우라늄 제거를 위한 실험실 규모 동전기 장치의 개선 방안

박혜민,김계남,김승수,김완석,박욱량,문제권,Park, Hye-Min,Kim, Gye-Nam,Kim, Seung-Soo,Kim, Wan-Suk,Park, Uk-Ryang,Moon, Jei-Kwon 한국방사성폐기물학회 2013 방사성폐기물학회지 Vol.11 No.2

The original pilot-scale electrokinetic equipment suitable to soil contamination characteristics of Korean nuclear facility sites was manufactured for the remediation of soil contaminated with uranium. During the experiment with the original electrokinetic equipment, many metal oxides were generated and were stuck on the cathode plate. The uranium removal capability of the original electrokinrtic equipment was almost exhausted because the cathode plate covered with metal oxides did not conduct electricity in the original electrokinetic equipment. Therefore, the original electrokinetic equipment was improved. After the remediation experience for 25 days using the improved electrokinetic remediation equipment, the removal efficiency of uranium from the soil was 96.8% and its residual uranium concentration was 0.81 Bq/g. When the initial uranium concentration of soil was about 50 Bq/g, the electrokinetic remediation time required to remediate the uranium concentration below clearance concentration of 1.0 Bq/g was about 34 days. When the initial uranium concentration of soil was about 75 Bq/g, the electrokinetic remediation time required to remediate below 1.0 Bq/g was about 42 days. When the initial uranium concentration of soil was about 100 Bq/g, the electrokinetic remediation time required to remediate below 1.0 Bq/g was about 49 days. 방사능 오염 토양 복원을 위해 실험실 규모의 동전기 복원장치를 제작하여 가동 하던 중 토양 내 존재하던 금속이온의 용출로 금속 산화물이 발생하여 음극의 전류 흐름을 차단하는 문제가 발생하였다. 전류의 차단으로 토양 내 우라늄 제거 능력이 상실되어 이러한 문제를 해결하는 해결 방안을 모색하여 개선된 동전기 복원 장치를 제작하였다. 개선된 실험실 규모 동전기 복원 장치를 이용하여 토양복원 실험을 25 일간 수행 하였을 때 우라늄 잔류 농도는 0.81 Bq/g으로 약 96.8%의 제거 효율을 보였으며, 초기 우라늄 농도 50 Bq/g 일 때 우라늄 규제 해제 농도인 1 Bq/g 이하로 제거 되기 까지는 34 일의 복원 기간이 필요하고, 초기 우라늄 농도 75 Bq/g, 100 Bq/g 일 때 각 42 일, 49 일이 필요한 것으로 나타났다.

토픽모델링을 이용한 국내 미세먼지 연구 분류 및 연구동향 분석

박혜민,김태용,권대웅,허준용,이주연,양민준,Park, Hyemin,Kim, Taeyong,Kwon, Daewoong,Heo, Junyong,Lee, Juyeon,Yang, Minjune 대한원격탐사학회 2022 大韓遠隔探査學會誌 Vol.38 No.5

The particulate matter (PM) has emerged as a hot topic around the world as it has been reported that PM is related to an increase in mortality and prevalence rates. In South Korea, the importance of PM has been recognized since the late 1990s, and various studies on PM have been conducted. This study investigated the PM research topics and trends for papers (D=2,764) published in Research Information Sharing Service (RISS) using topic modeling based on Latent Dirichlet Allocation (LDA). As a result, a total of 10 topics were identified in the whole papers, and the PM research topics were classified as 'PM reduction (Topic 1)', 'Government policy and management (Topic 2)', 'Characteristics of PM (Topic 3)', 'PM model (Topic 4)', 'Environmental education (Topic 5)', 'Bio (Topic 6)', 'Traffic (Topic 7)', 'Asian dust (Topic 8)', 'Indoor PM (Topic 9)', 'Human risk (Topic 10)'. In particular, the proportion of papers on topics 'Government policy and management (Topic 2)', 'PM model (Topic 4)', 'Environmental education (Topic 5)', and 'Bio (Topic 6)' to the toal number of papers increased over time (linear slope > 0). The results of this study provide the new literature review methodology related to particulate matter and the history and insight. 전 세계적으로 미세먼지(particulate matter, PM)와 사망률 및 유병률 증가의 관련성이 보고되면서 다양한 연구가 수행되었으며, 우리나라에서는 1990년대 후반을 기점으로 PM에 대한 중요성을 인식하고, PM에 대한 다양한 연구가 수행되었다. 본 연구에서는 '미세먼지' 관련 연구들의 주제를 분류하고, 각 주제별 연구 동향을 확인하기 위해 Research Information Sharing Service (RISS)에 게재된 미세먼지 관련 2,764편의 논문을 대상으로 Latent Dirichlet Allocate (LDA) 분석을 수행하였다. 연구 결과, 총 10개의 주제로 분류하는 것이 가장 적합하였으며, 미세먼지 관련 연구주제는 '미세먼지 저감(Topic 1)', '정부 정책 및 관리(Topic 2)', '미세먼지 특성(Topic 3)', '미세먼지 모델(Topic 4)', '환경교육(Topic 5)', '바이오(Topic 6)', '교통수단(Topic 7)', '황사(Topic 8)', '실내 미세먼지 오염(Topic 9)', '인체 위해성(Topic 10)'의 주제로 분류할 수 있었다. 특히, '정부 정책 및 관리(Topic 2)', '미세먼지 모델(Topic 4)', '환경교육(Topic 5)'. '바이오(Topic 6)' 관련 연구주제들이 시간에 따라 전체 논문에 대한 비율이 증가하는 추세를 보여 성행하는 것을 확인하였다(linear slope>0). 본 연구의 결과는 미세먼지 관련 다양한 분야의 연구자들에게 새로운 문헌 고찰의 방법론을 제시하고, 미세먼지 분야의 역사와 발전에 대한 이해를 제공했음에 의의가 있다.

Effects of Induction Culture on Osteogenesis of Scaffold-Free Engineered Tissue for Bone Regeneration Applications

박혜민,김선화,최병현,Sang-Hyug Park 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.2

BACKGROUND: Restoration of the bone defects caused by infection or disease remains a challenge in orthopedic surgery. In recent studies, scaffold-free engineered tissue with a self-secreted extracellular matrix has been proposed as an alternative strategy for tissue regeneration and reconstruction. Our study aimed to engineer and fabricate self-assembled osteogenic and scaffold-free tissue for bone regeneration. METHODS: Osteogenic scaffold-free tissue was engineered and fabricated using fetal cartilage-derived progenitor cells, which are capable of osteogenic differentiation. They were cultured in osteogenic induction environments or using demineralized bone powder for differentiation. The fabricated tissue was subjected to real-time qPCR, biochemical, and histological analyses to estimate the degree of in vitro osteogenic differentiation. To demonstrate bone formation in an in vivo environment, scaffold-free tissue was transplanted into the dorsal subcutaneous site of nude mice. Bone development was monitored postoperatively over 8 weeks by the observation of calcium deposition in the matrix. RESULTS: In the in vitro experiments, engineered osteogenically induced scaffold-free tissue demonstrated three-dimensional morphological characteristics, and sufficient osteogenic differentiation was confirmed through the quantification of specific osteogenic gene markers expressed and calcium accumulation within the matrix. Following the evaluation of differentiation efficacy, in vivo experiments revealed distinct bone formation, and that blood vessels had penetrated the fabricated tissue. CONCLUSION: The novel engineering of scaffold-free tissue with osteogenic potential can be used as an optimal bone graft substitute for bone regeneration.

아스팔트 혼합물의 골재 간극률 예측을 위한 기계학습 프레임워크

박혜민,나일호,김현환,지봉준,Hyemin Park,Ilho Na,Hyunhwan Kim,Bongjun Ji 한국지반신소재학회 2024 한국지반신소재학회 논문집 Vol.23 No.1

The Voids in the Mineral Aggregate (VMA) within asphalt mixtures play a crucial role in defining the mixture's structural integrity, durability, and resistance to environmental factors. Accurate prediction and optimization of VMA are essential for enhancing the performance and longevity of asphalt pavements, particularly in varying climatic and environmental conditions. This study introduces a novel machine learning framework leveraging ensemble machine learning model for predicting VMA in asphalt mixtures. By analyzing a comprehensive set of variables, including aggregate size distribution, binder content, and compaction levels, our framework offers a more precise prediction of VMA than traditional single-model approaches. The use of advanced machine learning techniques not only surpasses the accuracy of conventional empirical methods but also significantly reduces the reliance on extensive laboratory testing. Our findings highlight the effectiveness of a data-driven approach in the field of asphalt mixture design, showcasing a path toward more efficient and sustainable pavement engineering practices. This research contributes to the advancement of predictive modeling in construction materials, offering valuable insights for the design and optimization of asphalt mixtures with optimal void characteristics.

컨조인트 분석을 이용한 지식정보 데이터베이스 서비스 품질에 대한 고객 선호도 조사

박혜민(Hyemin Park),박희준(Heejun Park),백민호(Minho Baek),박종우(Jongwoo Park) 한국IT서비스학회 2008 한국IT서비스학회지 Vol.7 No.2

  This research is to study the core factors for knowledge information database service and very important database service quality factors to improve customer satisfaction. The database service quality has been critical issue rather than just information service in these days, because the qualitative aspect is becoming more important factors rather than quantitative aspect. As database service quality has been influenced by satisfaction of database user, it needs to try to get excellent results by enhancing ability to obtain information. In order to satisfy this condition, it needs to measure database service quality more accurately first. In this study, we apply conjoint analysis to measure how much to give quality condition to achieve customer satisfaction.

Alemtuzumab을 이용한 이차성 순적혈구 빈혈의 치료

박혜민 ( Hye Min Park ),임재욱 ( Jae Uk Im ),박주환 ( Ju Hwan Park ),김은혜 ( En Hye Kim ),전홍길 ( Hong Gil Jun ),박재후 ( Jae Hoo Park ),김혁 ( Hawk Kim ) 대한내과학회 2013 대한내과학회지 Vol.85 No.2

Pure red cell aplasia (PRCA) in adults is usually idiopathic, although some underlying conditions can cause PRCA. Immunosuppressive therapy (IST) is used to treat PRCA, but IST has side effects and may fail. The anti-CD52 monoclonal antibody alemtuzumab (ALM) was recently used to successfully treat therapy-resistant PRCA. We herein report successful treatment of secondary PRCA after erythropoietin therapy using ALM and cyclosporin A (CsA) in one patient. The total dose of ALM was 60 mg over 3 days (10, 20, and 30 mg, respectively) plus CsA for at least 6 months. The patient achieved a complete response 18 months after ALM-CsA treatment and his treatment could be changed to a different erythropoietin stimulating agent. (Korean J Med 2013;85:214-217)

철 전극 전기분해를 이용한 지하수 중의 질산성질소 제거

박혜민 ( Hye Min Park ),신자원 ( Ja Won Shin ),주경민 ( Kyung Min Joo ),박주양 ( Joo Yang Park ) 한국물환경학회 ( 구 한국수질보전학회 ) 2008 공동 추계학술발표회 Vol.2008 No.-

SEM-EDS와 Micro-Raman Spectrometer를 이용한 생수 내 미세플라스틱 식별 연구

박혜민(Hyemin Park),김고은(Goeun Kim),허준용(Junyong Heo),김수빈(Subeen Kim),양민준(Minjune Yang) 대한지질학회 2019 대한지질학회 학술대회 Vol.2019 No.10

KoBART 모델과 CNN 모델의 가중평균 앙상블을 이용한 멀티모달 감정인식 분류 모델 개선

박혜민(Heymin Park) 한국정보과학회 2023 한국정보과학회 학술발표논문집 Vol.2023 No.6

신고배(Pyrus pyrifolia Nakai)를 이용한 배술 제조 과정 중 성분 변화

박혜민(Hae-Min Park),이가순(Ka-Soon Lee),홍종숙(Jong-Sook Hong),오만진(Man-Jin Oh) 충남대학교 농업과학연구소 2009 농업과학연구 Vol.36 No.2

8종의 효모를 이용하여 담금한 후 배술의 pH, 산도, 에탄올 및 당도의 변화 및 기호도를 조사한 결과 사용된 효모 모두 발효가 지속되면서 일정기간까지 pH는 감소하였으며 산도는 증가하였고 에탄올함량은 발효 12일까지 증가하였고 당도는 12일까지 지속적으로 감소하였다. 효모의 종류에 따라 제조된 배술에 대한 기호도를 조사한 결과, 에탄올 생성량이 가장 높았던 처리구인 효모 B처리구에서 20-30대와 50-60대 연령층을 가진 관능요원 모두 기호도가 우수하였다. 또 효소제, 발효개선제 및 살균제의 첨가에 따른 배술의 화학적 특성을 조사한 결과, 각종 첨가제를 첨가함으로써 무 첨가구에 비하여 pH값이 낮아졌으며 산도는 ammonium phosphate 첨가구가 가장 높았다. 그러나 발효 4일 이후 산도의 변화는 거의 나타나지 않았다. 효소제, 발효개선제, 살균제를 첨가하여 담금한 술의 당도를 측정한 결과 K₂S₂O? 350ppm 첨가구가 가장 빠르게 당도가 감소하였으며 무 첨가구, ammonium phosphate, hemicellulase, pectinase, K₂S₂O? 175ppm순으로 나타났다. 6개의 실험구 모두 발효 과정 중 당도의 감소 속도는 큰 차이 없이 꾸준히 감소하였으며 발효 7일 이후 당도의 감소변화는 거의 없었다. 최종 당도는 9.5~9.8°Brix로 큰 차이는 나타나지 않았다. 에탄올 함량변화는 모든 실험구에서 발효 개시 7일 후 11~12.4%의 에탄올을 생성하였으며 ammonium phosphate을 첨가한 구가 12.4%로 알코올 생성속도가 가장 빨랐고 hemicellulase 첨가구는 전반적으로 알코올 생성속도가 늦었다. 메탄올 함량은 무 첨가구 및 K₂S₂O? 첨가구는 0.05%정도의 함량으로 거의 미비하게 검출되었으며 hemicellulase 및 pectinase 첨가구에서는 0.5%이상의 함량으로 다소 높은 함량을 보여주었다. For increasing the consumption of pear, the pear wines were made by using eight different kinds of yeast. The chemical properties, such as pH, acidity, ethanol and sugar contents, and the consumer acceptance of various pear wines were analyzed. In analysis result of chemical properties, the value of pH was decreased and the acidity was increased until few days, and then retained during fermentation. The ethanol content was increased and the sugar content was decreased during fermentation. The pear wine brewed by B yeast (Lalnin, Saccharomyces cerevisiae) among eight different kinds of yeast had the highest content of ethanol, also this wine was represented the most consumer acceptance by the panels who consist of two age groups such as 20's to 30's and 50's to 60's. Therefore, we chose the yeast B for analyzing the effect of additives during fermentation. As the additives, the K₂S₂O? and ammonium phosphate as the disinfectant and hemicellulase and pectinase as fermenting conditioner were added into the pear wine brewed by yeast B. When additives are added, the chemical properties were the same as followed. Te values of pH was lower than when additives were not added(control). The acidity was he highest when ammonium phosphate was added, but the acidity was not changed after 4 day fermentation. Sugar contents when added K₂S₂O? 350ppm was shown the fastest deceasing, and it was orderly decreased as control, ammonium phosphate, hemicellulase, pectinase, and K₂S₂O? 175ppm. The decreasing rate of sugar content of these 6 test groups during fermentation gradually decreased without a big changes and the after 7 day fermentation, sugar contents were seldom decreased and the final sugar content was 9.5~9.8°Brix. In terms of change of the content of ethanol, all test groups generated 11~12.4% ethanol after 7 day fermentation. The group where ammonium phosphate was added generated 12.4% alcohol, which is the fastest speed and the group, which hemicellulase additive was added, showed generally slow alcohol generation rate. In terms of ethanol contents, the non-additive group and K₂S₂O? additive group showed 0.05%, which is very low, and hemicellulase and pectinase additive group is more than 0.5% which is rather high.