도금액 관리에 관한 조사연구

신종철(Jong Chul SHIN),박광자(Kwang Ja PARK),이성주(Sung Joo LEE),이종용(Jong Yong LEE) 한국표면공학회 1977 한국표면공학회지 Vol.10 No.1

지표면 영향을 고려한 삼각 전파 반사기의 RCS 분석

신종철(Jong-Chul Shin),권순구(Soon-Koo Kweon),오이석(Yisok Oh),김세영(Se-Young Kim),전병태(Byeong-Tae Jeon) 한국전자파학회 2012 한국전자파학회논문지 Vol.23 No.6

위성 SAR(Synthetic Aperture Radar)를 정확하게 보정하기 위해서는 검보정에 사용되는 삼각 전파 반사기(Trihedral Corner Reflector: TCR)의 RCS(Radar Cross Section)를 정확하게 계산해야 한다. 본 연구에서는 TCR이 설치된 지표면이 TCR의 RCS 값에 얼마나 영향을 미치는지를 알아보기 위해서 지표면에서의 반사파와 TCR 모서리에서의 회절파를 이론적으로 계산하여 검보정 사이트의 지표면 상태에 따른 RCS 변화를 분석하였다. 지표면 반사파를 구하기 위해 지표면에 대한 PO 반사 계수를 이용하였으며, PO 반사 계수는 지표면 상태 변수인 거칠기와 유전율에 대한 함수이다. 중심 주파수 9.65 ㎓에서 지표면 위에 설치된 10 λ 크기 TCR의 RCS 값은 공기중의 TCR에 비해 0.46 ㏈ 변화가 발생하였고, 이 변화는 지표면의 상태 및 TCR 크기에 따라 크게는 1.55 ㏈ 정도의 차이가 날 수 있다. 지표면 영향에 따른 TCR의 RCS 값은 지표면의 거칠기가 작고 유전율이 클수록 크며, 중심 주파수가 낮고 TCR의 크기가 작을수록 크게 발생하였다. The radar cross section(RCS) of a trihedral corner reflector(TCR) should be accurately computed when it is used as an external calibration target for a satellite synthetic aperture radar(SAR) calibration campaign. This paper presents the RCS analysis on a trihedral corner reflector which is installed on a calibration site, using the wave reflection from the rough surface and the wave diffraction from the TCR edges. The results in this paper show quantitatively the effect of the front surface on the RCS of a TCR. The difference of the RCS between a TCR in air and a TCR on a ground surface is computed by including the interaction term which consists of the edge diffraction from the TCR edges and the surface reflection from the front rough surface. The reflection coefficient of a randomly rough surface is a function of the surface roughness and dielectric constant of the surface. The RCS of 10 λ size TCR on a ground is 0.46 ㏈ higher than TCR in air at 9.65 ㎓, and this can reach at maximum 1.55 ㏈ depending on a surface condition and TCR size. The effect of the front surface on the RCS of a TCR increases, as the surface roughness decreases, the soil moisture increases, and the size of TCR in wavelength decreases.

인간태반에서 혈관내피성장인자 및 태반성장인자의 유전자 발현

신종철(Jong Chul Shin),이영(Young Lee),정대영(Dae Young Chung),백은정(Eun Jeong Baik),오민정(Min Jung Oh),양동은(Dong Eun Yang),김사진(Sa Jin Kim),김창이(Chang Ee Kim),김수평(Soo Pyung Kim) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.8

목적: 정상임신 및 비정상임신의 태반에서 혈관내피성장인자 및 태반성장인자의 유전자 발현유무 및 정도를 비교분석하기 위하여 시행하였다. 연구방법: 각 삼분기의 정상임신과 계류유산, 자궁내 태아발육지연 및 전자간증의 태반조직을 이용하여 총 RNA를 추출하였다. cDNA를 합성한 후 VEGF 및 PlGF primer를 사용하여 RT-PCR을 시행하였다. 결과: 정상임신과 계류유산의 모든 예에서 VEGF121, VEGF165 , VEGF189 등과 PlGF131, PlGF152 등이 확인되었으며, VEGF 및 PlGF 모두 임신주수에 따른 유전자 발현정도는 뚜렸한 차이를 보이지 않았다. 자궁내 태아발육지연에서는 4예 중 2예에서 4개의 VEGF 아형( VEGF121, VEGF145, VEGF165, VEGF189)이 모두 관찰되었다. 전간증에서는 3예 중 1예에서 5개의 VEGF아형이 모두 관찰되었다. 그러나 VEGF121, VEGF165, VEGF189 등과 PlGF131, PlGF152 등의 발현정도는 정상임신과 뚜렸한 차이를 보이지 않았다. 결론: VEGF 및 PlGF는 태반에서 발현될 뿐 아니라 VEGF의 경우는 자궁내 태아발육지연 및 중증 전자간증의 일부 예에서는 발현정도가 증폭되었다. 이러한 결과들은 VEGF가 정상임신 태반의 신생혈관생성에 관여하고 특히, 태아의 저산소증 상태에서는 VEGF의 생성이 증가할 가능성이 있음을 보여주고 있다. Objective : To determine whether gene expressions of VEGF and PlGF are different between the human placenta of normal and abnormal pregnancy. Methods : Placenta was collected at each trimester of normal pregnancy, missed abortion, intrauterine growth retardation and pre-eclampsia. Total RNA was extracted from placenta. Reverse transcription-polymerase chain reaction(RT-PCR) was performed using VEGF and PlGF primer. Results : VEGF121, VEGF165 and VEGF189 were identified in normal pregnancy and missed abortion. In two cases of four IUGR and one case of three pre-eclampsia, four of isoforms (VEGF121, VEGF145, VEGF165, and VEGF189) were identified. The intensity of signal was strongest for VEGF165 in all cases. PlGF131 and PlGF152 were identified in all cases. However, the signal intensities of VEGF121, VEGF165, VEGF189, PlGF131 and PlGF152 were not different according to the gestational age. They were also not different between normal pregnancy and abnormal pregnancy. Conclusion : VEGF and PlGF were not only expressed at placenta but also overexpressed in part of IUGR and pre-eclampsia. The results suggest that VEGF may play a role in the induction of angiogenesis of placenta in normal pregnancy and its production may be increased under the hypoxic condition.

반응성 염료의 색도 제거를 위한 균주 분리 및 최적화

신종철(Jong Chul Shin),최광근(Kwang Keun Choi),전현희(Hyun Hee Jeon),김상용(Sang Young Kim),이진원(Jinwon Lee) 한국생물공학회 2004 KSBB Journal Vol.19 No.3

간세포 성장인자가 HT 세포주에서 matrix metalloproteinase 의 발현에 미치는 영향

신종철(Jong Chul Shin),문희봉(Hee Bong Moon),이지현(Jee Hyun Lee),양동은(Dong Eun Yang),이귀세라(Gui Se Ra Lee),이영(Young Lee),이종승(Jong Seong Lee),김창이(Chang Yi Kim),김수평(Soo Pyung Kim) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.12

N/A Objective : This study was performed to investigate the influence of hepatocyte growth factor (HGF) on matrix metalloproteinase (MMP), which are related in the lysis process of tissue during the invasion of trophoblasts. Method : HT cell line was treated with recombinant HGF (rHGF) of different concentration (0, 10, 50 and 100 ng/mL) and was cultured for 24 hours to check the changes in the expression of MMP-2 and MMP-9. Also, HT cell line was treated with recombinant HGF 50 ng/mL and was cultured for 24, 36, 48, and 72 hours to check the changes in the expression of MMPs according to the different time span. Total RNA were extracted from each cultured sample and RT-PCR and Western blotting were used to analyze the expression of MMP-2 and MMP-9. Results : MMP-2 mRNA expression with treated rHGF showed increase of 2, 2.5 and 2.2 times with the increase of concentration level of 10, 50 and 100 ng/mL accordingly, while MMP-2 protein expression were increased 1.4 and 1.5 times in 50 ng/mL and 100 ng/mL of rHGF respectively compared with that of normal control. MMP-9 mRNA showed no significant changes in its expression with all different levels of concentration, while MMP-9 protein showed 1.5 times increase with 10 ng/mL rHGF but 0.4 times decrease with 100 ng/mL. MMP-2 mRNA expression treated with recombinat HGF were increased 1.6 times with 24 hour culture and 2.3 times with 36 hour culture. MMP-2 protein showed 1.9 times increase only for the case of 24 hour culture. MMP-9 mRNA expression of recombinant HGF-treated groups was decreased 0.7 times compared with that of control group in 36 hours. MMP-9 protein expression were increased by 1.2, 1.6 and 1.9 times as culture time increase to 36, 48, and 72 hours accordingly, compared with that of normal control. Conclusion : This result suggests that the HGF might partially regulate the invasion of trophoblasts through MMP-2 and MMP-9.

태아가사의 감소에 있어서 산과의사의 역할

신종철 ( Jong Chul Shin ) 대한주산의학회 2003 Perinatology Vol.14 No.4

간세포 성장인자가 HT 세포주에서 c - met 의 발현과 침투성에 미치는 영향

신종철(Jong Chul Shin),이지현(Jee Hyun Lee),양동은(Dong Eun Yang),오민정(Min Jeong Oh),문희봉(Hee Bong Moon),이영(Young Lee),김사진(Sa Jin Kim),이종승(Chong Seung Yi),김수평(Soo Pyung Kim) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.8

N/A Objective : To evaluate the invasive capacity of trophoblastic cells when treated with HGF, and see whether HGF induces c-met expression in vitro. Methods : HT cell line was treated with recombinant HGF (rHGF) at different concentrations (0, 10, 50 and 100 ng/mL) and cultured for 24 hours. To evaluate according different time of culture, HT cell line was pre-treated with 50 ng/mL rHGF and cultured for 24, 36, 48 and 72 hours. We analyzed the expression of c-met mRNA using reverse transcriptase-polymerase chain reaction and the expression of c-met protein using western blot in each samples. We also observed cellular invasion capacity through the invasion assay under a microscope and confirmed 72 kDa gelatinase and 92 kDa gelatinase expression patterns by zymography assay. Results : The expressions of c-met mRNA and protein were increased in all concentrations of rHGF, compared with that of normal control although it was not in dose-dependent fashion. In invasion assay, the number of invaded HT cells were increased in dose-dependent fashion, compared with that of normal control. In zymography ssay, the expression of 72 kDa gelatinase was increased in dose-dependent fashion, compared with the control. However, 92 kDa eglatinase was not detected in any studied group. Conclusion : These results suggests that HGF might be related to upregulation of trophoblast cell invasiveness by activation of c-met and subsequent induction of 72 kDa gelatinase.

모체로부터 태아세포의 발견 및 산전유전진단에의 이용

신종철 ( Jong Chul Shin ) 대한주산의학회 2000 Perinatology Vol.11 No.1

3차원 초음파와 MRI를 이용하여 진단한 배꼽탈장을 동반한 흉제대쌍둥이

윤종숙 ( Jong Sook Yoon ),박미선 ( Mi Sun Park ),김민정 ( Min Jeong Kim ),이귀세라 ( Gui Se Ra Lee ),박인양 ( In Yang Park ),임현욱 ( Hyun Wook Lim ),신종철 ( Jong Chul Shin ),김사진 ( Sa Jin Kim ) 대한산부인과학회 2007 Obstetrics & Gynecology Science Vol.50 No.12

One of the most interesting congenital malformations is a conjoined twin. Conjoined twins are a rare occurrence in obstetric practice. More commonly known as Siamese twins, this phenomenon is shrouded in mystery and considered a curiosity by general public. Current technology is providing a basis for earlier diagnosis and a better prognosis. Frequently, the twins are born dead, but there are a few cases in which the twins survive. We present a case of thoraco-omphalophagus with omphalocele in 35 years old woman at 25weeks 5 days gestation by 3-D ultrasonography and MRI.

다중 주사 경로 회로 기판을 위한 내장된 자체 테스트 기법의 연구

김현진,신종철,임용태,강성호,Kim, Hyun-Jin,Shin, Jong-Chul,Yim, Yong-Tae,Kang, Sung-Ho 대한전자공학회 1999 電子工學會論文誌, C Vol.c36 No.2

The IEEE standard 1149.1, which was proposed to increase the observability and the controllability in I/O pins, makes it possible the board level testing. In the boundary-scan environments, many shift operations are required due to their serial nature. This increases the test application time and the test application costs. To reduce the test application time, the method based on the parallel opereational multiple scan paths was proposed, but this requires the additional I/O pins and the internal wires. Moreover, it is difficult to make the designs in conformity to the IEEE standard 1149.1 since the standard does not support the parallel operation of data shifts on the scan paths. In this paper, the multiple scan path access algorithm which controls two scan paths simultaneously with one test bus is proposed. Based on the new algorithm, the new algorithm, the new board level BIST architecture which has a relatively small area overhead is developed. The new BIST architecture can reduce the test application time since it can shift the test patterns and the test responses of two scan paths at a time. In addition, it can reduce the costs for the test pattern generation and the test response analysis. 인쇄 회로 보드 수준의 테스팅을 위해 제안된 IEEE 표준 1149.1은 보드상의 테스트 지점에 대한 제어용이도와 관측용이도를 향상시켜 보드의 테스트를 용이하게 해준다. 그러나, 경계 주사 환경에서는 테스트 입력과 테스트 결과에 따른 데이터가 하나의 주사 연결에 의해서 직렬로 이동된다. 이는 테스트 적용시간을 증가시키고 따라서 테스트에 드는 비용을 증가시킨다. 테스트에 소모되는 시간을 줄이기 위해 병렬로 다중주사 경로를 구성하는 방법이 제안되었다. 하지만 이는 여분의 입출력 핀과 내선을 필요로 한다. 더구나 IEEE 표준 1149.1은 주사 경로 상에 있는 IC들의 병렬 동작을 지원하지 않기 때문에 표준에 맞게 설계하기가 어렵다. 본 논문에서는 하나의 테스트 버스로 두 개의 주사 경로를 동시에 제안하는 다중 주사 경로 접근 알고리즘에 기초하여 적은 면적 오버헤드를 가지고 빠른 시간 내에 보드를 테스트할 수 있는 새로운 보드수준의 내장된 자체 테스트 구조를 구현하였다. 제안된 내장된 자체 테스트 구조는 두 개의 주사 경로에 대한 테스트 입력과 테스트 결과를 이동시킬 수 있으므로 테스트에 소모되는 시간을 줄일 수 있고 또한 테스트 입력의 생성과 테스트 결과의 분석에 소모되는 비용을 줄일 수 있다.