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박영관,조원현,박성대,김현철,박성배,김천일 계명대학교 醫科大學 外科學敎室同門會 1990 남경 박영관 교수 정년퇴임기념 논문집 Vol.S No.-
Various factors that affect the outcome of renal allografts have been studied and analyzed by many authors. In order to compare the results of renal transplantation, we followed up and analyzed the renal transplantation patients which have been performed in our hospital from 1982 through 1987. The overall l and 2 year patient survivals were 91.9% and graft survivals were 87.2%, 75.9%respectively. 100% of 1 year graft survival was observed in 4 cases of HLA identical related living donor and 84.2% for haploidentical group including 2 antigens sharing group in non-related living donor. Their 2 year graft survivals were 100% for full matched group and 78.9% for haploidentical group. In the case of transplantation between siblings, both 1 and 2 year graft survivals were 72.6% and showed no significant difference compare with the group between parent donor and child recipient. Among 55 total cases, 43 cases were done pretransplant transfusion including DST. Compare with66.7% 1 and 2 year graft survivals of non-transfused group, the survivals of transfused group was 89. 5% at 1 year and 75.9% at 2 year(p<0.05). Better graft survivals were observed in the group more than 11 units transfusion before transplantation. According to ischemic time which was defined as duration between the time of clamp of renal artery from donor and revascularization in recipient, 1 year and 2 year graft survival of less than 60minutes grωp(n = 35) were 93.2% and 77.0% but 64.4 % at 1 and 2 year in over 60 minutes group. First urine after finishing vascular anastomosis in recipient was noticed within 5 minutes in 40 cases and their 1 and 2 year graft survivals were 91.5% and 73.9% and these were comparable with the results of the. group that took more than 5 minutes (61.9% at 1 and 2 year). Graft survivals according to other factorsinc1uding donor and recipient age, sex and blood type were also analyzed but showed no significant differences.