Coagulant와 Hydro-cyclone을 결합한 상향류식 여과시스템

김명호,고대현,정다래,이준호 한국교통대학교 2021 한국교통대학교 논문집 Vol.56 No.-

Coagulation Hydro-cyclone can be added to the upward flow filtration system utilizing Fiber-Ball filter media to analyze and evaluate the treatment characteristics in order to Non-point pollution, which is a pollution problem, more efficiently. Hydro-cyclone was added to the existing Filter column to create an Up-Flow Filtration system. The treatment efficiency according to the operating conditions such as turbidity, suspended solids, pH, inflow flow rate, and head loss was analyzed. Comparison of inflow water and runoff water suspended solids and turbidity analysis results showed a minimum treatment efficiency of 93.21% and a maximum treatment efficiency of 99% or more. It was analyzed that the SS and turbidity analysis results showed a treatment efficiency of 80% or more before and after backwashing twice. When Coagulation Hydro-cyclone was added compared to the existing filtration system, it was analyzed that particles that had not been treated as an adsorption fiber company filter medium between particles could be treated.

모유 수유아와 조제 분유 영양아에서 수유 방법에 따른 아미노산 농도 비교 및 혈청 트립토판 농도와 수면 유도와의 관계

정다운,김은영,양은석,박상기,박영봉,문경래 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Objective: Sleep behavior is modulated by serotonergic neurons within the brain, and the synthesis and release of serotonin by such neurons is thought to be influenced by the availability of tryptophan, the amino acid precursor of serotonin. Formula-feeding infants have depressed plasma tryptophan concentration relative to breast milk-feeding infants. Because tryptophan alters sleep waking patterns in adults, a study was designed to determine the difference of sleep latency relative to differences in plasma tryptophan and tryptophan : large neutral amino acid (LNAA) ratio between formula-feeding infants and breast milk-feeding infants. Method: 45 newborns who were born in Chosun University Hospital from December 2002 to December 2003 were selected. The newborns were divided to three group, 15 newborns were fed breast milk and 15 newborns were fed formula A, and last 15 newborns were fed formula B. At 6 weeks and 12 weeks, infants were sampled for measuring of serum amino acid level and tryptophan, tryptophan : LNAA ratio. And we taught infants' parents to measure sleep latency that means the time after a feeding to the first episode of active REM sleep that persist ≥ 1 min. Result: 1) At 6weeks, Serum α-amino-n-butyric acid, citrulline, tryptophan level was higher in formula A group than breastmilk group (P<0.05) and proline level was lower than breast milk group (P<0.05). In formula B group, serum n-amino-n-buryric acid, citrulline, cystine, hydroxylysine, hydroxyproline, isoleucine, leucine, lysine, methionine, phenylalanine, taurine, threonine, valine levels were higher than breastmilk group (P<0.05). And Serum isoleucine, methionine, proline, valine level were higher in formula B group than formula A group (P<0.05). 2) At 12 weeks, serum glutamic acid, methionine, ornithine levels were higher in formula group A than breast milk group (P<0.05). Serum β-alanine, aspartic acid, α-amino-n-butyric acid, ethanolamine, glutamic acid, threonine level were higher in formula B group than breast milk group (P<0.05). Serum β-alanine, ethanolamine levels were higher and arginine level was lower in formula B group than formula A (P<0.05). 3) At 6 weeks, serum tryptophan concentration and tryptophan: LNAA ratio were higher in formula A group (P<0.05). Sleep latency was 21 minutes in formula group A, 24 minutes in breast milk group, 25 minutes in formula B group but there was no statistically significance (P>0.05). 4) At 12 weeks, serum tryptophan concentration and tryptophan: LNAA ratio, time after feeding to the first episode of active REM sleep were no difference with each other group. Conclusion: There is significant difference of serum amino acids between breast-feeding infants and formula-feeding infants. And serum tryptophan and tryptophan: LNAA ratio differ between brest-feeding infants and formula-feeding infants. But there is no association between serum tryptophan, tryptophan: LNM ratio and sleep latency.

Development of Environmental Load Estimating Model for Maintaining NATM Tunnel

Da Ae Kim,Sang Tae Kim,Ju Hyun Lee,Kyoung Su Kim,Heung Rae Kim 한국도로학회 2018 한국도로학회 학술대회 발표논문 초록집 Vol.2018 No.05

The infrastructure that man absolutely needs creates a lot of environmental load. The environmental load is quantified global environment pollution. So we can use LCA method for assess and control environmental load. In this study, we developed the environmental load estimating model to evaluate quickly in design stage when maintaining infrastructures facilities. Especially, we chose NATM tunnel because it is economical and there are many example of construction on public roads and expressway. First, we made a list of the breakdown cost by using collected unit cost of Korea Expressway Corporation and Seoul-Si about tunnel maintenance. So we chose major work classification. We selected the major classification such as pavement repairing inside tunnel, leaked surface treatment of tunnel, attached tile repairing inside tunnel and tunnel cleaning etc. We excluded concrete repairing because it is not easy to define maintenance factor about concrete repairing. Next, we made data bases of standard supply and resources need by specialist work classification. Using data bases, we was able to estimate environmental load by designating an input variable such as lane, pavement, length, tile repairing, leaked surface treatment and cleaning method. Lastly, we made environmental load estimating model after it is verified by comparing the results with the actual environmental load and estimated environmental load. Finally, our goal of this study is to develop the methodology that easily estimates the environmental load. Accordingly, the environmental load will be decreased by using this model in stage of planning, design and maintenance. Also, it is expected that the maintenance management estimating model developed from this study will be possible to do eco-friendly management of the road and tunnel construction.

Inhibitory effect of withaferin A on Helicobacter pylori-induced IL-8 production and NF-κB activation in gastric epithelial cells

KIM, GREEN,KIM, TAE-HYOUN,KANG, MIN-JUNG,CHOI, JIN-A,PACK, DA-YOUNG,LEE, IK-RAE,KIM, MIN-GYU,HAN, SANG-SEOP,KIM, BO-YEON,OH, SANG-MUK,LEE, KYUNG-BOK,KIM, DONG-JAE,PARK, JONG-HWAN Spandidos Publications 2016 MOLECULAR MEDICINE REPORTS Vol. No.

Assessment of future climate and land use changes impact on hydrologic behavior in Anseong-cheon Gongdo urban-growing watershed

Kim, Da Rae,Lee, Yong Gwan,Lee, Ji Wan,Kim, Seong Joon 한국수자원학회 2018 한국수자원학회논문집 Vol.51 No.2

본 연구의 목적은 안성천 상류 공도유역(366.5km²)을 대상으로 SWAT 모형을 이용하여 미래 기후변화 평가에 있어, 미래의 토지이용변화를 동시에 고려하면 수문학적 거동에 얼마나 영향을 주는지를 분석하고자 하였다. 미래기후변화 시나리오는 HadGEM3-RA의 RCP 4.5와 8.5 시나리오를 이용하여 2030s (2020-2039)과 2050s (2040-2059) 기간으로 나누어 적용하였으며, 토지이용변화는 도시성장 시나리오에 따른 회귀모형 기반의 CLUE-s 모델을 이용하였다. 기준년(1976-2005) 대비 미래 강수량은 RCP 4.5에서 2030s에 최대 5.7%의 감소, 2050s에는 최대 18.5% 증가하였고, 미래 기온은 2030s RCP 4.5에서 최대 1.8°C, 2050s RCP 8.5에서 최대 2.6°C 증가하였다. 미래 토지이용은 2050년 도시지역이 58.6% (29.0 km²에서 46.0 km²) 증가하는 것으로 예측되었다. SWAT 수문 검보정은 14년(2002-2015) 동안의 공도관측소 일유량 자료를 이용하였으며, 저유량 모델효율의 향상을 위하여 2014-2015년 연속 가뭄년을 대상으로 보정을 실시한 결과, 하천유량(Q)과 1/Q을 대상으로Nash-Sutcliffe 모델효율은 각각 0.86과 0.76이었다. 미래 기후변화 시나리오만을 적용한 결과, 하천유출량이 2030s RCP 4.5에서 최대 24.2% 감소하다가 2050s RCP 4.5에서 최대 10.9% 증가하는 변화를 보여주었다. 한편, 기후변화와 더불어 미래의 토지이용변화를 함께 고려한 경우는 하천유출량이 2030s RCP 4.5에서 최대 14.9% 감소, 2050s RCP 4.5에서 최대 19.5% 증가하는 변화를 보여주어, 미래 기후변화에 따른 유역의 수문평가 시, 도시성장이 기대되는 유역 등 미래의 토지이용변화가 클 가능성이 있는 유역에 대해서는 토지이용변화 요소를 고려할 필요가 있다고 생각된다. The purpose of this study is to evaluate the future hydrologic behavior affected by the potential climate and land use changes in upstream of Anseong-cheon watershed (366.5 km²) using SWAT. The HadGEM3-RA RCP 4.5 and 8.5 scenarios were used for 2030s (2020-2039) and 2050s (2040-2059) periods as the future climate change scenario. It was shown that maximum changes of precipitation ranged from -5.7% in 2030s to +18.5% in 2050s for RCP 4.5 scenarios and the temperature increased up to 1.8°C and 2.6°C in 2030s RCP 4.5 and 2050s 8.5 scenarios respectively based on baseline (1976-2005) period. The future land uses were predicted using the CLUE-s model by establishing logistic regression equation. The 2050 urban area were predicted to increase of 58.6% (29.0 to 46.0 km²). The SWAT was calibrated and verified using 14 years (2002-2015) of daily streamflow with 0.86 and 0.76 Nash-Sutcliffe model efficiency (NSE) for stream flow (Q) and low flow 1/Q respectively focusing on 2 drought years (2014-2015) calibration. For future climate change only, the stream discharge showed maximum decrease of 24.2% in 2030s RCP 4.5 and turned to maximum increase of 10.9% in 2050s RCP 4.5 scenario compared with the baseline period stream discharge of 601.0 mm by the precipitation variation and gradual temperature increase. While considering both future climate and land use change, the stream discharge showed maximum decrease of 14.9% in 2030s RCP 4.5 and maximum increase of 19.5% in 2050s RCP 4.5 scenario by the urban growth and the related land use changes. The results supported that the future land use factor might be considered especially for having high potential urban growth within a watershed in the future climate change assessment.

Factors of Soil Properties and Elements in Tissues Influencing on Extent of Arsenic Accumulation in Brown Rice

Da-Young Kim,Kye-Hoon Kim,Danbi Lee,Mina Lee,Kwon-Rae Kim 한국토양비료학회 2020 한국토양비료학회지 Vol.53 No.1

Recently, As-contaminated soil management has started dealing with phytoavailable As content instead of total As content in soils. Phytoavailable As content is known to consider food safety more than the management of the environment. This study aims to predict As content in brown rice using phytoavailable As concentration in soil and soil properties and to see the relationship between element contents in tissues and As in brown rice. As-contaminated soils were collected, and their total and phytoavailable As content and soil properties were analyzed. Mehlich3 extraction method was used for phytoavailable As analysis. After the analysis, correlations among total and phytoavailable As concentrations in soils, As content in rice and soil properties were analyzed. Then, a prediction model of As content in brown rice was developed through multiple stepwise regression. Also, correlation analysis between nutrients and As contents in rice was conducted to identify the factors affecting As accumulation in brown rice. The modelling equation for estimating As concentration in brown rice was [Log (As in brown rice) = 2.45 + 0.13 × Log (As_Mehlich3) – 0.99 × Log (CEC) + 0.50 × Log (avail.-P)] (r = 0.49, p < 0.001). Soil avail.P concentration and CEC were valid variables for As accumulation in brown rice. In addition, Cu, Zn, Mo and Na in shoot were revealed to influence governing translocation of As from shoot to grain.

Chemical Characterization and Oxidative Stability of Medium- and Long-Chain Fatty Acid Profiles in Tree-Borne Seed Oils

Kim, Da-Som,Kim, Hoe-Sung,Lee, Kyoung-Tae,Hong, Dong-Lee,Cho, Sung-Rae,Pan, Jeong Hoon,Park, Yong Bae,Lee, Yang-Bong,Kim, Jae Kyeom,Shin, Eui-Cheol Hindawi 2018 Journal of analytical methods in chemistry Vol.2018 No.-

<P>This study was undertaken to evaluate chemical characteristics and oxidative stability of tree-borne seed oils. A total of 15 different fatty acids were identified in six tree-borne seed oils, which included seven types of saturated fatty acids, four types of monounsaturated fatty acids, and four types of polyunsaturated fatty acids. Japanese camphor tree (JCT) had a high content of medium-chain fatty acids (97.94 ± 0.04%), in which fatty acid composition was distinct from those of the other five plant seed oils. Overall, contents of tocopherols, a type of fat-soluble vitamin, ranged between 3.82 ± 0.04 mg/100 g and 101.98 ± 1.34 mg/100 g, respectively. Phytosterol contents ranged from 117.77 ± 1.32 mg/100 g to 479.45 ± 4.27 mg/100 g, respectively. Of all tree-borne seed oils, <I>β</I>-sitosterol was the phytosterol at the highest concentration. Contents of unsaponifiables were between 0.13 ± 0.08 and 2.01 ± 0.02, and values of acid, peroxide, and <I>p</I>-anisidine were between 0.79 ± 0.01 and 38.94 ± 0.24 mg KOH/g, 3.53 ± 0.21 and 127.67 ± 1.79 meq/kg, and 2.07 ± 0.51 and 9.67 ± 0.25, respectively. Oxidative stability of tree-borne seed oils was assessed through measurement of oxidation-induction periods. These results should serve as a foundation to identify the potential of tree-borne seed oils in industrial application as well as in providing fundamental data.</P>

Case Report : Severe Hyponatremia Associated with the Use of Angiotensin II Receptor Blocker/thiazide Combinations

( Da Rae Kim ),( Joo Hee Cho ),( Won Seok Jang ),( Jin Sug Kim ),( Kyung Hwan Jeong ),( Tae Won Lee ),( Chun Gyoo Ihm ) 대한전해질학회 2013 Electrolytes & Blood Pressure Vol.11 No.2

There are several widely used combinations of angiotensin II receptor blocker (ARB)/ thiazide. The complimentary mechanism of action for such antihypertensive therapies is that, while ARB inhibits the vasoconstricting and aldosterone-secreting effects of angiotensin II, hydrochlorothiazide affects the renal tubular mechanisms of electrolyte reabsorption and increases excretion of sodium and chloride in the distal tubule, consequently promoting water excretion. In addition, hypokalemia, which may be triggered by a hydrochlorothiazide-induced increase in urinary potassium loss, is resisted by the use of ARB. Hence, the ARB/thiazide combination is safe in terms of potassium imbalance. For these reasons, fixed-dose ARB/thiazide combination anti-hypertensive drugs have been widely used for the treatment of hypertension. However, there have not been many studies done regarding cases where patients under such regimens showed severe hyponatremia,even when the amount of thiazide included was low. Here we report two cases in which severe hyponatremia occurred following treatment with the ARB/thiazide combinations. Upon discontinuation of the regimen, both patients showed recovery from hyponatremia.

A novel real-time PCR method based on signaling-by-incorporation

Kim, Da-Rae,Ahn, Hee-Chul,Lee, Won-Ja,Ahn, Dae-Ro Royal Society of Chemistry 2011 Chemical communications Vol.47 No.2

<P>We describe a novel real-time PCR method, which utilizes the <I>in situ</I> generated signal upon incorporation of a fluorogenic nucleotide. The method has been compared with a conventional method and evaluated for practical uses such as quantification of cDNA and malaria diagnosis.</P> <P>Graphic Abstract</P><P>A modified dGTP can be used as a fluorogenic probe for real-time PCR. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c0cc04516k'> </P>

HBV : PO-04 ; Antiviral efficacy of entecavir and adefovir combination therapy in chronic hepatitis B patients with previous nucleos(t)ide analogues failures

( Da Rae Kim ),( Young Eun Chon ),( Sang Hoon Ahn ),( Ha Na Park ),( Seung Up Kim ),( Do Young Kim ),( Kwang Hyub Han ),( Chae Yoon Chon ),( Jun Yong Park ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1

Background: Entecavir (ETV) and adefovir (ADV) combination can be used as a rescue therapy for patients who had failed nucleos(t)ide analogues where tenofovir has not been introduced. We evaluated the efficacy of ETV and ADV combination therapy in patients who had failed to previous nucleos(t)ide analogue (NA). Methods: This study included consecutive 66 compensated chronic hepatitis B (CHB) patients who have failed to previous NAs. All patients received ETV and ADV combination therapy for at least 6 months. While all of the patients had experienced lamivudine (LAM), 48 (72.7%) had experienced ADV and 53 (80.3%) had been treated with ETV. Genetic resistance to LAM, ADV, and ETV at baseline were detected in 65 (98.5%), 12 (18.2%), and 36 (54.5%), respectively. Results: Median HBV DNA level was 5.63 (1.86~8.23) log IU/mL and fifty nine patients had HBeAg positivity. During a median of 15 (6-38) months of ETV and ADV combination therapy, virological response (VR, < 60 IU/mL by PCR assay) was achieved in 18 of 66 (27.3%) patients. Cumulative VR rates were 21.5%, 28.4%, 36.6% and 36.6% at 6, 12, 24 and 36 months, respectively. When we investigated predictors for VR, baseline ADV resistance along with low baseline ALT level (p=0.027) were significantly associated with decreased VR from multivariate analysis. Conclusions: ETV and ADV combination rescue therapy showed limited efficacy for CHB patients who had failed to previous NAs, however, it can be considered as a rescue therapy in patients who do not have resistance to ADV and high baseline ALT level.