2013년 한국프랜차이즈만족지수(KS-FSI) 조사 및 결과 발표

박유경 한국유통학회 2013 한국유통학회 학술대회 발표논문집 Vol.2013 No.11

영어권 한국어 학습자의 척도 함축 해석에 대한 실험 연구

박유경,김영은 연세대학교 언어정보연구원 2022 언어사실과 관점 Vol.55 No.-

This study aims to explore second language acquisition of the scalar implicatureby English-speaking learners of Korean. To this end, we designed two scalarimplicature tasks in Korean and English. Experiment 1 provided a sentenceevaluation task with no context classified in terms of informational strength andfelicity. In Experiment 2, the participants were asked to determine the felicity oftarget sentences with scalar or logical reading in a given context that triggersscalar interpretation. In both experiments we analyzed the acceptance rate onscalar implicatures and found that there was a difference in the acceptance ratebetween native Koreans and English learners of Korean. This indicates the scalarinterpretation in L2 processing is more effortful than in one’s native language. We found that the experimental methods between Experiment 1 and 2 did notaffect the results. In both experiments, the acceptance rate on scalar interpretationby L2 learners was lower than by L1 speakers. We also found that the acceptancerate varies depending on lexical items: For example, both ‘myechmyech’ and‘etten’ correspond to English ‘some’, but the acceptance rate on scalarinterpretation with ‘myechmyech’ was higher than the acceptance rate with‘etten’. This suggests that we need to closely examine the semantic properties ofthe lexical items that seemingly have one-to-one correspondences between L1 andL2. The results in this study support the claim that the processing of scalarimplicature is effortful, so L2 learners have difficulty interpreting sentences withscalar items. .

고령의 만성 C형 간염 환자에서 Daclatasvir와 Asunaprevir 병용 요법의 유효성 및 안전성 평가

박유경,신수진,최유옥,최혜정,강진숙,황보신이 한국병원약사회 2018 病院藥師會誌 Vol.35 No.4

Background : The prevalence of chronic hepatitis C virus (HCV) tends to be higher in the elderly. Pegylated interferon and ribavirin therapy (Peg-IFN/RBV) was recommended as the first-line treatment in the past decades, but this regimen showed unsatisfactory results in terms of safety and efficacy especially in elderly patients. Recently, it was demonstrated that dual therapy with daclatasvir and asunaprevir was well tolerated and led to high sustained virological response (SVR) rates, irrespective of age. We conducted a study to evaluate the efficacy and safety of daclatasvir plus asunaprevir by involving elderly patients aged above 65 years. Methods : We retrospectively analyzed clinical data from chronic hepatitis C virus (HCV) genotype 1b patients treated with daclatasvir plus asunaprevir from September 2015 to December 2016 at Seoul St. Mary’s hospital. The patients were divided into two groups as elderly patients (older than 65 years) and non-elderly patients (younger than 65 years) and compared the efficacy and safety. Results : A total of 112 patients were treated with daclatasvir plus asunaprevir for chronic hepatitis C. Among them, 101 patients completed the whole treatment, and in 88 patients the amount of HCV RNA was measured after 12 weeks of treatment. There was no significant difference in SVR at 12 weeks between both the groups (p=0.68). Typically, 91.4%(32/35) of elderly patients and 94.3%(50/53) of nonelderly patients achieved SVR12. Common adverse events included elevation in transaminase level, headache, and gastrointestinal disorders. There was no statistical difference in the symptoms between the two groups. Conclusions : The combination therapy with daclatasvir plus asunaprevir exhibited similar rates of SVR12 in HCV elderly patients without leading to further adverse events compared to non-elderly patients. Therefore, it is proposed that daclatasvir plus asunaprevir therapy could be considered as an effective and safe treatment, even in patients aged over 65 years.

반응표면법에 의한 Lactiplantibacillus plantarum K79를 이용한 ACE(Angiotensin Converting Enzyme) 억제활성 향상을 위한 탈지유 발효조건 최적화

박유경,홍상필,임상동 한국낙농식품응용생물학회 2022 Journal of Dairy Science and Biotechnology (JMSB) Vol.40 No.3

This study was conducted using response surface methodology (RSM) to elucidate fermentation conditions that will optimize ACE inhibitory activity using Lactiplantibacillus plantarum K79. Four independent variables [skim milk (with 1% added glucose) concentration (6%– 14%), incubation temperature (32℃–42℃), incubation time (8–24 h), and amount of added starter (0.02%–0.2%)] were evaluated using five-level central composite design and response surface methodology to determine the optimum fermentation condition. The dependent variables were angiotensin converting enzyme (ACE) inhibitory activity (the value obtained from 102 diluted supernatant), and pH. The respective coefficients of determinations (R 2 ) were 0.791 and 0.905 for ACE inhibitory activity and pH. The maximum ACE inhibitory activity was 90% under the following conditions: 10% skim milk (with 1% added glucose) concentration, 37℃ incubation temperature, 17.8 h incubation time, and 0.2% added starter. Based on the RSM, using predicted best ACE conditions for fermentation of 13.49% skim milk (with 1% added glucose) with 0.0578% starter at 33.4℃ for 21.5 h, the predicted ACE inhibitory activity and pH values were 86.69% and 4.6, respectively. Actual ACE inhibitory activity and pH values were 85.5% and 4.58, respectively.

중국의 유료 미디어 플랫폼의 경쟁 상황과 방송의 통신 진출

박유경 한국방송학회 2019 한국방송학회 학술대회 논문집 Vol.2019 No.4

Comet Assay를 이용한 Flavonoids와 항산화 비타민의 인체임파구 세포 DNA 손상 보호 효과

박유경(Park Yoo Kyoung),전은재(Jeon Eun-Jae),강명희(Kang Myung-Hee) 韓國營養學會 2003 Journal of Nutrition and Health Vol.36 No.2

Letter to the Editor

박유경 대한골다공증학회 2017 Osteoporosis and Sarcopenia Vol.3 No.1

Ohta and his colleagues recently published a review of calcium and vitamin D in Asians, especially in Japan, which seems to be very timely [1]. In this paper, they showed that calcium intake in Japanese gradually increased from 1943 to 2007, and then while the intake in men did not show much of a decrease, calcium intake of women has been decreasing down to 500 mg/day or less since 2007, when the concern about the metabolic syndrome began. The authors also related these phenomena with a significant decline of body weight in women. In addition, the authors cited a paper published by Korean researchers [2] pointing out that calcium deficiency was greatly associated with secondary hyperparathyroidism and low bone mineral density. Based on this research and others [3] the authors claim that efforts should be made to increase calcium intake. I strongly agree that an effort to increase calcium intake is very urgent in Asian population, but I think that applying the study results [2] to the whole female population is a bit premature, as it is the result of study using only population over 50 years of age. Additional concerns for Japanese women as well as other Asian women are mentioned by authors that the calcium intake of Asian women never reached the recommended intake, and most of the calcium consumed is from vegetable source with lower bioavailability. Therefore, the authors suggested calcium supplementation. Vitamin D intake, a nutrient important for bone health as much as calcium, has always been difficult to investigate because of the lack of sufficient nutrient database and because vitamin D can be synthesized within the body. Nutritional status of vitamin D is therefore mainly estimated by using 25-hydroxyvitamin D concentration in blood. It is unfortunate that the authors could not provide national data of vitamin D level in this manuscript and therefore they could only speculate that sufficient calcium to be essential to prevent the loss of vitamin D action and protect bone loss. Nevertheless, the author clearly showed that Asian population are calcium deficient and encouragement to increase calcium, especially from dairy source is essential. Also increasing vitamin D intake, participation in outdoor activities for increase synthesis and even strategic management of vitamin D in the food supply may be needed for measurable benefits.

Soft X-ray spectroscopic study on the electronic structure of WO3 thin films fabricated under various annealing temperature and gas flow conditions

박유경,임창진,임영지,조수행,조상완,이현복,Ogasawara Hirohito 한국물리학회 2021 Current Applied Physics Vol.21 No.-

The electrical properties of WO3 thin films vary significantly depending on the growth conditions. In this work, the influence of O2 gas on the band gap of WO3 thin films during growth was investigated via electronic structure characterization using X-ray photoelectron spectroscopy (XPS), X-ray absorption spectroscopy (XAS), and X-ray emission spectroscopy (XES). A substantial decrease in the electrical conductivity of the WO3 films was observed with an increase in the O2 partial pressure during growth. Spectral differences in the peak energy and intensity were apparent for WO3 films grown under only Ar and those grown in Ar:O2. It is difficult to explain the acquired spectrum of WO3 with oxygen defects through the rigid-band model in terms of the simple addition of electrons to the conduction band of WO3. Our results show that an oxygen deficiency in WO3 moves the conduction band to the Fermi edge.

연극에 사용되는 색채에 관한 연구 : 연극<세상에서 가장 아름다운 이별>을 중심으로

박유경,안종숙,이민호 코리아뷰티디자인학회 2011 코리아뷰티디자인학회지 Vol.7 No.1

Practice Preferences on Dabigatran and Rivaroxaban for Stroke Prevention in Patients with Non-valvular Atrial Fibrillation

박유경,이정연,강지은,김승준,라현오 한국임상약학회 2016 한국임상약학회지 Vol.26 No.3

Objective: Prescription rate of dabigatran and rivaroxaban, which are the direct oral anticoagulants (DOAC), has increased. We have analyzed the prescription trend and medication use of dabigatran and rivaroxaban in patients with non-valvular atrial fibrillation (NVAF). Methods: It was retrospectively studied from September 2012 to April 2014 using the electronic medical records and the progress notes. Patients with NVAF (n=424) were evaluated on the medication use, prescribing preferences, adverse drug reactions (ADRs) and the availability of prescription reimbursement of dabigatran (n=210) and rivaroxaban (n=214). Results: Dabigatran was prescribed higher than rivaroxaban (23.3% versus 7.5%, p<0.001) in the neurology department, but rivaroxaban was prescribed higher compared to dabigatran in the cardiology department (87.4% versus 74.3%, p<0.001). Dabigatran was prescribed more than rivaroxaban in high risk patients with CHADS2 score ≥ 3 (44.3% versus 31.3%, p=0.006). Dabigatran patients seemed to have more ADRs than patients with rivaroxaban (25.2% versus 11.2%, p<0.001), but no serious thrombotic events and bleeding were found. Only 35.6% (n=151) were eligible for prescription reimbursement by the National Health Insurance (NHI). Bridging therapy (86, 31.5%) and direct-current cardioversion (57, 20.2%) were main reasons of ineligibility for reimbursement. Conclusion: Prescription preferences were present in choosing either dabigatran or rivaroxaban for patients with NVAF. Inpatient protocols and procedures considering patient-factors in NVAF need to be developed.