for statistical analysis. Results : 1) Prevalence of positive amniotic fluid culture was 19.6% (50/255). Amniotic fluid WBC count was higher in the patients with positive amniotic fluid culture than those with negative amniotic fluid culture (median 269 [0-19764] cells/mm3 vs median 2 [0-7956] cells/mm3, p<0.001). 2) As a diagnostic and prognostic means, the increased amniotic fluid WBC (≥20 cells/mm3) had sensitivity of 74%, specificity of 74%, positive predictive value of 41% and negative predictive value of 92% for the positive result of amniotic fluid culture. 3) An increased amiotic fluid WBC was strongly associated with shorter amniocentesis-to-delivery interval even after adjustment of gestational age at amniocentesis(hazard ratio 3.2736, p<0.0001). 4) Amniotic fluid WBC count was higher in patients with significant neonatal morbidity or congenital neonatal infectious morbidity than those without these (p<0.001 and p<0.005 respectively). 5) Patients with increased amniotic fluid WBC count had higher incidence of significant neonatal morbidity and congenital neonatal infectious morbidity than those with low amniotic fluid WBC count and the association between amniotic fluid WBC and significant neonatal morbidity was statistically significant after adjustment of gestational age at amniocentesis (OR 3.3649, p<0.0001). Conclusion : Amniotic fluid WBC count is of value in antenatal diagnosis of intrauterine infection and prediction of maternal and neonatal outcomes in patients with preterm premature rupture of membranes.

여행운송업에서의 사회적 책임의 효과

윤보현(Yoon, Bohyun),문준호(Moon, Joonho),강윤식(Kang, Yunsik) 한국관광레저학회 2018 관광레저연구 Vol.30 No.9

국내 주식시장의 대안 인덱스 연구 : 스마트 베타를 중심으로

윤보현 ( Bohyun Yoon ),손경우 ( Kyoung-woo Sohn ),유원석 ( Won-suk Liu ) 한국파생상품학회(구 한국선물학회) 2017 선물연구 Vol.25 No.2

본 연구는 전통적 인덱스 투자전략의 대안으로써 스마트 베타전략의 유의성을 살펴 보고자 하였다. 이를 위해 이미 알려진 이례현상(anomaly) 종목을 대상으로, 다양한 비중 결정방법에 따라 최적화된 포트폴리오들의 성과를 측정, 비교, 분석하였다. 본 연구가 발견한 주요 결과는 다음과 같다. 첫째, 시가총액비중 이외의 비중으로 최적화된 포트폴리오는 효율성을 제고할 수 있는 것으로 나타났다. 둘째, 다양한 방법으로 최적화된 포트폴리오는 효율성의 제고를 가져오지만, 시장전체 종목을 대상으로 구성되는 한 이상(abonormal) 초과수익률 알파의 창출은 어려운 것으로 나타났다. 반면, 이례현상 종목만을 대상으로 최적화된 포트폴리오는 효율성 제고뿐 아니라 유의한 초과수익률 알파의 창출이 가능한 것으로 나타났다. 셋째, 이례현상 종목 대상 최적화된 포트폴리오의 성과는 공매도 제한상황에서도 유의하였다. 이러한 결과들은 자산운용업계에 중요한 함의를 제공한다. 첫째, 펀드매니저는 스마트 베타전략 포트폴리오를 벤치마크로 패시브운용하여 마켓 타이밍 등 액티브 전략 없이 트래킹만으로도 유의한 알파를 창출할 수 있다. 둘째, 펀드 매니저는 전망 및 예측과 관련된 비용 및 전망 및 예측오류에 의한 위험을 감소시킴으로써 효율성을 제고할 수 있다. Recently, due to its passive property, the smart beta has become one of the most interest topics in searching the alpha. In this paper, we attempt to show whether the smart beta strategy generate abnormal excess return, in tradition, which are known as the exclusive property of active fund. Further, we attempt to verify the key drivers of the alpha in the smart beta portfolios. For this purpose, we categorize various smart beta strategies by their scheme for asset picking and risk reduction. Then, based on our categorization, we evaluate and analyze the performance of smart beta strategy in perspective. Our empirical analyses show following results: applying alternative risk reduction scheme to traditional market index portfolio would results in enhanced efficiency; however, without combining any asset picking scheme, the performance of the smart beta portfolio seems explained by the Fama-French 3 factor. Our results lead us to conjecture that it is not the portfolio weighting scheme alone but in association with asset selection scheme that generate significant alpha in the smart beta strategy. In actual practice, our results imply that any passive fund may succeed in seeking the alpha without active strategy, thereby avoiding the risk of market timing and saving the management cost.

한국 주식시장에서의 대안 인덱스투자전략 연구

윤보현 ( Bo Hyun Yoon ),최영민 ( Young Min Choi ) 한국파생상품학회(구 한국선물학회) 2014 선물연구 Vol.22 No.2

본 연구는 주식시장의 시가총액 비중 시장 인덱스의 위험 대비 수익률 관점의 비효율을 지적하며 등장한 다양한 대안적인 인덱스 투자전략을 한국 주식시장에 적용하여 실증 분석한다. 대안 인덱스 투자전략이란 인덱스를 구성하는 종목의 비중 계산을 시가총액 비중이 아닌 재무제표를 이용하거나, 평균-분산 최적화 결과를 이용하는 등의 방법을 이용하는 것으로 한국 주식시장에서 포트폴리오를 구성하여 수익률을 측정한 결과, 시장 인덱스보다 위험 대비 수익률의 효율성이 증대함을 확인하였다. 또한 대안인덱스의 초과수익률은 Fama-French의 3요인 분석 결과 시장요인 및 기업규모요인 그리고 가치요인의 세 가지 요인으로 설명이 가능한 것으로 나타났다. 하지만, 이 사실이 대안 인덱스의 유용성을 해친다고 할 수는 없다. Fama-French의 기업규모요인이나 가치요인은 매수/매도 포지션으로 이루어져있고, 포트폴리오 재구성 시 높은 수준의 시장충격이 발생할 가능성이 높기 때문이다. 본 연구는 이러한 측면에서 대안 인덱스가 100% 매수 포지션으로만 이루어져 있고 회전율도 높지 않기 때문에 기업규모요인이나 가치요인을 실질적으로 투자가능하게 만들어주는 순기능이 존재할 수 있음을 제시하였다. There have been several studies of alternative equity index strategies which suggest better investment opportunities with higher risk adjusted return pointing out empirical evidence of inefficient risk-return trade-off implied in the market-cap weighted index. Commercial products based on these strategies, regarded as passive equity strategies, become more popular in the U.S. and European stock markets. We investigates whether these strategies are also valid in Korean stock market and our empirical results add support to their efficacy. From Fama-French 3-factor analysis, we find that the excess return of alternative equity index is attributed to market, size and value factors and it does not show a significantly positive alpha. Even without positive alpha, however, these strategies are valuable to investors in the sense that they offer opportunities to fully exploit size and value premium with long-only portfolios. The advantage of these strategies is more straightforward recalling the fact that rebalancing of Fama-French factor portfolios involves short-sale and high turnover.

발육지연태아를 분만한 임산부의 산전 자궁동맥 혈류속도파형의 양상

윤보현 ( Bo Hyun Yoon ),강영제 ( Yeong Je Kang ),이필량 ( Pyl Ryang Lee ),송현진 ( Hyun Jin Song ),신희철 ( Hee Chul Syn ),김승욱 ( Syng Wook Kim ) 대한주산의학회 1991 Perinatology Vol.2 No.2