주사(Rosacea)의 한약 치료에 대한 체계적 문헌고찰 및 메타분석

강은정,감은영,김서희,윤석영,전석희,최정화,김종한,박수연,정민영,Kang, Eun-Jeong,Kam, Eun-Young,Kim, Seo-Hee,Yoon, Seok-Yeong,Jeon, Seok-Hee,Choi, Jung-Wha,Kim, Jong-Han,Park, Soo-Yeon,Jung, Min-Yeong 대한한방안이비인후피부과학회 2021 한방안이비인후피부과학회지 Vol.34 No.3

Objectives : This review was conducted to validate the effectiveness and safety of herbal medicine combined with conventional therapy for rosacea. Methods : Randomized controlled trials(RCTs) reporting the effects of herbal medicine treatment on rosacea were searched through eight electronic databases from 2016 to March 17, 2020. This study collection and data extraction were performed by two independent reviews. The Cochrane risk-of-bias tool was used for the evaluation of the risk of bias in all included RCTs. Mean differences(MD) and Risk ratio(RR) of 95% Confidence intervals(Cls) were calculated and data synthesis was conducted using Review Manager(RevMan, ver.5.4) Results : Eighteen RCTs were included and all trials compared the combined therapy of herbal medicine with conventional western therapy to conventional therapy alone. The effective rate of the combination of herbal medicine with western medicine(RR 1.20, 95% CI : 1.13-1.28, p<0.00001, I²=0%), the effective rate of the combination of herbal medicine with laser-based therapy(RR 1.12, 95% CI : 1.04-1.21, p=0.004, I²=18%) and the effective rate of the combination treatment group using herbal medicine, western medicine and external drugs were all statistically higher that of the control group(RR 1.19, 95% CI : 1.11-1.28, p<0.00001, I²=0%). The score of non transient erythema(MD -0.36, 95% CI : -1.01 0.29, p=0.27, I²=93%), flushing(MD -0.69, 95% CI : -0.97, 0.41, p<0.00001, I²=32%), papules or pustules(MD 0.10, 95% CI : -0.15, 0.35 p=0.44, I²=0%) were also seen in the herbal medicine and western medicine combination group. The overall risk of bias of the included studies was some concerns. No serious adverse effects were observed. Conclusions : This review found the safety and effectiveness of the combined therapy of herbal medicine with conventional western therapy for rosacea.

청소년의 건강상태 평가에 있어서 청소년과 부모의 차이

강은정(Kang Eun-Jeong) 한국청소년정책연구원 2008 한국청소년연구 Vol.19 No.4

본 연구의 목적은 청소년의 주관적 건강상태에 대한 청소년과 부모의 평가의 일치 정도와 그 차이에 관련된 인구사회학적 요인들을 파악하는 것이다. 분석에 사용된 자료는 청소년의 주관적 건강상태에 대하여 청소년과 부모에게 동일한 문항을 조사한 2005년 국민건강영양조사의 아동 및 청소년 건강면접조사와 청소년 보건의식행태조사 자료였다. 분석 결과 우리나라 청소년의 건강에 대한 청소년과 부모의 평가의 일치도는 비교적 낮은 편인 것으로 나타났다. 청소년의 건강상태에 대한 판단의 청소년과 부모의 불일치는 청소년이 우울감, 스트레스, 비만 인식이 있을 때 커지는 것으로 나타났다. 따라서 부모가 대리로 청소년의 건강상태를 평가할 때는 청소년의 정신적인 요소들을 고려하여야 할 필요가 있다. The purpose of this study was to assess the degree of agreement between an adolescent and his/her parent in terms of the adolescent's health status and to uncover demographic and socioeconomic factors that might be related to theirdisagreement. The data used in the analyses included the Health Interview Survey for children and adolescents and the Health Belief and Behavior Survey for adolescents, taken form the2005 Korean National Health and Nutrition Examination Survey. These two surveys contained the same question on the subjective health status of adolescents. The results showed that the degree of agreement between an adolescent and his/her parent on his/her health status was relatively low. Factors such as depression, stress, and the perception of obesity were related to the degree of disagreement between the two response sources. In conclusion, the mental health status of adolescents and their parents needs to be considered, when a parent's response is used as a proxy for an adolescent's subjective health status.

교육수준과 주관적 불건강-매개 요인의 탐색

강은정 ( Eun Jeong Kang ) 한국보건경제정책학회 2008 보건경제와 정책연구 Vol.14 No.1

Although the relationship between socioeconomic position and health inequality has been established, studies on how socioeconomic position affects health inequality are not sufficient in Korea. The purpose of the study was to find out those factors that mediate the relationship between education attainment, an indicator of socioeconomic position, and subjective health status. In detail, using the Korea National Health and Nutrition and Examination Survey in 1998, 2001, and 2005, the study (1) checked if educational attainment affected subjective health status, (2) identified the mediators of educational attainment and subjective health status, and (3) analyzed how much each mediator contributed to the difference in subjective health status by educational attainment for each year. The study results showed that lower educational attainment was related to higher rate of subjective unhealthiness. However, the evidence was not sufficient that health inequality by educational attainment has increased since 1998. The mediators between educational attainment and subjective unhealthiness were slightly different across the study years. The extent that each mediator contributed to the difference in subjective unhealthiness by educational attainment was also different across the study years. In general, disease factors for men and women and behavior factors for women were found to mediate educational attainment and subjective unhealthiness. Interventions associated with these mediators could reduce the difference in subjective health status by educational attainment.

인공지능 기반의 융복합 예술창작물 사례 분석 및 고찰

강은정(Kang, Eun Jeong),장윤영(Jang, Yun Young),이보아(Rhee, Boa) 한국전시산업융합연구원 2018 한국과학예술융합학회 Vol.35 No.-

4차 산업혁명의 도래와 함께, 인공지능 기술은 창의성이 요구되는 예술창작으로 그 적용 영역이 확장되고 있다. 본 연구는 문헌연구를 통해 다학제적 융합연구의 관점에서 ‘예술창작의 수단’으로서의 인간의 창의성과 인공지능이 융합된 예술창작물의 사례를 학습 모델과 관람객의 참여형태를 기반으로 분석하고, 융합적 관점에서 인공지능 기반의 예술창작물의 의미를 조명하는데 그 목적을 두고 있다. 본 연구에서 다룬 인공지능 기반의 상호작용형 예술창작물은 관람객을 참여자나 공동 창작자로 전환시키면서 예술창작에 대한 관람객의 역할에 새로운 의미를 부여했으며, 궁극적으로 인간과 인공지능간의 관계성에 대한 성찰을 강화시켰다. 한편 인공지능 기반의 비상호작용형 예술창작물의 경우, 기계학습을 통해 이미지의 특징을 독창적인 방식으로 해석하고 새로운 이미지를 생성했다. 특히 일부 창작물의 경우에는 인공지능의 사유 가능성과 인공지능에 의해 생성된 예술창작물의 가치에 대한 관심을 증대시켰다. 결론적으로, 인간과 인공지능의 융합을 통해 탄생한 예술창작물은 인간과는 상이한 방식으로 데이터를 해석 및 표현할 수 있기 때문에, 창작자에게는 새로운 창작 소재나 창작 방식의 혁신을 통해 예술과 테크놀로지의 융합에 대한 새로운 지평을 열어 주었고, 관람객에게는 시각적 이미지에 대한 새로운 경험의 기회를 제공해 주었다. With the advent of the 4th industrial revolution, artificial intelligence technology extends its applying to art creation area, which requires creativity. From the perspective of interdisciplinary research, this study aims to analyze new forms of art creation from the convergence of human creativity and artificial intelligence (hereafter A.I.), based on A.I. learning models and participation forms of viewer through the case studies and literature review. In addition, it contributes to shed light on the meanings of art creations using A.I. in terms of convergence research. The interactive artworks based on A.I. discussed in this study have given new meaning to the role of spectators in art creation by turning viewers into participant as well as co-creator. Also, it ultimately let people reflect upon the relationship between human and A.I. On the other hand, in the case of non-interactive creative artworks based on A.I., machine learning was used to interpret image’s features to its own unique way and create into new images. Especially in the case of some creations, the creations augmented the interest in the value of artistic creations made by A.I.. In conclusion, because artistic creations created through the convergence of human beings and A.I. can interpret and express data in a way that differ from human beings, it opens up new horizons of the convergence of art and technology for creators to innovate through new creative materials and creative methods and gives visitors a new opportunity to experience visual images.

Rasch 모형을 적용한 여성신체활동척도 비교

강은정(Eun Jeong Kang),박재현(Jae Hyeon Park) 한국체육측정평가학회 2014 한국체육측정평가학회지 Vol.16 No.2

이 연구는 신뢰도분석과 요인분석만으로 개발되는 척도를 보완하기 위해 Rasch 모델을 이용하여 연령대별 한국여성에게 타당한 신체활동척도를 개발하는 데 목적이 있다. 개발하는 신체활동척도의 신뢰도와 타당도를 높이기 위해 동 일하지 않은 연구대상으로 예비검사와 본검사를 실시하였다. 예비검사는 서울, 경인 지역 만 11세 이상 전 연령대 520명(청소년: 250, 성인: 200, 어르신: 70)을 대상으로, 본검사는 서울, 경인지역 성인 642명(청소년: 280, 성인기: 214, 어르신: 148)을 대상으로 실시하였다. 분석은 SPSS와 facets 프로그램을 사용하였다. 검사내용에 기초한 증거로 개발된 신체활동 문항(청소년: 35, 성인: 34, 어르신: 24)의 탐색적요인분석 결과 요인적재치가 .4 이하인 문항(청소년: 19, 성인: 18, 어르신: 17)을 제거하고 최종 각 16, 16, 7문항으로 나타났다. 요인별로 Rasch 모형의 기본가정인 일차 원성을 검증하기 위해 주성분분석을 실시한 결과 요인별로 각 문항 모두 일차원성을 만족하였다. Rasch 모형 분석을 통한 문항적합도 분석 결과 청소년의 신체활동 요인에서 6문항이 내외적합지수(infit, outfit)가 부적합 문항이 나타났으며, 성인과 어르신은 문항적합도지수를 모두 만족하여 10, 16, 7문항으로 각 연령대별 신체활동척도를 개발하였다. The purposes of this study is to develop and validate the physical activity measurement scale (PAMS) for Korean females by age through goodness-of-fit in Rasch model. To improve reliability and validity, did separately accomplish pilot test(N=520)and real test(N=642). Based on the literature review and consultation of content and measurement experts, each 35, 34, 24 items PAMS was generated. The result was each 16, 16, 7-item which consists of factors(physical activity, will power, exercise intensity, exercise favor). The each item was analyzed through Exploratory Factor Analysis through SPSS program. Rasch measurement computer program, FACETS was used to analyze the data. Model data fit was determined by Infit and Outfit statistics(≥0.80 and ≤1.20). By age groups, each 10, 16, 7-item has good model data fit with acceptable fit statistics. Further, the 4 rating categories of each group functioned well with threshold advanced in category; separation reliability statistics provided evidence that the items had good variability. The 6 items of youth items were eliminated from estimation. This scale can be used to assess the physical activity requirements of individuals by aging and make use of result for korean female physical activity participants.

한국인의 건강보정 기대여명의 측정

강은정 ( Eun Jeong Kang ),윤석준 ( Seok Jun Yoon ),김나연 ( Na Yeon Kim ) 한국보건행정학회 2008 보건행정학회지 Vol.18 No.1

Summary measures of population health or SMPH is an index which can describe morbidity as well as mortality. Summary measures of population health can be divided into health-adjusted life years which is a life expectancy measure and disability-adjusted life years which represents the gap between the ideal health status and the current health status. This study aims at estimating health -adjusted life expectancy(HALE) which is a measure of health-adjusted life years, by calculating life expectancy adjusted by health status using EQ-5D. The mortality data was obtained from the life table of 2005 which was published by the National Statistical Office and the health status by sex and age was obtained from the EQ-5D scores using the third National Health and Nutrition and Examination Survey in 2005. With these mortality and morbidity data, health-adjusted life expectancy was calculated using Sullivan`s method. The study results showed that the health-adjusted life expectancy of males and females was 67.49 and 69.61, respectively, while the life expectancy of males and females was 75.14 and 81.89. In other words, Korean males and females lose 7.65 and 12.28, respectively, from the decrease of quality of life due to diseases and/or injuries. These results can further be interpreted that males lose 10.2% of their life expectancy and females 15.0%. This study suggests that it may be possible to monitor population`s health-adjusted life expectancy by continuing to include health-related quality of life measures such as EQ-5D in national health surveys like the National Health and Nutrition and Examination Survey.

EQ-5D를 이용한 건강수준의 가치 평가

강은정 ( Eun Jeong Kang ),신호성 ( Ho Sung Shin ),박혜자 ( Hye Ja Park ),조민우 ( Min Woo Jo ),김나연 ( Na Yun Kim ) 한국보건경제정책학회 2006 보건경제와 정책연구 Vol.12 No.2

As chronic conditions and life expectancy increase, there is a need of a comprehensive index of quality of life of individuals as well as mortality rate. Besides, the need for economic evaluations is being emphasized in order for the efficient use of the limited resources and for evidence-based public health policies. QALY which is used in cost-utility analysis is an important tool for evidence-based policies. In order to calculate QALY, we need value scores for various health status. EQ-5D which was included in the Korea National Health and Nutrition Survey in 2005 is one of the widely used health-related quality of life measures that are used in economic evaluations. The purpose of this study is to obtain value scores for the 243 health status of EQ-5D that are representative of Korea. This study covers the valuation of health status using the Korean version of EQ-5D and comparisons with the results from similar studies in foreign countries such as U.K., Japan, U.S., etc. We evaluated 17 status out of the 243 status of EQ-5D by time trade-off method. The final sample included 287 individuals. We could obtain a value set for the 243 health status from two random effect models which resulted in the identical value set. The value set comprised of logically consistent and valid 243 value scores. The two random effect models were different from current available foreign models. The study results can be used in cost-utility analyses in the future.

대장암의 효용 가중치에 영향을 미치는 요인

강은정 ( Eun Jeong Kang ),이재희 ( Jae Hee Lee ),정혜연 ( Hae Yeon Jeong ) 한국보건경제정책학회 2011 보건경제와 정책연구 Vol.17 No.4

Published utilities for the same health condition vary across studies. We investigated the factors related to utilities using the case of colorectal cancer for which we ran a meta-regression on the utilities of colorectal cancer derived from the relevant literature. We searched the literature published until December, 2010 in Medline, Science Direct, CINAHL, EMBASE, and KoreaMed from which 88 studies were selected. Among the 88 studies, we finally chose 16 studies from which 228 utility scores were retrieved to be included in the meta-regression. For each of the 228 utilities, information was recorded on its cancer stage, cancer type, cancer treatment, adverse reaction, remission, definition of the lower bound, definition of the upper bound, respondent, preference elicitation method, source of utility, and survey method. Fixed effect model was used to control for the correlations within the same study. We found that in the case of colorectal cancer, utilities were affected by metastatic stage, the type of colorectal cancer, adjuvant therapies, colostomy, preference elicitation method, and respondent, which suggests that in practice we should be careful in choosing utilities for economic evaluations and clinical decisions because several characteristics of health condition and utility measurement methods may affect the level of utilities.

골반 후복막강에 발생한 신경초종 2례

강은정(Eun Jeoung Kang),안수현(Soo Hyeon Ahn),정철회(Chul Hoi Jeong),김우경(Woo Gyeong Kim),김기태(Ki Tae Kim),김현찬(Hyun Chan Kim) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.11

Schwannomas are benign nerve sheath tumors that can originate at any anatomic sites. These tumors are usually soitary, benign, and slow-growing masses attached to large nerve trunks. These tumors have been described as arising in the pelvic retroperitoneum. We present two cases of pelvic retroperitoneal Schwannomas with a brief review of literatures.

만성C형간염을 동반한 만성 신부전 환자에서 인터페론 치료후 발생한 간질성 폐렴

강은정 ( Eun Jung Kang ),김동균 ( Dong Kyun Kim ),전성란 ( Seong Ran Jeon ),최현숙 ( Hyun Sook Choi ),정승원 ( Soung Won Jeong ),장재영 ( Jae Young Jang ),이준성 ( Joon Seong Lee ),어수택 ( Soo Taek Uh ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.1

After 4-months of alpha interferon (IFN-α), a 64-year old woman with chronic hepatitis C developed a cough and dyspnea and showed diffuse infiltrative opacities on her chest X-ray. Her symptoms persisted after stopping the IFN-α therapy. Pulmonary function testing revealed a reduced forced vital capacity. High-resolution computed tomography of the lung showed peripheral and peribronchovascular ground glass attenuation and consolidation associated with reticulation. Bronchoalveolar lavage was performed for further evaluation and showed a lymphocyte level of 8.2%, an uncommon finding in IFN-α-induced interstitial pneumonitis. We performed a lung biopsy to diagnose her disease and it suggested interstitial pneumonitis. This was considered to be due to the immunomodulatory effects of INF-α. Although rare, any sign of significant pulmonary involvement should be evaluated. (Korean J Gastroenterol 2011;58:47-52)