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      • SCOPUSKCI등재

        뽕잎추출물이 Zucker Rat의 체지방 축적에 미치는 효과

        김순경(Soon-Kyung Kim),선여(Sun-Yeou Kim),휘준(Hwi-Jun Kim),애정(Ae-Jung Kim) 한국식품영양과학회 2001 한국식품영양과학회지 Vol.30 No.3

        뽕잎의 체지방 축적 억제 효과를 알아보기 위하여 유전적으로 비만이 유도된 obese fa/fa male Zucker rat에 뽕잎 추출물을 경구투여하였다. 그 후 체중의 변화, 사료섭취량, 혈장 중 leptin, insulin, 중성지질과 콜레스테롤 함량과 간, brown adipose tissue 등의 중량을 측정하였다. 3주 동안 뽕잎추출물을 250 mg/kg of body weight의 농도로 처리한 뽕잎투여군의 경우 141%의 체중증가를 보였고, 대조군은 148%의 체중증가를 보여 뽕잎투여군의 체중증가가 7%정도 낮았으나 유의적인 차이는 없었다. 1일당 체중증가량은 대조군 5.18 g, 뽕잎투여군은 4.15 g으로 뽕잎투여군이 대조군에 비해 낮게 나타났다. 1일 사료섭취량은 각각 25.69 g, 25.61 g으로 두군간의 사료섭취량에 차이는 없었다. 사료이용효율은 대조군과 뽕잎투여군간에 유의적인 차이는 없었으나 대조군 0.205, 뽕잎투여군 0.185로 시료를 투여함에 따라 사료이용효율이 저하되는 경향이었다. Leptin과 insulin 함량은 대조군과 뽕잎투여군에서 유의적인 차이가 없었으나, leptin과 insulin 함량은 뽕잎투여군에서 각각 18%, 0.5% 높게 나타났다. 총 콜레스테롤과 중성지질함량은 뽕잎투여군이 대조군에 비하여 유의적으로(p<0.01) 낮게 나타났다. 총 콜레스테롤 중 HDL-콜레스테롤이 차지하는 비율은 뽕잎투여군(대조군의 158%)이 유의적으로(p<0.05) 더 높게 나타났다. 대조군과 뽕잎투여군간의 전체 체중당 간, brown adipose tissue 중량의 비율은 유의적인 차이는 나타나지 않았다. 이상의 결과에서 뽕잎 추출물을 obese fa/fa male Zucker rat에 체중당 250 mg의 용량으로 3주간 경구투여함으로써 대조군에 비하여 10% 정도의 체중감소를 보였고 사료섭취효율의 저하 효과도 관찰되었다. 또한 leptin의 함량은 증가되었고, 중성지질과 총 콜레스테롤은 유의적으로 감소되었고, 총 콜레스테롤 중 HDL-콜레스테롤이 차지하는 비가 높아짐을 확인할 수 있었다. This study was conducted to investigate whether the obesity of obese fa/fa male Zucker rats can be ameliorated by mulberry leaves. There was no significant difference between mulberry treatment group and control group in body weight gain and food efficiency ratio. It also showed decreases of plasma triglyceride and totalcholesterol concentration compared to the control group. But there was no change in plasma leptin concentration between the control and mulberry treatment groups. These results suggest that mulberry leaves reduce serum lipid levels, but do not effect the plasma leptin concentration.

      • Inmold 사출 장치의 개발을 위한 사출품의 성형해석에 관한 연구

        김순경(Soon-Kyung Kim),박정호(Jeong-Ho Park),태호(Tae-Ho Kim) 한국기계가공학회 2008 한국기계가공학회 춘추계학술대회 논문집 Vol.2008 No.-

        In the case of Inmold injection, It is a device which conducts injection and painting. In order to design it is important composition of devices to accurate feed of film and process of analysis which is a flow aspect of resin occurred in mold. it used program of plastic injection flow analysis in order to a flow aspect of resin. It might be used shape crystallization of products, design of mold and process of feed device.

      • KCI등재

        제라르 드 네르발과 부재의 원본

        김순경 ( Soon Kyung Kim ) 연세대학교 인문학연구원 2015 人文科學 Vol.105 No.-

        This study addresses Nerval’s obsession with resemblance, which continuously haunted hid mind. Many critics have revealed the importance of Nerval’s mental illness in his creative life. Through his writing, Nerval wanted to place a certain distance from his own self, abolish time, and distinguish between appearance and essence; he attempted to access the spiritual universe through reverie and “l’epanchement du songe dans la vie reelle (the outpouring of dreams in real life).” By doing so, he tried to cross the “portes d’ivoire (ivory doors)” and consciously externalize the hallucinatory delirium that overtook him during periods of manic excitement, as he did not believe in his insanity. The obsession with the image of a mother who disappeared precociously takes on considerable importance in Nerval’s life. The attempt to resuscitate this love deja perdu (already lost) through figures, both imaginary and real, bears witness to the solitude of his narcissistic world; the Nervalian object of desire is reduced to an ideal, life-saving image. Nerval’s various feminine figures are inseparable and repeat a supreme mode, ‘l’Unique (the one and only)’. The quest for l’Unique comes from the feeling of abandonment connected to the premature disappearance of his mother as well as the unfortunate love Nerval carried for the singer Jenny Colon, whom he excessively idealized. Nerval never stops looking for this mother, who was never present except in these substitutive representations, the resemblances of resemblances of appearances. The Nervalian desire is linked in essence to an image, not to the real object of his love. The more the image of the female is reduced to a sublime idea, and the more its absence is represented, the better it coincides with “l’amour des formes vagues, (...) des fantomes metaphysiques (the love of vagus forms, (...) metaphysical phantoms) so dear to Nerval. Nerval attempts to assemble all his feminine figures in the hope of finding ‘l’Unique’: his work is a true syncretism studded with the diverse incarnations of ‘l’Unique’. He creates a real woman in the form of a mythological and deified figure; Adrienne crowned with laurels comparable to Dante’s Beatrice “qui sourit au poete errant sur la lisiere des saintes demeures (who smiles at the poet wandering on the border of holy dwellings),” makes her appearance again in an allegorical representation of the Abbey of Chaalis. Adriennce bathed in angelic light is a spiritualized image and a mediator. With the death of Adriennce at the end, “l’original eblouissant (the splendid original)” becomes nothing more than a copy of copies: love for his, thus, is always “deja perdu”. He glides from one image to another in his successive metamorphoses to find l’Unique, but each image, always on the run, is only a copy of “l’original de l’absence(the original of the absence)”, of his entirely sacred mother; the repetition does nothing but emphasize “la non-existence(the non-existence)”. The feminine phantoms torment Nerval as much as they appeal to him; “C’est la mort-ou la Morte,,, O delice! o tourment! (It is death-or the dead... Oh delight! Oh torment!)”

      • SCOPUSKCI등재
      • KCI등재
      • 비타민 C의 수종(數種) 암 세포 증식 억제 효과에 관한 연구

        김순경,황우익,Kim, Soon-Kyung,Hwang, Woo-Ik 생화학분자생물학회 1981 한국생화학회지 Vol.14 No.4

        시험관 및 생체 내에서 암 세포 증식에 미치는 비타민 C의 영향을 관찰하기 위하여 20g 내외의 Swiss mice 80마리를 대상으로하여 비타민 C를 체중 1g 당 1회 0.29mg, 0.39mg, 0.58mg, 1.16mg 씩 10회 투여한 4개군과 대조군 등 5개 군으로 나누어 사육하면서 생존기간, 복수로 인한 체중 증가, 암 세포수의 변동 등을 비교 관찰하여 다음과 같은 결과를 얻었다. 1. 시험관 내에서 P 388과 L 1210 세포의 증식은 비타민 C의 투여량에 따라 비례적으로 억제되었다. 2. Sarcoma 180 세포를 주사한 동물의 생존기간은 비타민 C 투여군이 대조군에 비하여 월등히 연장되었으며, 그 가운데 체중 1g 당 1회 비타민 C 0.58mg 투여군이 연장율이 가장 높았다. 그러나 체중 1g 당 1회 비타민 C 1.16mg 투여군은 다른 농도의 비타민 C 투여군에 비하여 생존기간 연장율이 낮게 나다났다. 3. 복수로 인한 체중의 변동은 대조군과 각 투여량 별 비타민 C 투여군이 거의 같은 비율로로 증가되었다. 4. 비타민 C 투여에 의하여 시험관 내에서 배양된 P 388 및 L 1210 세포의 증식은 대조군에 비하여 억제되었으나 mice 체내에서 배양된 sarcoma 180 세포수에는 큰 영향이 없었다. 이 상의 결과로부터 비타민 C에는 시험관 내 P 388 및 L 1210 세포의 증식을 억제시키는 작용이 있으며 sarcoma 180 세포를 주사한 mice의 수명 연장 효과가 있음을 알 수 있었다. This study was designed to observe the effects of vitamin C administration on the division of P 388 and L 1210 cells in vitro and the survival time of the mice inoculate with sarcoma 180 cells. The cancer cells, P 388 and L 1210, were cultured in vitro by the method of Fischer and Sartorelli, and the growth rate and dose-response of the both cells in the absence or in the presence of the various amounts (15 to 80 ${\mu}g/ml$) of vitamin C were compared. The male Swiss mice (80 heads), weighing about 20 g, were inoculated with the sarcoma 180 cells (1,000 cells), and then divided into seven groups (two are control groups ; I for comparison of survival time, II for sacrificed, and six are vitamin C treated groups, 0.29 to 1.16 mg/g once a day). For the survival time, the cell numbers in the ascites and the body weight change were determined during all experimental term. The results obtained are summarized as follows : 1. The division of P 388 and L 1210 cells in vitro were gradually inhibited in proportion to increment of the concentration of the vitamin C added. 2. The survival times of the mice inoculate with the sarcoma 180 cells were significantly extended by administration of vitamin C compared with the control, especially the effects were remarkable in 0.58 mg of vitamin C administered group. 3. The increase of the body weight caused by ascites, in each vitamin C administered groups were shown similar tendency to the central. 4. The numbers of the P 388 and L 1210 cells in vitro were decreased by the administration of vitamin C, but that of the sarcoma 180 cells in viva were not shown significant change. From the above results it was found that vitamin C has the inhibitory activity on the division of the leukemic cells (P 388 and L 1210) in vitro and extends survival time of mice inoculated with sarcoma 180 cells.

      • KCI등재
      • SCOPUSKCI등재
      • KCI등재

        복합운동프로그램이 경증치매여성노인의 일상생활활동 및 기능적 체력에 미치는 영향

        김순경(Soon Kyung Kim),태운(Tae Un Kim),임춘규(Chun Kyu Lim) 한국사회체육학회 2009 한국사회체육학회지 Vol.0 No.38

        This study is to know that combined exercise program impacts on cognitive function of elderly women with mild dementia and Activities of Daily living(ADL) and Functional fitness. It was conducted from september to december 2008. The exercise program was conducted for the 14(EG: 7, CG: 7) people[They were elderly women with mild dementia] who were visiting to the dementia center which located in Busan B Women`s University for 12 weeks(2 times a week, 1 time 35-40 minutes). The change of ADL in this study improved statistically meaningfully pre movement(EG: 14.14±1.07pt, CG; 13.57±0.98pt) and post exercise(EG; 12.71±0.05pt, CG; 13.71±1.11pt). There was an interaction effect between group and period according to the factor, showing the effect of exercise. we had measurements following these. The lower leg muscular strength and muscle endurance measurements pre exercise(EG: 11.00±3.42, CG; 12.86±1.35) and post exercise(EG; 14.14±2.34, CG; 12.43±1.40). The upper leg muscular strength and muscle endurance measurements pre movent(EG; 13.71±1.CG, CG; 14.86±1.77) and post exercise(EG; 17.07±1.73, CG; 14.00±1.63). The lower leg muscular Flexibility measurements pre movement(EG; 8.50±3.53, CG; 8.50±3.53) and post exercise(EG; 54±3.86, CG; 7.49±3.55). The upper leg muscular Flexibility measurements pre movement(EG; 8.41±5.46, CG; 7.86±5.87) and post exercise(EG; 4.56±4.66, CG; 19.43±5.72). Agility and movement balance measurements pre movement(EG; 12.63±3.65, CG; 12.57±3.07) and post exercise(EG; 10.74±3.67, CG; 12.59±3.88), Heart and lung endurance measurements pre movement(EG; 49.29±6.40, CG; 57.00±9.85) and post exercise(EG; 71.14±5.46, CG; 54.29±6.58). There was an interaction effect between group and period according to the factor, showing the effect of exercise. As above, Measurement of these changes represents improvements in general and has a positive meaning. The result of comparing the changes of functional fitness pre and post rehabilitation exercise for elderly women with mild dementia in B dementia center, was improved statistically significantly.

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