수열 합성 공정 조건이 티탄산 납의 상 형성에 미치는 영향

김경아,김정석,천채일,Kim, Kyoung-A,Kim, Jeong-Seog,Cheon, Chae-Il 한국세라믹학회 2011 한국세라믹학회지 Vol.48 No.1

Lead titanate ($PbTiO_3$) powder was prepared from lead nitrate ($Pb(NO_3)_2$) and titania ($TiO_2$) by hydrothermal route. Phase formation process was investigated by observing the phases formed in various experimental conditions like different KOH concentration, reaction temperature and time. $PbTiO_3$ powder was fabricated when the KOH concentration was 0.8M or higher. An intermediate compound, $PbTi_{0.8}O_{2.6}$, was formed at first by a reaction between PbO and $TiO_2$ and changed into $PbTiO_3$ powder with a perovskite crystal structure. A $PbTiO_3$ phase was formed in a shorter time when a KOH concentration was increased from 0.8M to 8M because a driving force for a $PbTiO_3$ formation was increased due to an increase in a degree of supersaturation. And $TiO_2$ (rutile) and $3PbO{\cdot}H_2O$ were observed at room temperature in a 0.8M KOH solution and $TiO_2$(rutile) and PbO (litharge) in a 8M KOH. A $PbTiO_3$phase was also formed in a shorter time at a higher reaction temperature as a reaction temperature influenced the rates for a dissolution and a precipitation.

단순진폐증에 대한 흉부 고해상 전산화 단층촬영의 진단적 의의

김경아,김지홍,장황신,안형숙,임영,윤임중,Kim, Kyoung-Ah,Kim, Hi-Hong,Chang, Hwang-Sin,Ahn, Hyeong-Sook,Lim, Young,Yun, Im-Goung 대한예방의학회 1996 Journal of Preventive Medicine and Public Health Vol.29 No.3

Early recognition of coalescence in pneumoconiotic lesions is important because such coalescence is associated with the respiratory symptoms and deterioration of lung function. This complicated form of pneumoconiosis also has worse prognosis than does simple pneumoconiosis. High resolution computerized tomography(HRCT) provides significant additional information on the stage of the pneumoconiosis because it easily detects coalescence of nodules and emphysema that may not be apparent on the simple radiograph. The purpose of this study is to clarify the role of HRCT in detection of large opacity and the relationship of change between the coalescence of nodules or emphysema and lung function in dust exposed workers. 1. There was good correlation between the HRCT grade of pneumoconiosis and ILO category of profusion. 5(9.09%) in 55 study population had confluent nodule extending eve, two o, more cuts on HRCT. HRCT could identify the pneumoconiotic nodules which was not found by simple radiogrphy in 6 workers with category 0/0. 2. No significant difference was observed coalescence of nodules and emphysema by dust type. 3. There was no significant difference in pulmonary function according to ILO and HRCT classification. 4. HRCT could detect the significant reduction in $FEV_1,\;FEV_1/FVC$, PEFR, $FEF_{25},\;FEF_{50},\;and\;FEF_{75}$ and remarkable increase in RV and TLC in study persons with emphysema compared with non-emphysema group. 5. Emphysema was found more often in nodules-coalescence group than small opacity group by HRCT. We found that HRCT could easily detect areas of coalescence and complicated emphysema compared to plain chest X-ray. Also our data suggest that it is primarily the degree of emphysema rather than the degree of pneumoconiosis that determines the level of pulmonary function.

PM2.5로 자극한 폐상피세포의 $NF{\kappa}B$ 활성화에 NO의 역할

김경아,남혜윤,문제혁,정진숙,임영,Kim, Kyoung-Ah,Nam, Hae-Yun,Mun, Je-Hyeok,Jeong, Jin-Sook,Lim, Young,Kai, Hirofumi 대한결핵및호흡기학회 2002 Tuberculosis and Respiratory Diseases Vol.52 No.6

연구배경 : PM2.5는 호흡기질환의 악화 및 호흡기 질환에 의한 사망률과 밀접하게 관계가 있다. PM2.5에 의한 호흡기 염증반응의 악화가 그 원인으로 생각되나 염증반응의 조절기전은 확실하지 않다. 본연구에서는 PM2.5에 의한 폐장의 염증반응을 조절하는데 중요한 역할을 하는 전사인자인 $NF{\kappa}B$의 활성화 기전을 알아보아 염증 조절기전에 대한 이해를 높이고자 시도되었다. 방 법 : 폐상피세포주인 A549 세포에서 PM2.5 자극에 의한 $NF{\kappa}B$의 활성화 및 ROS, 그리고 RNS 분비를 관찰 하였다. iNOS 억제제인 L-NIL가 $NF{\kappa}B$ 활성화에 미치는 영향을 관찰하였다. 결 과 : PM2.5는 A549 세포에서 $NF{\kappa}B$의 활성화를 유도 하였다. PM2.5로 A549 세포를 자극시 즉각적인 RNS의 분비는 관찰되었으나 명확한 ROS의 증가는 관찰되지 않았다. RNS 억제제인 L-NIL 처리시 $NF{\kappa}B$ 활성화는 억제되었다. 결 론 : A549 세포에서 PM2.5에 의하여 유도된 즉각적인 $NF{\kappa}B$ 활성화 과정에는 RNS가 중요한 역할을 할 것으로 생각된다. Background : The present study was performed to further improve our understanding of molecular mechanisms involved in the activation of NFkB, a major transcriptional factor involved in the inflammatory response in the lung, by particulate matter in lung epithelial cells with an aerodynamic diameter of less than $2.5{\mu}m$(PM2.5). Materials and Methods : Immediate production of reactive oxygen species (ROS) and nitrogen species (RNS), with the PM2.5 induced expression of inducible nitric oxide synthase (iNOS), $I{\kappa}B$ degradation and $NF{\kappa}B$-dependent transcriptional activity, in 549 cells, were monitored. Addition, we also examined the effect of the iNOS inhibitor, L-N6-(1-iminoethyl) lysine hydrochloride (L-NIL), on the PM2.5-induced $NF{\kappa}B$ activation in A549 cells. Results : The rapid degradation of $I{\kappa}B$ and the increase of transcriptional activity of the $NF{\kappa}B$-dependent promotor were observed in A549 cells exposed to PM2.5. The immediate production of ROS in response to PM2.5 in A549 cells was not clearly detected, although immediate responses were observed in RAW264.7 cells. A 549 cells, cultured in the presence of PM2.5, produced an increase in NO, which was noticeably significant after 15 min of exposure with the expression of iNOS mRNA. The addition of L-NIL, an iNOS inhibitor, significantly inhibited the PM2.5-induced $I{\kappa}B$ degradation and the increase of the $NF{\kappa}B$-dependent transcriptional activity. Conclusion : These results suggest that PM2.5 stimulates the immediate production of RNS, leading to the activation of $NF{\kappa}B$ in the pulmonary epithelium.

원발성 부갑상선항진증에 의한 악골의 다발성 갈색종양

김경아,고광준,Kim, Kyoung-A,Koh, Kwang-Joon 대한영상치의학회 2010 Imaging Science in Dentistry Vol.40 No.3

Brown tumor is usually diagnosed at the terminal stage of hyperparathyroidism. Diagnosis of this tumor is confirmed by endocrinologic investigations along with clinical and radiographic examination. Radiographical differential diagnosis of this tumor includes central giant cell granuloma, aneurysmal bone cyst, metastatic tumor, multiple myeloma, and Paget disease. This report presents a rare case of multiple brown tumors occurring at the maxilla and mandible, which was initially misdiagnosed as central giant cell granuloma. Plain radiographs demonstrated multiple well-defined multilocular radiolucency. CT images showed soft tissue mass with low attenuated lesions, perforation of the lingual cortical plate, and a heterogeneous mass at the right thyroid lobe. These findings were consistent with parathyroid adenoma. The patient had hypercalcemia, hypophosphatemia, and elevated alkaline phosphatase level. Surgical excision of the tumor was performed. No recurrence was observed during a 28-month follow-up.

소아물리치료사와 소아작업치료사의 보조공학 활용 수준 및 자신감

김경아,정동훈,Kim, Kyoung-A,Jeong, Dong-Hoon 대한물리치료학회 2013 대한물리치료학회지 Vol.25 No.1

Purpose: This study sought to identify the utilization and confidence in assistive technology (AT) for pediatric physical therapists (PPTs) and pediatric occupational therapists (POTs) for the purpose of improving the utilization of AT in clinics. Methods: The subjects of this study were 167 therapists (98 PPTs and 69 POTs) who work at general hospitals, welfare centers, facilities for the disabled, and special education schools in Seoul and Gyeonggi province. The frequency analysis and chi-squared test were used. Results: This study found that both PPTs and POTs recognize that AT benefits infants with disabilities; however, they show low confidence in using AT. Applications of AT are concentrated on wheelchairs for mobility and assistance with seating position, with orthotics/prosthetics for both purposes. POTs were found to use a wider variety of AT devices. While both PPTs and POTs frequently select/recommend devices, both groups are less involved with delivery methods, manufacture of devices, and education on AT use. Conclusion: These findings show the actual conditions of utilization and confidence in AT of PPTs and POTs deeply involved with AT, and emphasize that AT training is essential for pediatric treatment by comparing domestic and foreign studies.

경기 지역 대기 오염 농도의 시간 변동성과 관련된 종관 기상 상태의 전개

임규호(Gyu-Ho Lim),김경아(Kyoung-A Kim) 한국기상학회 1996 Asia-Pacific Journal of Atmospheric Sciences Vol.32 No.1

폐암에서 혈중 Cyfra 21-1, SCC 항원 및 CEA의 진단적 유용성

김경아 ( Kyoung Ah Kim ),이미화 ( Me Hwa Lee ),고윤석 ( Youn Suck Koh ),김선희 ( Seon Hee Kim ),임채만 ( Chae Man Lim ),이상도 ( Sang Do Lee ),김우성 ( Woo Sung Kim ),김동순 ( Dong Soon Kim ),김원동 ( Won Dong Kim ),문대혁 ( Dae H 대한결핵 및 호흡기학회 1995 Tuberculosis and Respiratory Diseases Vol.42 No.6

팔, 손가락, 정맥에서 채취한 혈액의 혈당검사결과 비교 분석

김경아(Kim, Kyung-Ah),이인광(Lee, In-Kwang),신은영(Shin, Eun-Young),김양미(Kim, Yang-Mi),김경옥(Kim, Kyoung-Oak),차은종(Cha, Eun-Jong),박경순(Park, Kyung-Soon) 한국산학기술학회 2012 한국산학기술학회논문지 Vol.13 No.4

팔부위에서 혈당을 측정하는 것은 모세혈관에서 혈액을 채취하는 동안 느끼는 통증을 줄일 수 있다. 본 연 구에서는 팔부위 혈당검사의 임상적 유효성을 평가하기 위해 팔부위 혈당검사결과를 손가락 및 정맥에서의 혈당검사 결과와 각각 비교하였다. 당뇨환자 61명이 포함된 555명의 피검자를 대상으로 금식 상태에서 휴대형 혈당계로 손가락 과 팔 안쪽 부위에서 혈당검사를 수행하였으며, 1시간 이내에 피검자 514명의 정맥혈액으로 혈당검사를 수행하였다. 측정값들에 대해 선형회귀분석, 급내 상관분석(intraclass correlation), Passing-Bablok 회귀분석 기법으로 다양하게 비교 분석해 보았다. 팔부위 혈당값은 환자군에서 손가락 및 정맥 혈당값과의 상관계수(r)가 0.97(P<0.0001)로 높은 선형관 계를 나타내었으며, 정상군에서도 r값이 약간 작았지만 유사하였다. 채혈 부위에 따른 혈당값의 평균 차이는 두 집단 에서 모두 ±10mg/dL 이내이었다. 급내 상관계수는 r값에 비교하여 약간 작았지만 두 집단이 유사한 수치를 나타내었 다. Passing-Bablok 분석에서 기울기의 95% 신뢰구간과 절편은 각각 <±20%, <±20mg/dL로서 임상 허용범위 이내의 값을 나타내었다. 본 연구에서 사용한 세 가지 통계분석 결과 팔부위 혈당값이 손가락과 정맥에서 측정한 혈당값과 충분히 일치함이 입증되었다. 팔부위 혈당검사가 표준방법인 손가락 혈당검사와 높은 일치성을 나타내었으므로 금식 상태에서의 임상적용 가능성을 확인할 수 있었다. Capillary blood sampling on the forearm reduces pain caused by skin puncture. The present study compared the blood glucose test results performed at different sampling sites of the forearm, finger, and vein to evaluate clinical validity of this alternative site blood sampling technique. Subjects numbered 555 including 61 diabetic patients participated to measure the glucose concentration on the finger (GF) and the forearm (GA) with a portable glucometer under overnight fasting state. Then, the venous glucose concentration (GV) was measured in 514 subjects in less than 1 hour. The test results were analyzed by simple linear regression, intraclass correlation, and Passing-Bablok regression techniques. GA was highly correlated with GF or GV showing the correlation coefficients (r) of approximately 0.97 (P<0.0001) in the normal group. The patient group also resulted similarly high correlation with only slightly lower r value. The mean differences in glucose concentration were less than ±10mg/dL regardless of the sampling sites. Intraclass correlation coefficients were slightly smaller than r but very much similar in value in both groups. The 95% confidence intervals of the slope as well as the intercept in the Passing-Bablok regression analysis were <±20% and <±20mg/dL, respectively, which were within the clinically acceptable ranges. These three statistical techniques introduced in the present study well demonstrated the consistency of GA with GF and GV. Therefore, the forearm blood glucose test could be considered as clinically valid under fasting condition. Key Words : Blood glucose test, Alternative blood sampling, Comparative analysis

Magnetic and Structural Properties of Mg(Fe2-xAlx)O4 Thin Films

Kyoung Sun Kim,Seung Ho Han,Ho Gi Kim,Young Taek Lee,김경아,김정석,Chae Il Cheon 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.54 No.2

The magnetic and the structural properties of Mg(Fe2-xAlx)O4 thin films prepared by using the sol-gel method were investigated. The Mg(Fe2-xAlx)O4 thin films crystallized into the single spinel phase in air and the crystallization temperature increased from 500℃ (x = 0) to 800℃(x = 2) with increasing Al content x. The lattice constant and the grain size was decreased when the Al content increased in the Mg(Fe2-xAlx)O4 thin films annealed at 800℃. The Mg(Fe2-xAlx)O4 thin films with x ≤ 1.2 had Neel temperatures (TN) higher than room temperature while the thin films with x ≥ 1.6 lost ferrimagnetic ordering. The Mg(Fe2-xAlx)O4 thin films show the largest saturation magnetization (Ms) value of 87 emu/cm3 at x = 0.0 and the magnetization decreased with increasing Al content(x). The magnetic characteristics of the Mg(Fe2-xAlx)O4 thin films are discussed in terms of the cation distributions over the octahedral and the tetrahedral sites in the spinel structure. The magnetic and the structural properties of Mg(Fe2-xAlx)O4 thin films prepared by using the sol-gel method were investigated. The Mg(Fe2-xAlx)O4 thin films crystallized into the single spinel phase in air and the crystallization temperature increased from 500℃ (x = 0) to 800℃(x = 2) with increasing Al content x. The lattice constant and the grain size was decreased when the Al content increased in the Mg(Fe2-xAlx)O4 thin films annealed at 800℃. The Mg(Fe2-xAlx)O4 thin films with x ≤ 1.2 had Neel temperatures (TN) higher than room temperature while the thin films with x ≥ 1.6 lost ferrimagnetic ordering. The Mg(Fe2-xAlx)O4 thin films show the largest saturation magnetization (Ms) value of 87 emu/cm3 at x = 0.0 and the magnetization decreased with increasing Al content(x). The magnetic characteristics of the Mg(Fe2-xAlx)O4 thin films are discussed in terms of the cation distributions over the octahedral and the tetrahedral sites in the spinel structure.

비대면 코칭 기반 대학 비교과 프로그램 개발 및 효과성 : S여자대학교를 중심으로

김경아(Kim, Kyoung A) 한국교양교육학회 2022 교양교육연구 Vol.16 No.2

코로나 바이러스 감영증-19 이후 급변하는 사회 환경에 대처할 수 있는 다양한 비대면 비교과 프로그 램에 대한 요구가 이어지고 있다. 이에 본 연구는 S여자대학교 학생들을 대상으로 ‘미래를 여는 푸른힘’ 프로그램을 개발, 실시한 후 그 효과성을 탐색하고자 한다. 이를 위해 비교과 시스템을 통하여 실험집단과 통제집단 각 20명씩을 선정하였다. 또한 프로그램의 효과성을 파악하기 위하여 양적⋅질적 접근을 실시하였다. 프로그램은 리더십 워크숍, 리더십 진단, 그룹 코칭, 일대일 코칭 등으로 구성되었으며, 모두 온라인 플랫폼 줌(zoom)으로 2022년 1월 17일 ~ 2월 24일까지 총 7회차 진행되었다. 프로그램 실시 결과, 실험집단은 진로결정자기효능감과 회복탄력성에서 사전-사후검사 간에 유의한 차이를 나타냈다. 또한, FGI 분석 결과 프로그램 모델, 자기이해의 확장, 미래 비전의 고도화 등의 총 3개 범주가 도출되었다. 이상과 같이 본 프로그램은 진로결정에 대한 확신과 긍정 에너지를 함양시킬 뿐 아니라 나아가 글로벌 리더로서의 미래 설계를 고취시키는데 기여했음을 알 수 있다. Demand for various non-face-to-face, non-curricular programs that can cope with the rapidly changing social environment after Corona-19 continues. Therefore, this study aims to explore the effectiveness of S Women s University students after developing and implementing the ‘Blue Power to Open Tomorrow’ program. For this purpose, 20 university students each were selected from the experimental group and the control group through the non-examination system. In addition, quantitative and qualitative approaches were implemented to understand the effectiveness of the program. The program consisted of a leadership workshop, a leadership diagnosis group-coaching section, and one-on-one coaching activities, all of which were conducted through online platform Zoom from January 17th to February 24th, 2022. As a result of the program’s implementation, the experimental group showed a significant difference regarding their pre-test and post-test scores in the areas of career decision self-efficacy and resilience. In addition, as a result of FGI analysis, a total of three categories were derived: the program model, the expansion of self-understanding, and the advancement of future vision. As mentioned above, we can see that this program not only fostered confidence in students when it came to their ability to make career decisions, but that it also inspired them in their future designs as global leaders and instilled in them a marked level of positive energy.