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      • KCI등재

        Collective dynamics in multi-population Hamiltonian systems

        Tian Jing,Ying Jiaqi,Qiao Tianli,Qiu Haibo 한국물리학회 2023 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.82 No.12

        In this paper, we investigate measure synchronization (MS) in a two-population network of coupled metronomes system. The system consists of N identical metronomes placed on two swing boards, and the two swings are connected by spring of stifness k. Metronomes on each swing represents a single population. We mainly study the collective dynamics of multipopulation Hamiltonian induced by increased couplings, including inter-population and intra-population couplings. It is found that by tuning K for the inter-population coupling intensity and R for the intra-population coupling intensity, the system reaches various MS states at certain critical coupling intensities, including partial MS and complete MS. The occurrence of partial and complete MS are discussed particularly by analyzing the Poincaré sections of the Hamiltonian system. In addition, we fnd correspondence in between the phase-locking dynamics and various MS transitions.

      • KCI등재

        Measure Synchronization in a Huygens’s Non-Dissipative Two-Pendulum Clocks System

        Jing Tian,ZiChen Chen,HaiBo Qiu,XiaoQiang Xi 한국물리학회 2018 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.72 No.2

        In this paper, we characterize measure synchronization (MS) in a four-degrees-of-freedom Huygens’s two-pendulum clocks system. The two-pendulum clocks are connected by a massless spring with stiffness constant k. We find that with the stiffness constant k increasing, the coupled pendulums system achieves MS above a threshold value of kc. The energy characteristics of measure synchronization have been discussed, it is found that averaged energy of each pendulum system provide us an easy way to characterize MS transition. Furthermore, we discuss the dependence of the critical value for MS transition on initial conditions and the characteristic parameters of the system.

      • KCI등재

        Measure Synchronization and Phase Coherence in a High Dimensional Hamiltonian System

        Jing Tian,Bo Li,Haibo Qiu 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.74 No.8

        Partial and complete measure synchronizations (MSs) are investigated in a high-dimensional Hamiltonian system. Here, a four-coupled ring-shaped rotor model is employed. We calculate the averaged energy of each rotor numerically to address the clustering process of measure synchronization. Poincar\'e sections are used to analyze the dynamic mechanism of partial MS and complete MS transitions, and the separatrix crossing is revealed to be the dynamical mechanism behind all different MS transition behaviors. By calculating the averaged frequency of each rotor, we explore the relationship between frequency locking and MS, and reveal a one-to-one correspondence. Furthermore, we find that abrupt changes in global or even partial phase coherence between the phase oscillators can be an indicator for MS transitions, albeit full phase coherence is not equivalent to measure synchronization.

      • SCIESCOPUSKCI등재

        Effect of Choice Feeding on Performance, Gastrointestinal Development and Feed Utilization of Broilers

        Yao, Junhu,Tian, Xiaoyan,Xi, Haibo,Han, Jincheng,Xu, Ming,Wu, Xiaobing Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.1

        The experiment was conducted to study the effect of choice feeding on growth performance, carcass quality, gastrointestinal development and feed utilization of 22-49 days old broilers. One hundred and forty four 22-day-old broilers were randomly allocated to 3 treatments with 4 replicates per treatment and 12 birds per replicate. Three feeding regimes are complete diet (control), ground corn and protein concentrate (treatment I), and soybean meal and balancer (treatment II). Protein concentrate is the residue part of complete diet without corn, and balancer is the residue part of complete diet without soybean meal. Treatment I and II are designed for the broilers to freely choose the two parts of diet. The results showed that: (1) broilers under choice feeding (treatment I and II) had lower performances compared with the control; (2) gastrointestinal development and the efficiency ratios that broilers converted dietary crude protein and lysine to body weight gain were improved in treatment I (p<0.05); (3) there were no significant differences in the apparent metabolizabilities of dietary dry matter, crude protein and gross energy, and deposition ratios of dietary nitrogen and energy, and carcass quality among three feeding regimes (p>0.05).

      • KCI등재

        How to retrieve the encrypted data on the blockchain

        ( Huige Li ),( Fangguo Zhang ),( Peiran Luo ),( Haibo Tian ),( Jiejie He ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.11

        Searchable symmetric encryption (SSE) scheme can perform search on encrypted data directly without revealing the plain data and keywords. At present, many constructive SSE schemes were proposed. However, they cannot really resist the malicious adversary, because it (i.e., the cloud server) may delete some important data. As a result, it is very likely that the returned search results are incorrect. In order to better guarantee the integrity of outsourcing data, and ensure the correction of returned search results at the same time, in this paper, we combine SSE with blockchain (BC), and propose a SSE-on-BC framework model. We then construct two concrete schemes based on the size of the data, which can better provide privacy protection and integrity verification for data. Lastly, we present their security and performance analyses, which show that they are secure and feasible.

      • KCI등재

        Modification of Wool via Grafting β-cyclodextrin Oxidized by Sodium Periodate

        Chaoqian Lou,Yuanyuan Yin,Xiuzhi Tian,Haibo Deng,Yingxia Wang,Xue Jiang 한국섬유공학회 2020 Fibers and polymers Vol.21 No.8

        The modification of wool fabrics is significant in preparation of functional textiles. Sodium periodate oxidized β-cyclodextrin was grafted onto wool fabric through Schiff base reaction to obtain fabric with controlled release property. β-cyclodextrin was oxidized to aldehyde-β-cyclodextrin, and the results show that the inclusion constant and aldehyde contentof aldehyde-β-cyclodextrin are varied with the reaction parameters such as molar ratio of reaction agents and the reactiontemperature. The degree of oxidation was confirmed by ion chromatography. The drug loading test shows that the oxidizedcyclodextrin still had inclusion ability towards phenolphthalein, while the inclusion constant was only 50 % of the original β-CD. The ATR-FTIR spectra proved the occurrence of grafting reaction between the aldehyde groups of aldehyde-β-cyclodextrin and the amino groups on wool fiber. The aldehyde-β-cyclodextrin grafted wool fabric show great washingdurability even after 5 washing cycles. Compared with the aldehyde-β-cyclodextrin power, the inclusion ability of aldehyde-β-cyclodextrin fixed on the wool fiber decreased by 60 %.

      • KCI등재

        Hydrophilic Finishing of PET Fabrics by Applying Chitosan and the Periodate Oxidized β-cyclodextrin for Wash Resistance Improvement

        Chaoqian Lou,Yuanyuan Yin,Xiuzhi Tian,Haibo Deng,Yingxia Wang,Xue Jiang 한국섬유공학회 2020 Fibers and polymers Vol.21 No.1

        β-cyclodextrin (β-CD) was oxidized by sodium periodate to yield a mixture of dialdehyde oligosaccharides. Theperiodate-oxidized β-CD (O-β-CD) together with chitosan (CTS) was firstly used to finish poly(ethylene terephthalate)(PET) fabrics by immersion-padding method, in which O-β-CD acted as a hydrophilic finishing agent plus a cross-linker. Theprocesses including the periodate oxidization of β-CD and the CTS/O-β-CD hydrophilic finishing of PET fabrics were ecofriendly. The results from the hydroxylamine hydrochloride titration showed that the aldehyde content in O-β-CD was3.0 mmol/g. With increasing the CTS/O-β-CD mass ratio, the finished fabric had better hydrophilic properties. When theCTS/O-β-CD mass ratio was 1:1, the moisture regain and water drops wetting time of the finished fabric reached 1.85 % and5.06 s, respectively. They became 1.50 % and 5.70 s, respectively after 25 times of laundering cycle. The occurrence of crosslinkingbetween O-β-CD and CTS was confirmed by the gel test and FT-IR characterization. The cross-linking networkdeposited on the fiber surface brought on excellent wash resistance of the CTS/O-β-CD finished PET fabrics.

      • New receipt-free voting scheme using double-trapdoor commitment

        Chen, Xiaofeng,Wu, Qianhong,Zhang, Fangguo,Tian, Haibo,Wei, Baodian,Lee, Byoungcheon,Lee, Hyunrok,Kim, Kwangjo Elsevier 2011 Information sciences Vol.181 No.8

        <P><B>Abstract</B></P><P>It is considered to be the most suitable solution for large scale elections to design an electronic voting scheme using blind signatures and anonymous channels. Based on this framework, Okamoto first proposed a receipt-free voting scheme <ce:cross-ref refid='b0150'>[30]</ce:cross-ref> for large scale elections. However, in the following paper, Okamoto <ce:cross-ref refid='b0155'>[31]</ce:cross-ref> proved that the scheme <ce:cross-ref refid='b0150'>[30]</ce:cross-ref> was not receipt-free and presented two improved schemes. One scheme requires the help of the parameter registration committee and the other needs a stronger physical assumption of the voting booth. In this paper, we utilize the double-trapdoor commitment to propose a new receipt-free voting scheme based on blind signatures for large scale elections. Neither the parameter registration committee nor the voting booth is required in our scheme. We also present a more efficient zero-knowledge proof for secret permutation. Therefore, our scheme is much more efficient than Okamoto’s schemes <ce:cross-refs refid='b0150 b0155'>[30,31]</ce:cross-refs> with the weaker physical assumptions. Moreover, we prove that our scheme can achieve the desired security properties.</P>

      • KCI등재

        The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes

        Liu Dan,Xing Ruinan,Zhang Quanyu,Tian Xiaoxiang,Qi Yanping,Song Haixu,Liu Yanxia,Yu Haibo,Zhang Xiaolin,Jing Quanmin,Yan Chenghui,Han Yaling 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        Autophagy plays an important role in the development of diabetic cardiomyopathy. Cellular repressor of E1A-stimulated genes 1 (CREG1) is an important myocardial protective factor. The aim of this study was to investigate the effects and mechanisms of CREG1 in diabetic cardiomyopathy. Male C57BL/6 J mice, Creg1 transgenic mice and cardiac-specific knockout mice were used to establish a type 2 diabetes model. Small animal ultrasound, Masson’s staining and western blotting were used to evaluate cardiac function, myocardial fibrosis and autophagy. Neonatal mouse cardiomyocytes (NMCMs) were stimulated with palmitate, and the effects of CREG1 on NMCMs autophagy were examined. CREG1 deficiency exacerbated cardiac dysfunction, cardiac hypertrophy and fibrosis in mice with diabetic cardiomyopathy, which was accompanied by exacerbated autophagy dysfunction. CREG1 overexpression improved cardiac function and ameliorated cardiac hypertrophy and fibrosis in diabetic cardiomyopathy by improving autophagy. CREG1 protein expression was decreased in palmitate-induced NMCMs. CREG1 knockdown exacerbated cardiomyocyte hypertrophy and inhibited autophagy. CREG1 overexpression inhibited cardiomyocyte hypertrophy and improved autophagy. LAMP2 overexpression reversed the effect of CREG1 knockdown on palmitate-induced inhibition of cardiomyocyte autophagy. CREG1 inhibited LAMP2 protein degradation by inhibiting the protein expression of F-box protein 27 (FBXO27). Our findings indicate new roles of CREG1 in the development of diabetic cardiomyopathy.

      • KCI등재

        CDH17 nanobodies facilitate rapid imaging of gastric cancer and efficient delivery of immunotoxin

        Jingbo Ma,Xiaolong Xu,Chunjin Fu,Peng Xia,Ming Tian,Liuhai Zheng,Kun Chen,Xiaolian Liu,Yilei Li,Le Yu,Qinchang Zhu,Yangyang Yu,Rongrong Fan,Haibo Jiang,Zhifen Li,Chuanbin Yang,Chengchao Xu,Ying Long,J 한국생체재료학회 2022 생체재료학회지 Vol.26 No.4

        Background: It is highly desirable to develop new therapeutic strategies for gastric cancer given the low survival rate despite improvement in the past decades. Cadherin 17 (CDH17) is a membrane protein highly expressed in cancers of digestive system. Nanobody represents a novel antibody format for cancer targeted imaging and drug delivery. Nanobody targeting CHD17 as an imaging probe and a delivery vehicle of toxin remains to be explored for its theragnostic potential in gastric cancer. Methods: Naïve nanobody phage library was screened against CDH17 Domain 1-3 and identified nanobodies were extensively characterized with various assays. Nanobodies labeled with imaging probe were tested in vitro and in vivo for gastric cancer detection. A CDH17 Nanobody fused with toxin PE38 was evaluated for gastric cancer inhibition in vitro and in vivo. Results: Two nanobodies (A1 and E8) against human CDH17 with high affinity and high specificity were successfully obtained. These nanobodies could specifically bind to CDH17 protein and CDH17-positive gastric cancer cells. E8 nanobody as a lead was extensively determined for tumor imaging and drug delivery. It could efficiently co-localize with CDH17-positive gastric cancer cells in zebrafish embryos and rapidly visualize the tumor mass in mice within 3 h when conjugated with imaging dyes. E8 nanobody fused with toxin PE38 showed excellent anti-tumor effect and remarkably improved the mice survival in cell-derived (CDX) and patient-derived xenograft (PDX) models. The immunotoxin also enhanced the anti-tumor effect of clinical drug 5-Fluorouracil. Conclusions: The study presents a novel imaging and drug delivery strategy by targeting CDH17. CDH17 nanobodybased immunotoxin is potentially a promising therapeutic modality for clinical translation against gastric cancer.

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