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Chen, Nai-Zhi,Zhang, Xiu-Qing,Wei, Peng-Cheng,Chen, Qi-Jun,Ren, Fei,Chen, Jia,Wang, Xue-Chen Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.6
The HAP complex has been found in many eukaryotic organisms. HAP recognizes the CCAAT box present in the promoters of 30% of all eukaryotic genes. The HAP complex consists of three subunits - HAP2, HAP3 and HAP5. In this paper, we report the biological function of the AtHAP3b gene that encodes one of the HAP3 subunits in Arabidopsis. Compared with wild-type plants, hap3b-1 and hap3b-2 mutants exhibited a delayed flowering time under long-day photoperiod conditions. Moreover, the transcription levels of FT were substantially lower in the mutants than in the wild-type plants. These results imply that AtHAP3b may function in the control of flowering time by regulating the expression of FT in Arabidopsis. In a subsequent study, AtHAP3b was found to be induced by osmotic stress. Under osmotic stress conditions, the hap3b- 1 and hap3b-2 mutants flowered considerably later than the wild-type plants. These results suggest that the AtHAP3b gene plays more important roles in the control of flowering under osmotic stress in Arabidopsis.
Altered mRNA Levels of MOV10, A3G, and IFN-α in Patients with Chronic Hepatitis B
Zhi-Wei Song,Yan-Xiu Ma,Li-Juan Fu,Bao-qing Fu,Xu Teng,Si-Jia Chen,Wei-Zhen Xu,Hong-Xi Gu 한국미생물학회 2014 The journal of microbiology Vol.52 No.6
To explore the relationship of the MOV10, A3G, and IFN-αmRNA levels with chronic hepatitis B virus (HBV) infection,Blood samples from 96 patients with chronic hepatitis B(CHB) and 21 healthy individuals as control were collected. HBV DNA load and aminotransferase in the serum weretested using real time PCR and velocity methods, respectively. The MOV10, A3G, and IFN-α mRNA levels in theperipheral blood mononuclear cells (PBMC) were examinedthrough qRT-PCR. The MOV10, A3G, and IFN-α mRNAlevels in CHB group was significantly lower than those inthe control group (P<0.01, P<0.05, P<0.01, respectively). TheA3G mRNA level in the high-HBV DNA load group waslower than that in the low-HBV DNA load group (P<0.05). However, no statistical difference was found in the MOV10and IFN-α mRNA levels between the two HBV DNA loadgroups. Furthermore, the MOV10 mRNA level showed positivecorrelation with IFN-α in the control group. These resultsindicated that the expression of the innate immune factorsMOV10, A3G, and IFN-α is affected by chronic HBV infection.
Zhi-Wei Chen,Weibiao Yang,Jun LI,Qifeng Cheng,Qinlin Cai 사단법인 한국계산역학회 2017 Computers and Concrete, An International Journal Vol.20 No.5
Ordinary reinforced concrete (RC) and prestressed concrete bridges are two popular and typical types of short- and medium-span bridges that accounts for the vast majority of all existing bridges. The cost of maintaining, repairing or replacing degraded existing RC bridges is immense. Detecting the abnormality of RC bridges at an early stage and taking the protective measures in advance are effective ways to improve maintenance practices and reduce the maintenance cost. This study proposes a systematic method from influence line (IL) identification to damage detection with applications to RC bridges. An IL identification method which integrates the cubic B-spline function with Tikhonov regularization is first proposed based on the vehicle information and the corresponding moving vehicle induced bridge response time history. Subsequently, IL change is defined as a damage index for bridge damage detection, and information fusion technique that synthesizes ILs of multiple locations/sensors is used to improve the efficiency and accuracy of damage localization. Finally, the feasibility of the proposed systematic method is verified through experimental tests on a three-span continuous RC beam. The comparison suggests that the identified ILs can well match with the baseline ILs, and it demonstrates that the proposed IL identification method has a high accuracy and a great potential in engineering applications. Results in this case indicate that deflection ILs are superior than strain ILs for damage detection of RC beams, and the performance of damage localization can be significantly improved with the information fusion of multiple ILs.
Cancer Registration in the Peoples Republic of China
Wei, Kuang-Rong,Chen, Wan-Qing,Zhang, Si-Wei,Liang, Zhi-Heng,Zheng, Rong-Shou,Ou, Zhi-Xiong Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
The current situation of cancer registration in China was systematically reviewed. So far, cancer registration in China has been making a great progress in the following aspects: the number of cancer registries and covered population have increased dramatically; a registration network has been established and completed gradually; regulations and rules improved remarkably; more attention is being paid by every level of government; a lot of registration software has been created and financial support ensured. However, we are still facing some problems and challenges, such as no stable groups of registrars, shortage of training opportunities, poor data quality, insufficient utilization and lack of multidisciplinary mechanisms, so that the cancer registration system still needs to be enhanced and improved. Along with the development of economy, science and information technology, methods and patterns of cancer registration is changing. It is to be expected that cancer registration will be automatic, nationwide and integrated with community healthcare in the near future.
An Improved Method of Maximum Power Point Tracking Strategy for Wind Power Conversion System
CHEN Ran,CHEN Jie,CHEN Jia-wei,CHEN Zhi-hui,GONG Chun-ying,YAN Yang-guang 전력전자학회 2011 ICPE(ISPE)논문집 Vol.2011 No.5
The turbine speed loop adjustment is the key link of the designing of the controller for the fixed pitch variable speed wind energy conversion systems (WECS). Because of the strong nonlinear, big inertia and mechanical damping characteristics, it’s difficult to designing the controller of the wind power systems. In this paper, a small signal model is present, and based on the analyzing; a wind turbine speed loop regulator is designed. Then, a method of tracking the peak power conversion system is proposed, which is independent of the turbine parameters and air density. At last, simulation system is built, and the results of the simulation experiments show that, the performance of the controller algorithm meet the requirements of the MPPT without wind measurement.
The Phytotoxic Effects of Selenium–Mercury Interactions on Root Growth in Brassica rapa (LvLing)
Zhi-Wei Bian,Jian Chen,Hui Li,Dan-Dan Liu,Li-Fei Yang,Yue-Lin Zhu,Wen-Li Zhu,Wei Liu,Zheng-Zheng Ying 한국원예학회 2016 Horticulture, Environment, and Biotechnology Vol.57 No.3
Rapid industrial and agricultural development has dramatically increased the emission of selenium (Se) and mercury (Hg) into the environment. Combined soil pollution by Se and Hg poses a potential threat to crop production. However, no toxic effects of Hg–Se interactions on plants have been reported previously. In this study, we investigated the effects of Hg–Se interactions on biochemical and physiological indices in the roots of Brassica rapa (LvLing). Seedlings were treated hydroponically with solutions of mercury chloride (1 μM), sodium selenite (4 μM), or a combination of the two. Combined Hg+Se treatment significantly inhibited root growth, reduced root biomass, and enhanced reactive oxygen species (ROS) and malondialdehyde accumulation and led to a loss of plasma membrane integrity. The combined treatment increased glutathione peroxidase, glutathione S-transferase, and peroxidase activity, reduced superoxide dismutase activity, and had no effect on catalase activity. In addition, we detected increased glutathione concentrations in root tips and reduced ascorbic acid concentrations in the presence of Hg+Se relative to individual treatments with these elements. Thus, Hg–Se interactions enhanced oxidative injury, cell death, and phytotoxicity in B. rapa roots.
Automatic balancing of a flexible supported rotor with two disks by two ball balancers
Hai-Wei Chen,Yan-Bin Chen,Zhen Sun,Zhi Wang 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.7
This paper studies automatic balancing of a flexible supported rotor with two disks by two ball balancers. Firstly, reduced dynamic descriptions of different components in the rotor are derived using a special method according to Lagrangian equation, based on which a general vibration model of the rotor system is then constructed. Secondly, equations governing frequency responses of the rotor are derived and working principles of the balls in the rotor are illustrated based on basic dynamic phenomena. Thirdly, an autonomous model of the rotor system is built with equations governing movement of the balls derived. Three equilibrium solutions are discovered whose dynamic characteristics are then studied using numerical bifurcation analysis method. Finally, locations of the balls at the steady state are observed using a high speed camera, and the capability of the two balancers for automatic balancing under different conditions is validated.
On the die face design for stamping an automotive engine hood
Ming-Zhi Chen,Fuh-Kuo Chen,Shi-Wei Wang,Ching-I Lin 한국소성가공학회 2010 기타자료 Vol.2010 No.6
The die face design for stamping an engine hood was examined in the present study using both the finite element analysis and the experimental approach. Since the engine hood is mainly manufactured in the drawing operation, the die addendum design is the key to the success of manufacturing a defect free product. In order to analyze the addendum design, the existing die addendum designs corresponding to those engine hoods were reviewed first and the design parameters were established. The preliminary study was then performed to determine favorable operation conditions including the suitable stamping die angle, blank-holder surface shape, and die open line. The optimum design for the die addendum face was then investigated with the use of finite element simulations. The effects of the design parameters constructed in the present study on the occurrence of the defects were examined and a systematic design guideline was proposed. In order to validate the proposed die design, the actual stamping tooling was manufactured according to the finite element analysis and the engine hoods were produced. The part shape, thickness distribution, and the stretch at the central region of the production part were compared with those obtained from the finite element simulations. The consistent agreement between the product parts and the simulation results confirms the validity of the design guide proposed in the present study for stamping an engine hood.