Debrisoquin의 家兎血壓에 미치는 影響

姜浩淵 朝鮮大學校 1981 藥學硏究誌 Vol.4 No.1

Debrisoquin은 交感神經遮斷, 特히 交感神經의 節後織維의 neuroeffector site에 있는 神經末端의 catecholamine 貯藏所로부터 norepinephrine의 遊離를 抑制하여 交感神經의 tone을 弱化시키는 藥理作用이 있다고 하여 高血壓治療에 使用되어왔다. 이 debrisoquin은 tetrahydroquin 誘導體로서 guanethidine과는 그 구조식이 相異하나 交感神經遮斷作用은 guanethidine과 類似한 것으로도 알려저 있다. 그러나 guanethidine은 neuroeffector site에서 norepinephrine의 遊離抑制作用外에 tyramine 및 reserpine類似作用이 있는 것으로 알려저 있는데 反하여 debrisoquin은 MAO 억제 作用이 있다고 報告된 바가 있다. debrisoquin의 藥理作用이 guanethidine과는 一致하지 않은 여러 가지 複雜한 作用들이 있을것으로 思料되어 이 debrisoquin의 藥理作用을 具體的으로 把握하기 위하여 家兎을 利用하여 血壓에 對해 影響을 觀察하고저 하였다. Influences of debrisoquin, which was reported as the sympathetic neuronal blocking agent, on the blood pressure were investigated in the whole and the spinal rabbits, Debrisoquin, when administered into the vein or lateral ventricle, produced fall of blood pressure. Intravenous debrisopuin elicited elevation of blood pressure in spinal rabbits. The hypotensive action by debrisoquin in whole rabbits was inhibited by pretreatment of chlorisondamine or phentolamine but not by atropine or propranolol. The hypotensive actions produced by debrisoquin in whole rabbits pretreated with chlorisondamine and the hypertensive actions by debrisopuin in spinal rabbits were weakened by atropine and phentolamine, respectively. In whole rabbits, debrisoquin potentiated the pressor responses to norepinephrine, tyramine or DMPP but did not affect on the pressor responses to angiotensin and markedly inhibited the pressor responses by carotid artery occlusion. Above results suggest that debrisoquin produces the fall of blood pressure by central blockade of sympathetic nerves.

특수학교에 근무하는 특수교사의 개인적 변인에 따른 공감피로와 공감만족 수준 분석

강호연,박성서,한아름,남광현,서효정 공주대학교 특수교육연구소 2020 특수교육논집 Vol.24 No.2

이 연구의 목적은 특수학교에 근무하는 특수교사의 배경 변인(성별, 연령, 학력, 교육경력, 과정, 담임여부 및 담임교사일 경우 학생 수)에 따른 공감피로와 공감만족의 수준을 알아보고자 하였다. 이를 위해 대전광역시, 인천광역시, 강원도, 충청도에 소재하고 있는 특수학교에 근무하고 있는 특수교사를 대상으로 설문지를 배부하여 146부를 최종 분석에 활용하였다. 연구 결과, 첫째, 공감피로 영역에서 이차 외상성 스트레스는 성별 변인에서 통계적으로 유의미한 차이를 보였다. 구체적으로 남자 특수교사보다 여자 특수교사가 장애가 있는 학생에게 이차 외상성 스트레스를 더 잘 경험한다는 것으로 나타났다. 둘째, 소진과 공감만족 부분에서는 배경 변인에 따라 통계적으로 유의미한 부분은 없었다. 이러한 연구 결과를 종합해보면, 특수학교에 근무하는 특수교사의 이차 외상성 스트레스는 성별 변인에 있어서만 통계적으로 유의미한 차이를 보이고, 다른 배경 변인에 의한 차이나 소진에 있어서는 차이를 보이지 않았다. 실제로, 산출된 점수는 평균 25.59(SD=5.60)이었고, 특수학교에 근무하는 모든 특수교사는 이와 비슷한 점수인 평균 수준으로 공감피로를 느끼고 있다. 따라서 특수교사의 심리적 어려움을 덜기 위해서는 법적, 제도적 차원의 지원이 필요하고, 공감만족을 높일 수 있는 다른 방안들이 강구되어야 할 것이다. The purpose of this study was to compare compassion fatigue and compassion satisfaction by individual variables(gender, age, level of education, teaching experiences, grade levels, and the number of students in each classroom) of special education teachers in special schools. For this, surveys of compassion fatigue and compassion satisfaction were collected from 146 teachers in special-education school in Dajeon, Incheon, Kangwondo and Chungcheongnamdo province, and the results were analyzed through t-test and F test. First, secondary traumatic stress of compassion fatigue was statistically different by gender. Specifically, female special educators had more empathy to students with disabilities than male teachers did. Second, burnout and compassion satisfaction were not statistically different by participantsʼ personal variables. Seeing from the above results, all special teachers in the special schools had psychologically compassion fatigue. Thus, there are urgent needs for legal and institutional supports in order to minimize mental difficulties of special teachers. In addition, other active ways to raise special educatorsʼ compassion satisfaction should be provided.

감정인식을 위한 생체신호 실시간 수집 웨어러블 기기 개발

강호연,김형석 제어로봇시스템학회 2023 제어로봇시스템학회 국내학술대회 논문집 Vol.2023 No.6

Long-Term Outcome of Reattached Tooth Fragment in Permanent Anterior Teeth of Children and Adolescents

강호연,채용권,이고은,이효설,최성철,남옥형,Kang, Hoyeon,Chae, Yongkwon,Lee, Koeun,Lee, Hyo-seol,Choi, Sungchul,Nam, Okhyung Korean Academy of Pediatric Dentistry 2021 大韓小兒齒科學會誌 Vol.48 No.1

This study aimed to evaluate the long-term outcomes of teeth treated with reattachment technique in children and adolescents. Twenty seven permanent anterior teeth from 21 patients treated with fragment reattachment were evaluated. Clinical photos and medical records were used to assess treatment outcomes. Effect of pulp treatment and the ratio of fragment on success rate were statistically analyzed. Detachment of fragment was observed in 17 teeth, and their duration of retention was 21.41 ± 23.39 months. Repeated trauma was found to be the most frequent causes of failure. Pulp treatment before reattachment did not affect the success rate (p > 0.05). The mean ratio of fragment was 0.482 ± 0.147, and the success rate was affected by the ratio of fragment (p = 0.018). The median retention time of the teeth was 72 months if the ratio was under 0.5, and 8 months for that of the others. A significant correlation was found between the ratio of fragment and retention time (p = 0.003). Reattachment can be a predictable treatment option for crown fracture in anterior teeth in children and adolescents when a fracture involves less than 50% of the clinical crown. 이 연구의 목적은 소아 및 청소년의 영구치 치관 파절시 파절편 재부착술의 추적 관찰 결과를 평가하고자 함에 있다. 21명의 27개의 영구치 파절편 재부착술을 시행한 환자를 대상으로 임상 사진, 방사선 사진 및 의무기록을 활용하여 평가하였다. 파절편 탈락은 총 17개 치아에서 관찰되었으며 반복적인 외상이 가장 빈번한 실패 원인이었다. 파절편 재부착술과 치수치료 시행 유무는 통계적으로 유의미하지 않았다(p > 0.05). 평균 파절편 비율은 0.482 ± 0.147이며 성공률은 파절편 비율과 유의미한 상관관계를 나타냈다(p = 0.018). 평균 파절편 유지 기간은 72개월이며 파절편 유지 기간과 파절편의 비율은 통계적으로 유의미한 상관관계를 나타냈다(p = 0.003). 소아 및 청소년의 영구치 치관 파절시 파절편 비율이 50% 미만인 환자에서 파절편 재부착술은 예측 가능한 치료 방법이 될 수 있다고 판단된다.

Genotoxicity screening of chemical additives in plastics using Human XPA knockout cell

강호연,최진희 환경독성보건학회 2019 한국독성학회 심포지움 및 학술발표회 Vol.2019 No.10

목통 Ethanol Extract 의 혈압강하작용에 관한 연구

강호연 한국약제학회 1979 Journal of Pharmaceutical Investigation Vol.9 No.2

Effects of Akebiae Lignum, whose scientific name is Akebia quinata Decaisne, on the blood pressure were investigated with EtOH extract in whole and spinal rabbits. Akebia Lignum EtOH extract (AEE), when given intravenously, produced a fall in blood pressure not only in whole rabbit but also in spinal rabbit and AEE administered into a lateral cerebral ventricle of whole rabbit did not elicit a fall in blood pressure. The depressor responses of the whole rabbit to intravenous AEE were weakened by treatment of the animals with atropine and chlorisondamine but not by vagotominijation, phentolamine avil, and then the depressor action causing by AEE in the whole rabbit was not affected by pretreatment of physostigmine which is cholinesterase inhibitor and of hemicholinium which blocks acetylcholine synthesis by interfering with choline uptake in nerves. These observations suggest that the hypotensive action of AEE of which component is not affected by cholinesterase is due to direct action at parasympathetic receptor.

현대 교육과정기 말하기 교육 변천사

강호연(Ho-Yeon Kang),오현아(Hyeon-Ah Oh) 한국중원언어학회 2012 언어학연구 Vol.0 No.25

In this study, I observed the development of speech education in the Korean Education system which was analyzed by reflecting rate in the curriculum. From 1st curriculum to 7th, the speech education has been changed a lot. The 1st and 2nd curriculum were almost similar as speaker-based, and the 3rd and 4th attempted to divide small things but they didn"t have reality. At the beginning of 5th, it is changed to the learner-based, so this was applied to the textbook. There is a difference between curriculum and applying it to textbook in the times. In 1st curriculum, it had a value for beginning of speech education. In textbook, however, there was no distinction The 2nd had been showed better than before by setting speech chapter and offering various learning activities in textbook. The 3rd textbook had also increased to reflect curriculum so that it"s developed. But the 4th had a clear difference from the 3rd by not setting speech chapter separately. These changes show us that textbook compilers tried to get out of previous chapter setting system. 5th started to divide sections and let learners know what they study in each chapter. 6th was similar to 5th, and 7th was composed of language and living language, so learners can experience more various forms of speech education. From the revised 7th, however, the textbook was changed national into authorized and also language part were reunited with living language into one. It is trying to integrate the sections in each chapter.

내수기업 수출활성화를 위한 무역전문인력 양성 방안에 대한 연구

강호연(Ho Yeon KANG),정윤세(Yoon Say JEONG) 한국무역상무학회 2018 貿易商務硏究 Vol.78 No.-

In all countries of theworld, the development of trade is an important factor for the survival of the national economy. Increased export will lead to national economic growth. Export is directly linked to employment, and the industrial structurewill be developed in the direction to produce products of comparative advantages. Therefore, every country around the world is trying to promote export regardless of the size of its economy. Accordingly, this paper focused on the promotion of export of domestic companies. It proposed to cultivate trade experts to promote export of domestic companies. The following five methods were proposed to materialize the proposal. First, it is important to foster trade experts to expand and foster the one-person creative companies. In particular, it is important to develop a professional education curriculum. It is necessary to design and conduct a systematic curriculum throughout the process including follow-up after education such as teaching detailed procedures for establishing a trade business, identification of relevant regulations and related organizations, understanding of special features of each exporting country, and details of exporting procedures through specialist training for the individual industries, helping themto keep their network steady so that they can easily get help from consultants. Second, it is necessary to educate tradersworking in the field tomake them trade experts and utilize themin on-the-job training and consulting. To do this, it is necessary to introduce systematic consultant selection process, and to introduce a systemto educate andmanage them. It is because,wemust select themost appropriate candidates, educate themto be lecturers and consultants, and dispatch themto the field, in order tomake the best achievement in export. Nurturing trading professionals utilizing the current tradingworkers to activate export of domestic companies can be more efficient through cooperation of trading education agencies and related agencies in various industries. Third, it is also proposed to cultivate female trade experts by educating female tradeworkerswhose career has been disrupted. It is to provide career disrupted women with opportunities to work after training them as trade professionals and to give manpower pool to domestic companies that are preparing for export. Fourth, it is also proposed to educate foreign students living in Korea to be trading experts and to utilize them as trading infra. They can be trading professionalswhowill contribute to the promotion of export. In the short term, theywill be providedwith opportunities for employment and start-upin the field of trade, and in themid- to long-term, theymay develop a business network between Korea and their own countries. To this end, we need to improve the visa system, expand free trade education opportunities, and support themso that they can establish small but strong enterprises. Fifth, it is proposed to proactively expand trade education to specialized high school students. Considering that most of domestic companies pursuing activation of export are small but strong companies or small andmediumsized companies, they may prefer high school graduates rather than university graduates because of financial limitations. Besides, the specialized high school studentsmay occupy better position in the jobmarket if they are equippedwith expertise in trading. This study can bemeaningful, in that it is the first research that focuses on cultivating trading experts to contribute to the export activation of domestic companies. However, it also has a limitation that it has failed to reflect themore specific field voices. It is hoped that detailed plans will be derived from the opinions of the employees of domestic companiesmaking efforts to become an export company in the related researches in the future.

청소년기 자폐성장애 학생을 대상으로 한 개인중심계획 수립 및 실행 사례연구

강호연 ( Kang¸ Hoyeon ),서효정 ( Seo¸ Hyojeong ) 대구대학교 한국특수교육문제연구소 2021 특수교육저널 : 이론과 실천 Vol.22 No.3

[목적] 이 연구의 목적은 특수교사들이 아동용 지원정도척도를 활용하여 개인중심계획을 수립하고 실행하는 과정 속에서 겪은 경험 분석이다. [방법] 2020년 9월부터 12월까지 두 명의 청소년기 자폐성장애 학생을 대상으로 개인중심계획 철학을 반영하여 개인지원계획 회의 및 면담을 실시하고, 수업일지를 작성하며 사례연구를 실시하였다. [결과] 개인중심계획을 수립하고 적용하는 과정 속에서 학생이 직접 회의에 참여하여 자신의 장점, 미래계획, 흥미 등을 살펴볼 수 있었고, 특수교사와 학부모가 협력하여 개인지원목표를 수립·달성하고자 노력하였다. 이 과정에서 특수교사가 교육계획을 수립하는데 집중해야 할 우선순위를 아동용 지원정도척도를 활용하여 파악할 수 있었고, 교육지원계획의 목표를 달성하기 위해 학부모와 학생은 협력하였다. 다음으로, 개인중심계획 철학을 적용한 개인지원계획을 수립하고 실행하는 과정에서 도출된 의미는 개인중심계획에서의 개인은 처음부터 끝까지 당사자 중심이며, 개인중심계획 철학을 반영하기 위해 협력하는 공동체로 이루어지고, 마지막으로 개인중심계획이 학교 현장에서 적용하기에는 멀고도 험한 길로 범주화 되었다. [결론] 개인중심계획을 학교 현장에서 실현할 때 개인지원계획과 개별화교육계획이 함께 어우러질 필요가 있으며, 이를 위해 학생 지도 방법의 유연화 및 교육과정 재구성은 필수적이다. [Purpose] The purpose of this study was to examine the experiences of special education teachers at a special school while they established and implemented personal-centered plans that utilize the Supports Intensity Scale for children. [Method] Data were collected through meetings, interviews, and class logs from September to December 2020 and a case study was conducted. [Results] The students participated in their person-centered plan meetings and tried to reach their own goals with supports from special teachers and parents based on their strengths and aspirations. During this process, the priority for the special teachers to focus on in class was determined and both parents and students cooperated systematically with each other. The implications of implementing person-centered plans were as follows: (a) the person-centered planning placed the student at the center of the overall process from the beginning to the end, (b) stakeholders worked together to reflect the philosophy of person-centered planning in their own classes, and (c) there is still a long way to go in order to successfully implement person-centered plans. [Conclusion] When person-centered plans are applied at school sites, They should be harmonized with each student’s individualized education plan. In addition, flexible instructional designs and instruction reconstruction need to be considered.

남성 캐릭터가 스스로 김치를 꺼내먹나요?

호연(강호연) 한국여성민우회 2020 함께가는 여성 Vol.230 No.-