타액선 다형성 선종에서 Glycosaminoglycan의 발현

김성주,김철환,김경욱,Kim, Seong-Joo,Kim, Chul-Hwan,Kim, Kyung-Wook 대한악안면성형재건외과학회 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.1

Pleomorphic adenoma is the most common benign tumor in salivary glands, and occurred in frequency of 60% in parotid gland tumors, and 50% in submandibular gland tumors, and 25% in sublingual gland tumors. Histopathologically, pleomorphic adenoma is composed of epithelial cells and mesenchymal tissues, and called 'mixed tumor' because of morphological divergency. The cell structures of luminal area are composed of polyhedral and cuboidal secretory epithelial cells and modified myoepithelial cells around it, and mesenchymal tissue is composed of some myoepithelial cells and stromal tissue. In stromal tissue, myxoid change, chondroid change, or hyalinization can be seen even if bone tissue. In many studies, tumor cells of pleomorphic adenoma containing modified myoepithelial cell participate in synthesis of glycosaminoglycans. In this study, tissue sample of pleomorphic adenoma of human salivary gland were obtained from 20 surgical specimens, and all specimens were routinely fixed in 10% formalin and embedded. Serial 4-8${\mu}m$ thick sections were cut from paraffin blocks. The histopathologic evaluation was done with light microscopy. And, with immunohistochemical staining, characteristics of glycosaminoglycan were observed. And, for biochemical analysis of glycosaminoglycan, isolation of crude glycosaminoglycan from tumor tissue and immuno-blot analysis were carried out. With transmission electromicroscopy, tumor cells and biologic behavior of pleomorphic adenoma were observed with distribution and expression of glycosaminoglycan in tumor cells, The results were obtained as follows: 1. In immunohistochemical study, chondroitin 4-sulfate is highly postively stained in myxoid stromal tissue, and chondroitin 6-sulfate is highly positively stained in chondroid mesenchymal tissue, both glycosaminoglycans are positively stained in non-luminal cell of ductal area. 2. Dermatan sulfate and keratan sulfate is positively stained in periductal non-luminal tumor cells. 3. In immunohistochemical study, heparan sulfate is weakly stained in luminal cells and non-luminal cells around duct, and chondroid mesenchymal tissue. 4. In transmission electromicroscopic view, the tumor cells are composed of modified myoepithelial cells, and contain many microfilaments and well developed rough endoplasmic reticulum. 5. In Immuno-Blot analysis, the expression of glycosaminoglycans is expressed mostly in chondroitin 6-sulfate and chondroitin 4-sulfate. From the results obtained in this study, tumor cells of pleomorphic adenoma are composed of modified myoepithelial cells, and glycosaminoglycans of chondroitin 4-sulfate and chondroitin 6-sulfate mostly participate in the development of pleomorphic adenoma, but dermatan sulfate, keratan sulfate and heparan sulfate glycosaminoglycans were expressed variably.

Dicon Interview-김성주 카렛 사장

김성주,Kim, Seong-Ju 한국데이터베이스진흥원 2006 디지털콘텐츠 Vol.1 No.-

중국소비자 조사에서 휴대폰의 원산국 효과에 따른 라이프스타일 실증 연구

김성주,Kim, Seong-Ju 한국데이터정보과학회 2016 한국데이터정보과학회지 Vol.27 No.6

이 논문에서는 중국소비자들을 대상으로 휴대폰의 원산국 효과에 따라 라이프스타일에서 어떤 차이점이 있는지 실증 분석해 보고자 한다. 분석 데이터는 Kim 등 (2006, 2007)에 의해 선행연구 된 바 있다. 그룹 멤버십은 휴대폰의 원산국 효과에 대한 응답을 바탕으로 응답자를 4개 그룹으로 분류하였다. 즉, 4개 그룹은 한국산 휴대폰을 선호하는 그룹 K, 일본산 휴대폰을 선호하는 그룹 J, 미국산 휴대폰을 선호하는 그룹 U, 그리고 중국산 휴대폰을 선호하는 그룹 C이다. 이러한 그룹 멤버십을 바탕으로 일원배치 분산분석과 단계적 판별분석을 이용하여 89개 라이프스타일 변수와 2개 개인정보로 이루어진 학습표본 (training sample)을 4개 그룹으로 분류하였다. 그 결과 한국산 휴대폰을 선호하는 그룹 K는 중국산 휴대폰을 선호하는 그룹 C에 비해 개방적이고, 진보적이고, 적극적이고, 그리고 개성이 강한 것으로 보였다. This paper is an empirical study of chinese consumers' lifestyle by country of origin effect of mobile phone. The data we analyze in this paper was collected and studied in Kim et al. (2006, 2007). We classify the respondents into the four groups according to the responses of country of origin effect of mobile phone. The four groups are group K (preference in made in Korea), group J (preference in made in Japan), group U (preference in made in USA), and group C (preference in made in China). One-way ANOVA and stepwise discriminant analysis are applied to classify the training sample which consists of 89 lifestyle variables and two personnel information. It is observed that group K is more open-minded, out front, aggressive, and self-assertive compared to group C.

직교 기저함수 기반의 혼합 신경회로망 구조

김성주,서재용,조현찬,김성현,김홍태,Kim, Seong-Joo,Seo, Jae-Yong,Cho, Hyun-Chan,Kim, Seong-Hyun,Kim, Hong-Tae 대한전자공학회 2002 電子工學會論文誌-CI (Computer and Information) Vol.39 No.6

웨이블릿 함수의 경우 스케일링 함수에서 비롯되었으며, 스케일과 중심을 결정함으로써 신경회로망의 노드로 구성된다. 본 논문에서는 웨이블릿 함수를 이용하여 망을 구성하는 과정에 스케일링 함수를 은닉층의 노드로 복합 구성한 구조를 제안하고자 한다. 제안한 구조의 특징은 스케일링 함수를 이용하여 대강 근사(rough approximation)를 행한 다음, 웨이블릿 함수를 이용하여 미세 근사(fine approximation)를 행하도록 신경회로망의 은닉층을 복합 구성하는 데 있다. 또한, 복합 신경회로망을 구성하는 과정에서 미세 근사에 필요한 웨이블릿 함수의 개수를 유전 알고리즘을 이용하여 결정하는 초기 구조의 최적화를 도모하고자 한다. The wavelet functions are originated from scaling functions and can be used as activation function in the hidden node of the network by deciding two parameters such as scale and center. In this paper, we would like to propose the mixed structure. When we compose the WNN using wavelet functions, we propose to set a single scale function as a node function together. The properties of the proposed structure is that while one scale function approximates the target function roughly, the other wavelet functions approximate it finely. During the determination of the parameters, the wavelet functions can be determined by the global search algorithm such as genetic algorithm to be suitable for the suggested problem. Finally, we use the back-propagation algorithm in the learning of the weights.

타액선 다형성 선종에서 Glycosaminoglycan의 발현

김성주,김철환,김경욱,Kim, Seong-Joo,Kim, Chul-Hwan,Kim, Kyung-Wook 대한악안면성형재건외과학회 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.2

Pleomorphic adenoma is the most common benign tumor in salivary glands, and occurred in frequency of 60% in parotid gland tumors, and 50% in submandibular gland tumors, and 25% in sublingual gland tumors. Histopathologically, pleomorphic adenoma is composed of epithelial cells and mesenchymal tissues, and called 'mixed tumor' because of morphological divergency. The cell structures of luminal area are composed of polyhedral and cuboidal secretory epithelial cells and modified myoepithelial cells around it, and mesenchymal tissue is composed of some myoepithelial cells and stromal tissue. In stromal tissue, myxoid change, chondroid change, or hyalinization can be seen even if bone tissue. In many studies, tumor cells of pleomorphic adenoma containing modified myoepithelial cell participate in synthesis of glycosaminoglycans. In this study, tissue sample of pleomorphic adenoma of human salivary gland were obtained from 20 surgical specimens, and all specimens were routinely fixed in 10% formalin and embedded. Serial 4-8${\mu}m$ thick sections were cut from paraffin blocks. The histopathologic evaluation was done with light microscopy. And, with immunohistochemical staining, characteristics of glycosaminoglycan were observed. And, for biochemical analysis of glycosaminoglycan, isolation of crude glycosaminoglycan from tumor tissue and immuno-blot analysis were carried out. With transmission electromicroscopy, tumor cells and biologic behavior of pleomorphic adenoma were observed with distribution and expression of glycosaminoglycan in tumor cells, The results were obtained as follows: 1. In immunohistochemical study, chondroitin 4-sulfate is highly postively stained in myxoid stromal tissue, and chondroitin 6-sulfate is highly positively stained in chondroid mesenchymal tissue, both glycosaminoglycans are positively stained in non-luminal cell of ductal area. 2. Dermatan sulfate and keratan sulfate is positively stained in periductal non-luminal tumor cells. 3. In immunohistochemical study, heparan sulfate is weakly stained in luminal cells and non-luminal cells around duct, and chondroid mesenchymal tissue. 4. In transmission electromicroscopic view, the tumor cells are composed of modified myoepithelial cells, and contain many microfilaments and well developed rough endoplasmic reticulum. 5. In Immuno-Blot analysis, the expression of glycosaminoglycans is expressed mostly in chondroitin 6-sulfate and chondroitin 4-sulfate. From the results obtained in this study, tumor cells of pleomorphic adenoma are composed of modified myoepithelial cells, and glycosaminoglycans of chondroitin 4-sulfate and chondroitin 6-sulfate mostly participate in the development of pleomorphic adenoma, but dermatan sulfate, keratan sulfate and heparan sulfate glycosaminoglycans were expressed variably.

응급구조과 학생의 구급차동승실습 만족도에 영향을 미치는 요인

김성주,Kim, Seong-Ju 한국임상보건과학회 2019 한국임상보건과학회지 Vol.7 No.2

Purpose: The purpose of this study was to provide an appropriate direction for effective field practice program by analyzing the influencing factors on satisfaction in ambulance ride practice of paramedic students in Korea. Methods: This study analyzed of 180 paramedic students from 20th to 30th september, 2019. The collected data were analyzed with MedCalc 18.1.0 program. Results: The results of the satisfaction of ambulance riding practice according to the degree of procedure practice are as follows. Satisfaction was high in all groups except the practice time. The lowest satisfaction rate was seen in the category of'There were many cases of applying theories learned at college'within the variable of practice environment(2.82±0.82). The factors affecting the satisfaction of ambulance riding practice were the nurse (β=-0.1472, p=.024) and emergency medical technician(β=-0.3318, p=.002) according to the ambulance worker qualification paramedic, and the practice score (β=0.0048, p<.001). Conclusions: For effective ambulance riding practice, it is necessary to be able to select the practice place where many cases can be experienced, the appropriate selection of the practice leader, and the degree of procedure practice.

베트남 웨이에 동참하자

김성주,Kim, Seong-Ju 한국데이터베이스진흥원 2006 디지털콘텐츠 Vol.5 No.-

문명과 야만의 이분법이 인류평화의 적

김성주,Kim, Seong-Ju 대한출판문화협회 2001 출판저널 Vol.312 No.-

다변량 분산분석을 이용한 포장 재질에 따른 쌀의 신선도 분석

김성주,Kim, Seong-Ju 한국통계학회 2016 응용통계연구 Vol.29 No.7

본 논문에서는 포장 재질에 따라 쌀의 신선도가 어떻게 달라지는지 알아보기 위해 다변량 분산분석을 적용해 보았다. 쌀의 신선도는 쌀의 수분 함량과 식미치로 측정하였다. 포장 재질은 일반 종이와 종이 뒷면에 숯을 코팅한 종이를 비교하였다. 쌀을 보관하는 장소를 블록으로 간주하였다. 쌀의 수분 함량과 식미치를 나타내는 이변량 관측값에 대하여 완전 확률화 블록 설계에 의한 다변량 분산분석을 적용해 본 결과 포장 재질에 따라 유의한 차이를 보였다. 따라서 쌀의 수분 함량과 식미치 각각을 단일변량 관측값으로 간주하고 분산분석을 적용해 보았다. 그 결과 쌀의 수분 함량에 대해서는 포장 재질에 따라 유의한 차이를 보였으나 식미치에 대해서 유의한 차이 관측할 수 없었다. This paper concerns the freshness of rice depending on packing materials using MANOVA. Freshness of rice is measured in terms of moisture content and rice flavor. Ordinary paper and charcoal-coated paper are compared as packing materials. Storing places are considered as a block. The bivariate observations of moisture content and the rice flavor are compared using MANOVA for a completely randomized block design. It is observed that there is a significant difference between ordinary paper and charcoal-coated paper. Therefore we apply ANOVA for moisture content and rice flavor, respectively. Significant differences are observed for the moisture content but not for the rice flavor.

디지털 트윈을 이용한 신 사업 진출

김성주,강명신,Kim, Seong-Ju,Gang, Myeong-Sin 한국건설관리학회 2019 건설관리 : 한국건설관리학회 학회지 Vol.20 No.2