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임신 중기 양수천자 1,565 례에 대한 세포유전학적 분석 : CUMC 경험 (1)
안현영(Hyun Young Ahn),정대영(Dae Young Jung),백은정(Eun Jung Baik),이형근(Hyung Geun Lee),문희봉(Hee Bong Moon),이지현(Jee Hyun Lee),김석찬(Seok Chan Kim),신종철(Jong Chul Shin),나종구(Jong Goo Rha),김수평(Soo Pyung Kim) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.6
Objectives: To analyze chromosomal abnormalities according to patients age and indications of patients in midtrimester amniocentesis for prenatal genetic diagnosis. Methods: We retrospectively analyzed 1,565 cases of midtrimester prenatal genetic amniocentesis cases which were done in the cytogenetics laboratory at Kangnam St. Hospital, Catholic University Medical College from November1997 to May 2000. Results: In 1,565 cases, the most common maternal and gestational age distributions were 35 to 39 years old and 17 to 17+6 weeks (32.78Vo and 2l.47%, respectively). Abnormal maternal serum markers were the most common indication for amniocentesis (43.64%), and followed by advanced maternal age (40.45%) and abnormal ultrasonographic findings (3.64%). The overall incidence of chromosomal abnormalities was 4.47% (70 cases), of which numerical abnormalities and structural abnormalities were 1.86% (29 cases) and 2.61% (41 cases), respectively. Among the autosomal abnormalities, Down syndrome was most common (10 cases, 0.65%), and followed by Edward syndrome (9 cases, 0.59%). Among the sex chromosomal abnormalities, both of 47,XXX and 47,XXY were most common (3 cases, 0.20%, respectively). Chromosomal abnormalities were most frequently noted in the maternal age of 25 to 29 years old (5.10%), 30 to 34 years old (4.82%), 40 to 44 years old (4.31%), and followed by 35 to 39 years old (3.90%). On the other hand, chromosomal abnormalities were most frequently noted in abnormal ultrasonographic findings (7.02%), previous history of aneuploidy (5.88%), and followed by advanced maternal age (3.95%). Conclusion: This study suggested that although advanced maternal age is still important indication in midtrimester amniocentesis for prenatal diagnosis, abnormal maternal serum markers and ultrasonographic findings might be also important as indications. Therefore, they should be considered in prenatal genetic counseling.
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주요우울장애 환자에서의 심박변이도와 혈중 지질 농도와의 연관성
안은정,최진숙,장용이,이해우,심현보,Ahn, Eun-Jung,Choi, Jin-Sook,Jang, Yong-Lee,Lee, Hae-Woo,Sim, Hyun-Bo 대한수면의학회 2012 수면·정신생리 Vol.19 No.1
목 적 : HRV 검사는 교감 신경과 부교감 신경의 억제 체제에 의해 조절되는 심박변이도를 측정하고 분석하는 도구로서, 현재 민감하고 비침습적인 도구로 인정받고 있다. 우울증 환자들은 불안, 우울과 같은 정신적 스트레스를 지속적으로 받으면서 자율신경계 억제 기전의 교란을 받게 된다. 우울증은 또 심혈관 질환의 이환과 사망률을 예측하는 독립적 예측인자라고 보고되고 있다. 본 연구에서는 HRV 검사를 통하여 정상인과 우울증 환자 사이에서 HRV와 lipid level 사이의 상관관계를 알아보려고 하였다. 방 법 : 2011년 7월부터 2012년 3월까지 서울의료원 정신건강의학과 우울증 클리닉에 내원한 외래 및 입원 환자 중, 만 19세 이상 65세 이하 환자(42명)를 대상으로 하였고, 환자들과 나이, 성별을 일치시킨 병원에서 근무하는 직원 중 정신과 과거력과 신체 질환이 없는 사람(32명)을 대상으로, HRV, 혈중 지질 농도, HAM-A(hamilton anxiety scale), HAM-D(hamilton depression scale)를 조사하였다. 우울증 환자군과 정상대조군을 독립표본 t-검정 및 카이제곱-검정을 시행하여 비교하였다. Pearson 상관 분석을 이용하여 우울 증상의 심각도, HRV 세부지표, 혈중 지질 농도 간의 상관관계를 살펴보았다(p<0.05). 결 과 : 우울증 환자군과 정상대조군 사이에 인구학적 변인은 차이가 없었으며, 우울증 환자군에게서 HAM-D & HAM-A 점수가 높았다. 혈중 지질 농도 검사에서, 우울증 환자군이 정상군보다 cholesterol, TG, LDL 수치가 유의하게 높게 측정되었다. HRV 시간영역 분석(time domain analyses)에서, 우울증 환자군이 정상군보다 SDNN이 낮게 나왔으나 유의한 차이는 보이지 않았다. 한편, ApEn(approximate entrophy)이 정상군보다 우울증 환자군에서 유의하게 높았으며, ApEn은 LDL, HAM-D, HAM-A와 유의한 상관관계를 보였다. 결 론 : 우울증 환자군의 HRV에서 ApEn이 정상대조군보다 높게 측정되었다. ApEn은 최근에 개발된 비선형적 분석으로 HRV 신호가 얼마나 복잡한 지를 통계적으로 정량화한 수치이며, 데이터 양이 적고, 잡음이 많은 생리학적 데이터를 분석하기에 적합하다고 알려져 있다. 본 연구에서는 ApEn이 우울증 환자군에서 유의하게 높게 나왔으며, ApEn이 LDL, HAM-D, HAM-A와도 상관관계를 갖는 것으로 나타났다. 향후, HRV를 임상적 상황에서 실용적으로 사용하는 연구에 있어, ApEn을 새로운 평가 도구로서 주목할 필요가 있겠다. Objectives: The analysis of heart rate variability (HRV) is a useful non-invasive tool to investigate the autonomic nerve function. Previous studies on the relationship between HRV and depression have been reported controversial results. Similarly, the correlation between the serum lipids and depression is debatable. The purpose of this study is to examine the relationship between heart rate variability, lipid profile and depression. Methods: A total of 42 patients with major depressive disorder (MDD) and 32 age and sex-matched normal subjects who had no previous history of major medical and mental illnesses were recruited for this study. A structured-interview was used to assess the general characteristics and psychiatric illness. HRV measures were assessed by time-domain and frequency-domain analyses. Psychological symptoms were measured using the Hamilton rating scale for anxiety (HAM-A), Hamilton rating scale for depression (HAM-D). In addition, the evaluation for lipid profile was performed by blood test. Results: In serum lipid profile test, MDD group showed higher cholesterol ($197.68{\pm}42.94$ mg/dL vs. $176.85{\pm}34.68$ mg/dL, p=0.044), TG ($139.45{\pm}92.54$ mg/dL vs. $91.4{\pm}65.68$ mg/dL, p=0.018), LDL ($130.03{\pm}33.18$ vs. $106.62{\pm}27.08$, p=0.004) level than normal control group. In HRV time domain analyses, the standard deviation of the NN interval (SDNN) was decreased in MDD group than normal control group, but was not significant ($32.82{\pm}14.33$ ms vs. $40.36{\pm}21.40$ms, p=0.078). ApEn (Approximate Entrophy) was significantly increased in MDD group than normal control group ($1.13{\pm}0.11$ vs. $0.91{\pm}0.18$, p<0.001). ApEn was correlated with LDL level (r=0.277, p=0.028), HAM-D scores (r=0.534, p<0.001) and HAM-A scores (r=0.470, p<0.001). Conclusions: MDD patients showed increased ApEn, one of the HRV measurement. And this ApEn was correlated with LDL, HAM-D and HAM-A scores. In this study, the analysis of ApEn would be a useful test of MDD.
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전시주최자 운영능력에 따른 참가업체의 전시회 만족도에 관한 연구: 2008 국제자동화정밀기기전을 중심으로
안은정 ( Eun Jung Ahn ),황희곤 ( Hee Kon Hwang ) (사)한국마이스관광학회(구 한국컨벤션학회) 2009 MICE관광연구 Vol.9 No.2
Though trade show have emerged as an increasingly significant component in companies` international tools, little research has examined this activity and previous findings on this theme are few and mostly foreign. This research studies the relationship between organizer`s operation and exhibitors` satisfaction about trade show. This study aims to analyze the exhibitors` satisfaction about trade show and organizer`s operation so that organizer can set up effective strategies for planning, marketing and operation. Results are as follows: 1. High satisfaction with organizer`s operation correlate with exhibitors` satisfaction about trade show significantly. 2. High satisfaction with organizer`s marketing ability correlate with exhibitors` satisfaction about trade show significantly. This results suggest that organizer should make an effort in order to enhance trade show performance. Also suggest efficient management of trade show may increase it`s performance.
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안은정(Eun Jung Ahn) K교육연구학회 2023 사회과학리뷰 Vol.8 No.4
본 연구는 어린이집 교사의 권리침해 경험에 대해 알아보고 그에 따른 대안을 종합적으로 탐색해보고자 하였다. 연구 대상자는 현장경력 최소 5년 이상의 어린이집 교사 3인을 대상으로 각각 총3회씩 매회 1시간30분 이상 총 9회 심층면담을 진행하였다. 면담내용은 녹음 후 전사하는 과정을 거쳐 Bogdan & Biklien(1992)가 제시한 방법에 따라 반복읽기를 통해 특정단어, 어휘, 사고방식, 사건 등을 중심으로 맥락화와 범주화 및 의미를 도출하여 분석하였다. 연구시작 전 반구조화된 질문지를 개발하여 면담을 실시하였고 질문목록은 사전에 유아교육과 교수2인과 현장전문가인 육아종합지원센터장 3인을 대상으로 문항내용을 수정, 보완하여 반구조화된 질문목록을 구성하였다. 연구결과로는 어린이집 보육교사의 권리침해 경험으로는 내 아이를 위한 요구와 거침없는 표현이 가능한 부모와 반박할 권리를 허용받지 못하는 교사로 나타났으며, 어린이집 보육교사의 교권 회복을 위한 대안으로는 어린이집 교사라는 자긍심, 다양한 방법을 통한 신뢰쌓기, 아이들을 위한 제도를 바르게 이해하기로 제시하였다. The purpose of this study was to investigate the rights infringement experiences of daycare center teachers and to comprehensively explore alternatives. The subjects of this study conducted a total of 9 in-depth interviews with 3 daycare center teachers with at least 5 years of field experience, 3 times each for at least 1 hour and 30 minutes. The interview contents were transcribed after recording, and then contextualized, categorized, and analyzed by repeated reading according to the method suggested by .Bogdan & Biklien (1992). Before the start of the study, a semi-structured questionnaire was developed and interviewed, and a semi-structured question list was constructed by revising and supplementing the contents of the questions in advance for two professors of the Department of Early Childhood Education and three heads of the Comprehensive Childcare Support Center, who are field experts. As a result of the study, it was found that the experience of violating the rights of daycare center teachers was a parent who was not allowed to demand for and express their children without hesitation and the right to refute, and it was suggested that as an alternative to restoring the teaching rights of daycare center teachers, the pride of being a daycare center teacher, building trust through various methods, and understanding the system for children correctly.
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안은정(Ahn Eun-Jung),이영숙(Lee Young-Sook) 대한종양간호학회 2005 Asian Oncology Nursing Vol.5 No.1
The purpose of this study was to explore the relationship between burden and burnout of the family care-givers for caring of terminal patients with cancer. A total of 99 convenience sample was recruited form hospitals. The data were collected by a direct interview with Questionnaire about family burden and burnout. The mean score of burnout of main care-givers was 2.98, and the mean score of burden was 3.03. The care-givers' burnout was significantly different by age, sex, job, duration of treatment, level of acceptance on the stage of death, and ability of daily living activities. The family care-givers' burden was significantly different by the jobs, complication of patients, level of acceptance on the stage of death, and ability of daily living activities. In conclusions, the burnout of family care-givers was highly and positively correlated with the burden.
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