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척수병증으로 발현한 자발성 콜레스테롤 결정에 의한 색전증 1예
손홍석 대한뇌졸중학회 2008 Journal of stroke Vol.10 No.2
Cholesterol cystal embolism is a serious complication of atheroma. Cholesterol embolism can give rise a various clinical spectrum, depending of the site of the embolism, but neurological manifestation involving spinal cord is extremely rare. We describe a case of cholesterol embolism causing spinal cord infarction presented with myelopathy. A 74-year-old male visited our hospital due to sudden paraparesis and sensory loss below T10 dermatome. Laboratory test revealed renal failure requiring hemodialysis and renal biopsy showed cholesterol cleft emboli in the microvascular space. Myelopathy would be presenting symptom of systemic cholesterol crystal embolism. (Korean J Stroke 2008;10:139-141)
손홍석,김성훈,이승환,이서영,김성은,여민주 대한신경과학회 2009 대한신경과학회지 Vol.27 No.2
Infection with Toxocara canis evokes various symptoms by migration of the larva via hematogenic infiltration, but CNS involvement has rarely been documented. We describe a 63-year-old man who had eosinophilic myelitis associated with T. canis. He had subacute progressive lower body paresthesia. Spine MR revealed that the intramedullary lesion was in the thoracic cord. CSF analysis showed many eosinophils and elevated antibody titers to T. canis. These results indicate that parasitic infection should be considered as a possible cause of subacute myelitis. Infection with Toxocara canis evokes various symptoms by migration of the larva via hematogenic infiltration, but CNS involvement has rarely been documented. We describe a 63-year-old man who had eosinophilic myelitis associated with T. canis. He had subacute progressive lower body paresthesia. Spine MR revealed that the intramedullary lesion was in the thoracic cord. CSF analysis showed many eosinophils and elevated antibody titers to T. canis. These results indicate that parasitic infection should be considered as a possible cause of subacute myelitis.
편측성으로 설계된 하악 유리단 국소의치에서 직접유지장치의 설계 변화에 따른 광탄성 응력 분석에 관한 연구
손홍석,계기성 朝鮮大學校 口腔生物學硏究所 1991 Oral Biology Research (Oral Biol Res) Vol.15 No.-
The purpose of this study was to analyze the magnitude and distribution of stress using a photoelastic model from a unilateral distal extention removable partial dentures with five kinds of the direct retainers, that is, the bilaterally designed bar clasp of the cross-arch lingual bar and the unilaterally designed bar clasp, circumferential clasp, mini-Dalbo attachment, and telescope retainer. A photoelastic model for mandible was made of the epxy resin(PL-1) and hardner (PLH-1) with the acrylic resin teeth used and was coated with plastic cement-1 at the lingual surface of the model, and then five kinds of removable partial dentures were set. A unilateral vertical load of about 16㎏ was applied on the first molar and the stress pattern of the photoelastic model under each condition was analyzed by the reflective circular polariscope. The following results were obtained: 1. The conventional removable partial denture with the bilaterally cross arch lingual bar produced th most favorable stress distribution on the residual ridge and supporting structure of abutment teeth than the unilaterally designed removable partical dentures. 2. The uilaterally designed removable partial denture with the bar clasp produced the stress distribution on the residual ridge, except sligtly higher stress concentration on the supporting structure of the abutment teeth, similar to the conventional removable partial dentrue with the bilaterally designed cross arch lingual bar. 3. On the unilaterally designed removable partial dentures, the bar clasp produced greater stress distribution on the residual ridge and supporting structure of the abutment teeth than the circumferential clasp. 4. On the unilaterally designed removable partial dentures, the mimi-Dalbo attachment produced relatively higher stress concentration on the residual ridge, but produced lesser stress concentration on the supporting structure of the abutment teeth than the other direct retainers. 5. On the unilaterally designed removable partial dentures, the telescope retainer produced uniform stress distribution on the residual ridge, but produced higher stress concentration at the root apex of the terminal abutment tooth than the other direct retainers. 6. On the unilaterally designed removable partial dentures, the circumferential clasp and telescope retainer produced slightly higher stress concentration on the residual ridge and supporting structure of the abutment teeth than the bar clasp and mini-Dalbo attachment.
Metabolic Phenotyping of Berries in Different Six Grape (Vitis vinifera) Cultivars
손홍석,임광세,정현정,양수진,홍영식 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.4
Metabolic behaviors of different grapevine cultivars,grown in the same greenhouse, were characterized through a 1HNMR-based metabolomic approach. Pattern recognition, includingthe principal component analysis, revealed clear dependence ofthe grape metabolome on the grape cultivar. Interestingly, highaccumulations of proline in the purebred grape cultivars of CabernetSauvignon, Merlot, and Chardonnay were found, whereas theproline levels were depleted in the crossbred grape cultivars ofSteuben, Campbell Early (C. E.), and Seibel. Intrinsic levels ofalanine, glutamine, and trans-feruloyl derivative were highest inC. E. cultivar, which grows easily in a wild vineyard, particularlyin Korea, suggesting that their levels play important roles in theimprovement of resistance or adaptation of the plant to environmentalstress, such as freezing stress during the winter season inKorea. The present study highlights that metabolomics is a powerfulapproach for better understanding the differences of intrinsicmetabolic variables of grape berries among various grape cultivarsand their associations with the plant physiological mechanisms.
편측성으로 설계된 하악 유리단 국소의치에서 직접유지장치의 설계 변화에 따른 광탄성 응력 분석에 관한 연구
손홍석,계기성,Son Hong-Suk,Kay Kee-Sung 대한치과보철학회 1992 대한치과보철학회지 Vol.30 No.1
The purpose of this study was to analyze the magnitude and distribution of stress using a photoelastic model from a unilateral distal extention removable partial dentures with five kinds of the direct retainers, that is, the bilaterally designed bar clasp of the cross-arch lingual bar and the unilaterally designed bar clasp, circumferential clasp, mini-Dalbo attachment, and telescope retainer. A photoelastic model for mandible was made of the epoxy resin(PL-1) and hardner (PLH-1) with the acrylic resin teeth used and was coated with plastic cement-1 at the lingual surface of the model, and then five kinds of removable partial dentures were set, A unilateral vertical load of about 16Kg was applied on the first molar and the stress pattern of the photoelastic model under each condition was analyzed by the reflective circular polariscope. The following results were obtained: 1. The conventional removable partial denture with the bilaterally cross arch lingual bar produced the most favorable stress distribution on the residual ridge and supporting structure of abutment teeth than the unilaterally designed removable partial dentures. 2. The unilaterally designed removable partial denture with the bar clasp produced the stress distribution on the residual ridge, except sligtly higher stress concentration on the supporting structure of the abutment teeth, similar to the conventional removable partial denture with the bilaterally designed cross arch lingual bar. 3. On the unilaterally designed removable partial dentures, the bar clasp produced greater stress distribution on the residual ridge and supporting structure of the abutment teeth than the circumferential clasp. 4. On the unilaterally designed removable partial dentures, the mimi-Dalbo attachment produced relatively higher stress concentration on the residual ridge, but produced lesser stress concentration on the supporting structure of the abutment teeth than the other direct retainers. 5. On the unilaterally designed removable partial dentures, the telescope retainer produced uniform stress distribution on the residual ridge, but produced higher stress concentration at the root apex of the terminal abutment tooth than the other direct retainers. 6. On the unilaterally designed removable partial dentures the circumferential clasp and telescope retainer produced slightly higher stress concentration on the residual ridge and supporting structure of the abutment teeth than the bar clasp and mini- Dalbo attachment.