http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Yuxiang Gao (검색결과 5 건)
- 무료
- 기관 내 무료
- 유료
-
Yuxiang Zhang,Xiaoling Liang,Shuzhi Sam Ge,Bingzhao Gao,Tong Heng Lee 제어로봇시스템학회 2021 제어로봇시스템학회 국제학술대회 논문집 Vol.2021 No.10
Guaranteed safety and performance under various circumstances remain technically critical and practically challenging for the wide deployment of autonomous vehicles. For such safety-critical systems, it will certainly be a requirement that safe performance should be ensured even during the reinforcement learning period in the presence of system uncertainty. To address this issue, a Barrier Lyapunov Function-based safe reinforcement learning algorithm (BLF- SRL) is proposed here for the formulated nonlinear system in strict-feedback form. This approach appropriately arranges the Barrier Lyapunov Function item into the optimized backstepping control method to constrain the state-variables in the designed safety region during learning when unknown bounded system uncertainty exists. More specifically, the overall system control is optimized with the optimized backstepping technique under the framework of Actor-Critic, which optimizes the virtual control in every backstepping subsystem. Wherein, the optimal virtual control is decomposed into Barrier Lyapunov Function items; and also with an adaptive item to be learned with deep neural networks, which achieves safe exploration during the learning process. Eventually, the principle of Bellman optimality is satisfied through iteratively updating the independently approximated actor and critic to solve the Hamilton-Jacobi-Bellman equation in adaptive dynamic programming. More notably, the variance of control performance under uncertainty is also reduced with the proposed method. The effectiveness of the proposed method is verified with motion control problems for autonomous vehicles through appropriate comparison simulations.
-
Plasma-catalytic decomposition of ethyl acetate over LaMO3 (M = Mn, Fe, and Co) perovskite catalysts
Yuxiang Cai,Xinbo Zhu,Wenshuo Hu,Chenghang Zheng,Yangyang Hu,Menghan Chen,Xiang Gao 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.70 No.-
Plasma-catalytic decomposition of low concentration ethyl acetate with LaMO3 (M = Co, Mn and Fe)perovskite catalyst was investigated in a coaxial dielectric barrier discharge (DBD) reactor. Thecombination of perovskite catalyst and plasma enhanced ethyl acetate decomposition, and the activitysequence was LaCoO3> LaMnO3> LaFeO3. Characterizations results indicated that the activation ofsurface oxygen species and amount of oxygen vacancies contributed to ethyl acetate decompositionremarkably. FT-IR analysis demonstrated that the employment of LaCoO3 catalyst also reduced theamount of unwanted by-products. Based on these results, reaction mechanism of ethyl acetate plasmacatalyticdecomposition process was proposed.
-
Xinjie Gao,Heng Yang,Weiping Xiao,Jiabin Su,Yuwen Zhang,He Wang,Wei Ni,Yuxiang Gu 한국생체재료학회 2022 생체재료학회지 Vol.26 No.4
Background: Despite limited efficiency, modulation of microglia/macrophages has shown to attenuate neuroinflammation after intracerebral hemorrhage (ICH). In this context, we evaluated the efficacy of modified exosomal signal regulatory protein α (SIRPα) variants (SIRPα-v Exos) in microglia/macrophages and neuroinflammation-associated white matter injury after ICH. Methods: SIRPα-v Exos were engineered to block CD47-SIRPα interactions. After obtaining SIRPα-v Exos from lentivirus-infected mesenchymal stem cells, C57BL/6 mice suffering from ICH underwent consecutive intravenous injections of SIRPα-v Exos (6 mg/kg) for 14 days. Afterwards, the volume of hematoma and neurological dysfunctions were assessed in mice continuously until 35 days after ICH. In addition, demyelination, electrophysiology and neuroinflammation were evaluated. Furthermore, the mechanisms of microglial regulation by SIRPα-v Exos were investigated in vitro under coculture conditions. Results: The results demonstrated that the clearance of hematoma in mice suffering from ICH was accelerated after SIRPα-v Exo treatment. SIRPα-v Exos improved long-term neurological dysfunction by ameliorating white matter injury. In addition, SIRPα-v Exos recruited regulatory T cells (Tregs) to promote M2 polarization of microglia/macrophages in the peri-hematoma tissue. In vitro experiments further showed that SIRPα-v Exos regulated primary microglia in a direct and indirect manner in synergy with Tregs. Conclusion: Our studies revealed that SIRPα-v Exos could accelerate the clearance of hematoma and ameliorate secondary white matter injury after ICH through regulation of microglia/macrophages. SIRPα-v Exos may become a promising treatment for ICH in clinical practice.
-
Li, Gao,Abroshan, Hadi,Chen, Yuxiang,Jin, Rongchao,Kim, Hyung J. American Chemical Society 2015 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.137 No.45
<P>The catalytic activity of Au<SUB>25</SUB>(SR)<SUB>18</SUB> nanoclusters (R = C<SUB>2</SUB>H<SUB>4</SUB>Ph) for the aldehyde hydrogenation reaction in the presence of a base, e.g., ammonia or pyridine, and transition-metal ions M<SUP>z+</SUP>, such as Cu<SUP>+</SUP>, Cu<SUP>2+</SUP>, Ni<SUP>2+</SUP> and Co<SUP>2+</SUP>, as a Lewis acid is studied. The addition of a Lewis acid is found to significantly promote the catalytic activity of Au<SUB>25</SUB>(SR)<SUB>18</SUB>/CeO<SUB>2</SUB> in the hydrogenation of benzaldehyde and a number of its derivatives. Matrix-assisted laser desorption ionization (MALDI) and electrospray ionization (ESI) mass spectrometry in conjunction with UV–vis spectroscopy confirm the generation of new species, Au<SUB>25-<I>n</I></SUB>(SR)<SUB>18-<I>n</I></SUB> (<I>n</I> = 1–4), in the presence of a Lewis acid. The pathways for the speciation of Au<SUB>24</SUB>(SR)<SUB>17</SUB> from its parent Au<SUB>25</SUB>(SR)<SUB>18</SUB> nanocluster as well as its structure are investigated via the density functional theory (DFT) method. The adsorption of M<SUP><I>z</I>+</SUP> onto a thiolate ligand “SR” of Au<SUB>25</SUB>(SR)<SUB>18</SUB>, followed by a stepwise detachment of “SR” and a gold atom bonded to “SR” (thus an “Au-SR” unit) is found to be the most likely mechanism for the Au<SUB>24</SUB>(SR)<SUB>17</SUB> generation. This in turn exposes the Au<SUB>13</SUB>-core of Au<SUB>24</SUB>(SR)<SUB>17</SUB> to reactants, providing an active site for the catalytic hydrogenation. DFT calculations indicate that M<SUP>z+</SUP> is also capable of adsorbing onto the Au<SUB>13</SUB>-core surface, producing a possible active metal site of a different kind to catalyze the aldehyde hydrogenation reaction. This study suggests, for the first time, that species with an open metal site like adducts [nanoparticle-M]<SUP>(<I>z</I>-1)+</SUP> or fragments Au<SUB>25-<I>n</I></SUB>(SR)<SUB>18-<I>n</I></SUB> function as the catalysts rather than the intact Au<SUB>25</SUB>(SR)<SUB>18</SUB>.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/2015/jacsat.2015.137.issue-45/jacs.5b07716/production/images/medium/ja-2015-07716c_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja5b07716'>ACS Electronic Supporting Info</A></P>
-
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
