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SOME BEST PROXIMITY POINT RESULTS OF SEVERAL α-ψ INTERPOLATIVE PROXIMAL CONTRACTIONS
Jia Deng,Xiao-lan Liu,Yan Sun,Laxmi Rathour 경남대학교 수학교육과 2022 Nonlinear Functional Analysis and Applications Vol.27 No.3
In this paper, we introduce several types α-ψ interpolative proximal contractions and provide some sfficient conditions to prove the existence of best proximity points for these contractions in metric spaces. In the case of proximal contraction of the first kind, these metric spaces are not necessarily complete. Meanwhile, some new results can derive from our results. Finally, some examples are provided to show the validity of our results.
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Deng, Wei,Long, Long,Li, Ji-Lin,Zheng, Dan,Yu, Jia-Hua,Zhang, Chun-Yan,Li, Ke-Zhi,Liu, Hai-Zhou,Huang, Tian-Ren Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4
The incidence and mortality rates of liver and nasopharyngeal cancer in Guangxi province of China have always been among the highest in the world, and cancer is one of the major diseases that pose a threat to the health of residents in Guangxi. However, no systematic study has been performed to evaluate the time trends in the structure of cancer-related deaths and cancer mortality. In this study, we reveal sex, age and geography differences of cancers mortality between three death surveys (1971 to 1973, 1990 to 1992, and 2004 to 2005). The results show that the standardized mortality rate of cancer in Guangxi residents has risen from 43.3/100,000 to 84.2/100,000, the share of cancer deaths in all-cause deaths has increased from 13.3% to 20.7%, and cancer has become the second most common cause of death. The five major cancers, liver cancer, lung cancer, gastric cancer, nasopharyngeal cancer and colorectal cancer, account for 60% of all the cancer deaths. Cancers with growing mortality rates over the past 30 years include lung cancer, colorectal cancer, liver cancer and female breast cancer, of which lung cancer is associated with the sharpest rise in mortality, with a more than 600% rise in both men and women. Cancer death in Guangxi residents occurs mainly in the elderly population above 45 years of age, especially in people over the age of 65. The areas with the highest mortality rates for liver cancer and nasopharyngeal cancer, which feature regional high incidences, include Chongzuo and Wuzhou. Therefore, for major cancers such as liver cancer, lung cancer, gastric cancer, nasopharyngeal cancer and female breast cancer in Guangxi, we can select high-risk age groups as the target population for cancer prevention and control efforts in high-prevalence areas in a bid to achieve the ultimate goal of lowering cancer mortality in Guangxi.
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( Deng-fong Lin ),( Huan-lin Luo ),( Wei-zhu Wang ),( Jia-wen Chen ) 한국폐기물자원순환학회(구 한국폐기물학회) 2019 ISSE 초록집 Vol.2019 No.-
The bottom ash (BA) is the residuals of the municipal trashes after incinerated in an incinerator plant. The BA is usually collected and landfilled as the final disposal treatment. However, it becomes harder finding locations for Taiwan as an island with a very scarce land for the landfill treatment. Moreover, the amount of the BA recycled was far behind the amount produced in which leading to a hard problem for central and local governments. How to properly recycle or reuse of the BA becomes an urgent need. From the results obtained by many different researchers, the use of the BA as a ceramic material may help improve the strength of related products. In this study, the BA was applied as part of the replacement for kaolin in the manufacture of the brick specimens. To investigate the effects of the kiln temperature on the brick specimens and evaluate the related properties of the specimens, the kiln temperatures were set at 850, 900, and 950℃. The municipal solid waste incineration BA was applied as part of kaolin replacement in the manufacture of bricks. Test results showed that the shrinkage increment of bricks tended to be smooth when the BA replacement was larger than 10%. Moreover, the results of loss on ignition indicated that the organic and inorganic matters and heavy metal were mostly burned off at the kiln temperature of 900℃ or above. The compressive strengths of bricks increased with the increase amount of BA replacement. The study of the micro structure observations showed that the silicification of the brick specimen bodies reduced with the increase amount of the BA replacement. Moreover, the results obtained from XRD indicated that the peak intensities of the SiO<sub>2</sub> in the brick specimens decreased with increase amount of the BA replacement. This study suggested that the optimal amount of BA replacement and the kiln temperature were 20% and 950℃, respectively.
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Inhibition of acetylation of histones 3 and 4 attenuates aortic valve calcification
Jia Gu,Yan Lu,Menqing Deng,Ming Qiu,Yunfan Tian,Yue Ji,Pengyu Zong,Yongfeng Shao,Rui Zheng,Bin Zhou,Xiangqing Kong,Wei Sun 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-
Aortic valve calcification develops in patients with chronic kidney disease who have calcium and phosphate metabolic disorders and poor prognoses. There is no effective treatment except valve replacement. However, metabolic disorders put patients at high risk for surgery. Increased acetylation of histones 3 and 4 is present in interstitial cells from human calcific aortic valves, but whether it is involved in aortic valve calcification has not been studied. In this study, we found that treating cultured porcine aortic valve interstitial cells with a high-calcium/high-phosphate medium induced calcium deposition, apoptosis, and expression of osteogenic marker genes, producing a phenotype resembling valve calcification in vivo. These phenotypic changes were attenuated by the histone acetyltransferase inhibitor C646. C646 treatment increased the levels of class I histone deacetylase members and decreased the acetylation of histones 3 and 4 induced by the high-calcium/high-phosphate treatment. Conversely, the histone deacetylase inhibitor suberoylanilide hydroxamic acid promoted valve interstitial cell calcification. In a mouse model of aortic valve calcification induced by adenine and vitamin D treatment, the levels of acetylated histones 3 and 4 were increased in the calcified aortic valves. Treatment of the models with C646 attenuated aortic valve calcification by restoring the levels of acetylated histones 3 and 4. These observations suggest that increased acetylation of histones 3 and 4 is part of the pathogenesis of aortic valve calcification associated with calcium and phosphate metabolic disorders. Targeting acetylated histones 3 and 4 may be a potential therapy for inoperable aortic valve calcification in chronic kidney disease patients.
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Jia Long,Zixu Miao,Huihuang Chen,Rongdong Deng,Weiran Zuo,Bao Guo,Jiangang Ku 한국자기학회 2020 Journal of Magnetics Vol.25 No.1
Chain-like and diamond-shaped magnetic particle agglomeration (MPA) commonly forming in a weak magnetic field are simulated based on the finite element method (FEM), and the effects of particle diameter, magnetic field strength, particle relative magnetic permeability, and particle number in magnetic particle chains (MPCs) and diamond-shaped MPA on the strength of MPA are analysed in detail. The results show that magnetic forces on the centre contact points (CCPs) of MPA are positively correlated with the particle diameter, magnetic field strength, particle relative magnetic permeability, and particle number. In addition, the forces on the CCPs of the MPCs (N=2) have a square relationship with the particle diameter and magnetic field strength and have a power relationship of 1.25 with the particle relative magnetic permeability. The forces on each contact point decrease slowly from the centre to both ends in the MPCs and then rapidly decrease to one value (approximately 0.779 times the forces on the CCPs). As for the diamond-shaped MPA, with the increase in the angle α between the magnetic field and axis of diamond-shaped MPA, the force magnitude of the particle entrained parallelly in the diamond-shaped MPA shows a trend of a “cosine curve” shape and the minimum value is 2109 times that of the entrained particle’s gravity. The angle θ between the direction of the force and the negative X-axis shows a trend of a “sine curve” shape. When α = 25° and 155°, the angle θ of the force on the entrained particle reaches an extreme value, that is, θ = 21.87°. Only if the angle θ reaches 30º can the particle entrained parallelly escape from the diamond-shaped MPA. Thus, the diamond-shaped MPA remains in a stable state and it is difficult to disperse MPA by changing the direction of the magnetic field.
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Li Deng,Wenpeng Jia,Wen Zheng,Hao Liu,Degang Jiang,Zimeng Li,Yu Tian,Wenling Zhang,Jingquan Liu 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.58 No.-
Ni–Al layered double hydroxides (Ni–Al LDHs) are adopted as an electrorheological (ER) materialascribed to their special layered structure, ample polarizable groups and good dispersibility. Themagnetite nanoparticles (Fe3O4 NPs) are utilized as classical magnetorheological (MR) materials onaccount of their excellent paramagnetic property. In this work, we report the rational design of highperformanceER/MR materials by integrating the structural merits of Fe3O4 NPs onto a binary layeredstructure system. The obtained Fe3O4/Ni–Al LDH NCs dispersed in silicone oil displayed appealing dualER/MR performances. The work opens a new path toward novel stimuli-responsive materials forindustrial applications.
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Manjing Deng,Qian Xu,Zhihua Liu1,Ling Guo,Rui Liu,Rulei Li,Xiang Chu,Jiajia Yang,Jia Luo,Faming Chen 한국분자세포생물학회 2019 Molecules and cells Vol.42 No.11
Periodontitis is characterized by the loss of periodontal tissues, especially alveolar bone. Common therapies cannot satisfactorily recover lost alveolar bone. Periodontal ligament stem cells (PDLSCs) possess the capacity of self-renewal and multilineage differentiation and are likely to recover lost alveolar bone. In addition, periodontitis is accompanied by hypoxia, and hypoxia-inducible factor-1α (HIF-1α) is a master transcription factor in the response to hypoxia. Thus, we aimed to ascertain how hypoxia affects runt-related transcription factor 2 (RUNX2), a key osteogenic marker, in the osteogenesis of PDLSCs. In this study, we found that hypoxia enhanced the protein expression of HIF-1α, vascular endothelial growth factor (VEGF), and RUNX2 ex vivo and in situ. VEGF is a target gene of HIF-1α, and the increased expression of VEGF and RUNX2 proteins was enhanced by cobalt chloride (CoCl2, 100 μmol/L), an agonist of HIF-1α, and suppressed by 3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole (YC-1, 10 μmol/L), an antagonist of HIF-1α. In addition, VEGF could regulate the expression of RUNX2, as RUNX2 expression was enhanced by human VEGF (hVEGF165) and suppressed by VEGF siRNA. In addition, knocking down VEGF could decrease the expression of osteogenesis-related genes, i.e., RUNX2, alkaline phosphatase (ALP), and type I collagen (COL1), and hypoxia could enhance the expression of ALP, COL1, and osteocalcin (OCN) in the early stage of osteogenesis of PDLSCs. Taken together, our results showed that hypoxia could mediate the expression of RUNX2 in PDLSCs via HIF-1α-induced VEGF and play a positive role in the early stage of osteogenesis of PDLSCs
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Xinping Jia,Yanming Deng,Xiaobo Sun,Lijian Liang,Xiaoqing Ye 한국유전학회 2015 Genes & Genomics Vol.37 No.1
Seashore paspalum (Paspalum vaginatum O. Swartz) is a halophytic warm-season perennial grass,which plays an important role in protection of environment. However, very limited transcriptomic and genomic informationare currently available for seashore paspalum. Inthis study, the seashore paspalum transcriptome weresequenced using Illumina paired-end sequencing technology. In total, 32,603 unigenes with an average length of970 bp were obtained by de novo assembly. Of the unigenes,25,411 unigenes (77.94 %) had significant similaritywith known proteins in the NCBI non-redundant proteinand Swiss-Prot databases. Of these annotated unigenes,20,962 and 10,620 unigenes were assigned to gene ontologycategories and clusters of orthologous groups,respectively. A total of 4,699 unigenes were mapped into118 Kyoto Encyclopedia of Genes and Genomes pathways. In addition, 3,010 potential simple sequence repeats (SSRs)were predicted for microsatellite analyse. Tri-nucleotidewas the dominant repeat (1,583, 52.58 %), followed by dinucleotide(975, 32.39 %) and tetra-nucleotide (217,7.21 %). Fifty SSR sites were randomly selected for validationand development of EST–SSR markers. This studyprovided the global sequence data for seashore paspalumand demonstrated that the Illumina paired-end sequencingis a fast and cost-effective approach to gene discovery andmolecular marker development.
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