한국의 교도소도서관 현황분석과 개선방안

권세희,윤혜영,Kwon, Se-Hee,Yoon, Hye-Young 한국과학기술정보연구원 과학기술정보센터 2009 Journal of Information Science Theory and Practice Vol.40 No.3

이 연구의 목적은 인권의 사각지대에 있는 교정시설 내에 구금된 수용자들을 대상으로 정보를 제공하는 교도소도서관의 현황을 분석하여 그 문제점을 도출하고 개선방안을 제시하는 것이다. 교도소도서관 현황을 파악하기 위하여 시설 및 설비와 인적 자원, 보유도서현황과 대출현황 그리고 예산현황 등에 이르기까지 종합적으로 통계자료를 토대로 정리 분석하였다. 문화체육관광부의 국가도서관 통계시스템사이트(2008년 기준: 2007년 $1{\sim}12$월 조사)와 2008년 발간한 '도서관발전종합계획(2009-2013)', 교도소에 정보공개청구를 통하여 얻은 '관용도서 비치 및 활용현황' 문서 34건을 이용하여 교도소도서관의 시설, 인적 자원, 장서, 서비스, 예산 등의 실태를 조사하였다. 이러한 현황 조사내용을 토대로 하여 한국교도소도서관의 문제점을 추출해 보고 이에 대한 발전방향을 모색하였다. This study aims to investigate current situation and improvement method of correctional facility libraries in Korea. Thus this study made the following suggestions to improve the operation of correctional facility library and to facilitate its growth so that the inmates' basic right to know and access information could be guaranteed: First, there should institutional and legal grounds for the establishment and operation of correctional facility library such as standards, guidelines, and enactments; second, the government should provide enough budgets for human and material resources so that a prison library can equip itself with materials, facilities, and staff to run smoothly; third, the inmates' free access to the library service should be guaranteed in an open space; fourth, the library should introduce an automation system for lending, returning, and handling materials; fifth, a collaboration system with external resources should be set up to make effective use of lacking resources; sixth, programs should be researched and developed to analyze the size and composition of the inmates, the needs of the inmates, and available service; and finally, there should be staff with the qualification of a librarian to be responsible for the operation and management of a correctional facility library and to offer specialized library service to the inmates.

Quality of Life and Awareness of Cardiac Rehabilitation Program in People With Cardiovascular Diseases

권세희,손민균,정진옥,김수재,전현규,이혜원,안승찬,박수호,지성주 대한재활의학회 2017 Annals of Rehabilitation Medicine Vol.41 No.2

Objective To evaluate the level of health-related quality of life (HRQoL), life satisfaction, and their present awareness of cardiac rehabilitation (CR) program in people with cardiovascular diseases.Methods A questionnaire survey was completed by 53 patients (mean age, 65.7±11.6 years; 33 men and 20 women) with unstable angina, myocardial infarction, or heart failure. The questionnaire included the Medical Outcome Study 36-item Short-Form Health Survey (MOS SF-36), life domain satisfaction measure (LDSM), and the awareness and degree of using CR program.Results The average scores of physical component summary (PCS) and mental component summary (MCS) were 47.7±18.5 and 56.5±19.5, respectively. There were significant differences in physical role (F=4.2, p=0.02), vitality (F=10.7, p<0.001), mental health (F=15.9, p<0.001), PCS (F=3.6, p=0.034), and MCS (F=11.9, p<0.001) between disease types. The average LDSM score was 4.7±1.5. Age and disease duration were negatively correlated with multiple HRQoL areas (p<0.05). Monthly income, ejection fraction, and LDSM were positively correlated with several MOS SF-36 factors (p<0.05). However, the number of modifiable risk factors had no significant correlation with medication. Thirty-seven subjects (69.8%) answered that they had not previously heard about CR program. Seventeen patients (32.1%) reported that they were actively participating in CR program. Most people said that a reasonable cost of CR was less than 100,000 Korean won per month.Conclusion CR should focus on improving the physical components of quality of life. In addition, physicians should actively promote CR to cardiovascular disease patients to expand the reach of CR program.

Cathepsin B & D and the Survival of Early Embryos in Red Spotted Grouper, Ephinephelus akaara

권세희,김현규,백해자,이영돈,권준영 한국발생생물학회 2017 발생과 생식 Vol.21 No.4

Survival of embryos largely depends on yolk processing during early development. Proteolytic enzymes, ca-thepsin B & D (ctsb & ctsd) are known to have some important roles in yolk processing of various fish species. Mature female red spotted groupers were injected with human chorionic gonadotropin (HCG) to induce ovulation. The fertilized eggs and embryos were sampled at 0, 4 and 24 HPF (hours post fertilization). Survivals of each groups of embryos were checked at 24 and 48 HPH (hours post hatching). Transcripts of ctsb & ctsd showed the highest level at 0 HPF and relatively high at 4 HPF, but greatly decreased at 24 HPF. In bad egg quality group (BE, embryos survived until 24 HPH), transcript level of ctsb at 4 HPF were significantly lower than the transcript level at the same stage in good egg quality group (GE, embryos survived un-til 48 HPH) while no significant change of ctsb transcript level was observed at 0 or 24 HPF between BE and GE. Transcript level of ctsd was decreased at 24 HPF, but the difference was not as strong as the case of ctsb transcript. These results suggest that maternal ctsb transcript rather than ctsd transcript is likely to be involved in egg quality resulting in the difference of sur-vival rate of embryos at early developmental period in this species.

마그네트론 2원 동시 방전법을 이용하여 polymer 기판위에 증착한 비정질 ITZO박막의 Zn 함량 효과

권세희,강용민,이건환,송풍근 한국표면공학회 2009 한국표면공학회 학술발표회 초록집 Vol.2009 No.-

Polymer 기판위에 증착된 ITZO 박막의 TiO₂ 버퍼층 두께에 따른 전기적, 기계적 특성

권세희,강용민,송풍근 한국표면공학회 2009 한국표면공학회 학술발표회 초록집 Vol.2009 No.10

ITZO 박막과 TIO2 버퍼층은 각각 두 개의 캐소드를 사용한 마그네트론 2원동시 방전법과 산소 함량 2%를 사용한 반응성 sputtering 방법으로 각각 증착이 되었다. 모든 박막들은 상온에서 폴리머 기판인 PET에 증착되었다. TiO₂ 버퍼층을 도입함으로써 ITZO/TiO₂ 박막은 비정질 구조를 보여 주었고, 그것들의 비저항은 버퍼층의 두께가 증가할수록 감소함을 관찰하였다. 특히 기계적 특징은 TiO₂ 버퍼층을 5㎚ 증착하였을 경우에 bending test와 광학 현미경의 crack정도를 관찰함으로써 향상되었음을 확인할 수 있었다. 투과율에 있어서 단일 ITZO 박막과 버퍼층을 5㎚ 도입한 박막은 가시광선에서 약 75%의 투과율을 가짐을 알 수 있었다.

Change of Swallowing in Patients With Head and Neck Cancer After Concurrent Chemoradiotherapy

권세희,구본석,지성주 대한재활의학회 2016 Annals of Rehabilitation Medicine Vol.40 No.6

Objective To evaluate the functional characteristics of swallowing and to analyze the parameters of dysphagia in head and neck cancer patients after concurrent chemoradiotherapy (CCRT). Methods The medical records of 32 patients with head and neck cancer who were referred for a videofluoroscopic swallowing study from January 2012 to May 2015 were retrospectively reviewed. The patients were allocated by duration after starting CCRT into early phase (<1 month after radiation therapy) and late phase (>1 month after radiation therapy) groups. We measured the modified penetration aspiration scale (MPAS) and American Speech-Language-Hearing Association National Outcome Measurement System swallowing scale (ASHA-NOMS). The oral transit time (OTT), pharyngeal delay time (PDT), and pharyngeal transit time (PTT) were recorded to assess the swallowing physiology. Results Among 32 cases, 18 cases (56%) were of the early phase. In both groups, the most common tumor site was the hypopharynx (43.75%) with a histologic type of squamous cell carcinoma (75%). PTT was significantly longer in the late phase (p=0.03). With all types of boluses, except for soup, both phases showed a statistically significant difference in MPAS results. The mean ASHA-NOMS level for the early phase was 5.83±0.78 and that for the late phase was 3.79±1.80, with statistical significance (p=0.01). The PTT and ASHA-NOMS level showed a statistically significant correlation (correlation coefficient=–0.52, p=0.02). However, it showed no relationship with the MPAS results.Conclusion The results of our study suggest that in the late phase that after CCRT, the OTT, PDT, and PTT were longer than in the early phase and the PTT prolongation was statistically significant. Therefore, swallowing therapy targeting the pharyngeal phase is recommended after CCRT.

Flexible 기판위에 증착된 ITZO 박막의 내부응력에 대한 TiO₂ 버퍼층 두께의 영향

권세희,송풍근 한국표면공학회 2010 한국표면공학회 학술발표회 초록집 Vol.2010 No.11

ITO / CeO₂ / PI 박막의 기계적, 전기적 및 광학적 특성

강용민,권세희,송풍근 한국표면공학회 2009 한국표면공학회 학술발표회 초록집 Vol.2009 No.10

마그네트론 스퍼터링법을 이용하여 투명 Polyimide 기판과 ITO 박막 사이에 다양한 두께의 CeO₂ 버퍼층을 증착 후 기계적, 전기적, 광학적 특성을 조사하였다. CeO₂ 버퍼층의 두께가 증가함에 따라서 degassing 현상의 감소로 인해 전기적 특성의 개선 및 부착력의 증가를 확인할 수 있었으며, 5㎚ 두께의 CeO₂ 버퍼층이 삽입된 ITO/CeO₂ 박막에서 가장 우수한 기계적 특성을 확인할 수 있었다.

폴리이미드 기판위에 증착한 고온내구성 비정질 ITO:Ce 박막의 특성

강용민,권세희,송풍근 한국표면공학회 2009 한국표면공학회 학술발표회 초록집 Vol.2009 No.-

Sumoylation of histone deacetylase 1 regulates MyoD signaling during myogenesis

정호석,권세희,김경훈,이윤경,신세라,권덕화,이영운,국태원,최낙원,김정철,김영국,엄광현,국현 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-

Sumoylation, the conjugation of a small ubiquitin-like modifier (SUMO) protein to a target, has diverse cellular effects. However, the functional roles of the SUMO modification during myogenesis have not been fully elucidated. Here, we report that basal sumoylation of histone deacetylase 1 (HDAC1) enhances the deacetylation of MyoD in undifferentiated myoblasts, whereas further sumoylation of HDAC1 contributes to switching its binding partners from MyoD to Rb to induce myocyte differentiation. Differentiation in C2C12 skeletal myoblasts induced new immunoblot bands above HDAC1 that were gradually enhanced during differentiation. Using SUMO inhibitors and sumoylation assays, we showed that the upper band was caused by sumoylation of HDAC1 during differentiation. Basal deacetylase activity was not altered in the SUMO modification-resistant mutant HDAC1 K444/476R (HDAC1 2R). Either differentiation or transfection of SUMO1 increased HDAC1 activity that was attenuated in HDAC1 2R. Furthermore, HDAC1 2R failed to deacetylate MyoD. Binding of HDAC1 to MyoD was attenuated by K444/476R. Binding of HDAC1 to MyoD was gradually reduced after 2 days of differentiation. Transfection of SUMO1 induced dissociation of HDAC1 from MyoD but potentiated its binding to Rb. SUMO1 transfection further attenuated HDAC1-induced inhibition of muscle creatine kinase luciferase activity that was reversed in HDAC1 2R. HDAC1 2R failed to inhibit myogenesis and muscle gene expression. In conclusion, HDAC1 sumoylation plays a dual role in MyoD signaling: enhancement of HDAC1 deacetylation of MyoD in the basally sumoylated state of undifferentiated myoblasts and dissociation of HDAC1 from MyoD during myogenesis.