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金淇燮,沈舜植 慶尙大學校 1981 論文集 Vol.20 No.2
Koreans mispronounce English words by the misapplication of Korean Phonological Rules to English words. Among the mispronunciations of them those by the misapplication of Korean Nasalization Rule is typical. The present study attempts to clarify the rule ordering of Korean Nasalization Rule through analysis and interpretation of the phenomena shown in the mispronunciation of English words. Many Korean Phonologists like Hur, C. W. Kim, Kim Renaud argue that n-lateralization Rule: n→1% 1 is phonitic and natural and obligatory, while/??/to [??] is sometimes made through analogy (which argumentation is slightly dealt by Hur.) In this study the efforts are made to prove that 1→n/n is no less natural than 1→n/??-. The naturalness and plausibility of Nasalization, 1→n/n- in Korean is studied, analyzed and interpreted from the view-point of, 1) Hyman's argumentation of 'ease of articulation': [+lat] after/n/is to be easily assimilated to [n] which had the same distinctive features [+ant], [+cor] that the preceding/n/has, just as after/m/or/??/, 2) Surface Phonetic Constraints by Shibatanni and other phonologists that in word initial or after consonant Sino-Korean/1/is changed to [n]: 1←n/??#-, and, 3) Stampe's argumentation of processes and rules in his Natural Phonology, Accordingly in 1-Nasalization Rule argued by many phonologists is 1→n/n-coucluded to be included, while so far they have only regarded 1→n/??#- as not occurring in case of C being n. Therefore, rule ordering of Korean Nasalization should be made: n-Lateralization 1-Nasalization(where SPC 1→n/n-should be added) Plosivization Stop Nasalization with both examples given in mispronunciations of English words and those in Korean. However, those examples in Korean should be words of free morphemes, but not of bound ones. In the end, comparison of English words with i-Epenthesis in English words makes a serous suggestion that the latter lets Koreans commit fewer errors in pronunciation of English words as shown in 'hopeless' : 3 errors by 3 factors p→m, 1→n, i-Epentiesis in/houpilisi/to [houmnisi] vs. 2 by only one factor i-Epenthesis in/houplis/to [houpillsi].
Carrier-Adjuvant로써 Cholera Toxin을 사용한 항 Fumonisin 항체생산과 이를 이용한 ELISA 개발
정순관(Soon Kwan Chung),이문한(Mun Han Lee),이항(Hang Lee),류판동(Pan Dong Ryu),조명행(Myung Haing Chio),이영재(Young Jae Lee),이혜숙(Hye Sook Lee),박종명(Jong Myung Park),심영화(Young Hwa Sim),김재명(Jae Myung Kim),임종섭(Jong Seop 한국예방수의학회 1995 예방수의학회지 Vol.19 No.4
Murine polyclonal antibody reactive with fumonisin B₁(FB₁) was produced by immunization with FB₁-cholera toxin(CT) conjugate as a carrier-adjuvant and an emzyme-linked immunosorbent assay (ELISA) was developed to detect fumonisin in feedstuffs. The immunogen, FB₁-CT, and coating antigen, FB₁-ovalbumin(OA), were prepared by coupling FB₁ to CT or OA with 2% glutaraldehyde. Mice were immunized by injecting FB₁-CT conjugate intraperitonially 3 times on 14 day intervals and a large volume of ascites containing antibody to fumonisins was produced by injecting pristane and myelorna cells into peritonium. Antibody titers were measured by indirect ELISA after each immunization and antibody in ascites was partially purified by ammonium sulfate precipitation and gel filtration. A standard curve of FB₁(n=8) was aquired by competitive indirect ELISA using the partially purified ascitic antibody and FB₁-OA as a coating antigen, and the standard curve showed that the lowest detection limit of FB₁ is 100ng/mL level(p<0.01). The ascitic antibody cross-reacted with FB₂(97%), but no cross-reactivities were observed with tricarballylic acid, aflatoxins(B₁, B₂, G₁, and G₂), zearalenone, T-2 toxin, and ochratoxin A Competitive ELISA curves in the presence of organic solvents used to extract FB₁ from feedstuffs showed that the concentrations of organic solvents up to 18.5% methanol and 12.5% acetonitrile had no prominent effects on the ELISA system developed, suggesting that the diluted organic solvent extract of the sample may be used for the ELISA without solvent evaporation. When FB₁ from spiked corns was extracted with 50% acetontrile and subjected to the ELISA after the concentration of acetonitrile was reduced to 12.5% by dilution with PBS, the recovery rates of FB₁ in corns containing 1, 2.5 and 5 μg/g of FB₁ were 194%, 107% and 82.1%, respectively. Therefore, the ELISA system developed in this study using the polyclonal antibody to FB1 could be applied to determine fumonisins in feedstuffs.
프리캐스트 콘크리트 부재의 평탄도 검사를 위한 센싱 기반 측정방법 적합도 비교
권순호,김정섭,심성한,김민구,Kwon, Soon-Ho,Kim, Jeong Seop,Sim, Sung-Han,Kim, Minkoo 한국건설관리학회 2023 한국건설관리학회 논문집 Vol.24 No.4
Flatness inspection of PC elements is normally conducted manually by inspectors at manufacturing sites. However, the manual inspection is error-prone and subjective, so it is necessary to develop a robust and efficient flatness measurement method. Recently, a few studies of laser scanner-based flatness inspection have been conducted. However, little attention on field applicability in terms of accuracy, time and cost has been paid. To tackle the limitation, this study aims to compare three sensing method including floor profiler, terrestrial laser scanner and total station for flatness inspection of PC elements. A series of experiments on two full-scale PC slabs were conducted and the results show that the laser scanning method is the most suitable for the PC elements flatness inspection in the aspects of accuracy, time and cost.
Evaluation of Irritating Potential of Newly Developed Toothpaste in the Hamster Oral Mucous Membrane
Bae-Hwan Kim,Jin-Woo Kim,Ih-Seop Chang,Young-Chul Sim,Yong-Soon Lee 한국독성학회 2001 Toxicological Research Vol.17 No.3
Oral mucous membrane test using Syrian hamsters was performed to evaluate the reliability as a model system for the assessment of the potentially irritating substances intended for the mucous membranes, and to determine the irritating potential of a new emulsion-type formulated toothpaste. After test substances were implanted into the cheek pouches of hamsters with diluents (20mg/Kg) under pentobarbital sodium anesthesia, we made the comparison in irritation between emulsion-type and dispersion-type of triclosan (TCS) formulations in the range of 0.2% to 0.3%. The emulsion-type formulations using non-ionic surfactant showed less mucosal lesion than other commercial toothpastes with 0.3% TCS, or dispersion-type ones. However, no significant difference in irritation was detected between 0.2% and 0.3% TCS. We report that this hamster cheek pouch method could be a reliable approach for the evaluation of slight difference in the irritation potentials of cosmetics and hygiene products intended for the lips or other mucous membranes, and this method showed that the new emulsion-type formulation significantly lowered the TCS-induced toxicity, compared with other commercial toothpastes.
Evaluation of Irritating Potential of Newly Developed Toothpaste in the Hamster Oral Mucous Membrane
Kim, Bae-Hwan,Kim, Jin-Woo,Chang, Ih-Seop,Sim, Young-Chul,Lee, Yong-Soon Korean Society of ToxicologyKorea Environmental Mu 2001 Toxicological Research Vol.17 No.3
Oral mucous membrane test using Syrian hamsters was performed to evaluate the reliability as a model system for the assessment of the potentially irritating substances intended for the mucous membranes, and to determine the irritating potential of a new emulsion-type formulated toothpaste. After test substances were implanted into the cheek pouches of hamsters with diluents (20 mg/kg) under pento-barbital sodium anesthesia, we made the comparison in irritation between emulsion-type and dispersion-type of triclosan (TCS) formulations in the range of 0.2% to 0.3%. The emulsion-type formulations using non-ionic surfactant showed less mucosal lesion than other commercial toothpastes with 0.3% TCS, or dispersion-type ones. However, no significant difference in irritation was detected between 0.2% and 0.3% TCS. We report that this hamster cheek pouch method could be a reliable approach for the evaluation slight difference in the irritating potentials of cosmetics and hygiene products intended for the lips or other mucous membranes, and this method showed that the new emulsion-type formulation significantly lowered the TCS-induced toxicity, compared with other commercial toothpastes.
( Eunhye Cho ),( Sung Yob Kim ),( Chul Min Park ),( Soon Seop Sim ),( Hae Sim Kang ),( Soyun Park ),( Soo Jung Kim ),( Seong-cheol Hong ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Objective: There is few studies compared standard abdominal sacrocolpexy and the laparoscopic approach for POP patient with uterus. We aim to compare the therapeutic effect of laparoscopic and abdominal sacrocolpopexy . Methods: We performed retrospective study comparing abdominal sacrocolpopexy and laparoscopic sacrocolpopexy in single university hospital in Jeju island, South Korea. We collected sacrocolpopexy surgery case from July 2008 to December 2017. Total number of case was 183 and we selected 120 cases performed by single operator. Among them, we excluded vault prolapse and total 105case were compared. Because all of the cases were performed by single operator, pre-operative and post-operative treatment were almost same through whole case. The collected data was analyzed by using statistics package SPSS version 2. Results: The characteristics of patients were almost same between the two group. Parity was the only different parameter. But it may affect pre-op POP stage or severity of disease, so we didnt give meaning. Estimated blood loss during the operation was smaller and operation time was shorter in the laparoscopic sacrocolpopexy group. Number of complication was indifferent between two group. Conclusion: Our trial provides evidence to support a laparoscopic approach when performing sacrocolpopexy, as there was less blood loss and operation time was shorter, whereas complication was not statistically different. A strength of this study is that whole perioperative care was identically done for all patient.