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교통사고 후 신체 손상 환자의 외상후 스트레스장애에 대한 연구
강영수,김동인,이선미,김 임,김태형,은헌정 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.4
연구 목적 : 임상가를 위한 외상후스트레스장애 척도를 이용하여 교통 사고 후 신체 손상 환자의 외상후스트레스장애의 발병률을 알아보고, 사회인구학적 변인들, 손상 심각도, 불안, 우울과 외상후스트레스장애와의 상호관련성을 고찰하고자 하였다. 방 법 : 104명의 교통사고 환자들을 대상으로 , 자기 보고형인 사고 후 정신 건강에 관한 설문지와 외상후스트레스장애를 진단하기 위해서 임상가를 위한 외상후스트레스장애 척도를 이용하여 면담을 실시하였으며, 손상 심각도 척도를 이용하여 신체 손상의 정도를 측정하였다. 결 과 : 외상후스트레스장애의 발병률은 61.5%이었으며, 사회인구학적 변인들과 손상 심각도 점수에서는 외상후스트레스장애군과 비 외상후스트레스장애군이 유의한 차이를 나타내지 않았다. 그러나 외상후스트레스장애 군에 속한 사람들이 사고 당시에 사망자나 부상자를 목격한 경우가 의미있게 많았고(χ²=8.48, p<0.05). Beck의 우울점수가 외상후스트레스장애군에서 유의한 증가를 보였다.(t=5.03, p<0.05). 결 론 : 교통사고 후 외상후스트레스장애의 발병률은 매우 높았고, 두 집단 모두가 정상인 보다 훨씬 더 높은 불안과 우울을 보고하고 있다. 이와 함께 연구 결과는 상황에서 사망자와 부상자의 목격시 외상후스트레스장애로 발병하게 하는 위험 요인 중 하나 일 수 있다. Objectives : the authors attempted to estimate the incidence of posttraumatic stress disorder (PTSD) and the differences of sociodemographical feature, injury severity, depression and anxiety between PTSD and non-PTSD groups after motor vehicle accident. Methods : The subjects were 104 patients who had undergone motor vehicle accidents, and been hospitalized to orthopedic surgery hospitals. We administered them clinician-administered PTSD scale(CAPS) for diagnosing PTSD, injury severity scale(ISS) for identifying their physical injury, self-reported questionnaire made to identify socioepidemographic data, Beck Depression Inventory(BDI) for measuring depression, and State Trait Anxiety Inventory Ⅰ,Ⅱ(STAI-Ⅰ,Ⅱ) for measuring anxiety. Results : The incidence of PTSD in subjects was 61.5%. Most of sociodemographic factors were not different between PTSD and non-PTSD groups. Only there were significant differences between PTSD group and non-PTSD group on the cases that observed the dead or the wounded at the scene of motor vehicle accident(χ²=8.478, p<0.05) and BDI(t=5.03, p<0.05). Conclusion : These results indicate that prevalence of PTSD is higher after motor vehicle accident and both of the two groups report much higher depression and anxiety than normal population. In addition, the results of this study show that the observation of dead or wounded at accident situation can be one of risk factors to precipitate PTSD.
김계웅,김민진,옥영수,김학연 한국식생활문화학회 2014 韓國食生活文化學會誌 Vol.29 No.4
This survey was conducted to investigate consumer preferences for branded and imported pork, including favorite cooking styles. Data were collected from a total of 252 consumers and analyzed. The results are summarized as follows. Consumers of branded pork showed a moderate preference「moderate」(54%). There was no significant difference in consumer preference for branded pork according to educational level or living area. However, there was a significant difference according to yearly income (p<0.05). Consumers in the high-income group preferred branded pork more than those in the low-income group. Most consumers did not like imported pork (64.6%). There was no significant difference in consumer preference for imported pork according to educational level or living area, whereas there was in the yearly income group (p<0.05). Whereas low-income consumers did not like imported pork, high-income consumers did. The royalty for purchasing of branded pork was shown「3.65」out of 5 points. Whereas there was no significant difference according to educational level, there was for living area and yearly income (p<0.05). Consumers living in large cities or having low income showed high royalty of purchase for branded pork. The royalty for purchase of imported pork was「2.08」out of 5 points. Significant differences for purchase royalty of imported pork were observed according to educational level, living area, and yearly income group (p<0.05). Consumers responded that they liked roasted pork (47.6%). Secondly, consumers liked stew (16.7%). There were no significant differences among various cooking styles in any of the groups.
두경부 편평 세포암의 원발 병소와 전이 경부 림프절에서 Matrix Metalloproteinase-9와 Basic Fibroblast Growth Factor의 발현
노영수(Young Soo Rho),황준식(Joon Sik Hwang),김진(Jin Kim),김진환(Jin Hwan Kim),조성진(Sung Jin Cho),신형식(Hyung Sik Shin) 대한두경부종양학회 2004 대한두경부 종양학회지 Vol.20 No.1
Objectives: Cancer lethality is usually the result of local invasion and metastasis of neoplastic cell from the primary tumor. Because of their ability to degrade extracellular matrix components, matrix metalloproteinases (MMPs) and basic fibroblast growth factor (bFGF) have been implicated in the breakdown of basement membrane and underlying stroma, thereby facilitating tumor growth and invasion. It has been well established that MMPs and bFGF expression correlate with cervical lymph node metastasis, but studies on expression in the metastatic cervical lymph node itself are not enough. We have analyzed matrix metalloproteinases (MMPs) and basic fibroblast growth factor (bFGF) in squamous cell carcinoma of the head and neck and metastatic cervical lymph node, and evaluated their relationship and clinicophathologic significance. Material and Methods: 20 cases of squamous cell carcinoma of the head and neck were entered on the study of immunohistochemical stains for MMP-9 and bFGF in the obtained tissue from primary tumor and metastatic cervical lymph node. We analyzed the relationship between MMP-9, bFGF expression of the primary tumor and metastatic node with age, sex, T-stage, N-stage, histologic grade, pathologic stage and disease free survival. Results: Expression of MMP-9 and bFGF in cancer cell and metastatic lymph node was higher than that in normal cell and lymph node. According to histologic differentiation, expression of MMP-9 of the metastatic cervical lymph node was higher than primary tumor. Considering to other clinicopathologic factor, no statistical significance was seen in MMP-9 and bFGF. Conclusion: We found that expression of MMP-9 is higher in the metastatic lymph node than primary tumor in the poorly differentiated squamous cell carcinoma. But we don't find out the statistical significance in relation between bFGF and clinical factors. So we guess that some different mechanism of MMP-9 and bFGF in Head & Neck squamous cell carcinoma exist. Further studies will be necessary to establish their pathogenesis in the Head and Neck cancer.