익상편 발생기전에서 말초혈액의 내피전구세포 및 혈관신생인자의 관여

송영수,이정규,김재찬.Young Soo Song. M.D.. Jeong Kyu Lee. M.D.. Jae Chan Kim. M.D.. Ph.D. 대한안과학회 2006 대한안과학회지 Vol.47 No.9

Purpose: We investigated whether endothelial progenitor cells (EPCs) and vasculogenic factors are involved in the pathogenesis of pterygium and the mechanism underlying the selective recruitment of EPCs during this process. Methods: We studied 13 normal controls and 28 pterygium patients [ primary (n=15), recurrent (n=13)]. Substance-P, vascular endothelial growth factor (VEGF), and stem cell factor (SCF) were measured in plasma and tears using ELISA, and circulating CD34+ and c-kit+ mononuclear cells (MNCs) by flow cytometry. Anterior segment fluorescein angiography (FAG) was performed to evaluate hypoxic conditions in the early stage of pterygium. Surgically removed pterygial tissues were analyzed immunohistochemically using the progenitor cell markers, CD34, c-kit, VEGFR-1 and VEGFR-2. Results: Anterior segment FAG findings showed an increase in non-perfusion areas and attenuated vessels in the nasal limbus during early stage pterygium. Circulating CD34+ MNCs and c-kit+ MNCs were increased in pterygium groups compared with normal controls. Systemic and local cytokines including SP, VEGF and SCF in pterygium groups were also elevated and showed positive correlations with CD34+ and c-kit+ MNC numbers. Immunohistochemical analysis of pterygium showed strong progenitor cell marker immunoreactivities. Conclusions: EPCs might be involved in pterygium development, and ocular hypoxia triggers this neovascualrization by recruiting EPCs derived from the bone marrow via the production of systemic and local cytokines.

그레이브스병 환자에게서 항갑상선제 투여 후 발생한 무과립구증 1 예 및 10 년 간의 증례 고찰

송영수(Young Soo Song),강신명(Shin Myung Kang),안철우(Churl Woo Ahn),차봉수(Bong Soo Cha),장항석(Hang Suk Chang),정웅윤(Wung Youn Chung),송영득(Young Duk Song),임승길(Seung Kil Lim),김경래(Kyung Rae Kim),이현철(Hyun Chul Lee),박정수( 대한내과학회 2001 대한내과학회지 Vol.60 No.4

Since introduce of antithyroid drugs (ATDs) in 1941, they have been widely used for treatment of Graves' disease and other hyperthyroid disorders. However, agranulocytosis, the most serious adverse effect of ATD treatment, has been occasionally reported. Agranulocytosis should be diagnosed and be treated promptly due to possible fatality. We have experienced a 17 year-old girl with PTU (propylthiouracil)- induced agranulocytosis. Initial graulocyte count was 400/㎣, and presenting symtoms were fever and sore throat . She has recovered from agranulocytosis without complications after use of G-CSF (granulocyte-colony stimulating fact or). We reviewed and analyzed additional 7 cases of ATD-induced agranulocytosis in Yonsei University Hospital (From 1988 to 1998). We found that ATD-induced agranulocytosis, of which incidence is known to be ranged from 0.1 to 1 percent , does not seem to have a distinct correlation with sex, age, dosage, and the kind of ATD. Event of agranulocytosis has a tendency to occur within 3 months, and in a few case it has been occasionally detected in asymptomatic patients, routine monitoring of the white blood cell count within 3 months after the start of ATD medication can be helpful in predicting and in detecting agranulocytosis. The treatment of ATD-induced agranulocytosis has been mainly composed of conservative care, but according t o introduction and popular application of G- CSF, the use of G-CSF seems to be a promise of a reduction in morbidity and mortality.(Korean J Med 60:398- 403, 2001)

CIPP 평가모형을 적용한 경력사원 입문교육 프로그램의 만족도에 영향을 미치는 요인분석

송영수(Young-Soo Song) 중앙대학교 한국인적자원개발전략연구소 2011 역량개발학습연구 Vol.6 No.4

본 연구는 경력사원 입문교육의 학습환경 구성요인에 대한 참여자의 인식수준과 만족도에 영향을 주는 요인을 분석하여 경력사원 입문교육의 설계 및 운영에 시사점을 제공하는 것을 목적으로 한다. 이를 위하여 CIPP 평가모형을 적용한 연구도구를 개발하였고, 국내 H기업의 경력사원 119명을 대상으로 설문을 실시하였다. 이들이 입문교육에 대하여 느끼는 인식수준과 만족도를 분석한 결과는 다음과 같다. 첫째, 경력사원 입문교육의 학습환경 구성요인 중 학습자의 인식수준이 가장 높은 항목은 '교육환경', '교육활동', '기업 만족도 및 입문교육 필요 수준', '기업이해', '교육안내', '기업의 인재육성 시스템 지원 수준', '조직적응'으로 나타났다. 둘째, 경력사원 입문교육 만족도에 가장 큰 영향을 미치는 요인으로는 '교육활동', '조직적응', '기업이해' 순으로 나타났다. 즉, 교육환경적인 요소에 대한 인식수준이 높기는 하지만 실질적으로 학습자들이 기대하는 교육성과를 달성하고, 과정상에서 학습자의 특성을 고려한 다양한 교수법과 교육전략을 적용하여 진행하는 교육활동이 이들의 만족도에 상대적으로 큰 영향을 미치는 것으로 나타났다. 본 연구는 경력사원 입문교육의 전반적인 운영현황을 경력사원을 중심으로 분석하여 입문교육과정의 운영과 설계에 있어 우선적으로 고려해야 할 요인을 체계적으로 제시하는데 그 의의가 있다. The purpose of this study is to provide implications on design and administration of entrance training for the experienced employees by analyzing their recognition level about components in entrance training context and the factors which primarily influence their satisfaction on entrance training. CIPP (Context-Input-Process-Product) evaluation model was applied to develop the study method and the subject of this study were 119 experienced employees in H corporation. The results are as follow. First, the critical components affecting experienced employees' recognition in their entrance training, rated from highest to lowest, were 'training environment', 'training activity', 'satisfaction of corporation and learners' training needs', 'understanding of corporation', 'introduction of entrance training', 'corporational support of human resource cultivation', and 'adoption to organization'. Second, the factors that have significant effect on experienced employees' satisfaction of entrance training were 'training activity', 'adoption to organization', and 'understanding of corporation'. This result shows that the level of learners' recognition about components in entrance training context is high but more importantly, that the educational activities applied various learner-centered teaching methods and strategies play considerable role in learners' satisfaction in entrance training. The result of this study is expected to contribute to suggesting the priority factors to design and manage entrance training for the experienced employees.

다단계 특징벡터 기반의 분류기 모델

송영수(Young Soo Song),박동철(Dong Chul Park) 대한전자공학회 2009 電子工學會論文誌-CI (Computer and Information) Vol.46 No.1

본 논문은 다단계 특징벡터를 이용한 분류기 모델(Multistage Feature-based Classiflcation Model: MFCM)을 제안하는데, MFCM은 주어진 데이터에서 추출된 특징벡터 전체를 한번에 이용하지 않고 같은 성질들의 특징벡터들끼리 모아서, 여러 단계에 걸쳐서 분류에 이용한다. 학습단계에서, 같은 성질을 가지는 특징벡터 그룹 각각을 이용하는 국지적 분류기의 분류 정확도 산출을 통해 각 특징벡터그룹의 기여도를 측정한다. 분류단계에서는 각 특징벡터 그룹의 기여도에 따라 차등적으로 가중치를 적용하여 최종적인 분류결론을 이끌어 낸다. 본 논문에서 는 MFCM의 개념을 기존의 몇 가지 분류 알고리즘에 적용하고, 음악 장르 분류 문제에 응용하여, 제안된 알고리즘의 유용성에 관한 실험을 수행하였다. 실험의 결과 제안된 MFCM을 이용하는 분류기는 기존의 알고리즘과 비교하여 분류정확도에서 평균적으로 7%-13%의 성능향상을 보여준다. The Multistage Feature-based Classification Model(MFCM) is proposed in this paper. MFCM does not use whole feature vectors extracted from the original data at once to classify each data, but use only groups related to each feature vector to classify separately. In the training stage, the contribution rate calculated from each feature vector group is drew throghout the accurncy of each feature vector group and then, in the testing stage, the final classification result is obtained by applying weights corresponding to the contribution rate of each feature vector group. In this paper, the proposed MFCM algorithm is applied to the problem of music genre classification. The results demonstrate that the proposed MFCM outperforms conventional algorithms by 7%-13% on average in terms of classification accurncy.

국내 대기업의 인적자원개발(HRD) 동향 -대기업 HRD 관리자의 인식을 중심으로-

송영수 ( Young Soo Song ) 한국교육정보미디어학회(구 한국교육정보방송학회) 2007 교육정보미디어연구 Vol.13 No.2

산업시대의 기업 내 인적자원개발(HRD)은 교육훈련(T&D), 조직개발(OD), 경력개발(CD) 등의 영역으로 인식되어 왔으나, 지식정보화 시대로 진입된 최근에는 매우 다양한 의미로 변화되고 있으며, 기업 내 HRD 동향도 인식의 전환 또는 의미의 재발견이 요구되는 시점이다. 본 논문에서는 국내 주요 그룹의 인재개발원에 근무하는 과장급 이상의 간부 및 리더들을 대상으로 최근 HRD 동향을 문헌연구 및 FGI를 통해 개발된 설문문항을 조사한 결과, 종래의 교육훈련(T&D)은 학습과 성과(Learning & Performance)로 전환이 되었고 조직개발은 학습조직(Learning Organization) 및 지식경영(Knowledge Management)으로 확대되었으며, 전문성 강화를 위한 경력개발(CD)로 초점이 전환되었다. HRD의 주요 동향으로는 현장 성과개선 활동의 강화, 차세대 리더 및 핵심인재 양성교육에 초점, 간부 및 경영자의 능력개발 교육 강화, 글로벌 HRD 필요성 강조, 균형감각과 전문성을 갖춘 인재양성, 경영자의 전략적 파트너로서의 HRD, 경영전략을 지원하는 수단으로써의 HRD, 그리고 능동적인 학습에 초점을 두는 것으로 나타났다. 또한 HRD의 주요 대상, 방법, 내용, 평가 등 HRD 활동의 제 분야도 많은 변화가 나타나고 있다. 즉, 리더 및 경영자 양성을 주요 대상으로 온라인 교육이 강화되고 있으며, 핵심가치의 확산과 아울러 교육평가 부문에서도 반응(Reaction)보다는 학습(Learning) 및 현장적용도(Transfer) 중심으로 강조되고 있다. In the industrial era of the 20th century, human resource development (HRD) was categorized into three areas: training & development(T&D), organizational development (OD) and career development(CD). However, in recent years, the digital revolution driven by information technology urges companies to rush into the knowledge-based information era and global era. This research was implemented to analyze HRD trends in Korean large enterprises through literature review, FGI, and survey, As a result, T&D, OD and CD has changed to emphasize learning & performance, learning organization & knowledge management and CD which focuses on generalized specialist. Now, it is necessary to take notice of the fact that HRD sector has changed to emphasize performance improvement rather than focusing on the training itself. As corporate HRD sector is cultivating top talents as the source of competitiveness, it is making a lot of changes in its main target, method, content and assessment. Korean large enterprises that are waging the war for talent have already switched their attention to raise the next generation leaders & managers and revitalize the training method of action learning and blended-learning. Korean large enterprises also emphasize on global HRD as they reinforce the cultivation of manpower that can lead the global management era. In evaluation section, learning (Level 2) & transfer(level 3) has emphasized among 4 levels of Kirkpatrick`s model.

스마트 팩토리 리니어 모션 시스템 시뮬레이션 소프트웨어의 개발

송영수(Young-Soo Song),이명근(Myung-Keun Lee),조경재(Kyung-Jae Joe),송태헌(Tae-Heon Song),노민(Min Rho),성민영(MinYoung Sung) 대한기계학회 2019 대한기계학회 춘추학술대회 Vol.2019 No.11

Linear Motion System (LMS) provides discrete or synchronized precise motion for the workpiece, unlike conventional transport methods. The demand for LMS is increasing with the Industry 4.0, smart factory trends and the spread of flexible production systems. Existing industries have developed software that controls LMS hardware after it has been deployed, because control software cannot be validated without LMS hardware. There was a limit that such development methods were difficult to respond to changes in customers’ demands. In this paper, we propose an LMS simulator that can verify the LMS controller software behavior before the hardware is made. The simulator allows users to manipulate Web-based UI to design the desired simulation model. The simulator communicates with the actual controller and describes the behavior of the LMS by the controller command. Because of the simulation based on the physical engine, it is possible to actually see the LMS actuated by the physical force. Users can derive the desired hardware design through sufficient simulation before hardware is deployed.

仙尾骨部 畸形腫

宋英樹(Young Soo Song),鄭日東(Il Dong Chung) 대한외과학회 1973 Annals of Surgical Treatment and Research Vol.15 No.1

상대적 저용량 furosemide 복용력이 있는 성인에서 발생한 신수질 석회화

송영수 ( Young Soo Song ),신규태 ( Gyu Tae Shin ),정희선 ( Hee Sun Jung ),김현아 ( Hyoun Ah Kim ),박지은 ( Ji Eun Park ),정혁준 ( Hyuck Joon Chung ),김흥수 ( Heung Soo Kim ) 대한내과학회 2005 대한내과학회지 Vol.69 No.-

The long-term use of high dose furosemide is associated with medullary nephrocalcinosis in adults. The recent reports reveals that the development of medullary nephrocalcinosis is more associated with the daily dose of furosemide than the duration of medication. However, dose of furosemide that initiate medullary nephrocalcinosis is not known. We report a case of medullary nephrocalcinosis developed in adult patient taken relatively low dose furosemide. A 28 year-old woman showed hypokalemia, metabolic alkalosis, and medullary nephrocalcinosis on ultrasonographic evaluation. We discovered that she had taken the furosemide since 44 months ago. The average dose of furosemide taken by the patient was 0.26~1.15 mg/kg/day, and this dose was much smaller than recently reported dose of furosemide associated with medullary nephrocalcinosis in adults. Thus one should be alert for the development of medullary nephrocalcinosis in therapeutic dose of long-term furosemide use and educate the possible abuser for the development of medullary nephrocalcinosis. (Korean J Med 69:S919-S923, 2005)

기업 내 셀프리더십 필요역량 탐색

송영수 ( Young Soo Song ) 한국인력개발학회 2011 HRD연구 Vol.13 No.3

본 연구는 국내의 기업 내 셀프리더십 필요역량 도출을 위하여 기업 내 HRD·리더십 현장 전문가 34명을 대상으로 3차에 걸친 델파이 연구를 통해 영역 및 필요역량을 도출하였으며, 타당도를 확보하기 위하여 국내 대기업 구성원 73명을 대상으로 필요역량의 중요도 인식수준에 대한 요인분석을 실시하였다. 주요 연구결과로는 기업 내 셀프리더십은 과업수행 및 성과창출, 자기 및 관계인식, 자기관리의 3개 영역, 필요역량은 커뮤니케이션, 업무책임감, 문제해결, 긍정적사고, 동기부여, 목표수립 등 총 17개로 도출되었다. 본 연구결과는 국내 기업의 셀프리더십 개발을 위하여 요구되는 필요역량을 체계적으로 제시함으로써 구성원의 셀프리더십 역량개발을 위한 지침을 마련하고, 인재양성과 리더십 개발을 담당하는 HRD·리더십 부서에 시사점을 제공할 수 있는 기초자료로 활용될 것으로 기대된다. The purpose of this study is to explore required competencies for self-leadership in large Korean enterprises. 34 HRD and leadership practitioners working in domestic businesses were selected as a group of experts for this study and the delphi method was conducted three times. The factor analysis was applied to see self-leadership required competencies` importance recognition of 73 businessmen. The findings of the study are as follows. First, the self-leadership is analyzed into three domains, such as task performance and creating outcome, self-awareness and awareness of relationship, and self-management. Second, the 17 required competencies for self-leadership are drawn; communication, task responsibility, problem solving, positive thinking, motivation, goal setting, etc. It is expected that the findings from this study will be used to suggest the standard for developing self-leadership competencies, and to grasp the current status of self-leadership, as a basic data for a guide to apply to the practical business.

기업 내 성과개선을 위한 외부 전문코치의 주요 역량 탐색

송영수 ( Young Soo Song ) 한국인력개발학회 2011 HRD연구 Vol.13 No.1

본 연구는 국내기업을 대상으로 활동 중인 전문코치의 주요역량 규명을 목적으로 한다. 이를 위해 (사)한국코치협회와 국제코치연맹(ICF)의 전문코치인증 자격을 취득하고 현재 국내에서 활동 중인 전문코치 17명을 대상으로 3차에 걸친 델파이 연구를 진행하였다. 연구결과, 전문코치의 주요역량군은 코칭철학의 이해, 커뮤니케이션 스킬, 코칭 프로세스 관리, 성과관리 등 4가지 영역으로 구분되었으며, 각 역량군에 따른 세부역량은 다양성 존중, 신뢰 구축, 책임감, 자기성찰, 코칭 윤리 준수, 경청 스킬, 질문 스킬 등 총 18가지로 분석되었다. 이는 ICF의 코칭역량모델(11개역량)에서 제시한 태도나 스킬 중심 역량을 포괄할 뿐만 아니라, 요약(정리)스킬, 코칭 진단도구 활용스킬, 시간관리 스킬 등 7가지 역량을 추가로 분석하였으며, 특히 국내 기업 실정에서 강조하고 있는 성과관리 역량군과 그에 따른 세부역량 5가지를 도출하였다. 본 연구의 결과는 하나의 전문분야로 구축된 외부 전문코치의 주요역량과 그에 따른 세부역량을 제시함으로써 전문코치의 역량진단 및 평가, 육성을 위한 기초자료로 활용될 것으로 기대된다. 또한 기업 내 증대되고 있는 전문코치의 효율적 활용에 시사점을 제공할 것으로 기대된다. The purpose of this study is to identify professional coach`s competencies in Korea. In the study, a three-round delphi method was conducted with 17 certified professional coaches who achieved from KCA(Korea Coach Association) or ICF(International Coach Federation). The result of this study showed that the four domains of professional coach`s competency were divided into understanding of coaching philosophy, communication skill, coaching process management, and performance management. In addition, the 18 required subordinate competencies related to the domain were drawn such as respecting diversity, confidence-building, a sense of responsibility, self-examination, coaching ethics-observance, listening skills and question skills above this. These foundings included not only core competencies in coach`s skill and attitude elicited by ICF coaching competency model but also performance management domain and it`s subdomains emphasized by korean companies today. The results of this study are expected to be a standard of professional coach`s competencies. In addition, the results can to be used as the primary data for developing professional coach`s competencies and to provide implications of foresting and utilizing their competencies.