외상성 공막 천공 환자에서 시행한 자가테논낭이식 1예

배지현,성현경,김하경,남우호,Ji Hyun Bae,Hyun Kyoung Seong,Ha Kyoung Kim,Woo Ho Nam 대한안과학회 2008 대한안과학회지 Vol.49 No.10

Purpose: To report the use of autologous Tenon’s capsule graft for repair of scleral defects caused by traumatic scleral perforation. Case summary: An 81-year-old man presented with loss of vision in his right eye after a perforating injury caused by a cow horn. Examination showed a laceration of the sclera at 12 o’clock approximately 5~6 mm in length, and a uveal tissue was prolapsed into the wound. The best corrected visual acuity was 0.1. Primary repair of the eye was insufficient because of tissue loss. The inferonasal Tenon’s capsule graft was carefully dissected from the sclera and tailored to fit the defect. The graft was covered with a conjunctival flap. The scleral defect was successfully closed with the autologous Tenon’s capsule graft. Three months after grafting, phacoemulsification with intraocular lens implantation was performed. Conclusions: Autologous Tenon’s capsule graft is an effective measure to repair traumatic scleral defects and is useful when patch grafts are unexpectedly needed. J Korean Ophthalmol Soc 2008;49(10):1706-1710

교정나이 3세가 된 미숙아의 굴절이상, 약시 및 사시

배지현,최동규,Ji Hyun Bae,Dong Gyu Choi 대한안과학회 2010 대한안과학회지 Vol.51 No.10

Purpose: To evaluate the refractive status, anisometropia, amblyopia and strabismus in 3-year-old premature children. Methods: A total of 161 eyes from 82 premature infants were retrospectively reviewed and divided into three groups according to the presence of retinopathy of prematurity (ROP) and treatment; Group 1 (68 eyes): without ROP, Group 2-1 (32 eyes): spontaneously regressed ROP, and Group 2-2 (61 eyes): regressed ROP with treatment. The incidences and clinical features of refractive errors, anisometropia, amblyopia and strabismus at the age of three years were compared among the three groups. Results: The incidences of myopia, astigmatism, anisometropia and the severity of myopia increased according to the presence of ROP and treatment (p = 0.03, 0.02, 0.001, and 0.04, respectively). There were no significant differences in the incidences of hyperopia among the three groups; however, the severity of hyperopia in Group 2-2 was higher than those in the other two groups (p = 0.01). Patients in Group 1 had better best corrected visual acuity (BCVA) compared with those of the other two groups (p < 0.001). However, no significant differences in the incidences of strabismus or amblyopia among the three groups (p = 0.80 and 0.85, respectively) were found, and the ratio of esotropia : exotropia was 1:1.3. Conclusions: Regular ocular examination should be required in children who were born prematurely in order to detect and treat ophthalmologic problems such as refractive errors, amblyopia and strabismus. J Korean Ophthalmol Soc 2010;51(10):1385-1391

매실 추출물을 함유한 기능성 음료 개발

배지현,김기진,김성미,이원재,이선장,Bae, Ji-Hyun,Kim, Ki-Jin,Kim, Sung-Mi,Lee, Won-Jae,Lee, Sun-Jang 한국식품과학회 2000 한국식품과학회지 Vol.32 No.3

본 연구에서는 매실 추출물을 0.5%, 5%, 10%, 15% 및 20% 함유한 매실음료를 제조하여 이들의 위암, 대장암, 간암 및 자궁암 세포주 증식에 미치는 항암효과를 MTT(3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay, 세포독성 test 및 현미경 관찰 등을 통하여 조사해 보았다. 또한 12주간의 매실음료 섭취가 운동선수들의 체내 수분대사 조절 능력에 미치는 영향을 비교해 보았다. 20% 매실 추출물을 함유한 매실음료의 경우 위암 세포주인 SNU-16에 대해 증식억제 효과를 보였고, $1000\;{\mu}g/mL$ 농도에서는 유의적인 세포수의 감소를 관찰할 수 있었다. 매실음료를 배양액에 첨가하여 6일간 배양시켰을 때 SNU-16 세포주의 형태학적 변화를 볼 수 있었고 fibroblast에는 아무런 변화가 없었다. 매실음료를 섭취한 운동선수들의 경우 혈중 Na, K 및 Cl농도는 안정시에 비해서 운동 중 회복기에 유의하게(P<0.05) 증가하였으며 12 주간의 음료섭취 후 두 그룹 모두 거의 동일한 변화양상을 나타내었다. This study was performed to investigate the cytotoxic effect of the Prunus mume extracts containing beverages on the growth of SNU-16 gastric cancer cell, SNU-C2A colon cancer cell, SNU-449 liver cancer cell and HeLa cervical cancer cell. The inhibitory effect on the growth of the cancer cell lines was examined by MTT(3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay, cytotoxicity test and microscopy. Also this study aimed to compare the changes of blood electrolytes and osmolarity during submaximal exercise for the intake of the Prunus mume extracts containing beverages. 20% Prunus mume extracts containing beverage exhibited the greatest inhibitory effect on the growth of SNU-16 and significantly inhibited at the concentration of $1000\;{\mu}g/mL$ in the MTT assay. Morphological changes in SNU-16 which treated with the same beverage were observed under inverted microscope. The change of blood electrolytes and osmolarity during submaximal exercise showed no significant differences between before and after intake of the beverage in both groups.

식중독 유발 세균의 증식에 미치는 겨우살이 추출물의 영향

배지현,노숙희,박효정,Bae Ji-Hyun,No Suck-Hee,Park Hyo-Jung 동아시아식생활학회 2005 동아시아식생활학회지 Vol.15 No.2

This study was performed to investigate the antimicrobial effect of the Viscum album var. coloratum extracts against food-borne pathogens. First, the Viscum album var. coloratum was extracted with methanol at room temperature and the fractionation of the methanol extracts was carried out by using petroleum ether, chloroform, and ethyl acetate, and methanol, respectively. The antimicrobial activity of the Viscum album var. coloratum extracts was determined by using a paper disc method against food-borne pathogens and food spoilage bacteria. The petroleum ether extracts of Viscum album var. coloratum showed the highest antimicrobial activity against Bacillus cereus and Shigella dysenteriae. Synergistic effect in inhibition was observed when Viscum album var. coloratum extract was mixed with Perillae folium extract as compared with each extract alone. Finally, the growth inhibition curves were determined by using petroleum ether extracts of Viscum album var. coloratum against Bacillus cereus and Shigella dysenteriae. The petroleum ether extract of Viscum album var. coloratum had strong antimicrobial activity against Bacillus cereus at the concentration of 5,000 ppm. At this concentration, the growth of Bacillus cereus was retarded more than 24 hours and up to 12 hours for Shigella dysenteriae. In conclusion, the petroleum ether extracts of Viscum album var. coloratum inhibit efficiently Bacillus cereus and Shigella dysenteriae.

식중독유발 세균의 증식에 미치는 백화사설초 추출물의 영향

배지현(Ji-Hyun Bae) 한국식품영양과학회 2005 한국식품영양과학회지 Vol.34 No.1

본 연구에서는 식중독 유발세균에 대한 항균활성이 우수한 천연 항균성 물질을 검색하기 위해 예로부터 민간과 한방에서 널리 이용되어 온 백화사설초를 각종 유기용매로 추출하여 식중독 유발세균에 대한 항균활성을 조사해 보았다. 백화사설초를 petroleum ether, chloroform, ethly acetate, methanol를 이용하여 실온에서 각각 용매별로 계통 분획하고, 열수추출물을 얻은 후, 9종의 식중독 유발세균(Staphylococcus aureus, Bacillus cereus, Salmonella enteritidis, Shigella flexneri, Escherichia coli, Salmonella Typhimurium, Shigella dysenteriae, Pseudomonas aeruginosa, Shigella sonnei)에 대하여 항균효과를 조사하였다. 백화사설초 추출물의 농도별 항균 활성 검색에서는 백화사설초의 methanol 추출물이 가장 큰 항균 효과를 보였으며 S. aureus와 S. flexneri가 가장 민감하게 반응하는 균주였다. 백화사설초의 methanol 추출물과 산두근의 ethyl acetate 추출물을 혼합하여 항균력을 측정해 본 결과 두 추출물을 섞어 첨가했을 경우가 단독으로 사용했을 시보다 상승효과를 나타내었다. 또한 백화사설초의 methanol 추출물이 식중독 유발세균의 성장에 미치는 효과를 검정하기 위해 S. aureus 및 S. Typhimurium의 배양액에 백화사설초의 methanol 추출물을 각각 4,000 ppm 농도로 첨가했을 시, S. aureus의 생육이 36시간 이상까지 억제됨을 관찰할 수 있었고, S. Typhimurium의 생육도 24시간까지 지연시킬 수 있었다. 이상의 결과 백화사설초의 methanol추출물은 S. aureus와 S. Typhimurium의 성장을 효과적으로 억제시킴을 알 수 있었다. This study was performed to investigate the antimicrobial effect of the Hedyotis diffusa extracts against food-borne pathogens. First, the Hedyotis diffusa was extracted with methanol at room temperature and the fractionation of the methanol extracts was carried out by using petroleum ether, chloroform, and ethyl acetate, and methanol respectively. The antimicrobial activity of the Hedyotis diffusa extracts was determined by using a paper disc method against food-borne pathogens and food spoilage bacteria. The methanol extracts of Hedy- otis diffusa showed the highest antimicrobial activity against Staphylococcus aureus and Shigella flexneri. Synergistic effect in inhibition was observed when Hedyotis diffusa extract was mixed Sophora subprostrata extract as compared to each extracts alone. Finally, the growth inhibition curves were determined by using ethyl acetate extracts of Hedyotis diffusa against Staphylococcus aureus and Salmonella Typhimurium. The methanol extract of Hedyotis diffusa had strong antimicrobial activity against Staphylococcus aureus at the concentration of 4,000 ppm. At this concentration, the growth of Staphylococcus aureus was retarded more than 36 hours and up to 24 hours for Salmonella Typhimurium. In conclusion, the methanol extracts of Hedyotis diffusa inhibit efficiently Staphylococcus aureus and Salmonella Typhimurium.

대안교육특성화고등학교의 선택교육과정 편성·운영의 실태와 시사점 탐색

배지현(Bae Ji Hyun) 학습자중심교과교육학회 2015 학습자중심교과교육연구 Vol.15 No.7

본 연구는 대안교육특성화고등학교의 선택교육과정 특징을 분석함으로써 고등학 교 선택교육과정 운영에의 시사를 탐색하려는 목적을 지닌다. 이를 위해 2014년 현 재 24개에 달하는 대안교육특성화고의 편성된 교육과정을 분석하여 일반적인 경향 을 도출하고 심층면담 등의 질적 연구를 통해 선택교육과정 운영상의 주요 쟁점을 추출하였다. 그 결과 대안교육특성화고에서는 기초, 탐구, 체육·예술, 생활·교양 전 영역에서 ‘학교선택’과 ‘학생선택’을 골고루 운영하고 있었고, 다양한 특성화 과목의 개설과 학생의 과목(종류 및 개수) 선택권 부여를 통해 개방적인 선택교육과정을 편 성하고 있었다. 또 본 연구에서는 선택교육과정 운영과 관련해서 ‘학교선택’, ‘학생선 택’, ‘과목선택권’이라는 주제로 7개의 쟁점들이 도출되었다. 더불어 대안교육특성화 고의 선택교육과정 운영의 실제가 주는 시사로 ① 선택교육과정 운영에 있어 단위 학교의 의지와 철학의 중요성, ② 선택의 주체와 목적, 대상에 있어 다각화의 전망, ③ 시기별 종합적인 지원 방안의 필요성, ④ 대안교육특성화고의 교육과정 운영의 자율성 보장 및 책무성 제고 등을 논하였다. The purpose of this study is to research the suggestion to the elective curriculum of high school by analyzing the features of the organization and implementation of the elective curriculum in Specialized High School for Alternative Education, or SHSAE. For it, this study has abstracted main issues in the implementation of elective curriculum through case study and qualitative analyzation and explored general tendencies of elective curriculum which was organized for SHSAE which numbers up to 24, as of 2014. As for the result, in SHSAE, they had actively organized programs for elective curriculum, allowing the students to select their subjects ―kind and number― and opening various specialized subjects, by various operation of students selection and schools selection in all fields of subjects; basic, inquiry, PE & arts, and life living & liberal arts. And, related to student’s choice, school s choice and students’ rights to choose their subjects, seven main issues on the implementation of elective curriculum are analyzed. Finally, as for the organization and implementation of elective curriculum, this study suggests as follows; ① the importance of philosophy and intention of individual schools, ② prospects on diversification on main agent, object and purpose of choice, ③ needs of generalized supporting for each period?short, medium and long term, and ④ assurance for autonomy on curriculum management of SHSAE.

잠재적 교육과정의 재개념화를 위한 잠재적 교육과정 이론에 대한 평가

배지현 ( Ji Hyun Bae ) 한국교육과정학회 2013 교육과정연구 Vol.31 No.1

The concept of hidden curriculum has been interpreted in various ways since it appeared 40 years ago. One issue about the concept of hidden curriculum is a controversy upon whether it is ``subordinate`` to the manifest curriculum or not. The aims of this study are to analyze the limit of this controversy about the hidden curriculum and reconceptualize it from an angle of class activities. According to this study, oppositive theorists interpreted the concept of hidden curriculum in their separate ways. That is to say, though theorists use the same term hidden curriculum, they have very different meanings. The controversy upon whether hidden curriculum is subsidiary or not is unproductive dispute, because theorist argue this problem while using different assumptions about meaning of hidden curriculum. This study makes a new suggestion for reconceptualization of the hidden and manifest curriculum from an angle of class activities as follows; The hidden curriculum is educational contents of ``tacit and personal mode``, compared with the manifest curriculum is educational contents of ``formal and public mode``. Based on the this alternate conception of curriculum, it can be said that the hidden curriculum and manifest curriculum has the following three characters. First, the former is ``educational contents as substance``, and the latter is ``educational contents as formal descriptor of the hidden curriculum``. Second, the former is ``superfluous educational contents``, and the latter is ``formalized part of the hidden curriculum``. Third, the former makes the manifest curriculum exist and modifies it, and the latter sparks and advances the hidden curriculum.

니체의 영원회귀의 교육적 함의: ‘신체-자기’의 변신을 중심으로

배지현 ( Bae Ji-hyun ),김재춘 ( Gim Chae-chun ) 한국교육철학학회(구 교육철학회) 2018 교육철학연구 Vol.40 No.3

이 연구는 니체의 영원회귀 사상의 의미를 고찰하고 이것의 교육적 함의를 탐색하기 위한 것이다. 본 글에서는 영원회귀의 의미를 필연성과 교의성이라는 두 차원에서 밝히고, 영원회귀에 함축된 자기극복과 변신의 메시지를 니체의 ‘나’의 대한 논의인 신체-자기론과 망각의 개념을 통해 드러냈다. 우연히 생성ㆍ변전하는 삶만이 필연적으로 회귀될 것이라는 신적 계시 앞에서 영원회귀는 허무주의에 빠지지 않고 오히려 무의미한 현존을 긍정ㆍ사랑하는 운명애의 태도를 갖는 것으로 해석하였다. 동시에 ‘무수히 다시 살기를 바랄만큼의 삶’을 창조하기 위해 신체-자기의 창조적 죽음인 ‘변신’을 감행하고 ‘결정적 한 번의 나’를 망각함으로써 ‘무수한 나들’로 가역적으로 회귀시키는 실천으로 해석하였다. 니체의 이러한 영원회귀 사상이 갖는 교육적 함의는 다음과 같다. 첫째, 학습자의 성장과 변화는 ‘자아의 동일성 구축’과 ‘신체-자기의 변신’ 간의 길항 작용 및 대체 과정으로 새롭게 이해할 수 있다. 둘째, 학습자의 변화나 성장을 돕는 교육에서 ‘적극적 망각’ 또는 ‘기억의 파괴’는 현행 가치와는 완전히 다른 새로운 가치를 실험하는 ‘시도하는 자’ 또는 ‘창조자’에게 중요한 요소이다. 셋째, 영원회귀와 변신은 교육의 내적 가치를 드러내주는 ‘운명애로서의 교육'의 메타포를 산출하며, 이러한 메타포는 교육의 외적 가치에 찌든 교육학 논의에서 새로운 교육의 이미지로 작용할 수 있다. This study is to examine Nietzsche's meaning of eternal return and to explore its educational implications. This article reveals the meaning of the eternal recurrence in two dimensions of inevitability and orthodoxy, and investigates the message of self-surpassing and meta-morphosis implied in the eternal return through the concepts of body-self and oblivion. In addition, this paper interprets eternal return as amor-fati that affirms non-sense existence rather than falling into the nihilism when the divine revelation demands that only the life that is mobilized by chance will inevitably return. At the same time, in order to create a life that would desire to live a myriad of lives, this paper interprets eternal return as a practice of reversing the body-self's creative death or ‘transformation of the body-self’. It is shown that Nietzsche's eternal return has the following educational implications: First, the learner's growth can be newly understood as an endless process of antagonism and substitution between self-identity and body-self. Second, oblivion or 'destruction of memory' is an important factor for a 'versucher' who experiments or tempts new values completely different from the current value in education that helps learners grow. Third, ‘education as amor-fati’ that reveals the inner value of education based on the concepts of eternal return and amor-fati can serve as a new image of education.

초등 수학영재와 일반학생의 정의적 특성과 수학적 추론 능력과의 관계 비교

배지현 ( Ji Hyun Bae ),류성림 ( Sung Rim Ryu ) 한국수학교육학회 2016 初等 數學敎育 Vol.19 No.2

본 연구는 초등 수학영재와 일반학생을 대상으로 정의적 특성과 수학적 추론 능력에서 어떠한 차이가 있는가를 알아보고, 이를 바탕으로 초등 수학영재와 일반학생의 정의적 특성과 수학적 추론 능력과의 관계를 비교ㆍ분석하는 것이다. 연구대상은 5학년의 영재 97명과 일반학생 144명이다. 검사도구로는 정의적 특성 검사지와 추론능력 검사지를 사용하였다. 본 연구의 결론은 다음과 같다. 첫째, 수학영재는 일반학생보다 정의적 특성의 하위 요소인 학업적 자아개념, 태도, 흥미, 수학불안, 학습습관에서 모두 긍정적인 인식을 지녔고, 수학적 추론 능력에서도 일반학생보다 능력의 정도가 높았다. 또한 수학영재는 정의적 특성의 학업적 자아개념, 태도, 흥미, 학습습관은 추론 능력과 정적인 상관관계를 가지고 있었으며 수학불안은 부적인 상관관계를 가지고 있었다. 둘째, 수학영재는 정의적특성의 하위 요소 중 수학불안이 수학적 추론 능력에 부정적인 영향을 미치는 것으로 나타났는데, 이를 통해 수학영재들의 추론 능력을 향상시키기 위해서는 수학 불안을 줄이는 실질적인 여러 방안을 모색할 필요가 있음을 알수 있다. 셋째, 일반학생들은 정의적 특성의 하위 요소 중흥미가 수학적 추론 능력에 영향을 주는 것으로 나타났는데, 따라서 교실 수업에서 일반학생들의 수학교과에 대한 흥미를 높여주는 적절한 방법에 대한 교수ㆍ학습 구안 및 적용을 통해 수학적 추론 능력의 향상을 도모할 수 있다. The purpose of this study is to measure the differences in affective characteristics and mathematical reasoning ability between gifted students and non-gifted students. This study compares and analyzes on the relations between the affective characteristics and mathematical reasoning ability. The study subjects are comprised of 97 gifted fifth grade students and 144 non-gifted fifth grade students. The criterion is based on the questionnaire of the affective characteristics and mathematical reasoning ability. To analyze the data, t-test and multiple regression analysis were adopted. The conclusions of the study are synthetically summarized as follows. First, the mathematically gifted students show a positive response to subelement of the affective characteristics, self-conception, attitude, interest, study habits. As a result of analysis of correlation between the affective characteristic and mathematical reasoning ability, the study found a positive correlation between self-conception, attitude, interest, study habits but a negative correlation with mathematical anxieties. Therefore the more an affective characteristics are positive, the higher the mathematical reasoning ability are built. These results show the mathematically gifted students should be educated to be positive and self-confident. Second, the mathematically gifted students was influenced with mathematical anxieties to mathematical reasoning ability. Therefore we seek for solution to reduce mathematical anxieties to improve to the mathematical reasoning ability. Third, the non-gifted students that are influenced of interest of the affective characteristics will improve mathematical reasoning ability, if we make the methods to be interested math curriculum.

쇠비름 추출물이 신생아 장염 유발 미생물에 미치는 영향

배지현 ( Ji Hyun Bae ) 한국식품영양학회 2012 韓國食品營養學會誌 Vol.25 No.2

본 연구에서는 신생아 질환과 사망 원인 중 첫 번째에 해당하는 설사의 주된 원인균인 C. jejuni와 기타 장내 염증 유발 유해 세균에 대한 쇠비름 추출물의 항균력을 검증하였다. 과거부터 민간이나 한방에서 널리 사용되어져 온 쇠비름은각종 항균 효과나 항염증, 항암 효과 등이 있는 것으로 알려져있다, 쇠비름을 각종 유기용매와 열수로 추출하여 Salmonellatyphimirium, Salmonella enteriditis, Shigella dysenteriae, Shigellaflexneri, Shigella sonnei 및 C. jejuni에 대한 항균활성을 조사해 본 바, 쇠비름의 ethylacetate 추출물 및 열수 추출물이 이들에 대한 항균력을 나타내었다. 쇠비름의 ethylacetate 추출물이 10 ㎎/㎖ 농도에서 Salmonella typhimurium에 대해 가장높은 항균력을 나타내었고, 열수 추출물도 유사한 항균성을 나타내었다, C, jejuni에 대한 쇠비름 열수 추출물의 MIC 범위는 10~20 ㎎/㎖였으며, MIC50은 10 ㎎/㎖, MIC90은 20 ㎎/㎖이었다, 쇠비름 열수 추출물은 10 ㎎/㎖ 이상의 농도에서C. jejuni에 대한 강한 항균력을 나타내 보였다. 또한 액체 배지에 배양한 C. jejuni에 대해 쇠비름의 열수 추출물이 10~20㎎/㎖ 농도에서 36시간까지 성장 억제 효과를 보였다. Diarrheal diseases constitute one of the major causes of morbidity and mortality in infants and young children globally. One of the main microorganisms causing diarrheal diseases is Campylobacter jejuni. For treatment of these diseases, Portulaca oleracea has been widely used as a folk remedy for a long time. This study was performed to investigate the antimicrobial activity of P. oleracea against gastroenteritis pathogens including C. jejuni. P. oleracea was extracted with petroleum ether, chloroform, ethylacetate, methanol, and hot water. The antimicrobial activity of the P. oleracea extracts was determined using the paper disc method, minimum inhibitory concentration, and the liquid culture method. The 10 ㎎/㎖ ethylacetate extract showed the strongest antimicrobial activity against Salmonella typhimurium, Salmonella enteriditis, and Shigella spp. The hot water extract from P. oleracea showed the highest anti-microbial activity against C. jejuni at 10~20㎎/㎖. The hot water extract of P. oleracea retarded the growth of C. jejuni for 36 hr at 42℃.