동아시아의 한역(漢譯) 세계지리지(世界地理志) 수용 방식 -조선과 일본에서의 별본(別本) 곤여외기(坤輿外紀) 와 「칠기도설(七奇圖說)」의 독서를 중심으로-

박혜민 한일관계사학회 2023 한일관계사연구 Vol.81 No.-

This thesis examined the process of contents analysis of the new Kunyu waiji edition and extract of the Seven Wonders of the World with reference to Yu Chu xinzhi-a series of collectanea-clarified the process accepted Western Geography in East Asia. Jesuit missionaries wrote Zhifang waiji and Kunyu tushuo to evangelize the Chinese to Catholicism. They wanted the political, social, and cultural superiority of Catholic countries to be demonstrated to the Chinese through World Geography Record. In Joseon, intellectuals from the Sŏngho school tried to respond academically to Western geography by reading and discussing the natural geography part of Kunyu tushuo. However, this academic trend was limited to those living around Seoul among Sŏngho School and was not supported by other intellectuals. In contrast, the difference between Kunyu tushuo and other books by Jesuit missionaries is that they were not read in their original format but were distributed as new editions or excerpts. Kunyu waiji is a recently edited book and Illustrated the Seven Wonders of the World in Yu Chu xinzhi is an extract and fragment of a particular subject from Kunyu tushuo. Originally, Kunyu tushuo was organized according to the classification system of Western geography and was written to promote the excellence of Western civilization; but those two books were edited and extracted regardless of this Western academic context. Many people in East Asia liked these two books more than Kunyu tushuo, demonstrating that they understood Western geography as the genre of chuanqi傳奇-tales of strange events-rather than an academic approach. This study is meaningful in that it reveals specific aspects of the spread of Western geography by Jesuit missionaries and the acceptance of East Asian intellectuals in the 17th and 18th centuries.

IEC 규정 노출지수를 활용한 디지털 방사선 영상시스템에서의 영상 수용체간 특성평가 (Ⅰ)

박혜민,윤용수,노영훈,김성준,나찬영,한태호,김정수,정회원,김정민 대한방사선과학회 2019 방사선기술과학 Vol.42 No.4

The International Electrotechnical Commission (IEC) has regulated the definition and requirements of the exposure index (EI). In this study, we calculated the EI of several image receptors in digital radiography system of two different manufacturers according to the method as per IEC, and evaluated the relationship with incident air kerma. To calculate t he E I, w e obtained the characteristics curve of e ach i mage receptor b y increasing t he i ncident air kerma at R QA 3, 5, 7 and 9, respectively. As a result, there was no significant difference in the EI values between different image receptors of the same manufacturer, but EI values of different manufacturer was different despite the same air kerma was incident. Therefore, understanding the characteristics of the digital radiography systems is important in order to use EI as a tool for measuring and managing the radiation dose.

부들 화분 혈전 용해효소의 정제와 특성

박혜민,구자형,오만진,Park, Hae-Min,Gu, Ja-Hyeong,Oh, Man-Jin 충남대학교 농업과학연구소 2009 Korean Journal of Agricultural Science Vol.36 No.1

When the cattail pollen was identified by using fibrinolytic agents, we found that the fibrinolytic activity was controlled by an enzyme. Therefore, for determining the fibrinolytic activity of cattail pollen, the fibrinolytic enzyme in cattail pollen was purified by gel filtration using DEAE-cellulose, Sephadex G-150 and HPLC. Also, its purity was certified by polyacrylamide gel electrophoresis, and its physico-chemical properties, such as pH and temperature stabilities and effects of metal, inhibitors and substrates, were examined. The specific activity, purification fold, and molecular weight of the enzyme were 38U/mg, 86.4,and 75kDa, respectively. The optimum pH for the purified enzyme was at 4.0 and it was stable at pH 4.0-6.0. The optimum temperature was $55^{\circ}C$ and it was stable at $30-60^{\circ}C$. But the enzyme began to be inactivated at $70^{\circ}C$ and its activity was totally lost at temperatures above $80^{\circ}C$. As for substrate specificity, the enzyme was most effective in dissolving fibrin, followed by whole casein, ${\kappa}$-casein, ${\alpha}$-casein, ${\beta}$-casein, and BSA. With casein as the substrate, Km value was found to be 0.44mM and the enzyme showed a high affinity for casein. As for the metal ions affecting enzyme activity, $K^+$, $Na^+$, and $Mg^{2+}$ had no effect on enzyme reaction while $Zn^{2+}$ and $Fe^{2+}$ showed potent inhibitory activity. Judging from the fact that the purified enzyme was also strongly inhibited by PMSF, iodoacetic acid, and SDA, it assumed to be a serine protease.

신고배(Pyrus pyrifolia Nakai)를 이용한 배술 제조 과정 중 성분 변화

박혜민,이가순,홍종숙,오만진,Park, Hae-Min,Lee, Ka-Soon,Hong, Jong-Sook,Oh, Man-Jin 충남대학교 농업과학연구소 2009 Korean Journal of Agricultural Science Vol.36 No.2

For increasing the consumption of pear, the pear wines were made by using eight different kinds of yeast. The chemical properties, such as pH, acidity, ethanol and sugar contents, and the consumer acceptance of various pear wines were analyzed. In analysis result of chemical properties, the value of pH was decreased and the acidity was increased until few days, and then retained during fermentation. The ethanol content was increased and the sugar content was decreased during fermentation. The pear wine brewed by B yeast (Lalnin, Saccharomyces cerevisiae) among eight different kinds of yeast had the highest content of ethanol, also this wine was represented the most consumer acceptance by the panels who consist of two age groups such as 20's to 30's and 50's to 60's. Therefore, we chose the yeast B for analyzing the effect of additives during fermentation. As the additives, the $K_2S_2O_5$ and ammonium phosphate as the disinfectant and hemicellulase and pectinase as fermenting conditioner were added into the pear wine brewed by yeast B. When additives are added, the chemical properties were the same as followed. Te values of pH was lower than when additives were not added(control). The acidity was he highest when ammonium phosphate was added, but the acidity was not changed after 4 day fermentation. Sugar contents when added $K_2S_2O_5$ 350ppm was shown the fastest deceasing, and it was orderly decreased as control, ammonium phosphate, hemicellulase, pectinase, and $K_2S_2O_5$ 175ppm. The decreasing rate of sugar content of these 6 test groups during fermentation gradually decreased without a big changes and the after 7 day fermentation, sugar contents were seldom decreased and the final sugar content was $9.5{\sim}9.8^{\circ}Brix$. In terms of change of the content of ethanol, all test groups generated 11~12.4% ethanol after 7 day fermentation. The group where ammonium phosphate was added generated 12.4% alcohol, which is the fastest speed and the group, which hemicellulase additive was added, showed generally slow alcohol generation rate. In terms of ethanol contents, the non-additive group and $K_2S_2O_5$ additive group showed 0.05%, which is very low, and hemicellulase and pectinase additive group is more than 0.5% which is rather high.

마늘 잼의 저장과정 중 성상변화

박혜민,곽효순,김소희,문미아,오만진,Park, Hye-Min,Kwak, Hyo-Soon,Kim, So-Hee,Moon, Mi-A,Oh, Man-Jin 충남대학교 농업과학연구소 2008 Korean Journal of Agricultural Science Vol.35 No.2

In order to make a functional jam containing garlic, sugar, acid and pectin were mixed with garlic and concentrated by heating the mixture under atmosphere or vacuum conditions. And changes of some physico-chemical properties of the garlic jam(i.e., color, textural properties, vitamin C) were investigated during storage at $30^{\circ}C$. It was found that lightness(L) was higher in sample of vacuum concentration than that in atmosphere concentration and redness(a) and yellowness(b) were higher in sample of atmosphere concentration. During the storage lightness was found to decrease for all samples with more drastic decrease in sample of atmosphere concentration where browning was more severely observed after 8 weeks of storage. In terms of textural properties, hardness, chewiness and gumminess were higher in sample of atmosphere concentration than that in vacuum concentration. And springiness and cohesiveness were higher in sample of vacuum concentration. Although sensory score for garlic jam found to be lower than that for the existing strawberry jam, the present garlic jam might have high marketability if considering its physiological value.

300 MWe급 수소/천연가스 혼소 복합화력의 공정해석

박혜민,박성호,류주열,권도현 한국에너지학회 2022 한국에너지공학회 학술발표회 Vol.2022 No.4

식수대용차 재료의 비의도적 유해물질 오염도 조사연구

박혜민,김애경,양용식,최수연,서두리,조배식,서계원,김진희 한국식품위생안전성학회 2020 한국식품위생안전성학회지 Vol.35 No.2

2018년 10월부터 2019년 10월까지 광주지역의 대형마트(50건), 재래시장(25건) 및 온라인(50건)에서 구입한 보리차, 옥수수차, 결명자차, 둥글레차, 옥수수수염차 등 침출차 총 125건을 대상으로 중금속, 벤조피렌, 곰팡이독소 함량 조사를 통해 오염실태를 평가하였다. 중금속 중 As, Cd, Pb 함량을 검사하였으며, benzopyrene은 발암물질로 분류된 benzo(a)pyrene의 함량을 조사하였다. 그리고 곰팡이독소는 aflatoxin (AFB1, AFB2, AFG1, AFG2), ochratoxin A (OTA), fumonisin (FUB1, FUB2), zearalenone (ZON)의 함량을 검사하였다. 「식품공전」에 제시된 침출차의 규격과 비교해 보았을 때 중금속 함량은 기준이 설정된 범위(Pb 5.0 mg/kg 이하) 내에서 검출되어 모두 적합하였고, benzo(a)pyrene은 125건 중 16건의 시료에서 12.8%의 검출률을 나타내었으며, 곰팡이독소는 125건 중 29건의 시료에서 23.2%의 검출률을 나타내었다. 하지만 현재 우리 나라 「식품공전」에서는 침출차의 벤조피렌, 곰팡이독소 기준규격이 정해져있지 않아 이에 대한 안전성 여부는 확인하기 어려웠다. This study was conducted to survey levels of heavy metals, benzopyrene and mycotoxins in teas purchased from online markets, supermarkets, and traditional markets in Gwangju, Korea. We examined the arsenic, cadmium and lead content in heavy metals. We also tested for benzo(a)pyrene, which is classified as a carcinogen. In addition, we tested for the mycotoxins aflatoxin (AFB1, AFB2, AFG1,AFG2), ochratoxin A (OTA), fumonisin (FUB1, FUB2), and zearalenone (ZON). According to our results, heavy metals were detected within the allowable range (below 5.0 mg/kg for lead) and all samples met with the standards for tea as presented in the Korean Food Code. The Benzo(a)pyrene showed a detection rate of 12.8% in 16 of 125 samples and mycotoxins showed 23.2% in 29 of 125 samples. However, safe levels regarding benzo(a)pyrene and mycotoxin in tea were not ascertainable since the standards are not set in the Korean Food Code.

Antagonic Effects of Dexamethasone on FK506-induced Antitumor Effects in Hep3B Cells

박혜민,이세진,김선영,고현규,전설희,김상진,강형섭,김진상 한국임상수의학회 2011 한국임상수의학회지 Vol.28 No.6

FK506 is a widespread immunosuppressive drug after liver transplantion in patients with advanced-stage hepatocellular carcinoma. Dexamethasone is frequently used as co-treatment in cytotoxic cancer therapy, e.g. to prevent nausea, to protect normal tissue or for other reasons. Our aim was to investigate antitumor effects of FK506 in Hep3B cells, one of differentiated human hepatocellular carcinoma cell lines and inhibitory effects of dexamethsone on FK506-induced antitumor effects. Cell injury was evaluated by biochemical assays as cell viability, lactate dehydrogenase (LDH)and reactive oxygen species (ROS) in Hep3B cells. Intracellular calcium concentration ([Ca^(2+)]i) and the level of activation of the c-Jun-N-terminal kinase (JNK) and the Bax protein in cultured Hep3B cells was measured. Exposure of 0.1 μM FK506 to Hep3B cells led to cell death accompanied by a decrease in cell viability and an increase in LDH, ROS and [Ca^(2+)]i. FK506 induced an increase in activity of Bax and JNK protein but inhibited the activity of Bcl-2 protein. Treatment of dexamethsone, per se, had no effects on cell viability, LDH and ROS. However, co-treatment of FK506 and dexamethasone diminished the FK506-induced LDH release, ROS generation and JNK activation. These results demonstrate that FK506 has antitumor effect in Hep3B cells but the combination of FK506 and dexamethasone antagonizes the FK506-induced antitumor effects.

[Portfolio] 라라랜드 / HACA! / 생태계 멸종동물, 교육계 멸종과목 다 함께 지켜요! / 하니정의 달콤한 여행

박혜민,김진솔,권영옥,김지현 아에이오우디자인(주) 2016 (월간)아이 러브 캐릭터 = I Love character Vol.2016 No.3

습식 저장시설 내 사용후핵연료 연소도 측정을 위한 감마선/중성자 검출기 개발

박혜민,김태영,이인호,장대헌,송양수,이운장,함철민 (사)한국방사선산업학회 2024 방사선산업학회지 Vol.18 No.3

For the safe management and disposal of spent fuel, it is essential to accurately determine the quan tities of nuclides present within the spent fuel. In this study, a Gamma/Neutron detection system was developed asa part of basic research to measure the burnup profile of spent fuel, and a performance was evaluated using majornuclides. The prototype of the Gamma/Neutron detection system consisted of a CZT sensor and a 3He chamber. Forquantitative evaluation, studies were conducted using calibrated 137Cs, 134Cs, 154Eu and 252Cf sources. In the perfor mance evaluation, a field applicability was verified by analyzing the detection characteristics according to the nuclide.